No. Biomarker_type Function_type Biomarker_symbol Species Tissue_or_sample Cancer_type Cancer_subtype Expression(Adverse risk) Reference type PMID Article_title 1 circRNA diagnostic biomarker "combine(hsa_circ_0062019,hsa_circ_0057558)" human tissue prostate cancer H original research 30396163 Circular RNA Expression Profiling Identifies Prostate Cancer-Specific circRNAs in Prostate Cancer. 2 circRNA diagnostic biomarker circ-AGFG1 human tissue breast cancer triple-negative breast cancer H original research 30621700 The circRNA circAGFG1 acts as a sponge of miR-195-5p to promote triple-negativebreast cancer progression through regulating CCNE1 expression. 3 circRNA diagnostic biomarker "combine(hsa_circ_0000096,hsa_circ_002059),circ-TCF25,hsa_circ_0001649,hsa_circ_0003159,hsa_circ_0004018,hsa_circ_0005986,hsa_circ_0006633,hsa_circ_001988,hsa_circ_002059,hsa_circ_103809" human "tissue,tissue,tissue,tissue,tissue,tissue,uncertain,tissue,tissue,plasma,tissue" uncertain Multiple cancers L review 29349062 "Circular RNAs: Biogenesis, Function, and a Role as Possible Cancer Biomarkers." 4 circRNA diagnostic biomarker "combine(hsa_circ_0001874,hsa_circ_0001971)" human "saliva,blood,uncertain,tissue" oral cancer oral squamous cell carcinoma H original research 29991057 Salivary Circular RNAs Hsa_Circ_0001874 and Hsa_Circ_0001971 as Novel Biomarkers for the Diagnosis of Oral Squamous cell Carcinoma 5 circRNA diagnostic biomarker "combine(hsa_circ_0004018,hsa_circ_0003570,hsa_circ_0005075)" human tissue hepatocellular cancer H review 29856133 Circular RNAs in hepatocellular carcinoma: Functions and implications. 6 circRNA diagnostic biomarker "combine(hsa_circ_00156,hsa_circ_000224,hsa_circ_000520)" human serum hepatocellular cancer uncertain original research 30426540 "circRNAs (hsa_circ_00156, hsa_circ _000224, and hsa_circ _000520) are novel potential biomarkers in hepatocellular carcinoma" 7 circRNA diagnostic biomarker "combine(hsa_circ_001937,hsa_circ_000178)" human "plasma,serum" uncertain Multiple cancers H review 30259364 Emerging Role of Circular RNAs as Potential Biomarkers for the Diagnosis of Human Diseases. 8 circRNA diagnostic biomarker "combine(hsa_circ_006054,hsa_circ_100219,hsa_circ_406697),circ-CER,hsa_circ_0000745,hsa_circ_0000190,hsa_circ_0001649" human "tissue,tissue,plasma,uncertain,uncertain" uncertain Multiple cancers "L(hsa_circ_0000190,Hsa_circ_0001649)" review 30064463 Function and clinical significance of circRNAs in solid tumors 9 circRNA diagnostic biomarker "combine(hsa_circ_0091017,hsa_circ_0002024)" human tissue bladder cancer L original research 29151929 Identification of circular RNA signature in bladder cancer. 10 circRNA diagnostic biomarker "combine(hsa_circ_103110,hsa_circ_104689,hsa_circ_104821,hsa_circ_006054,hsa_circ_100219,hsa_circ_406697)" human tissue breast cancer "H(hsa_circ_103110,hsa_circ_104689,hsa_circ_104821),L(hsa_circ_006054,hsa_circ_100219,hsa_circ_406697)" original research 28484086 Identification of circular RNAs as a promising new class of diagnostic biomarkersfor human breast cancer. 11 circRNA diagnostic biomarker "combine(hsa_circ_103809,hsa_circ_104700)" human tissue colorectal cancer L original research 28349836 Identification of differentially expressed circular RNAs in human colorectal cancer. 12 circRNA diagnostic biomarker "hsa_circ_0001178,hsa_circ_0000826" human tissue colorectal cancer H original research 30630466 RNA-Seq profiling of circular RNAs in human colorectal Cancer liver metastasis and the potential biomarkers 13 circRNA diagnostic biomarker hsa_circ_0002138 human tissue colorectal cancer L original research 30841415 Circular RNA circ_0002138 is down-regulated and suppresses cell proliferation in colorectal cancer 14 circRNA diagnostic biomarker hsa_circ_0003906 human tissue colorectal cancer L original research 29123417 The expression profile and clinical significance of circRNA0003906 in colorectal cancer 15 circRNA diagnostic biomarker "hsa_circ_0003906,hsa_circ_0000181,hsa_circ_0000745,hsa_circ_0000190,hsa_circ_0128298" human "tissue,plasma,uncertain,uncertain" uncertain Multiple cancers uncertain review 30411680 Circular RNAs Serve as Novel Biomarkers and Therapeutic Targets in Cancers 16 circRNA diagnostic biomarker hsa_circ_001988 human uncertain uncertain uncertain review 30805658 "Comprehensive analysis of circular RNAs in pathological states: biogenesis, cellular regulation, and therapeutic relevance " 17 circRNA diagnostic biomarker hsa_circ_0026 human tissue gastric cancer L original research 28737829 Expression profile of circular RNAs in human gastric cancer tissues 18 circRNA diagnostic biomarker hsa_circ_0043898 human tissue esophageal cancer L original research 30252576 Circ0043898 acts as a tumor inhibitor and performs regulatory effect on the inhibition of esophageal carcinoma 19 circRNA diagnostic biomarker hsa_circ_100338 human tissue hepatocellular cancer H(has_circ_0005075) review 30191143 Prospect of Circular RNA in Hepatocellular Carcinoma: A Novel Potential Biomarker and Therapeutic Target. 20 circRNA diagnostic biomarker hsa_circ_100876 human tissue uncertain Multiple cancers uncertain review 29928954 The emerging role of circRNAs and their clinical significance in human cancers 21 circRNA diagnostic biomarker "hsa_circ_100876,hsa_circ_0000096,hsa_circ_0001649,hsa_circ_0004277,hsa_circ_002059,hsa_circ_100855,hsa_circ_104912" human "uncertain,tissue,cell,tissue,uncertain,uncertain,uncertain" uncertain Multiple cancers "H(hsa_circ_002059,hsa_circ_001988),L(Hsa_circ_0000069,circCCNB,circCDK13,circCCDC66,)" review 28969099 Regulation of microRNAs function by circular RNAs in human cancer 22 circRNA diagnostic biomarker hsa_circ_104075 human tissue hepatocellular cancer H original research 30361504 circRNA_104075 stimulates YAP-dependent tumorigenesis through the regulation of HNF4a and may serve as a diagnostic marker in hepatocellular carcinoma 23 circRNA diagnostic biomarker hsa_circ_8924 human tissue cervical cancer H original research 30007986 "CircRNA8924 Promotes Cervical Cancer cell Proliferation, Migration and Invasion by Competitively Binding to MiR-518d-5p /519-5p Family and Modulating the Expression of CBX8." 24 circRNA diagnostic biomarker circ-ADAMTS14 human tissue hepatocellular cancer L original research 30317540 The competing endogenous circular RNA ADAMTS14 suppressed hepatocellular carcinoma progression through regulating microRNA-572/regulator of calcineurin 1. 25 circRNA diagnostic biomarker "circ-BNC2,circ-EXOC6B,circ-FAM13B,circ-N4BP2L2,circ-RHOBTB3,circ-CELSR1" human tissue ovarian cancer epithelial ovarian cancer uncertain original research 30272264 Circular RNA profiling reveals circEXOC6B and circN4BP2L2 as novel prognostic biomarkers in epithelial ovarian cancer. 26 circRNA diagnostic biomarker circ-CBFB human cell leukemia chronic lymphocytic leukemia H original research 29902450 Circular RNA circ-CBFB promotes proliferation and inhibits apoptosis in chronic lymphocytic leukemia through regulating miR-607/FZD3/Wnt/¦Â-catenin pathway 27 circRNA diagnostic biomarker circ-CDR1as human serum uncertain H review 26138677 Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis 28 circRNA diagnostic biomarker circ-DOCK1 human tissue oral cancer oral squamous cell carcinoma L original research 29286141 CircDOCK1 suppresses cell apoptosis via inhibition of miR?196a?5p by targeting BIRC3 in OSCC 29 circRNA diagnostic biomarker "circ-FARSA,hsa_circ_0012673" human "plasma,tissue" lung cancer "H(Hsa_circ_0014130,hsa_circ_0079530,hsa_circ_0013958)" review 30400981 Progress in research on the role of circular RNAs in lung cancer 30 circRNA diagnostic biomarker hsa_circ_0010090 mice tissue hepatocellular cancer H original research 30053867 circFBLIM1 act as a ceRNA to promote hepatocellular cancer progression by sponging miR-346 31 circRNA diagnostic biomarker hsa_circ_005239 mice "tissue,cell " breast cancer triple negative breast cancer H original research 29037220 circGFRA1 and GFRA1 act as ceRNAs in triple negative breast cancer by regulating miR-34a 32 circRNA diagnostic biomarker circ-HIPK3 human "cell,plasma,tissue" osteosarcoma L original research 29805712 "Circular RNA circ_HIPK3 is down-regulated and suppresses cell proliferation, migration and invasion in osteosarcoma" 33 circRNA diagnostic biomarker hsa_circ_0000284 human tissue gallbladder cancer H original research 29928876 Circular RNA HIPK3 promotes gallbladder cancer cell growth by spongingmicroRNA-124. 34 circRNA diagnostic biomarker "circ-KLDHC10,circ-FAT1,circ-RTN4" human uncertain uncertain Multiple cancers H(LINC-ROR) review 29558960 The decade of exosomal long RNA species: an emerging cancer antagonist. 35 circRNA diagnostic biomarker "circ-KLDHC10,hsa_circ_0013958" human "tissue,tissue,plasma" uncertain Multiple cancers uncertain review 29433541 "Circular RNAs: Biogenesis, Function, and a Role as Possible Cancer Biomarkers." 36 circRNA diagnostic biomarker hsa_circ_0006988 human "tissue,plasma" pancreatic cancer H original research 29307994 Circular RNA circ-LDLRAD3 as a biomarker in diagnosis of pancreatic cancer 37 circRNA diagnostic biomarker hsa_circ_0092509 human uncertain osteosarcoma H original research 29383123 Circular RNA circ-NT5C2 acts as an oncogene in osteosarcoma proliferation and metastasis through targeting miR-448. 38 circRNA diagnostic biomarker hsa_circ_0036627 human tissue pancreatic cancer H original research 29709702 Tumor-released exosomal circular RNA PDE8A promotes invasive growth via the miR-338/MACC1/MET pathway in pancreatic cancer. 39 circRNA diagnostic biomarker hsa_circ_0003221 human tissue bladder cancer H review 29125888 Circular RNA hsa_circ_0003221 (circPTK2) promotes the proliferation and migration of bladder cancer cells 40 circRNA diagnostic biomarker circ-PVT1 human "cell,tissue,serum" osteosarcoma H original research 29559849 "Overexpressed circPVT1, a potential new circular RNA biomarker, contributes to doxorubicin and cisplatin resistance of osteosarcoma cells by regulating ABCB1" 41 circRNA diagnostic biomarker circ-PVT1 human tissue colorectal cancer uncertain original research 30585259 Prediction of CircRNA-Disease Associations Using KATZ Model Based on Heterogeneous Networks 42 circRNA diagnostic biomarker "circ-PVT1,F-circEA" human "tissue,tissue" uncertain Multiple cancers "H(has_circ_0000977),L(circPVT1,circGFRA1)" review 30111313 Emerging function and potential diagnostic value of circular RNAs in cancer. 43 circRNA diagnostic biomarker hsa_circ_0000285 human tissue nasopharyngeal cancer H original research 30405788 Upregulation of circRNA_0000285 serves as a prognostic biomarker for nasopharyngeal carcinoma and is involved in radiosensitivity. 44 circRNA diagnostic biomarker hsa_circ_100338 human tissue hepatocellular cancer H original research 28710406 Comprehensive circular RNAprofiling reveals the regulatory roleof the circRNA-100338/miR-141-3ppathway in hepatitis B-relatedhepatocellular carcinoma 45 circRNA diagnostic biomarker circ-Seq human tissue breast cancer uncertain original research 27829232 Circular RNAs and their associations with breast cancer subtypes 46 circRNA diagnostic biomarker "circ-SKA3,circ-DTL" human tissue medulloblastoma H original research 30402980 Dysregulated circular RNAs in medulloblastoma regulate proliferation and growth of tumor cells via host genes. 47 circRNA diagnostic biomarker circ-SMAD7 human "plasma,tissue" esophageal cancer esophageal squamous cell carcinoma L original research 30611100 Up-regulation of circ-SMAD7 inhibits tumor proliferation and migration in esophageal squamous cell carcinoma 48 circRNA diagnostic biomarker circ-TTC17 human "cell,plasma,tissue" esophageal cancer esophageal squamous cell carcinoma H original research 30519852 Circ-TTC17 Promotes Proliferation and Migration of Esophageal Squamous cell Carcinoma 49 circRNA diagnostic biomarker "circ-ZKSCAN1,ciRS-7,hsa_cir_0005075,hsa_circ_0001649,hsa_circ_0003570,hsa_circ_0004018,hsa_circ_0005986" human "tissue,cell,tissue,tissue,tissue, tissue,serum,uncertain,tissue,cell,tissue,cell," hepatocellular cancer "H(CircHIPK3,Hsa_circ_100338,Hsa_circ_0005075,CircRNA_000839),L(circMTO1,ZKSCAN1,Hsa_circ_0001649,hsa_circ_0005986,circ-ITCH,hsa_cir_0004018,hsa_cir_0003570)" review 29760792 The Emerging Role of Circular RNAs in Hepatocellular Carcinoma 50 circRNA diagnostic biomarker "circ-ZKSCAN1,hsa_circ_0005075,hsa_circ_0016788,hsa_circ_0128298,hsa_circ_100338" human "tissue,tissue,tissue,tissue,tissue" hepatocellular cancer "H(Hsa_circ_0128298),L(hsa_circ_0068669,Hsa_circ_0003570,hsa_circ_0001445)" review 30072625 "Circular RNAs: Characteristics, Function and Clinical Significance in Hepatocellular Carcinoma" 51 circRNA diagnostic biomarker hsa_circ_0001727 human "tissue,cell" hepatocellular cancer L original research 28211215 "ZKSCAN1 gene and its related circular RNA (circZKSCAN1) both inhibit hepatocellular carcinoma cell growth, migration, and invasion but through different signaling pathways. " 52 circRNA diagnostic biomarker circ-ITCH human "tissue,cell" glioma H original research 29887952 Identification of the tumor-suppressive function of circular RNA ITCH in glioma cells through sponging miR-214 and promoting linear ITCH expression 53 circRNA diagnostic biomarker ciRS-7 human uncertain cervical cancer uncertain review 30787966 Biological functions of circular RNAs and their roles in occurrence of reproduction and gynecological diseases 54 circRNA diagnostic biomarker has-circ-0001445 human tissue bladder cancer H original research 30782157 Circular RNA cTFRC acts as the sponge of MicroRNA-107 to promote bladder carcinoma progression. 55 circRNA diagnostic biomarker F-circEA-2a human plasma lung cancer non-small cell lung cancer uncertain original research 30236141 Circular RNA F-circEA-2a derived from EML4-ALK fusion gene promotes cell migration and invasion in non-small cell lung cancer 56 circRNA diagnostic biomarker "hsa_circ_0000172,hsa_circ_0002495" human tissue bladder cancer H original research 29558461 Molecular and Bioinformatics Analyses Identify 7 Circular RNAs Involved in Regulation of Oncogenic Transformation and Cell Proliferation in Human Bladder Cancer. 57 circRNA diagnostic biomarker hsa_circ_0001946 human "tissue,cell" lung cancer non-small cell lung cancer H original research 30841451 CircRNA has_circ_0001946 promotes cell growth in lung adenocarcinoma by regulating miR-135a-5p/SIRT1 axis and activating Wnt/¦Â-catenin signaling pathway. 58 circRNA diagnostic biomarker hsa_circ_002059 human tissue uncertain uncertain review 29034621 Circular RNAs and their roles in tumorigenesis 59 circRNA diagnostic biomarker hsa_circ_0000096 human "tissue,cell" gastric cancer L original research 28081541 Circular RNA 0000096 affects cell growth and migration in gastric cancer 60 circRNA diagnostic biomarker hsa_circ_00001649 human serum gastric cancer L original research 28167847 Decreased Expression of Hsa_circ_00001649 in Gastric Cancer and Its Clinical Significance 61 circRNA diagnostic biomarker hsa_circ_0000181 human "tissue,plasma" gastric cancer L original research 28940688 Clinical values of circular RNA 0000181 in the screening of gastric cancer. 62 circRNA diagnostic biomarker hsa_circ_0000190 human "tissue,plasma" uncertain Multiple cancers L review 28535767 CircRNA: functions and properties of a novel potential biomarker for cancer. 63 circRNA diagnostic biomarker hsa_circ_0000190 human uncertain digestive system cancer L original research 29428945 Meta-Analysis of the diagnostic Accuracy of Circular RNAs in Digestive System Malignancy. 64 circRNA diagnostic biomarker hsa_circ_0000190 human "tissue,plasma" gastric cancer L original research 28130019 Using circular RNA hsa_circ_0000190 as a new biomarker in the diagnosis of gastric cancer 65 circRNA diagnostic biomarker hsa_circ_0000190 human tissue lung cancer L review 30403899 Research progress of circular RNAs in lung cancer 66 circRNA diagnostic biomarker hsa_circ_0000285 human "serum,tissue,cell" bladder cancer L original research 30509102 Downregulation of hsa_circ_0000285 serves as a prognostic biomarker for bladder cancer and is involved in cisplatin resistance. 67 circRNA diagnostic biomarker hsa_circ_0000337 human "tissue,cell" esophageal cancer esophageal squamous cell cancer H original research 30881124 "Upregulated circ RNA hsa_circ_0000337 promotes cell proliferation, migration, and invasion of esophageal squamous cell carcinoma." 68 circRNA diagnostic biomarker hsa_circ_0000467 human "tissue,cell,plasma" gastric cancer H original research 30461077 Hsa_circ_0000467 promotes cancer progression and serves as a diagnostic and prognostic biomarker for gastric cancer 69 circRNA diagnostic biomarker hsa_circ_0000520 human "tissue,cell,plasma" gastric cancer L original research 29103021 "Hsa_circ_0000520, a potential new circular RNA biomarker, is involved in gastric carcinoma" 70 circRNA diagnostic biomarker hsa_circ_0000567 human "tissue,cell " colorectal cancer L original research 29333615 Circular RNA hsa_circ_0000567 can be used as a promising diagnostic biomarker for human colorectal cancer 71 circRNA diagnostic biomarker hsa_circ_0000673 human "tissue,cell,plasma" gastric cancer L original research 30061181 Hsa_circ_0000673 is down-regulated in gastric cancer and inhibits the proliferation and invasion of tumor cells by targetting miR-532-5p 72 circRNA diagnostic biomarker hsa_circ_0000711 human "tissue,cell " colorectal cancer L original research 30147374 The expression profile and clinical application potential of hsa_circ_0000711 colorectal cancer 73 circRNA diagnostic biomarker hsa_circ_0000745 human "tissue,plasma" gastric cancer L original research 28974900 Circular RNA hsa_circ_0000745 may serve as a diagnostic marker for gastric cancer. 74 circRNA diagnostic biomarker hsa_circ_0000826 human tissue colorectal cancer L original research 30320923 Analysis of differentially expressed circular RNAs for the identification of a coexpression RNA network and signature in colorectal cancer. 75 circRNA diagnostic biomarker hsa_circ_0000885 human "tissue,serum" osteosarcoma H original research 30802235 Circular RNA hsa_circ_0000885 Levels are Increased in Tissue and Serum Samples from Patients with Osteosarcoma. 76 circRNA diagnostic biomarker "hsa_circ_0001017,hsa_circ_0061276" human "tissue,plasma" gastric cancer L original research 29098316 Plasma circular RNA profiling of patients with gastric cancer and their droplet digital RT-PCR detection 77 circRNA diagnostic biomarker hsa_circ_0001445 human "tissue,plasma" hepatocellular cancer L original research 29785229 The Circular RNA hsa_circ_0001445 Regulates the Proliferation and Migration of Hepatocellular Carcinoma and May Serve as a Diagnostic Biomarker. 78 circRNA diagnostic biomarker "hsa_circ_0001445,hsa_circ_0091579" human tissue hepatocellular cancer H(hsa_circ_0091579) original research 30453307 Circular RNA Hsa_Circ_0091579 Serves as a Diagnostic and Prognostic Marker forHepatocellular Carcinoma 79 circRNA diagnostic biomarker hsa_circ_0001451 human tissue renal cancer clear cell renal cell cancer L original research 30271486 The effect of Hsa_circ_0001451 in clear cell renal cell carcinoma cells and its relationship with clinicopathological features 80 circRNA diagnostic biomarker hsa_circ_0001649 human tissue uncertain Multiple cancers L review 29387208 Circular RNAs function as competing endogenous RNAs in multiple types of cancer. 81 circRNA diagnostic biomarker hsa_circ_0001649 human "tissue,serum" colorectal cancer L original research 29421663 Hsa_circ_0001649: A circular RNA and potential novel biomarker for colorectal cancer. 82 circRNA diagnostic biomarker "hsa_circ_0001649,hsa_circ_0005075" human tissue hepatocellular cancer "H(hsa_circ_0005075),L(hsa_circ_0001649)" original research 29387227 Screening of up and downregulation of circRNAs in HBV-related hepatocellular carcinoma by microarray. 83 circRNA diagnostic biomarker hsa_circ_0001785 human plasma breast cancer H original research 29045858 Circulating circular RNA hsa_circ_0001785 acts as a diagnostic biomarker for breast cancer detection 84 circRNA diagnostic biomarker hsa_circ_0001895 human tissue gastric cancer L original research 28443463 Decreased expression of hsa_circ_0001895 in human gastric cancer and its clinical significances 85 circRNA diagnostic biomarker "hsa_circ_0001946,hsa_circ_0043603" human "tissue,plasma" esophageal cancer esophageal squamous cell cancer H(hsa_circ_0001946) original research 30674324 Circular RNA profiling and its potential for esophageal squamous cell cancer diagnosis and prognosis 86 circRNA diagnostic biomarker hsa_circ_0003159 human tissue gastric cancer L original research 28618205 Reduced expression of circRNA hsa_circ_0003159 in gastric cancer and its clinical significance 87 circRNA diagnostic biomarker hsa_circ_0004018 human tissue hepatocellular cancer L review 28833094 Progress and prospects of circular RNAs in Hepatocellular carcinoma: Novel insights into their function 88 circRNA diagnostic biomarker hsa_circ_0004277 human tissue leukemia acute myeloid leukemia L original research 28282919 Characterization of hsa_circ_0004277 as a New Biomarker for Acute MyeloidLeukemia via Circular RNA Profile and Bioinformatics Analysis 89 circRNA diagnostic biomarker hsa_circ_0004277 human uncertain uncertain L original research 29393503 "Circular RNAs: Characteristics, function, and role in human cancer" 90 circRNA diagnostic biomarker hsa_circ_0004277 human tissue leukemia L review 30842885 Circular RNAs in leukemia. 91 circRNA diagnostic biomarker hsa_circ_0005033 human tissue laryngeal cancer laryngeal squamous cell cancer H original research 29949786 Whole-Transcriptome Analysis of CD133+CD144+ Cancer Stem Cells Derived from Human Laryngeal Squamous Cell Carcinoma Cells. 92 circRNA diagnostic biomarker hsa_circ_0005075 human tissue hepatocellular cancer H original research 27258521 "Comprehensive Circular RNA Profiling reveals That hsa_circ_0005075, a NewCircular RNA Biomarker, Is Involved in Hepatocellular Crcinoma Development." 93 circRNA diagnostic biomarker hsa_circ_0005075 human tissue uncertain Multiple cancers H review 29096676 Circular RNAs: emerging cancer biomarkers and targets. 94 circRNA diagnostic biomarker "hsa_circ_0005320,hsa_circ_0067531,hsa_circ_0008042,hsa_circ_0000869,hsa_circ_0000853" human tissue melanoma "H(hsa_circ_0005320,hsa_circ_0067531,hsa_circ_0008042 ),L(hsa_circ_0000869,hsa_circ_0000853 )" original research 30323971 Altered expression pattern of circular RNAs in metastatic oral mucosal melanoma 95 circRNA diagnostic biomarker hsa_circ_0005836 human uncertain lung cancer L original research 28846924 The circular RNA of peripheral blood mononuclear cells: Hsa_circ_0005836 as a new diagnostic biomarker and therapeutic target of active pulmonary tuberculosis 96 circRNA diagnostic biomarker hsa_circ_0005962 human "tissue,cell,plasma" lung cancer non-small cell lung cancer H original research 30777071 A two-circular RNA signature as a noninvasive diagnostic biomarker for lung adenocarcinoma 97 circRNA diagnostic biomarker hsa_circ_0005986 human "tissue,cell" hepatocellular cancer L original research 28410211 Hsa_circ_0005986 inhibits carcinogenesis by acting as a miR-129-5p sponge and is used as a novel biomarker for hepatocellular carcinoma. 98 circRNA diagnostic biomarker hsa_circ_0006633 human plasma gastric cancer L original research 28656881 Low expression of hsa_circ_0006633 in human gastric cancer and its clinical significances 99 circRNA diagnostic biomarker "hsa_circ_0008287,hsa_circ_0005027" human "tissue,cell,serum" hypopharyngeal cancer L original research 30365065 CircRNA-associated ceRNA network reveals ErbB and Hippo signaling pathways in hypopharyngeal cancer. 100 circRNA diagnostic biomarker hsa_circ_001242 human "tisssue,cell" oral cancer oral squamous cell carcinoma L original research 30069275 Clinical Significance of the Decreased Expression of hsa_circ_001242 in Oral Squamous Cell Carcinoma. 101 circRNA diagnostic biomarker hsa_circ_0013958 human plasma lung cancer non-small cell lung cancer H original research 28685964 hsa_circ_0013958: a circular RNA and potential novel biomarker for lung adenocarcinoma. 102 circRNA diagnostic biomarker hsa_circ_0013958 human "tisssue,cell" lung cancer H original research 30711537 CircRNAs and lung cancer: Biomarkers and master regulators. 103 circRNA diagnostic biomarker hsa_circ_0014130 human tissue lung cancer non-small cell lung cancer H original research 29440731 Microarray profile of circular RNAs identifies hsa_circ_0014130 as a new circular RNA biomarker in non-small cell lung cancer 104 circRNA diagnostic biomarker hsa_circ_001988 human tissue colorectal cancer L original research 26884878 Decreased expression of hsa_circ_001988 in colorectal cancer and its clinicalsignificances 105 circRNA diagnostic biomarker hsa_circ_002059 human "tisssue,plasma" gastric cancer L original research 25689795 Using circular RNA as a novel type of biomarker in the screening of gastric cancer 106 circRNA diagnostic biomarker hsa_circ_002059 human tissue "gastric cancer,colorectal cancer" L review 26052092 Circular RNA: A new star of noncoding RNAs. 107 circRNA diagnostic biomarker hsa_circ_002059 human tissue uncertain L review 28969093 Circular RNAs: A novel type of biomarker and genetic tools in cancer. 108 circRNA diagnostic biomarker hsa_circ_002059 human tissue gastrointestinal cancer "L(hsa_circ_001988,hsa_circ_002059)" review 29344130 Potential functions and implications of circular RNA in gastrointestinal cancer. 109 circRNA diagnostic biomarker hsa_circ_002059 human cell esophageal cancer esophageal squamous cell carcinoma L original research 29218114 Comparative transcriptome analysis of the global circular RNAs expression profiles between SHEE and SHEEC cell lines. 110 circRNA diagnostic biomarker hsa_circ_002059 human uncertain uncertain L(hsa_circ_002059) review 26874353 The understanding of circular RNAs as special triggers in carcinogenesis 111 circRNA diagnostic biomarker "hsa_circ_002059,hsa_circ_0001649" human "saliva,blood" uncertain H(hsa_circ_00205) review 27429839 Circular RNAs as potential biomarkers for cancer diagnosis and therapy 112 circRNA diagnostic biomarker "hsa_circ_002059,hsa_circ_0067531" human uncertain oral cancer H(CircRNA-100290) review 29206174 A Looking-Glass of Non-Coding RNAs in Oral Cancer 113 circRNA diagnostic biomarker hsa_circ_0021001 human blood intracranial aneurysm L original research 29291016 Circular RNA hsa_circ_0021001 in peripheral blood: a potential novel biomarker inthe screening of intracranial aneurysm 114 circRNA diagnostic biomarker hsa_circ_0055538 human "tisssue,cell" oral cancer oral squamous cell carcinoma L original research 30857544 Circular RNA hsa_circ_0055538 regulates the malignant biological behavior of oral squamous cell carcinoma through the p53/Bcl-2/caspase signaling pathway. 115 circRNA diagnostic biomarker hsa_circ_0068669 human "tisssue,cell" hepatocellular cancer L original research 29785842 Circular RNA 0068669 as a new biomarker for hepatocellular carcinoma metastasis 116 circRNA diagnostic biomarker hsa_circ_0074362 human "tisssue,cell" gastric cancer L original research 29240459 Downregulated expression of hsa_circ_0074362 in gastric cancer and its potential diagnostic values. 117 circRNA diagnostic biomarker hsa_circ_0078602 human tissue hepatocellular cancer L original research 30675276 Circular RNA hsa_circ_0078602 may have potential as a prognostic biomarker for patients with hepatocellular carcinoma 118 circRNA diagnostic biomarker hsa_circ_0081001 human "tissue,cell,serum" osteosarcoma H original research 30263004 A novel circulating hsa_circ_0081001 act as a potential biomarker for diagnosis and prognosis of osteosarcoma 119 circRNA diagnostic biomarker hsa_circ_0128298 human tissue hepatocellular cancer H original research 29849467 Screening differential circular RNA expression profiles reveal that hsa_circ_0128298 is a biomarker in the diagnosis and prognosis of hepatocellular carcinoma 120 circRNA diagnostic biomarker hsa_circ_0137287 human tissue thyroid cancer papillary thyroid cancer L original research 29790216 Decreased expression of hsa_circ_0137287 predicts aggressive clinicopathologic characteristics in papillary thyroid carcinoma. 121 circRNA diagnostic biomarker "hsa_circ_047771,hsa_circ_007148" human tissue thyroid cancer papillary thyroid cancer "H(hsa_circRNA_007148),L(hsa_circRNA_047771)" original research 30123704 Profile and clinical implication of circular RNAs in human papillary thyroid carcinoma. 122 circRNA diagnostic biomarker "hsa_circ_100855,hsa_circ_104912" human tissue uncertain "L(hsa_circ_0001649,hsa_circ_002059)" review 28839467 Circular RNAs: Regulators of Cancer-Related Signaling Pathways and Potential diagnostic Biomarkers for Human Cancers. 123 circRNA diagnostic biomarker hsa_circ_102347 human uncertain hepatocellular cancer primary hepatic carcinoma. L original research 29609527 The differentially expressed circular ribonucleic acids of primary hepatic carcinoma following liver transplantation as new diagnostic biomarkers for primary hepatic carcinoma. 124 circRNA diagnostic biomarker hsa_circ_102958 human tissue gastric cancer H original research 30689557 Circular RNA hsa_circRNA_102958 may serve as a diagnostic marker for gastric cancer 125 circRNA diagnostic biomarker "hsa_circ_104912,hsa_circ_100855" human tissue laryngeal cancer laryngeal squamous cell cancer "H(hsa_circRNA_100855),L(hsa_circRNA_104912)" original research 27158380 Circular RNA: a novel biomarker for progressive laryngeal cancer