No. Biomarker_type Function_type Biomarker_symbol Species Tissue_or_sample Cancer_type Cancer_subtype Expression(Adverse risk) Reference type PMID Article_title 1 lncRNA diagnostic biomarker "MALAT1,PCAT1,CPS1-IT1" human "tissue,cell,plamsa" cholangio cancer H(MALAT1) review 30888066 Functions and roles of long noncoding RNA in cholangiocarcinoma. 2 lncRNA diagnostic biomarker MALAT1 human "tissue,cell,plamsa" hepatocellular cancer H original research 30886644 PAMAM/polyhedral nanogold-modified probes with DNAase catalysis for the amperometric electrochemical detection of metastasis-associated lung adenocarcinoma transcript 1 3 lncRNA diagnostic biomarker lnc-FAM84B-15 human uncertain cholangio cancer H original research 30881042 lncRNAs as potential molecular biomarkers in the clinicopathology and prognosis of cholangiocarcinoma: a systematic review and meta-analysis 4 lncRNA diagnostic biomarker KAT7 human tissue colorectal cancer L original research 30858757 A novel long non-coding RNA-KAT7 is low expressed in colorectal cancer and acts as a tumor suppressor. 5 lncRNA diagnostic biomarker lnc-NEFM-1 human serum lung cancer non-small-cell lung cancer L original research 30854054 Long non-coding RNA-NEF targets glucose transportation to inhibit the proliferation of non-small-cell lung cancer cells. 6 lncRNA diagnostic biomarker "LINC01149,EPB41L4A-AS1" human tissue colorectal cancer uncertain original research 30854042 Identification of prognostic biomarkers in colorectal cancer using a long non?coding RNA?mediated competitive endogenous RNA network 7 lncRNA diagnostic biomarker lnc-TINCR-1 human tissue colorectal cancer H original research 30853664 SP1-induced lncRNA TINCR overexpression contributes to colorectal cancer progression by sponging miR-7-5p. 8 lncRNA diagnostic biomarker SNHG1 human "tissue,cell" uncertain Multiple cancers H review 30849309 Long non-coding SNHG1 in cancer. 9 lncRNA diagnostic biomarker SNHG20 human tissue ovarian cancer epithelial ovarian cancer H original research 30846486 LncRNA SNHG20 predicts a poor prognosis and promotes cell progression in epithelial ovarian cancer. 10 lncRNA diagnostic biomarker SNHG6 human tissue breast cancer H original research 30826970 SNHG6 is upregulated in primary breast cancers and promotes cell cycle progression in breast cancer-derived cell lines. 11 lncRNA diagnostic biomarker CASC9 human tissue breast cancer H original research 30816435 lncRNA CASC9 positively regulates CHK1 to promote breast cancer cellproliferation and survival through sponging the miR?195/497 cluster. 12 lncRNA diagnostic biomarker "H19,UCA1" human blood ureteral cell cancer H original research 30813594 Impact of Long Non-Coding RNA HOTAIR Genetic Variants on the Susceptibility and Clinicopathologic Characteristics of Patients with Urothelial Cell Carcinoma 13 lncRNA diagnostic biomarker "MALAT1,H19,BANCR,HOTAIR" human uncertain thyroid cancer "H(MALAT1,H19,BANCR,HOTAIR)" original research 30799425 "Long Non-Coding RNAs in Thyroid Cancer: Implications for Pathogenesis, Diagnosis, and Therapy." 14 lncRNA diagnostic biomarker MT1JP human "tissue,cell" breast cancer L original research 30787983 MT1JP inhibits tumorigenesis and enhances cisplatin sensitivity of breast cancer cells through competitively binding to miR-24-3p. 15 lncRNA diagnostic biomarker lnc-PDZD7-3 human tissue hepatocellular cancer H original research 30786928 Lnc-PDZD7 contributes to stemness properties and chemosensitivity in hepatocellular carcinoma through EZH2-mediated ATOH8 transcriptional repression 16 lncRNA diagnostic biomarker "GAS5,lnc-DLK1-35,FER1L4,LINC00672,lnc-MGAT1-4,BANCR,NEAT1,MALAT1,H19,LINC-RoR,TUG1,lnc-DAAM2-9,PCGEM1" human tissue uterine cancer endometrial cancer "H(MALAT1,H19,GAS5,TUG1)" review 30781521 Exploring lncRNA-Mediated Regulatory Networks in Endometrial cancer Cells and the Tumor Microenvironment: Advances and Challenges. 17 lncRNA diagnostic biomarker ZEB1-AS1 human "tissue,cell" gastric cancer "H(qPCR,ZEB1-AS1),L(miR-149-3p)" original research 30774556 ZEB1-AS1 initiates a miRNA-mediated ceRNA network to facilitate gastric cancer progression. 18 lncRNA diagnostic biomarker LINC00958 human serum gastric cancer H original research 30763257 Evaluating the diagnostic and prognostic value of serum long non-coding RNA CTC-497E21.4 in gastric cancer 19 lncRNA diagnostic biomarker "BCAR4,lnc-MGAT1-4,lnc-FOXB2-9,lnc-ADA-3,ZFAS1" human serum;uncertain;uncertain;uncertain;tissue uncertain H(lnc-FOXB2-9) review 30739532 The functional roles of exosomes-derived long non-coding RNA in human cancer. 20 lncRNA diagnostic biomarker TUG1 human tissue melanoma H original research 30720136 Long non-coding RNA TUG1 recruits miR?29c?3p from its target gene RGS1 to promoteproliferation and metastasis of melanoma cells. 21 lncRNA diagnostic biomarker GIHCG human serum cervical cancer H original research 30719165 Long noncoding RNA GIHCG functions as an oncogene and serves as a serum diagnostic biomarker for cervical cancer. 22 lncRNA diagnostic biomarker "lnc-MGAT1-4,GNAT1-1" human uncertain;serum colorectal cancer H original research 30719158 Long Noncoding RNAs Serve as Potential diagnostic Biomarkers for Colorectal cancer. 23 lncRNA diagnostic biomarker lnc-FAM84B-15 human plasma colon cancer H review 30693526 Colon cancer-Associated Transcripts 1 and 2: Roles and functions in human cancers. 24 lncRNA diagnostic biomarker LINC00665 human tissue lung cancer non-small-cell lung cancer H original research 30692511 Long non-coding RNA linc00665 promotes lung adenocarcinoma progression andfunctions as ceRNA to regulate AKR1B10-ERK signaling by sponging miR-98. 25 lncRNA diagnostic biomarker LINC00086 human blood gastric cancer "H(miR-214),L(LINC00086)" original research 30689553 Potential diagnostic and prognostic value of plasma long noncoding RNA LINC00086 and miR-214 expression in gastric cancer. 26 lncRNA diagnostic biomarker CASC9 human tissue oral cancer oral squamous cell carcinoma H original research 30674868 Increased expression of lncRNA CASC9 promotes tumor progression by suppressing autophagy-mediated cell apoptosis via the AKT/mTOR pathway in oral squamous cell carcinoma. 27 lncRNA diagnostic biomarker lnc-NEFM-1 human serum gastric cancer L original research 30664208 LncRNA?NEF is involved the regulation of gastric carcinoma cell proliferation by targeting RUNX1. 28 lncRNA diagnostic biomarker "MALAT1,UCA1" human uncertain bladder cancer H original research 30654976 "Measurement of Urinary Level of a Specific Competing endogenous RNA network (FOS and RCAN mRNA/ miR-324-5p, miR-4738-3p, /lncRNA miR-497-HG) Enables diagnosis of Bladder Cancer." 29 lncRNA diagnostic biomarker "91H,MALAT1,combine(lnc-DLK1-35,SNHG16,MALAT1),ZFAS1" human plasma;serum;urine;uncertain uncertain Multiple cancers H review 30649349 Exosomal lncRNAs and cancer: connecting the missing links. 30 lncRNA diagnostic biomarker "combine(ADAMTS9-AS2,PVT1)" human tissue esophageal cancer H original research 30643460 Robust analysis of novel mRNA-lncRNA cross talk based on ceRNA hypothesis uncovers carcinogenic mechanism and promotes diagnostic accuracy in esophageal cancer. 31 lncRNA diagnostic biomarker FOXD2-AS1 human tissue breast cancer H original research 30628646 Long non?coding RNA FOXD2?AS1/miR?150?5p/PFN2 axis regulates breast cancer malignancy and tumorigenesis. 32 lncRNA diagnostic biomarker SNHG6 human cell colorectal cancer L original research 30626446 lncRNA SNHG6 regulates EZH2 expression by sponging miR-26a/b and miR-214 in colorectal cancer 33 lncRNA diagnostic biomarker LINC00461 human tissue breast cancer H original research 30623482 LINC00461 promotes cell migration and invasion in breast cancer throughmiR-30a-5p/integrin β3 axis. 34 lncRNA diagnostic biomarker DANCR human tissue lung cancer non-small cell lung cancer H original research 30613152 Long non-coding RNA DANCR promotes the progression of non-small-cell lung cancer by inhibiting p21 expression. 35 lncRNA diagnostic biomarker RP11-397A15.4 human tissue gastric cancer H original research 30610039 Increased Expression of Lncrna RP11-397A15.4 in Gastric Cancer and Its Clinical Significance. 36 lncRNA diagnostic biomarker "FAM49B-AS,lnc-IGLL1-1,CTDHUT" human plasma gastric cancer H original research 30603909 Genome-wide long non-coding RNAs identified a panel of novel plasma biomarkers for gastric cancer diagnosis. 37 lncRNA diagnostic biomarker TUG1 human tissue pancreatic cancer L original research 30595764 "Long Noncoding RNA TUG1/miR-29c Axis Affects Cell Proliferation, Invasion, andMigration in Human Pancreatic Cancer." 38 lncRNA diagnostic biomarker TUG1 human uncertain uncertain H review 30590378 Taurine-upregulated gene 1 contributes to cancers through sponging microRNA. 39 lncRNA diagnostic biomarker AFAP1-AS1 human tissue colon cancer H original research 30588252 High Expression of lncRNA AFAP1-AS1 Promotes the Progression of Colon Cancer and Predicts Poor Prognosis. 40 lncRNA diagnostic biomarker LINC00460 human tissue breast cancer invasive breast cancer H original research 30588106 The construction and analysis of ceRNA networks in invasive breast cancer: a study based on The Cancer Genome Atlas. 41 lncRNA diagnostic biomarker MALAT1 human uncertain uncertain H review 30584369 MALAT1: a potential biomarker in cancer. 42 lncRNA diagnostic biomarker H19 human serum bladder cancer H original research 30576305 Determination of Serum Exosomal H19 as a Noninvasive Biomarker for Bladder Cancer Diagnosis and Prognosis. 43 lncRNA diagnostic biomarker PCAT6 human tissue colon cancer H original research 30569799 Long noncoding RNA PCAT6 inhibits colon cancer cell apoptosis by regulatinganti-apoptotic protein ARC expression via EZH2. 44 lncRNA diagnostic biomarker "UCA1-201,UCA1-203,MALAT1,LINC00355" human urine bladder cancer "H(LINC00355,UCA1-203,MALAT1),L(UCA1-201)" original research 30568497 Urinary exosomal expression of long non-coding RNAs as diagnostic marker inbladder cancer. 45 lncRNA diagnostic biomarker "combine(lnc-BMP6-106,CYTOR)" human uncertain hepatocellular cancer "H(MALAT1,HULC,HOTAIR,H19),L(MEG-3)" review 30564069 lncRNA involvement in hepatocellular carcinoma metastasis and prognosis. 46 lncRNA diagnostic biomarker "combine(LNCV6_116109,LNCV6_98390,LNCV6_38772,LNCV_108266,LNCV6_84003,LNCV6_98602)" human plasma colorectal cancer H original research 30562751 plasma Exosomal Long Non-Coding RNAs Serve as Biomarkers for Early Detection of Colorectal Cancer. 47 lncRNA diagnostic biomarker MALAT1 human uncertain uncertain H original research 30561226 Long noncoding RNA MALAT1 acts as a potential biomarker in cancer diagnosis and detection: a meta-analysis. 48 lncRNA diagnostic biomarker lnc-SKA2-1 human uncertain gastric cancer H original research 30560474 Prognostic and clinicopathological significance of long noncoding RNA CTD-2510F5.4 in gastric cancer. 49 lncRNA diagnostic biomarker lnc-FOXB2-9 human uncertain uncertain prostate cancer H review 30549380 Long non-coding RNAs in cancer: Another layer of complexity. 50 lncRNA diagnostic biomarker "HOTAIR,H19,lnc-DLK1-35" human uncertain head and neck cancer head and neck squamous cell carcinoma H original research 30548328 Identification of 4‐lncRNA prognostic signature in head and neck squamous cell carcinoma 51 lncRNA diagnostic biomarker lnc-ALPK1-1 human tissue hepatocellular cancer L original research 30546827 Decreased long intergenic noncoding RNA P7 predicts unfavorable prognosis and promotes tumor proliferation via the modulation of the STAT1-MAPK pathway in hepatocellular carcinoma 52 lncRNA diagnostic biomarker SNHG20 human serum nasopharyngeal cancer H original research 30546404 Long non-coding RNA SNHG20 promotes nasopharyngeal carcinoma cell migration and invasion by upregulating TGF-β1. 53 lncRNA diagnostic biomarker lnc-LRRC47-78 human "tissue,cell" lung cancer non-small cell lung cancer H original research 30541897 LncRNA TP73-AS1 promoted the progression of lung adenocarcinoma via PI3K/AKT pathway. 54 lncRNA diagnostic biomarker LINC00265 human "bone marrow,serum" leukemia acute myeloid leukemia H original research 30536332 Long noncoding RNA LINC00265 predicts the prognosis of acute myeloid leukemiapatients and functions as a promoter by activating PI3K-AKT pathway 55 lncRNA diagnostic biomarker lnc-FAM84B-15 human uncertain uncertain H review 30535444 Pivotal prognostic and diagnostic role of the long non?coding RNA colon cancer?associated transcript 1 expression in human cancer (Review). 56 lncRNA diagnostic biomarker "AA174084,GAPLINC,PCAT1" human tissue esophageal cancer H review 30533569 LONG-NONCODING RNAs in gastroesophageal cancers. 57 lncRNA diagnostic biomarker PAC3 human uncertain lung cancer non-small cell lung cancer H review 30519046 Potential clinical application of lncRNAs in non-small cell lung cancer. 58 lncRNA diagnostic biomarker RUNX1-IT1 human blood colorectal cancer L original research 30499136 Long non-coding RNA RUNX1-IT1 plays a tumour-suppressive role in colorectal cancer by inhibiting cell proliferation and migration. 59 lncRNA diagnostic biomarker "RPL5,RPL10" human tissue teratoid/rhabdoid tumor H original research 30479569 Identification of RPL5 and RPL10 as novel diagnostic biomarkers of Atypical teratoid/rhabdoid tumors. 60 lncRNA diagnostic biomarker GASL1 human serum lung cancer non-small cell lung cancer L original research 30468472 LncRNA GASL1 inhibits tumor growth of non-small cell lung cancer by inactivating TGF-β pathway. 61 lncRNA diagnostic biomarker "combine(PCAT1,UBC1,SNHG16)" human serum bladder cancer H original research 30467945 Evaluation of serum exosomal LncRNA-based biomarker panel for diagnosis and recurrence prediction of bladder cancer. 62 lncRNA diagnostic biomarker lnc-IRX3-80 human uncertain pan-cancer H original research 30463803 "The diagnostic and prognostic significance of long non-coding RNA CRNDE in pan-cancer based on TCGA, GEO and comprehensive meta-analysis." 63 lncRNA diagnostic biomarker "HOTAIR,CDKN2B-AS1,H19" human uncertain uncertain "H(HOTAIR,H19)" review 30461116 Long noncoding RNA expression profiling in cancer: Challenges and opportunities. 64 lncRNA diagnostic biomarker MRPL39 human "tissue,cell" gastric cancer L original research 30452299 Long Noncoding RNA MRPL39 Inhibits Gastric Cancer Proliferation and Progression by Directly Targeting miR-130. 65 lncRNA diagnostic biomarker DANCR human cell bladder cancer H original research 30419948 Long non-coding RNA DANCR promotes malignant phenotypes of bladder cancer cells by modulating the miR-149/MSI2 axis as a ceRNA. 66 lncRNA diagnostic biomarker "PCAT6,HOTAIR,NEAT1,AFAP1-AS1,MALAT1,lnc-USP6NL-7,lnc-FAM84B-15,XIST,CASC2,GAS6-AS1,CDKN2B-AS1,lnc-FGF1-9" human uncertain lung cancer H review 30417217 Multidimensional communication of microRNAs and long non-coding RNAs in lung cancer. 67 lncRNA diagnostic biomarker "combine(lnc-RC3H1-1,XLOC014172,LOC149086,CYTOR,lnc-RC3H1-1,XLOC014172,lnc-BMP6-106,CYTOR,uc001ncr,AX800134,PVT1,MIR7-3HG,lnc-RC3H1-1,XLOC-014172,LOC149086,UCA1,WRAP53,AF085935,uc003wbd,PVT1,MIR7-3HG,PANDAR,lnc-FGF1-9,uc001ncr,AX800134,CYTOR,lnc-BMP6-106)" human "serum,plasma;uncertain" hepatocellular cancer "H(UCA1,PVT1,PANDAR)" original research 30410873 diagnostic Value of lncRNAs as Biomarker in Hepatocellular Carcinoma: An Updated Meta-Analysis 68 lncRNA diagnostic biomarker "AC017078.1,lnc-GPR132-1" human serum cervical cancer uncertain original research 30410863 Identification of reference genes for circulating long noncoding RNA analysis in serum of cervical cancer patients. 69 lncRNA diagnostic biomarker "PVT1,GLIS2-AS1" human tissue thyroid cancer parathyroid cancer H original research 30403657 Profiling analysis of long non-coding RNA and mRNA in parathyroid carcinoma. 70 lncRNA diagnostic biomarker lnc-NEFM-1 human serum esophageal cancer esophageal squamous-cell carcinoma L original research 30402846 "LncRNA-NEF inhibits proliferation, migration and invasion of esophageal squamous-cell carcinoma cells by inactivating wnt/β-catenin pathway." 71 lncRNA diagnostic biomarker lnc-BMP6-106 human uncertain uncertain uncertain review 30386629 Long non-coding RNA: its evolutionary relics and biological implications in mammals: a review 72 lncRNA diagnostic biomarker lnc-C19orf57-6 human tissue nasopharyngeal cancer H original research 30380023 Long non-coding RNA LOC284454 promotes migration and invasion of nasopharyngeal carcinoma via modulating the Rho/Rac signaling pathway. 73 lncRNA diagnostic biomarker LINC0096 human cell renal cancer L original research 30367453 LINC00961 restrains cancer progression via modulating epithelial-mesenchymal transition in renal cell carcinoma. 74 lncRNA diagnostic biomarker ARA human tissue "breast cancer,hepatocellular cancer" H original research 30367404 "ARA lncRNA, is upregulated in liver and breast tumor tissues." 75 lncRNA diagnostic biomarker LINC02487 human tissue oral cancer oral squamous cell carcinoma L original research 30364063 Long Noncoding RNA LOC441178 Reduces the Invasion and Migration of Squamous Carcinoma Cells by Targeting ROCK1. 76 lncRNA diagnostic biomarker lnc-THEMIS-2 human serum mesothelioma pleural mesothelioma H(MALAT1) original research 30362153 "Clinical significance of serum DRAM1 mRNA, ARSA mRNA, hsa-miR-2053 and lncRNA-RP1-86D1.3 axis expression in malignant pleural mesothelioma." 77 lncRNA diagnostic biomarker "HOXA11-AS,LINC00964,MALAT1" human plasma head and neck cancer head and neck squamous cell carcinoma H original research 30355951 Circulating Long Noncoding RNAs as Biomarkers for Predicting Head and Neck Squamous Cell Carcinoma. 78 lncRNA diagnostic biomarker NORAD human tissue，plamsa colorectal cancer H original research 30349308 Overexpression of long noncoding RNA NORAD in colorectal cancer associates with tumor progression. 79 lncRNA diagnostic biomarker "FENDRR,LINC00312" human uncertain lung cancer non-small cell lung cancer uncertain original research 30344725 Identification of ceRNA network based on a RNA-seq shows prognostic lncRNA biomarkers in human lung adenocarcinoma. 80 lncRNA diagnostic biomarker lnc-DLK1-35 human tissue osteosarcoma uncertain original research 30324678 Long noncoding RNA MEG3 play an important role in osteosarcoma development through sponging microRNAs. 81 lncRNA diagnostic biomarker UCA1 human uncertain bladder cancer H original research 30323619 LncRNA as a diagnostic and prognostic biomarker in bladder cancer: a systematic review and meta-analysis. 82 lncRNA diagnostic biomarker RP11-555H23.1 human tissue gastric cancer " H(RP11-605F14.2,TBC1D3P5,BC130595,LINC00475,RP11-19P22.6,BC080653,XLOC_004923,AFAP1-AS1,EPB49,RP11-296I10.3),L(TUG1,RP11-555H23.1,RP1-257I20.13,UGP2,GCSHP3,XLOC_000889)" original research 30320481 Global expression profiling of metabolic pathway-related lncRNAs in human gastric cancer and the identification of RP11-555H23.1 as a new diagnostic biomarker. 83 lncRNA diagnostic biomarker FLVCR1-DT human "tissue,cell" lung cancer non-small cell lung cancer H original research 30309647 Long non-coding RNA FLVCR1-AS1 contributes to the proliferation and invasion of lung cancer by sponging miR-573 to upregulate the expression of E2F transcription factor 3. 84 lncRNA diagnostic biomarker "combine(H19,C3P1,lnc-LRRC72-3,PVT1,LPAL2)" human tissue cholangio cancer "H(H19,PVT1)" original research 30305026 Global identification and characterization of lncRNAs that control inflammation in malignant cholangiocytes. 85 lncRNA diagnostic biomarker HAGLR human uncertain uncertain Multiple cancers H review 30290157 Long non-coding RNA HOXD-AS1 in cancer. 86 lncRNA diagnostic biomarker PTENP1 human plasma bladder cancer L original research 30285771 Exosome-transmitted long non-coding RNA PTENP1 suppresses bladder cancer progression. 87 lncRNA diagnostic biomarker PRAL human tissue lung cancer non-small cell lung cancer L original research 30274002 Expression of Long Non-Coding RNA PRAL as a Potential Biomarker for Diagnosis in Non-Small-Cell Lung Cancer Patients is Associated with the Inhibition of Cell Proliferation and Metastasis. 88 lncRNA diagnostic biomarker lnc-MICAL3-2 human tissue colon cancer uncertain original research 30269368 Identification of long noncoding RNAs biomarkers for diagnosis and prognosis in patients with colon adenocarcinoma. 89 lncRNA diagnostic biomarker "combine(MALAT1,PCAT1,lnc-FGF1-9)" human urine bladder cancer H original research 30268126 Expression signatures of exosomal long non-coding RNAs in urine serve as novel non-invasive biomarkers for diagnosis and recurrence prediction of bladder cancer 90 lncRNA diagnostic biomarker ITGB2-AS1 human tissue osteosarcoma H original research 30260245 Down-regulation of long non-coding RNA ITGB2-AS1 inhibits osteosarcoma proliferation and metastasis by repressing Wnt/β-catenin signalling and predicts favourable prognosis. 91 lncRNA diagnostic biomarker lnc-IRX3-80 human "tissue,cell" melanoma L original research 30257602 The long non-coding RNA CRNDE competed endogenously with miR-205 to promote proliferation and metastasis of melanoma cells by targeting CCL18 92 lncRNA diagnostic biomarker SNHG17 human tissue gastric cancer H original research 30256413 LncRNA SNHG17 promotes gastric cancer progression by epigenetically silencing of p15 and p57. 93 lncRNA diagnostic biomarker "SNHG12,lnc-POTEH-7" human uncertain bladder cancer L original research 30243082 Identification of oncogenic long noncoding RNA SNHG12 and DUXAP8 in human bladder cancer through a comprehensive profiling analysis. 94 lncRNA diagnostic biomarker "PCAT1,MALAT1,CPS1-IT1" human tissue，plamsa cholangio cancer H original research 30231247 The plasma LncRNA Acting as Fingerprint in Hilar Cholangiocarcinoma. 95 lncRNA diagnostic biomarker RP1-85F18.6 human tissue colorectal cancer H original research 30226619 Biological functions and clinical significance of the newly identified long non?coding RNA RP1?85F18.6 in colorectal cancer. 96 lncRNA diagnostic biomarker LINC00839 human "tissue,cell" gastric cancer L original research 30210707 Low expression of the long non-coding RNA NR_026827 in gastric cancer 97 lncRNA diagnostic biomarker "lnc-GATA6-5,lnc-FDX1-1,FOXCUT" human tissue breast cancer triple-negative breast cancer H original research 30203490 Comprehensive analysis of novel three-long noncoding RNA signatures as a diagnostic and prognostic biomarkers of human triple-negative breast cancer. 98 lncRNA diagnostic biomarker SLCO4A1-AS1 human tissue colorectal cancer H original research 30201010 LncRNA SLCO4A1-AS1 facilitates growth and metastasis of colorectal cancer throughβ-catenin-dependent Wnt pathway. 99 lncRNA diagnostic biomarker lnc-FOXB2-9 human uncertain prostate cancer H review 30200254 RNAs as Candidate diagnostic and Prognostic markers of Prostate cancer-From Cell Line Models to Liquid Biopsies. 100 lncRNA diagnostic biomarker SOX2OT human "tissue,cell" gastric cancer L original research 30198866 Differential expression of long non-coding RNA SOX2OT in gastric adenocarcinoma 101 lncRNA diagnostic biomarker PVT1 human "tissue,cell" ovarian cancer H original research 30197791 LncRNA PVT1 promotes ovarian cancer progression by silencing miR-214. 102 lncRNA diagnostic biomarker "lnc-BMP6-106,ZFAS1" human plasma gastric cancer H original research 30197680 Circulating long non-coding RNAs HULC and ZNFX1-AS1 are potential biomarkers inpatients with gastric cancer. 103 lncRNA diagnostic biomarker "HAND2-AS1,lnc-N6AMT1-1" human uncertain hepatocellular cancer uncertain original research 30186744 "Comprehensive analysis of key genes, microRNAs and long non-coding RNAs in hepatocellular carcinoma." 104 lncRNA diagnostic biomarker "ELFN1-AS1,LINC01234,SNHG17,UCA1,GAU1" human tissue colon cancer H(UCA1) original research 30182733 Screening key long non-coding RNAs in early-stage colon adenocarcinoma by RNA-sequencing. 105 lncRNA diagnostic biomarker AFAP1-AS1 human tissue uncertain Multiple cancers H review 30173945 The role of long non-coding RNA AFAP1-AS1 in human malignant tumors. 106 lncRNA diagnostic biomarker "MAGI2-AS3,ADAMTS9-AS2,LINC00330" human uncertain bladder cancer uncertain original research 30170380 Integrated analysis of a competing endogenous RNA network reveals key lncRNAs as potential prognostic biomarkers for human bladder cancer 107 lncRNA diagnostic biomarker "combine(uc001ncr,AX800134)" human uncertain hepatocellular cancer uncertain review 30159431 "Long noncoding RNAs in the initiation, progression, and metastasis ofhepatocellular carcinoma." 108 lncRNA diagnostic biomarker "combine(CDKN2B-AS1,DSCAM-S1,H19)" human cell breast cancer H original research 30159409 Integrated analysis of dysregulated lncRNA expression in breast cancer cell identified by RNA-seq study 109 lncRNA diagnostic biomarker NEAT1 human cell ovarian cancer high-grade serous ovarian cancer H original research 30154460 "Long noncoding RNA NEAT1, regulated by LIN28B, promotes cell proliferation and migration through sponging miR-506 in high-grade serous ovarian cancer." 110 lncRNA diagnostic biomarker NONHSAT074176.2 human tissue colorectal cancer L original research 30145796 RNA sequencing and bioinformatics analysis of the long noncoding RNA-mRNA network in colorectal cancer. 111 lncRNA diagnostic biomarker lnc-THNSL1-3 human plasma myeloma multiple myeloma uncertain original research 30144133 Circulating exosomal long noncoding RNA PRINS-First findings in monoclonalgammopathies. 112 lncRNA diagnostic biomarker CDKN2B-AS1 human cell leukemia acute myeloid leukemia H original research 30134922 LncRNA ANRIL regulates AML development through modulating the glucose metabolism pathway of AdipoR1/AMPK/ SIRT1 113 lncRNA diagnostic biomarker "combine(HOTAIR,PVT1,LINC01507,lnc-PPIAL4A-2)" human tissue cervical cancer H original research 30134241 Four Circulating Long Non-Coding RNAs Act as Biomarkers for Predicting Cervical Cancer 114 lncRNA diagnostic biomarker MALAT1 human "tissue,serum" lung cancer non-small cell lung cancer H review 30132842 Functions and regulatory mechanisms of metastasis-associated lung adenocarcinoma transcript 1. 115 lncRNA diagnostic biomarker MYU human tissue prostate cancer H original research 30132573 Long non-coding RNA MYU promotes prostate cancer proliferation by mediating the miR-184/c-Myc axis. 116 lncRNA diagnostic biomarker lnc-NTSR2-2 human tissue oral cancer oral squamous cell carcinoma uncertain original research 30128179 "A novel long non-coding RNA, AC012456.4, as a valuable and independent prognostic biomarker of survival in oral squamous cell carcinoma." 117 lncRNA diagnostic biomarker ECM human tissue esophageal cancer esophageal squamous cell carcinoma H original research 30128011 LncRNA-ECM is overexpressed in esophageal squamous cell carcinoma and promotes tumor metastasis. 118 lncRNA diagnostic biomarker MIR210HG human "tissue,cell" pancreatic cancer uncertain original research 30113217 Identification of lncRNAs and Their Functional Network Associated with Chemoresistance in SW1990/GZ Pancreatic Cancer Cells by RNA Sequencing. 119 lncRNA diagnostic biomarker TMPO-AS1 human "tissue,cell" prostate cancer H original research 30105831 Overexpression of AR-regulated lncRNA TMPO-AS1 correlates with tumor progression and poor prognosis in prostate cancer. 120 lncRNA diagnostic biomarker lnc-BMP6-106 human plasma hepatocellular cancer uncertain review 30105249 A Systematic Review of Long Noncoding RNAs in Hepatocellular Carcinoma: Molecular Mechanism and Clinical Implications. 121 lncRNA diagnostic biomarker HOXA11-AS human uncertain uncertain review 30100744 HOXA11-AS: a novel regulator in human cancer proliferation and metastasis. 122 lncRNA diagnostic biomarker LINC00161 human "urine,serum" hepatocellular cancer H original research 30087703 serum and exosome long non coding RNAs as potential biomarkers for hepatocellular carcinoma. 123 lncRNA diagnostic biomarker H19 human serum gastric cancer H original research 30083318 Diagnostic and prognostic value of circulating lncRNA H19 in gastric cancer. 124 lncRNA diagnostic biomarker PVT1 human tissue bladder cancer H original research 30076714 LncRNA PVT1 regulates VEGFC through inhibiting miR-128 in bladder cancer cells. 125 lncRNA diagnostic biomarker "GAS5,H19" human uncertain uncertain H review 30069443 Non-coding RNAs: the riddle of the transcriptome and their perspectives in cancer. 126 lncRNA diagnostic biomarker SNHG12 human tissue，plamsa hepatocellular cancer uncertain original research 30066898 diagnostic utility of sample lncRNA small nucleolar RNA host gene 1 in patients with hepatocellular carcinoma. 127 lncRNA diagnostic biomarker PCDH9-13:1 human "tissue,plasma,saliva" hepatocellular cancer uncertain original research 30045829 Lnc-PCDH9-13:1 Is a Hypersensitive and Specific Biomarker for Early Hepatocellular Carcinoma. 128 lncRNA diagnostic biomarker "ATB,MALAT1,FR0348383,lnc-FOXB2-9" human uncertain prostate cancer "H(ATB,MALAT1,lnc-FOXB2-9)" review 30037351 Pathological bases and clinical impact of long noncoding RNAs in prostate cancer: a new budding star 129 lncRNA diagnostic biomarker LUCAT1 human "tissue,serum" renal cancer clear cell renal cell carcinoma H original research 30032137 Long Non-Coding RNA LUCAT1 Promotes Proliferation and Invasion in Clear Cell Renal Cell Carcinoma Through AKT/GSK-3β Signaling Pathway. 130 lncRNA diagnostic biomarker MALAT1 human tissue lung cancer H original research 30026840 LncRNA MALAT1 negatively regulates MDSCs in patients with lung cancer. 131 lncRNA diagnostic biomarker lnc-FRMD8-1 human blood lung cancer original research 30025752 Circulating lncRNA XLOC_009167 serves as a diagnostic biomarker to predict lung cancer. 132 lncRNA diagnostic biomarker NEAT1 human tissue hepatocellular cancer H original research 30021196 "LncRNA NEAT1 Promotes Deterioration of Hepatocellular Carcinoma Based on In VitroExperiments, Data Mining, and RT-qPCR Analysis." 133 lncRNA diagnostic biomarker lnc-HMGA1-2 human serum hepatocellular cancer uncertain original research 30015383 Role of exosomal competing endogenous RNA in patients with hepatocellular carcinoma. 134 lncRNA diagnostic biomarker LINC00961 human cell lung cancer non-small cell lung cancer. L original research 30010215 Long noncoding RNA LINC00961 inhibits cell proliferation and induces cell apoptosis in human non-small cell lung cancer. 135 lncRNA diagnostic biomarker LINC00857 human tissue gastric cancer L original research 30008909 Long non-coding RNA LINC00857 promotes gastric cancer cell proliferation andpredicts poor patient survival. 136 lncRNA diagnostic biomarker lnc-KLRB1-1 human serum hepatocellular cancer L original research 30008842 Serum long noncoding RNA LRB1 as a potential biomarker for predicting the diagnosis and prognosis of human hepatocellular carcinoma. 137 lncRNA diagnostic biomarker "CAPN10-DT,LINC01093,lnc-COPZ2-1,FENDRR,lnc-TBX2-8" human tissue hepatocellular cancer uncertain original research 29991128 Identification of long noncoding RNAs biomarkers in patients with hepatitis B virus-associated hepatocellular carcinoma. 138 lncRNA diagnostic biomarker lnc-IRX3-80 human tissue uncertain Multiple cancers uncertain original research 29988699 Colorectal neoplasia differentially expressed: a long noncoding RNA with an imperative role in cancer 139 lncRNA diagnostic biomarker MALAT1 human tissue thyroid cancer papillary thyroid cancer H original research 29987950 Upregulation of long noncoding RNA MALAT1 in papillary thyroid cancer and its diagnostic value. 140 lncRNA diagnostic biomarker "CDKN2B-AS1,HIF1A-AS2,UCA1" human plasma breast cancer triple-negative breast cancer H(UCA1) review 29983835 "Long non-coding RNAs: implications in targeted diagnoses, prognosis, and improvedtherapeutic strategies in human non- and triple-negative breast cancer." 141 lncRNA diagnostic biomarker HOXA-AS2 human tissue uncertain Multiple cancers uncertain review 29981289 LncRNA HOXA-AS2 and its molecular mechanisms in human cancer 142 lncRNA diagnostic biomarker UFC1 human cell gastric cancer H original research 29970131 Long non-coding RNA UFC1 promotes gastric cancer progression by regulating miR-498/Lin28b. 143 lncRNA diagnostic biomarker LINC003121 nude mice tissue thyroid cancer uncertain original research 29969438 Long Noncoding RNA LINC003121 Inhibits Proliferation and Invasion of ThyroidCancer Cells by Suppression of the Phosphatidylinositol-3-Kinase (PI3K)/AktSignaling Pathway. 144 lncRNA diagnostic biomarker HOTAIR human cell prostate cancer H original research 29944905 HOTAIR is a REST-regulated lncRNA that promotes neuroendocrine differentiation in castration resistant prostate cancer 145 lncRNA diagnostic biomarker BCAR4 human "tissue,cell" cervical cancer H original research 29937186 Up-regulated BCAR4 contributes to proliferation and migration of cervical cancer cells. 146 lncRNA diagnostic biomarker MALAT1 human tissue uncertain H review 29928382 MALAT1: A long non-coding RNA highly associated with human cancers 147 lncRNA diagnostic biomarker lnc-FOXB2-9 human uncertain hepatocellular cancer H review 29888282 The Diverse Mechanisms of miRNAs and lncRNAs in the Maintenance of Liver Cancer Stem Cells 148 lncRNA diagnostic biomarker LINC00599 human tissue prostate cancer H original research 29887969 Long non-coding RNA RNCR3 promotes prostate cancer progression through targeting miR-185-5p. 149 lncRNA diagnostic biomarker ZNF67-1 human "tissue,cell" nasopharyngeal cancer uncertain review 29805695 Long non-coding RNA ZNF674-1 acts as a cancer suppressor in nasopharyngeal carcinoma 150 lncRNA diagnostic biomarker AFAP1-AS1 human tissue gastric cancer H original research 29805596 "Long non-coding RNA AFAP1-antisense RNA 1 promotes the proliferation, migrationand invasion of gastric cancer cells and is associated with poor patient survival." 151 lncRNA diagnostic biomarker "ENST0000435726,ENST00000585612,ENST00000566734,ENST00000453783,lnc-SNRPN-8,RP11_697E22.2,uc010jub.1,lnc-RCHY1-4" human uncertain ovarian cancer cisplatin-resistant ovarian cancer uncertain original research 29805570 lncRNAs are novel biomarkers for differentiating between cisplatin-resistant and cisplatin-sensitive ovarian cancer. 152 lncRNA diagnostic biomarker "ITGB2-AS1,lnc-TMEM238L-16,LINC01133,LINC01857,PSMB8-AS1,A2M-AS1,DLEU2,MIR155HG,ITGB2-AS1,TSPOAP1-AS1,LINC00205" human uncertain pancreatic cancer pancreatic ductal adenocarcinoma H(LINC01133) original research 29796634 LncRNA co-expression Network Analysis Reveals Novel Biomarkers for Pancreaticcancer. 153 lncRNA diagnostic biomarker "MALAT1,combine(NPTN-IT1,PVT1,PANDAR,PTENP1,lnc00963)" human cell renal cancer "H(MALAT1,PVT1,PANDAR)" review 29794462 Long Non-Coding RNA Emergence During Renal Cell Carcinoma Tumorigenesis. 154 lncRNA diagnostic biomarker UFC1 human tissue cervical cancer H original research 29790665 Long noncoding RNA UFC1 is activated by E2F1 and exerts oncogenic properties by functioning as a ceRNA of FOXP3. 155 lncRNA diagnostic biomarker "MALAT1,MIR210HG" human tissue glioma H(MALAT1) original research 29777909 lncRNAs as potential molecular biomarkers for the clinicopathology and prognosis of glioma: A systematic review and meta-analysis 156 lncRNA diagnostic biomarker ZEB1-AS1 human "tissue,cell" gastric cancer uncertain original research 29771411 Long non-coding RNA ZEB1-AS1 is associated with poor prognosis in gastric cancer and promotes cancer cell metastasis. 157 lncRNA diagnostic biomarker FER1L4 human tissue osteosarcoma L original research 29762833 Low-expression of lncRNA FER1L4 might be a prognostic marker in osteosarcoma. 158 lncRNA diagnostic biomarker "H19,lnc-BMP6-106,HOTAIR,lnc-FOXB2-9" human uncertain prostate cancer "H(H19,HOTAIR)" review 29755696 The use of long non-coding RNAs as prognostic biomarkers and therapeutic targets in prostate cancer. 159 lncRNA diagnostic biomarker LINC01538 human serum colorectal cancer H original research 29737552 Competing endogenous RNA network crosstalk reveals novel molecular markers in colorectal cancer. 160 lncRNA diagnostic biomarker "MALAT1,H19,UCA1" human tissue lung cancer H original research 29731641 Combination of long noncoding RNA MALAT1 and carcinoembryonic antigen for the diagnosis of malignant pleural effusion caused by lung cancer. 161 lncRNA diagnostic biomarker DANCR human tissue uncertain Multiple cancers uncertain review 29728310 LncRNA-DANCR: A valuable cancer related long non-coding RNA for human cancers. 162 lncRNA diagnostic biomarker BANCR human tissue hepatocellular cancer L original research 29725471 Downregulation of BRAF-activated non-protein coding RNA in patients with hepatitis B virus-associated hepatocellular carcinoma. 163 lncRNA diagnostic biomarker "LINC02594,lnc-ZNF609-1,lnc-SLC25A52-4" human plasma gastric cancer uncertain original research 29700972 "A panel consisting of three novel circulating lncRNAs, is it a predictive tool for gastric cancer?" 164 lncRNA diagnostic biomarker BANCR human tissue ovarian cancer epithelial ovarian cancer H original research 29693889 Increased expression of LncRNA BANCR and its prognostic significance in humane pithelial ovarian cancer. 165 lncRNA diagnostic biomarker ATB human tissue uncertain Multiple cancers H original research 29692736 The Function and Mechanism of Long Non-coding RNA-ATB in cancers. 166 lncRNA diagnostic biomarker UEGC1 human "plasma,cell" gastric cancer early-stage gastric cancer H original research 29690888 Tumor-originated exosomal lncUEGC1 as a circulating biomarker for early-stage gastric cancer. 167 lncRNA diagnostic biomarker Dleu2 human tissue laryngeal cancer H original research 29687850 "Long non-coding RNA Dleu2 affects proliferation, migration and invasion abilityof laryngeal carcinoma cells through triggering miR-16-1 pathway." 168 lncRNA diagnostic biomarker "Prcat17.3,Prcat38" human "urine,tissue" prostate cancer H original research 29671889 "Two long non-coding RNAs, Prcat17.3 and Prcat38, could efficiently discriminatebenign prostate hyperplasia from prostate cancer." 169 lncRNA diagnostic biomarker MIR22HG human "tissue,cell" lung cancer L original research 29669758 "Silencing of Long Noncoding RNA MIR22HG Triggers Cell Survival/Death Signaling via Oncogenes YBX1, MET, and p21 in Lung Cancer." 170 lncRNA diagnostic biomarker DQ786243 human serum hepatocellular cancer H original research 29669339 Upregulation of LncDQ is Associated with Poor Prognosis and Promotes Tumor Progression via Epigenetic Regulation of the EMT Pathway in HCC. 171 lncRNA diagnostic biomarker "lnc-BMP6-106,PEG10,p21,HOTAIR,lnc-IGF1R-1,MALAT1" human cell lymphoma diffuse Large B-cell Lymphomas "H(p21,HOTAIR,MALAT1)" original research 29665941 Research on Ralation of Long Non-coding RNA with Diffuse Large B-cell Lymphomas 172 lncRNA diagnostic biomarker "ATB,SETD8" human tissue gastric cancer "H(ATB,SETD8),L(lncRNA-ATB)" original research 29657927 Gene Expression Analysis of Two Epithelial-mesenchymal Transition-related Genes: Long Noncoding RNA-ATB and SETD8 in Gastric Cancer tissues 173 lncRNA diagnostic biomarker VIM-AS1 human uncertain colorectal cancer H original research 29656793 Long noncoding RNA VIM-AS1 promotes colorectal cancer progression and metastasis by inducing EMT. 174 lncRNA diagnostic biomarker AK021443 snail "tissue,cell " hepatocellular cancer H original research 29638164 Long Noncoding RNA AK021443 Promotes Cell Proliferation and Migration by Regulating Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma Cells. 175 lncRNA diagnostic biomarker HOTAIR human serum breast cancer H original research 29630518 Circulating HOTAIR expression predicts the clinical response to neoadjuvant chemotherapy in patients with breast cancer. 176 lncRNA diagnostic biomarker THOR human tissue osteosarcoma uncertain original research 29626476 Long non-coding RNA THOR promotes human osteosarcoma cell growth in vitro andin vivo. 177 lncRNA diagnostic biomarker "EMX20S,lnc-DLK1-35,SYS1-DBNDD2,MIR9-3HG" human uncertain cervical cancer "H(DDX12P,GOLGA2P5,GOLGA2P10,LINC00467,MIR9-3HG,MST1P2,TMPO-AS1),L(EMX2OS,LINC 00663,MEG 3,SYS1-DBNDD2)" original research 29620291 Integrated analysis of long non?coding RNA competing interactions revealedpotential biomarkers in cervical cancer: Based on a public database. 178 lncRNA diagnostic biomarker "SAP30L-AS1,SCHLAP1" human "plasma,serum" prostate cancer H original research 29614511 Tumor-Derived Exosomal Long Noncoding RNAs as Promising Diagnostic Biomarkers for Prostate Cancer 179 lncRNA diagnostic biomarker "MALAT1,HOTAIR,H19,CCAT" human uncertain colorectal cancer H review 29614491 The Biological Effect and Clinical Application of Long Noncoding RNAs in Colorectal Cancer. 180 lncRNA diagnostic biomarker Lnc-OC1 human tissue ovarian cancer H original research 29576507 "A novel lncRNA, Lnc-OC1, promotes ovarian cancer cell proliferation and migration by sponging miR-34a and miR-34c." 181 lncRNA diagnostic biomarker GIHCG human uncertain renal cancer uncertain review 29565468 Long noncoding RNA GIHCG is a potential diagnostic and prognostic biomarker andtherapeutic target for renal cell carcinoma. 182 lncRNA diagnostic biomarker "LINC00512,CRNDE-h" human uncertain uncertain uncertain review 29558960 The decade of exosomal long RNA species: an emerging cancer antagonist 183 lncRNA diagnostic biomarker HOTAIR human serum glioma glioblastoma H original research 29558959 Serum long noncoding RNA HOTAIR as a novel diagnostic and prognostic biomarker in glioblastoma multiforme. 184 lncRNA diagnostic biomarker "lnc-IRX3-80,lnc-BMP6-106" human "tissue,uncertain" uncertain uncertain review 29556906 Long noncoding RNAs in the mTOR signaling network: biomarkers and therapeutic targets 185 lncRNA diagnostic biomarker H19 human uncertain gastric cancer H review 29552712 Epigenetic Mechanisms and Events in Gastric Cancer-Emerging Novel Biomarkers. 186 lncRNA diagnostic biomarker HOTAIR human tissue uncertain H original research 29534577 The association between LncRNA HOTAIR and cancer lymph node metastasis and distant metastasis: a meta-analysis. 187 lncRNA diagnostic biomarker WSPAR human tissue colorectal cancer H original research 29532890 Long non-coding RNA TCF7 predicts the progression and facilitates the growth and metastasis of colorectal cancer. 188 lncRNA diagnostic biomarker lnc-TMEM238L-16 human tissue colorectal cancer L original research 29524886 Long non-coding RNA Linc00675 suppresses cell proliferation and metastasis in colorectal cancer via acting on miR-942 and Wnt/β-catenin signaling. 189 lncRNA diagnostic biomarker NNT-AS1 human tissue osteosarcoma H original research 29518771 Overexpression of Long Non-Coding RNA NNT-AS1 Correlates with Tumor Progression and Poor prognosis in Osteosarcoma. 190 lncRNA diagnostic biomarker "uc004cox.4,GAS5" human urine bladder cancer H(GAS5) original research 29516641 Cell-free lncRNA expression signatures in urine serve as novel non-invasivebiomarkers for diagnosis and recurrence prediction of bladder cancer. 191 lncRNA diagnostic biomarker MACC1-AS1 human tissue gastric cancer H original research 29510730 The lncRNA MACC1-AS1 promotes gastric cancer cell metabolic plasticity viaAMPK/Lin28 mediated mRNA stability of MACC1 192 lncRNA diagnostic biomarker "combine(SOX2OT,CDKN2B-AS1,CYFRA21-1)" human tissue lung cancer non-small cell lung cancer uncertain original research 29504701 Circulating long noncoding RNA act as potential novel biomarkers for diagnosis and prognosis of non-small cell lung cancer. 193 lncRNA diagnostic biomarker LINC00472 human uncertain colorectal cancer L original research 29488624 "Regulatory network analysis of LINC00472, a long noncoding RNA downregulated by DNA hypermethylation in colorectal cancer." 194 lncRNA diagnostic biomarker "ATB,GAS8-AS1" human plasma thyroid cancer H(ATB) original research 29487006 The diagnostic and prognostic significance of long noncoding RNAs expression in thyroid cancer: A systematic review and meta-analysis. 195 lncRNA diagnostic biomarker HOTTIP human serum gastric cancer H original research 29486794 Exosomal long noncoding RNA HOTTIP as potential novel diagnostic and prognostic biomarker test for gastric cancer. 196 lncRNA diagnostic biomarker lnc-FGF1-9 human uncertain uncertain Multiple cancers H review 29484753 The long non-coding RNA SPRY4-IT1: An emerging player in tumorigenesis and osteosarcoma. 197 lncRNA diagnostic biomarker H19 human serum myeloma multiple myeloma H original research 29470951 Serum level of long noncoding RNA H19 as a diagnostic biomarker of multiplemyeloma. 198 lncRNA diagnostic biomarker SNHG12 human "tissue,cell" lung cancer non-small cell lung cancer H original research 29466052 Long noncoding RNA SNHG1 promotes non-small cell lung cancer progression by up-regulating MTDH via sponging miR-145-5p. 199 lncRNA diagnostic biomarker FGFR3-AS human cell hepatocellular cancer H original research 29463348 Long Noncoding RNA FGFR3-AS1 Promotes Hepatocellular Carcinoma Carcinogenesis via Modulating the PI3K/AKT Pathway. 200 lncRNA diagnostic biomarker HOTAIR human uncertain head and neck cancer head and neck squamous cell carcinoma H original research 29461598 Association on polymorphisms in LncRNA HOTAIR and susceptibility to HNSCC in Chinese population. 201 lncRNA diagnostic biomarker "TUSC8,TUSC8" human tissue colorectal cancer L original research 29436686 Downregulation of the long non-coding RNA XLOC_010588 inhibits the invasion andmigration of colorectal cancer. 202 lncRNA diagnostic biomarker LINC-ROR human tissue esophageal cancer esophageal squamous cell carcinoma. L original research 29430188 LincRNA-ROR promotes metastasis and invasion of esophageal squamous cell carcinoma by regulating miR-145/FSCN1. 203 lncRNA diagnostic biomarker CASC9 human "tissue,cell" esophageal cancer esophageal squamous cell carcinoma. H original research 29424900 LncRNA CASC9 promotes tumorigenesis by affecting EMT and predicts poor prognosis in esophageal squamous cell cancer. 204 lncRNA diagnostic biomarker FALEC human "tissue,serum,cell" hepatocellular cancer H original research 29421439 LncRNA FAL1 promotes cell proliferation and migration by acting as a CeRNA of miR-1236 in hepatocellular carcinoma cells. 205 lncRNA diagnostic biomarker DANCR human "tissue,serum" gastric cancer H original research 29416741 Long noncoding RNA DANCR is activated by SALL4 and promotes the proliferation andinvasion of gastric cancer cells. 206 lncRNA diagnostic biomarker "lnc-MGAT1-4,FOXCUT,FTH1P3,HOTAIR,TUG1,UCA1,PTENP1,FALEC,HOTAIR,LINC02082,NEAT1,lnc-ABCA12-8,GASS-AS1,lnc-ALG2-6,lnc-RPS6KL1-1,GAS8-AS1,HOTAIR,H19,HNGA1,HOTAIR,MALALT-1,MALAT1,PVT1,UCA1" human uncertain;tissue;uncertain;tissue;saliva;uncertain;uncertain;uncertain head and neck cancer "H(HOTAIR,TUG1,UCA1,PTENP1,HOTAIR,H19,PVT1)" review 29416703 Current research on head and neck cancer-associated long noncoding RNAs. 207 lncRNA diagnostic biomarker ESCCAL_1 mice uncertain esophageal cancer esophageal squamous cell carcinoma L original research 29416654 Down-regulation of long non-coding RNA ESCCAL_1 inhibits tumor growth ofesophageal squamous cell carcinoma in a xenograft mouse model. 208 lncRNA diagnostic biomarker "CFP-1:1,lnc-CD164L2-1" human uncertain hepatocellular cancer uncertain original research 29416609 Alcohol and hepatitis virus-dysregulated lncRNAs as potential biomarkers for hepatocellular carcinoma. 209 lncRNA diagnostic biomarker PANDAR human cell gastric cancer H original research 29416011 Long noncoding RNA PANDAR blocks CDKN1A gene transcription by competitive interaction with p53 protein in gastric cancer. 210 lncRNA diagnostic biomarker "lnc-CRYBA4-52,SNORD114-10" human tissue ovarian cancer H original research 29387224 Preliminary screening and identification of differentially expressed metastasis-related ncRNAs in ovarian cancer. 211 lncRNA diagnostic biomarker CYTOR human plasma lung cancer non-small cell lung cancer H original research 29375177 dentification of Circulating Long Noncoding RNA Linc00152 as a Novel Biomarkerfor diagnosis and Monitoring of Non-Small-Cell Lung Cancer. 212 lncRNA diagnostic biomarker FAS-AS1 human blood leukemia acute myeloid leukemia uncertain original research 29373891 Fas-Antisense Long Noncoding RNA and Acute Myeloid leukemia: Is There any Relation? 213 lncRNA diagnostic biomarker HOTTIP human uncertain lung cancer small cell lung cancer H original research 29367594 Long non-coding RNA HOTTIP promotes BCL-2 expression and induces chemoresistance in small cell lung cancer by sponging miR-216a. 214 lncRNA diagnostic biomarker GIHCG human tissue renal cancer H original research 29364470 Long noncoding RNA GIHCG is a potential diagnostic and prognostic biomarker andtherapeutic target for renal cell carcinoma. 215 lncRNA diagnostic biomarker NEAT1 human cell gastric cancer "H(NEAT1,STAT3),L(miR-506)" original research 29363783 Long noncoding RNA NEAT1-modulated miR-506 regulates gastric cancer development through targeting STAT3. 216 lncRNA diagnostic biomarker SLC7A11-AS1 human cell gastric cancer L original research 29348845 Decreased expression of the long non-coding RNA SLC7A11-AS1 predicts poor prognosis and promotes tumor growth in gastric cancer. 217 lncRNA diagnostic biomarker lnc-CRYBA4-52 human tissue breast cancer L original research 29345338 MIAT lncRNA is overexpressed in breast cancer and its inhibition triggers senescence and G1 arrest in MCF7 cell line. 218 lncRNA diagnostic biomarker XIXT human blood hepatocellular cancer H original research 29344104 X-inactive-specific transcript of peripheral blood cells is regulated by exosomal Jpx and acts as a biomarker for female patients with hepatocellular carcinoma. 219 lncRNA diagnostic biomarker SNHG12 human tissue colorectal cancer H original research 29340086 Up-regulation of lncRNA SNHG1 indicates poor prognosis and promotes cell proliferation and metastasis of colorectal cancer by activation of the Wnt/β-catenin signaling pathway. 220 lncRNA diagnostic biomarker UCA1 human uncertain thyroid cancer H original research 29340074 "These studies highlight the potential of lncRNA UCA1 as a diagnostic and prognostic biomarker, and a therapeutic target in malignant tumors." 221 lncRNA diagnostic biomarker NEAT1 human cell breast cancer L original research 29323713 NEAT1 contributes to breast cancer progression through modulating miR-448 and ZEB1. 222 lncRNA diagnostic biomarker "MALAT1,TUG1,p21,HOTAIR,GAS5" human uncertain uncertain H review 29307231 The potential of circulating cell-free RNA as a cancer biomarker: challenges and opportunities 223 lncRNA diagnostic biomarker "combine(CEBPA-DT,AK001058,INHBA-AS1,ENST00000609220,CEBPA-DT,lnc-FOXB2-9)" human cell oral cancer oral squamous cell carcinoma H original research 29281558 Long non-coding RNA CEBPA-AS1 correlates with poor prognosis and promotes tumorigenesis via CEBPA/Bcl2 in oral squamous cell carcinoma. 224 lncRNA diagnostic biomarker MIR4435-2HG mice "tissue,serum,cell" gastric cancer L original research 29271006 Long noncoding RNA LINC00978 promotes cancer growth and acts as a diagnostic biomarker in gastric cancer 225 lncRNA diagnostic biomarker TUG1 human "cell,serum" lung cancer non small cell lung cancer H original research 29254212 Long noncoding RNA TUG1 is a diagnostic factor in lung adenocarcinoma and suppresses apoptosis via epigenetic silencing of BAX. 226 lncRNA diagnostic biomarker "MALAT1,HOTAIR,RPL34-AS1,PCAT1" human uncertain colorectal cancer "H(MALAT1,HOTAIR,PCAT1)" original research 29254165 A long non-coding RNA expression signature to predict survival of patients with colon adenocarcinoma. 227 lncRNA diagnostic biomarker FEZF1-AS1 human "tissue,cell" gastric cancer L original research 29239821 Long noncoding RNA FEZF1-AS1 indicates a poor prognosis of gastric cancer and promotes tumorigenesis via activation of Wnt signaling pathway 228 lncRNA diagnostic biomarker PCAT6 human tissue lung cancer non-small cell lung cancer H original research 29238201 Diagnostic significance of circulating long noncoding RNA PCAT6 in patients with non-small cell lung cancer. 229 lncRNA diagnostic biomarker SNHG16 human tissue bladder cancer H original research 29234154 LncRNA-SNHG16 predicts poor Prognosis and promotes tumor proliferation through epigenetically silencing p21 in bladder cancer. 230 lncRNA diagnostic biomarker lnc-FAM84B-15 human "plasma,tissue" myeloma multiple myeloma H original research 29228867 Long non-coding RNA CCAT1 promotes multiple myeloma progression by acting as amolecular sponge of miR-181a-5p to modulate HOXA1 expression. 231 lncRNA diagnostic biomarker lnc-USP6NL-7 human tissue lung cancer lung squamous cellcarcinoma. H original research 29228625 Long noncoding RNA SFTA1P promoted apoptosis and increased cisplatinchemosensitivity via regulating the hnRNP-U-GADD45A axis in lung squamous cellcarcinoma. 232 lncRNA diagnostic biomarker MALAT1 mice cell septicemia H original research 29227823 LncRNA MALAT1 regulates sepsis-induced cardiac inflammation and dysfunction via interaction with miR-125b and p38 MAPK/NFκB. 233 lncRNA diagnostic biomarker PANDAR human uncertain uncertain Multiple cancers H review 29226461 Long non-coding PANDAR as a novel biomarker in human cancer: A systematic review. 234 lncRNA diagnostic biomarker UCA1 human "urine,tissue,blood" bladder cancer H review 29224950 "mRNA, microRNA and lncRNA as novel bladder tumor markers." 235 lncRNA diagnostic biomarker NEAT1 human cell hepatocellular cancer H original research 29219178 The long noncoding RNA NEAT1 contributes to hepatocellular carcinoma development by sponging miR-485 and enhancing the expression of the STAT3. 236 lncRNA diagnostic biomarker BANCR human tissue uncertain Multiple cancers H review 29212285 BANCR: a novel oncogenic long non-coding RNA in human cancers 237 lncRNA diagnostic biomarker EGOT human tissue gastric cancer L original research 29209988 LncRNA EGOT Promotes Tumorigenesis Via Hedgehog Pathway in Gastric Cancer. 238 lncRNA diagnostic biomarker SNHG12 human tissue gastric cancer H original research 29207106 LncRNA SNHG12 regulates gastric cancer progression by acting as a molecularsponge of miR?320 239 lncRNA diagnostic biomarker "Ccat2,Has2-As1,HOTAIR,MALAT1" human cell oral cancer "H(HOTAIR,MALAT1)" review 29206174 A Looking-Glass of Non-Coding RNAs in Oral Cancer 240 lncRNA diagnostic biomarker "CBR3-AS1,TUG1" human tissue gastric cancer H original research 29182008 Aberrant expression of PlncRNA-1 and TUG1: potential biomarkers for gastric cancer diagnosis and clinically monitoring cancer progression. 241 lncRNA diagnostic biomarker LINC02015 human tissue colorectal cancer H original research 29181105 Overexpression of long non-coding RNA colon cancer-associated transcript 2 is associated with advanced tumor progression and poor prognosis in patients with colorectal cancer. 242 lncRNA diagnostic biomarker "combine(lnc-FGF1-9,NEAT1,CDKN2B-AS1),lnc-FGF1-9" human uncertain ovarian cancer uncertain review 29179183 Long Non-Coding RNAs: the New Horizon of Gene Regulation in Ovarian Cancer 243 lncRNA diagnostic biomarker "lnc-IRX3-80,KCNQ1OT1" human uncertain colorectal cancer uncertain review 29158793 Long non-coding RNAs in Colorectal Cancer: Progression and Future Directions 244 lncRNA diagnostic biomarker "ecCEBPA,UCA1" human "tissue,cell" gastric cancer H(UCA1) original research 29147491 Augmented expression levels of lncRNAs ecCEBPA and UCA1 in gastric cancer tissues and their clinical significance. 245 lncRNA diagnostic biomarker "LINC00271,lnc-DLK1-35,lnc-ALG2-6,PTCSC1,PTCSC2,PTCSC1,CDKN2B-AS1,FALEC,H19,PVT1" human uncertain thyroid cancer "H(H19,PVT1)" review 29146581 Long noncoding RNAs: emerging players in thyroid cancer pathogenesis. 246 lncRNA diagnostic biomarker HNF1A-AS1 human cell colorectal cancer H original research 29145164 Long noncoding RNA HNF1A-AS1 indicates a poor prognosis of colorectal cancer and promotes carcinogenesis via activation of the Wnt/β-catenin signaling pathway. 247 lncRNA diagnostic biomarker MALAT1 human saliva head and neck cancer head and neck squamous cell carcinoma H review 29134827 "Serum, plasma and saliva biomarkers for head and neck cancer" 248 lncRNA diagnostic biomarker PVT1 mice tissue lung cancer non-small cell lung cancer H original research 29133127 Knockdown of LncRNA PVT1 inhibits tumorigenesis in non-small-cell lung cancer by regulating miR-497 expression 249 lncRNA diagnostic biomarker PANDAR human tissue cervical cancer H original research 29131264 Upregulation of LncRNA PANDAR predicts poor prognosis and promotes cell proliferation in cervical cancer. 250 lncRNA diagnostic biomarker "CYTOR,lnc-RC3H1-1,XLOC014172" human plasma hepatocellular cancer uncertain original research 29130980 Circulating LncRNAs Serve as Diagnostic Markers for Hepatocellular Carcinoma. 251 lncRNA diagnostic biomarker "HOTAIR,lnc-BMP6-106,PEG10,lnc-IGF1R-1" human tissue lymphoma "H(HOTAIR,PEG10)" original research 29121780 Long noncoding RNA identification in lymphoma 252 lncRNA diagnostic biomarker SNHG12 human tissue osteosarcoma H original research 29115574 Long non-coding RNA SNHG1 regulates NOB1 expression by sponging miR-326 andpromotes tumorigenesis in osteosarcoma 253 lncRNA diagnostic biomarker lnc-TMEM238L-16 human tissue gastric cancer uncertain original research 29107103 Long noncoding RNA LINC00675 enhances phosphorylation of vimentin on Ser83 tosuppress gastric cancer progression 254 lncRNA diagnostic biomarker HNF1A-AS1 human tissue bladder cancer L original research 29100339 Long non-coding RNA HNF1A-AS1 promotes proliferation and suppresses apoptosis of bladder cancer cells through upregulating Bcl-2. 255 lncRNA diagnostic biomarker NEAT1 human cell lung cancer non-small cell lung cancer L original research 29095526 NEAT1/hsa-mir-98-5p/MAPK6 axis is involved in non-small-cell lung cancer development. 256 lncRNA diagnostic biomarker PVT1 human serum uncertain H original research 29088881 LncRNA PVT1 as an effective biomarker for cancer diagnosis and detection based on transcriptome data and meta-analysis. 257 lncRNA diagnostic biomarker LINC02027 human tissue hepatocellular cancer L original research 29085452 Decreased expression of long non-coding RNA LOC728290 in human hepatocellular carcinoma. 258 lncRNA diagnostic biomarker AFAP1-AS1 human serum lung cancer non-small cell lung cancer. H original research 29080690 Serum AFAP1-AS1 could serve as an ideal combined biomarker for thediagnosis of non-small cell lung cancer. 259 lncRNA diagnostic biomarker PANDAR human "cell,serum" lymphoma diffuse large B-cell lymphoma H original research 29069778 Discovery and validation of the tumor-suppressive function of long noncoding RNA PANDA in human diffuse large B-cell lymphoma through the inactivation of MAPK/ERKsignaling pathway. 260 lncRNA diagnostic biomarker "H19,CYTOR,FER1L4" human tissue gastric cancer H(H19) original research 29060927 Long intergenic non-protein coding RNA 1006 used as a potential novel biomarker of gastric cancer. 261 lncRNA diagnostic biomarker PVT1 human tissue prostate cancer H original research 29050519 LncRNA PVT1 predicts prognosis and regulates tumor growth in prostate cancer. 262 lncRNA diagnostic biomarker "XIST,lnc-EPCAM-8,RRP1B,lnc-DAAM2-9" human tissue gastric cancer H original research 29039538 Potential lncRNA diagnostic biomarkers for early gastric cancer. 263 lncRNA diagnostic biomarker HOTTIP human uncertain hepatocellular cancer H original research 29039502 "Long non?coding RNA HOTTIP promotes hepatocellular carcinoma tumorigenesis and development: A comprehensive investigation based on bioinformatics, qRT?PCR and meta?analysis of 393 cases." 264 lncRNA diagnostic biomarker BLACAT1 human serum uncertain "pan cancer,endometrial cancer" H original research 29037201 Evaluation on the diagnostic and prognostic values of long non-coding RNA BLACAT1 in common types of human cancer. 265 lncRNA diagnostic biomarker lnc-DGCR6-6 human "tissue,cell" lung cancer non small cell lung cancer L original research 29030962 LncRNA DGCR5 promotes lung adenocarcinoma (LUAD) progression via inhibiting hsa-mir-22-3p. 266 lncRNA diagnostic biomarker GAS5 human uncertain uncertain H original research 29029523 Systematic review and meta-analysis of the utility of long non-coding RNA GAS5 as a diagnostic and prognostic cancer biomarker. 267 lncRNA diagnostic biomarker UBE2CP3 human serum hepatocellular cancer H original research 29029437 Long non-coding RNA UBE2CP3 promotes tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma. 268 lncRNA diagnostic biomarker lnc-BMP6-106 human uncertain uncertain Multiple cancers H original research 29026319 Current advances of long non-coding RNA highly upregulated in liver cancer in human tumors. 269 lncRNA diagnostic biomarker LINC00460 human tissue nasopharyngeal cancer H original research 28987345 LncRNA-LINC00460 facilitates nasopharyngeal carcinoma tumorigenesis through sponging miR-149-5p to up-regulate IL6. 270 lncRNA diagnostic biomarker GAS5 human uncertain nasopharyngeal cancer H original research 28977945 Genetic polymorphisms of long non-coding RNA GAS5 predict platinum-based concurrent chemoradiotherapy response in nasopharyngeal carcinoma patients. 271 lncRNA diagnostic biomarker HOTAIR human tissue gastric cancer H original research 28970725 HOX transcript antisense intergenic RNA represses E-cadherin expression by binding to EZH2 in gastric cancer. 272 lncRNA diagnostic biomarker UCA1 human uncertain uncertain H review 28969100 LncRNA UCA1 in anti-cancer drug resistance. 273 lncRNA diagnostic biomarker LINC01268 human tissue glioma H original research 28959170 "Expression of LOC285758, a Potential Long Non-coding Biomarker, is Methylation-dependent and Correlates with Glioma Malignancy Grade." 274 lncRNA diagnostic biomarker lnc-AGO2-1 human tissue colorectal cancer L original research 28954383 Long non-coding RNA CASC7 inhibits the proliferation and migration of coloncancer cells via inhibiting microRNA-21. 275 lncRNA diagnostic biomarker HIF1A-AS1 human serum colorectal cancer H original research 28946548 Elevated serum level of lncRNA-HIF1A-AS1 as a novel diagnostic predictor for worse prognosis in colorectal carcinoma. 276 lncRNA diagnostic biomarker LINC00460 human cell esophageal cancer esophageal squamous cell carcinoma H original research 28939763 A novel long noncoding RNA linc00460 up-regulated by CBP/P300 promotes carcinogenesis in esophageal squamous cell carcinoma. 277 lncRNA diagnostic biomarker AFAP1-AS1 nude mice tissue cholangio cancer H original research 28938565 LncRNA AFAP1-AS1 promotes growth and metastasis of cholangiocarcinoma cells. 278 lncRNA diagnostic biomarker SNHG6 human tissue "breast cancer,lung cancer" L original research 28938549 Long non-coding RNAs may serve as biomarkers in breast cancer combined with primary lung cancer 279 lncRNA diagnostic biomarker ENSG00000244020 human tissue renal cancer clear cell renal cell carcinoma H original research 28928816 Analysis of long non-coding RNA expression profiles in clear cell renal cellcarcinoma. 280 lncRNA diagnostic biomarker LINC00968 human "tissue,cell" lung cancer non-small cell lung cancer H original research 28926089 Long non-coding RNA LINC00968 acts as oncogene in NSCLC by activating the Wnt signaling pathway 281 lncRNA diagnostic biomarker TUG1 human uncertain uncertain H review 28901436 Taurine?upregulated gene 1: A vital long non?coding RNA associated with cancer in humans (Review). 282 lncRNA diagnostic biomarker "lnc-FGF1-9,CDKN2B-AS1,NEAT1" human uncertain uncertain Multiple cancers uncertain review 28895353 [Circulating long noncoding RNAs as biomarkers in tumor diagnosis].(循环长链非编码RNA作为生物标志物在肿瘤分子诊断中的应用) 283 lncRNA diagnostic biomarker "LINC00312,FENDRR" human tissue lung cancer non small cell lung cancer uncertain original research 28881680 Identification of dysregulated long non-coding RNAs/microRNAs/mRNAs in TNM I stage lung adenocarcinoma. 284 lncRNA diagnostic biomarker BNC2-AS1 human tissue gastric cancer H original research 28879717 Increased Expression of Long Noncoding RNA RP11-62F24.2 in Gastric Cancer and ItsClinical Significance. 285 lncRNA diagnostic biomarker "combine(ADARB2-AS1,CDKN2B-AS1,GLIS3-AS1,LINC00472,lnc-DLK1-35,PANDAR,PVT1,UCA1)" human plasma mucinous neoplasm intraductal papillary mucinous neoplasm "H(PVT1,UCA1,PANDAR)" original research 28874676 Linc-ing Circulating Long Non-coding RNAs to the diagnosis and Malignant Prediction of Intraductal Papillary Mucinous Neoplasms of the Pancreas. 286 lncRNA diagnostic biomarker HNF1A-AS1 human tissue osteosarcoma H original research 28866868 The lncRNA HNF1A-AS1 is a negative prognostic factor and promotes tumorigenesisin osteosarcoma. 287 lncRNA diagnostic biomarker lnc-FOXB2-9 human tissue ovarian cancer epithelial ovarian cancer H original research 28864116 The role of long non-coding RNA PCA3 in epithelial ovarian carcinoma tumorigenesis and progression. 288 lncRNA diagnostic biomarker MALAT1 human uncertain pancreatic cancer H original research 28860807 "Clinical significance and prospective molecular mechanism of MALAT1 in pancreatic cancer exploration: a comprehensive study based on the GeneChip, GEO, Oncomine, and TCGA databases." 289 lncRNA diagnostic biomarker "combine(XIST,HIF1A-AS1,UCA1)" human serum hepatocellular cancer H original research 28856933 Serum long noncoding RNA urothelial carcinoma-associated 1: A novel biomarker for diagnosis and prognosis of hepatocellular carcinoma 290 lncRNA diagnostic biomarker CASC9 human cell esophageal cancer esophageal squamous cell carcinoma L original research 28854977 Up-regulation of lncRNA CASC9 promotes esophageal squamous cell carcinoma growth by negatively regulating PDCD4 expression through EZH2 291 lncRNA diagnostic biomarker PAX8-AS1 human uncertain cervical cancer uncertain review 28849103 Long non-coding RNAs on the stage of cervical cancer (Review) 292 lncRNA diagnostic biomarker "lncRNA00312,lncRNA00673" human tissue lung cancer non-small cell lung cancer L original research 28849087 Identification of long non-coding RNA 00312 and 00673 in human NSCLC tissues 293 lncRNA diagnostic biomarker Z38 human tissue renal cancer H original research 28849012 Long non-coding RNA Z38 promotes cell proliferation and metastasis in human renalcell carcinoma 294 lncRNA diagnostic biomarker UCA1 human serum bladder cancer H original research 28841829 Hypoxic exosomes facilitate bladder tumor growth and development through transferring long non-coding RNA-UCA1. 295 lncRNA diagnostic biomarker lnc-FOXB2-9 human urine prostate cancer H review 28807541 Urinary RNA-based biomarkers for prostate cancer detection. 296 lncRNA diagnostic biomarker HOTAIR human plasma lung cancer non-small cell lung cancer H original research 28784052 Identification of Circulating Long Noncoding RNA HOTAIR as a Novel Biomarker for Diagnosis and Monitoring of Non-Small Cell Lung Cancer. 297 lncRNA diagnostic biomarker GAS8-AS1 human plasma thyroid cancer papillary thyroid cancer L original research 28781594 Plasma lncRNA GAS8-AS1 as a Potential Biomarker of Papillary Thyroid Carcinoma in Chinese Patients. 298 lncRNA diagnostic biomarker ATB human tissue thyroid cancer papillary thyroid cancer H original research 28770959 The expression and function of long noncoding RNA lncRNA-ATB in papillary thyroid cancer. 299 lncRNA diagnostic biomarker lnc-NXPE2-1 human tissue lung cancer non-small cell lung cancer H original research 28765887 Down-regulation of long noncoding RNA RP11-713B9.1 contributes to the cell viability in non-small cell lung cancer (NSCLC) 300 lncRNA diagnostic biomarker lnc-FAM84B-15 human uncertain bladder cancer uncertain original research 28759252 Long Noncoding RNA cancer Susceptibility Candidate 8 Suppresses the Proliferation of Bladder cancer Cells via Regulating Glycolysis. 301 lncRNA diagnostic biomarker CASC2 human cell glioma L original research 28744130 Long noncoding RNA CASC2 predicts the prognosis of glioma patients and functions as a suppressor for gliomas by suppressing Wnt/β-catenin signaling pathway. 302 lncRNA diagnostic biomarker "H19,lnc-FOXB2-9" human plasma;serum reproductive system cancer H review 28736855 “Lnc”-ing Wnt in Female Reproductive Cancers: Therapeutic Potential of Long Noncoding RNAs in Wnt Signaling 303 lncRNA diagnostic biomarker DQ786243 human tissue gastric cancer H original research 28731138 Upregulation of long non-coding RNA DQ786243 promotes the progression of gastric cancer. 304 lncRNA diagnostic biomarker NEAT1 human tissue breast cancer H original research 28720546 The lncRNA NEAT1 facilitates cell growth and invasion via the miR-211/HMGA2 axis in breast cancer. 305 lncRNA diagnostic biomarker "HOTAIR,lnc-FOXB2-9,PCAT1,PRNCR1,PCGEM,PlncRNA1,PCAT18,UCA1" human uncertain;urine;uncertain;urine uncertain "H(HOTAIR,PCAT1,UCA1,lnc-FOXB2-9)" review 28701486 Long Noncoding RNA and Cancer: A New Paradigm 306 lncRNA diagnostic biomarker HOTAIR human blood leukemia acute myeloid leukemia H original research 28669171 HOTAIR Long Noncoding RNA is not a Biomarker for Acute Myeloid leukemia (AML) in Iranian Patients 307 lncRNA diagnostic biomarker CASC2 human tissue thyroid cancer L original research 28654795 Low expression of long noncoding RNA CASC2 indicates a poor prognosis and promotes tumorigenesis in thyroid carcinoma 308 lncRNA diagnostic biomarker MALAT1 human tissue bladder cancer H original research 28648755 High expression of long non-coding RNA MALAT1 indicates a poor prognosis and promotes clinical progression and metastasis in bladder cancer 309 lncRNA diagnostic biomarker "SHOX2,RASSF1A" human uncertain lung cancer uncertain review 28644958 Translating cancer epigenomics into the clinic: focus on lung cancer. 310 lncRNA diagnostic biomarker "HOTAIR,lnc-IL17RA-33,UCA1" human uncertain pancreatic cancer "H(HOTAIR,UCA1)" original research 28639886 "A competing endogenous RNA network identifies novel mRNA, miRNA and lncRNAmarkers for the prognosis of diabetic pancreatic cancer." 311 lncRNA diagnostic biomarker MALAT1 human serum lung cancer non-small cell lung cancer H original research 28623135 Serum long non coding RNA MALAT-1 protected by exosomes is up-regulated and promotes cell proliferation and migration in non-small cell lung cancer. 312 lncRNA diagnostic biomarker "GACAT1,lnc-BMP6-106,lnc-SLC25A16-2" human tissue gastric cancer H(GACAT1) original research 28588775 A meta-analysis: The diagnostic values of long non-coding RNA as a biomarker for gastric cancer. 313 lncRNA diagnostic biomarker LINC01315 human tissue nasopharyngeal cancer H original research 28588717 lncRNA C22orf32-1 contributes to the tumorigenesis of nasopharyngeal carcinoma. 314 lncRNA diagnostic biomarker FALEC human tissue prostate cancer H original research 28585762 Upregulation of the long non-coding RNA FALEC promotes proliferation and migration of prostate cancer cell lines and predicts prognosis of PCa patients. 315 lncRNA diagnostic biomarker CCEPR human cell bladder cancer urothelial bladder carcinoma H original research 28574830 Increased expression of long non-coding RNA CCEPR is associated with poor prognosis and promotes tumorigenesis in urothelial bladder carcinoma. 316 lncRNA diagnostic biomarker LINC01672 human cell breast cancer L original research 28550685 Long Noncoding RNA CAMTA1 Promotes Proliferation and Mobility of the Human Breast Cancer Cell Line MDA-MB-231 via Targeting miR-20b. 317 lncRNA diagnostic biomarker LINC02015 human tissue ovarian cancer epithelial ovarian cancer uncertain original research 28550684 Long Noncoding RNA CCAT2 Knockdown Suppresses Tumorous Progression by SpongingmiR-424 in Epithelial Ovarian Cancer 318 lncRNA diagnostic biomarker "MALAT1,UCA1" human uncertain myeloma multiple myeloma H original research 28543758 Deregulated expression of long non-coding RNA UCA1 in multiple myeloma. 319 lncRNA diagnostic biomarker lnc-FOXB2-9 human uncertain prostate cancer H original research 28540248 Long non-coding RNAs: new frontiers for advancing personalized cancer medicine in prostate cancer 320 lncRNA diagnostic biomarker AB019562 human tissue hepatocellular cancer H original research 28534955 Long non?coding RNA AB019562 promotes cell proliferation and metastasis in human hepatocellular carcinoma. 321 lncRNA diagnostic biomarker H19 human tissue cholangio cancer H original research 28528181 Overexpression of long noncoding RNA H19 indicates a poor prognosis for cholangiocarcinoma and promotes cell migration and invasion by affecting epithelial-mesenchymal transition. 322 lncRNA diagnostic biomarker GAS5 human tissue colorectal cancer H original research 28521420 "Long non-coding RNA GAS5 inhibits cell proliferation, induces G0/G1 arrest andapoptosis, and functions as a prognostic marker in colorectal cancer." 323 lncRNA diagnostic biomarker "FEZF1-AS1,HOTAIR,LINC01234" human tissue gastric cancer H(HOTAIR) original research 28484081 Identification of aberrantly expressed long non-coding RNAs in stomach adenocarcinoma. 324 lncRNA diagnostic biomarker ATB human "tissue,serum" osteosarcoma H original research 28469952 "Long noncoding RNA ATB promotes osteosarcoma cell proliferation, migration and invasion by suppressing miR-200s." 325 lncRNA diagnostic biomarker lnc-IRX3-80 human tissue breast cancer H original research 28469804 Long noncoding RNA CRNDE activates Wnt/β-catenin signaling pathway through acting as a molecular sponge of microRNA-136 in human breast cancer 326 lncRNA diagnostic biomarker "MALAT1,AFAP1-AS1,AL359062" human serum nasopharyngeal cancer "H(MALAT1,AFAP1-AS1)" original research 28467811 "Serum long non-coding RNAs MALAT1, AFAP1-AS1 and AL359062 as diagnostic and prognostic biomarkers for nasopharyngeal carcinoma." 327 lncRNA diagnostic biomarker "NPTN-IT1,PVT1,PANDAR,PTENP1,lINC00963" human uncertain renal cancer "H(PVT1,PANDAR)" original research 28467794 Long non-coding RNAs in renal cell carcinoma: A systematic review and clinical implications. 328 lncRNA diagnostic biomarker lnc-SMIM32-4 human tissue renal cancer clear cell renal cell carcinoma L original research 28450954 "Downregulation of a novel long non-coding RNA, LOC389332, is associated with poor prognosis and tumor progression in clear cell renal cell carcinoma." 329 lncRNA diagnostic biomarker TUG1 human uncertain urothelial cancer H original research 28430799 Diagnostic and prognostic value of long noncoding RNAs as biomarkers in urothelial carcinoma 330 lncRNA diagnostic biomarker "combine(AK001058,INHBA-AS1,MIR4435-2HG,CEBPA-DT)" human tissue，plamsa gastric cancer H original research 28423525 "The combination of circulating long noncoding RNAs AK001058, INHBA-AS1, MIR4435-2HG, and CEBPA-AS1 fragments in plasma serve as diagnostic markers for gastric cancer." 331 lncRNA diagnostic biomarker BLACAT1 human serum colorectal cancer H original research 28406230 "Meta-signature LncRNAs serve as novel biomarkers for colorectal cancer: integrated bioinformatics analysis, experimental validation and diagnostic evaluation." 332 lncRNA diagnostic biomarker "EMP1-008,ATF3-008,RCOR3-013" human tissue cholangio cancer L original research 28401021 Integrated mRNA and lncRNA expression profiling for exploring metastaticbiomarkers of human intrahepatic cholangiocarcinoma. 333 lncRNA diagnostic biomarker MALAT1 human "tissue,cell" osteosarcoma H original research 28388584 MALAT1 predicts poor survival in osteosarcoma patients and promotes cell metastasis through associating with EZH2. 334 lncRNA diagnostic biomarker HOTAIR human serum esophageal cancer esophageal squamous cell carcinoma. H original research 28376832 serum HOTAIR as a novel diagnostic biomarker for esophageal squamous cell carcinoma. 335 lncRNA diagnostic biomarker CYTOR human tissue tongue cancer tongue squamous cell carcinoma H original research 28367232 Upregulated long non-coding RNA LINC00152 expression is associated with progression and poor prognosis of tongue squamous cell carcinoma. 336 lncRNA diagnostic biomarker LINC00312 human tissue，plamsa lung cancer non-small cell lung cancer H original research 28338293 Long non-coding RNA 00312 regulated by HOXA5 inhibits tumour proliferation and promotes apoptosis in Non-small cell lung cancer. 337 lncRNA diagnostic biomarker GAS5 human "tissue,cell" glioma H review 28293170 An Insight into the Increasing Role of LncRNAs in the Pathogenesis of Gliomas 338 lncRNA diagnostic biomarker ZFAS1 human "tissue,serum,cell" gastric cancer H original research 28285404 Exosomes-mediated transfer of long noncoding RNA ZFAS1 promotes gastric cancerprogression. 339 lncRNA diagnostic biomarker lnc-IRX3-80 human cell myeloma multiple myeloma uncertain original research 28276319 Long Noncoding RNA CRNDE Promotes Multiple Myeloma Cell Growth by Suppressing miR-451 340 lncRNA diagnostic biomarker CXCL12 human uncertain thyroid cancer papillary thyroid cancer L original research 28272462 CXCL12 methylation-mediated epigenetic regulation of gene expression in papillary thyroid carcinoma. 341 lncRNA diagnostic biomarker PVT1 human "tissue,serum" melanoma H original research 28265576 Long Noncoding RNA PVT1 as a Novel diagnostic Biomarker and Therapeutic Targetfor Melanoma. 342 lncRNA diagnostic biomarker UBC1 human tissue colorectal cancer H original research 28260919 "Overexpression of the long non-coding RNA, linc-UBC1, is associated with poor prognosis and facilitates cell proliferation, migration, and invasion in colorectal cancer" 343 lncRNA diagnostic biomarker PVT1 human tissue gastric cancer H original research 28258379 "Long Noncoding RNA PVT1 Acts as a ""Sponge"" to Inhibit microRNA-152 in Gastric Cancer Cells." 344 lncRNA diagnostic biomarker "CDKN2B-AS1,HIF1A-AS2,UCA1" human plasma breast cancer triple-negative and non-triple-negative breast cancers H original research 28248879 A three-long noncoding RNA signature as a diagnostic biomarker for differentiating between triple-negative and non-triple-negative breast cancers 345 lncRNA diagnostic biomarker LINC0086 human "tissue,serum" nasopharyngeal cancer uncertain original research 28245169 Long Noncoding RNA LINC0086 Functions as a Tumor Suppressor in Nasopharyngeal Carcinoma by Targeting miR-214. 346 lncRNA diagnostic biomarker SNHG12 human tissue colorectal cancer H original research 28225893 LncRNA SNHG12 promotes cell growth and inhibits cell apoptosis in colorectal cancer cells. 347 lncRNA diagnostic biomarker AGAP2-AS1 human "tissue,cell" gastric cancer H original research 28209205 Long noncoding AGAP2-AS1 is activated by SP1 and promotes cell proliferation and invasion in gastric cancer 348 lncRNA diagnostic biomarker FAM83H-AS1 human tissue lung cancer H original research 28198463 Overexpression of FAM83H-AS1 indicates poor patient survival and knockdown impairs cell proliferation and invasion via MET/EGFR signaling in lung cancer. 349 lncRNA diagnostic biomarker "LINC01811,ENST00000609220,KIAA1755-5:9,B3GALT5-AS1,lnc-FOXB2-9,lnc-FOXB2-9,HOTAIR" human uncertain colon cancer H original research 28160106 Variable Levels of Long Noncoding RNA Expression in DNA Mismatch Repair-Proficient Early-Stage Colon Cancer 350 lncRNA diagnostic biomarker lnc-FGF1-9 human "tissue,cell" ovarian cancer H original research 28129625 Upregulation of the long non-coding RNA SPRY4-IT1 indicates a poor prognosis and promotes tumorigenesis in ovarian cancer. 351 lncRNA diagnostic biomarker RP11-19P22.6-001 human tissue gastric cancer L original research 28128738 Clinical significance of the long noncoding RNA RP11-19P22.6-001 in gastriccancer. 352 lncRNA diagnostic biomarker NKILA human tissue melanoma L original research 28123845 The long non-coding RNA NKILA inhibits the invasion-metastasis cascade of malignant melanoma via the regulation of NF-?B. 353 lncRNA diagnostic biomarker NEAT1 human uncertain digestive system cancer digestive tract cancer L original research 28118609 The clinical value of lncRNA NEAT1 in digestive system malignancies: A comprehensive investigation based on 57 microarray and RNA-seq datasets. 354 lncRNA diagnostic biomarker "lnc-USP6NL-7,CASC2" human uncertain lung cancer lung squamous cell carcinoma "L(SFTA1P,CASC2)" original research 28118064 Co-expression network analysis of long noncoding RNAs (IncRNAs) and cancer genes revealsSFTA1P and CASC2abnormalities in lung squamous cell carcinoma. 355 lncRNA diagnostic biomarker FTX human tissue glioma H original research 28112756 Long noncoding RNA FTX is upregulated in gliomas and promotes proliferation andinvasion of glioma cells by negatively regulating miR-342-3p. 356 lncRNA diagnostic biomarker MALAT1 human uncertain glioma H review 28107175 Long non-coding RNAs: potential molecular biomarkers for gliomas diagnosis and prognosis 357 lncRNA diagnostic biomarker GACAT2 human plasma gastric cancer H original research 28105191 Plasma lncRNA-GACAT2 is a valuable marker for the screening of gastric cancer. 358 lncRNA diagnostic biomarker HOTTIP human tissue lung cancer lung squamous cell carcinoma H(PLAC1) original research 28076325 Identification of long noncoding RNAs for the detection of early stage lung squamous cell carcinoma by microarray analysis 359 lncRNA diagnostic biomarker "lnc-TINCR-1,lnc-MGAT1-4,AOC4P,BANCR,LINC00857" human tissue，plamsa gastric cancer L original research 28042329 Genome-Wide lncRNA Microarray Profiling Identifies Novel Circulating lncRNAs for Detection of Gastric Cancer. 360 lncRNA diagnostic biomarker UCA1 human urine bladder cancer H original research 28038452 Inhibition of long non-coding RNA UCA1 by CRISPR/Cas9 attenuated malignant phenotypes of bladder cancer. 361 lncRNA diagnostic biomarker "ENST00000462717,ENST00000415582,lnc-TK2-5,lnc-LYRM2-2" human plasma thyroid cancer papillary thyroid cancer uncertain original research 27997908 Circulating Long Non-Coding RNAs Act as Biomarkers for Predicting 131I Uptake andMortality in Papillary Thyroid Cancer Patients with Lung Metastases. 362 lncRNA diagnostic biomarker NNT-AS1 nude mice tissue colorectal cancer H original research 27966450 "Upregulated NNT-AS1, a long noncoding RNA, contributes to proliferation and migration of colorectal cancer cells in vitro and in vivo." 363 lncRNA diagnostic biomarker "combine(FR034838342,AK024556,lnc-SPATA31A6-60,LOC100287482,LINC01564,lnc-RPP30-2,lnc-HNF1A-1,HOTAIR,HOX-AS2,MALAT1,LINC-RoR,HOTAIR,lnc-DLK1-35,lnc-FOXB2-9,PVT1,PCAT1,UCA1)" human uncertain;uncertain;urine;tissue;tissue;uncertain;urine uncertain Multiple cancers "H(HOTAIR,MALAT1,PVT1,UCA1,lnc-FOXB2-9)" review 27925173 Potential of long non-coding RNAs in cancer patients: From biomarkers totherapeutic targets. 364 lncRNA diagnostic biomarker DANCR human tissue，plamsa hepatocellular cancer H original research 27919960 DANCR Acts as a diagnostic Biomarker and Promotes Tumor Growth and Metastasis in Hepatocellular Carcinoma. 365 lncRNA diagnostic biomarker lnc-ABCA12-8 human tissue thyroid cancer papillary thyroid cancer H(NONHSAT 076754) original research 27906682 NONHSAT076754 aids ultrasonography in predicting lymph node metastasis and promotes migration and invasion of papillary thyroid cancer cells. 366 lncRNA diagnostic biomarker "Brm,YAP1" human uncertain hepatocellular cancer H original research 27905400 LncBRM initiates YAP1 signalling activation to drive self-renewal of liver cancer stem cells. 367 lncRNA diagnostic biomarker lnc-DGCR6-6 human tissue hepatocellular cancer L original research 27898409 Down-Regulation of LncRNA DGCR5 Correlates with Poor Prognosis in Hepatocellular Carcinoma. 368 lncRNA diagnostic biomarker CRNDE-h human serum colorectal cancer H original research 27888803 Exosomal long noncoding RNA CRNDE-h as a novel serum-based biomarker for diagnosis and prognosis of colorectal cancer. 369 lncRNA diagnostic biomarker ZFAS1 human tissue，cell，plamsa colon cancer "H(ZFAS1,ZEB1)" original research 27862275 Long non-coding ribonucleic acid zinc finger antisense 1 promotes the progression of colonic cancer by modulating ZEB1 expression. 370 lncRNA diagnostic biomarker "FER1L4,lnc-PTGFR-1,UCA1,AFAP1-AS1" human tissue lung cancer non small cell lung cancer "H(UCA1,AFAP1-AS1)" original research 27826625 Integrated analysis of long non-coding RNA?associated ceRNA network revealspotential lncRNA biomarkers in human lung adenocarcinoma. 371 lncRNA diagnostic biomarker AK026659 human tissue colorectal cancer L original research 27788162 "Mining, Validation, and Clinical Significance of Colorectal Cancer (CRC)-Associated lncRNAs." 372 lncRNA diagnostic biomarker PVT1 human serum cervical cancer H original research 27775803 Long noncoding RNA PVT1 as a novel serum biomarker for detection of cervical cancer 373 lncRNA diagnostic biomarker RP1130-1 human tissue hepatocellular cancer L original research 27773892 The significance of low levels of LINC RP1130-1 expression in human hepatocellular carcinoma. 374 lncRNA diagnostic biomarker LINC-PINT human plasma pancreatic cancer L original research 27708234 Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer 375 lncRNA diagnostic biomarker UCA1 human uncertain urinary cancer "prostate cancer, bladder cancer and kidney cancer" H review 27698924 Long Non-coding RNAs in Urologic Malignancies: Functional Roles and ClinicalTranslation 376 lncRNA diagnostic biomarker "combine(TUSC7,RPL34-AS1,lnc-PRCD-5)" human serum colorectal cancer "H(LOC285194,RP11-462C24.1,Nbla12061)" original research 27683121 "Long non-coding RNAs LOC285194, RP11-462C24.1 and Nbla12061 in serum provide a new approach for distinguishing patients with colorectal cancer from healthy controls." 377 lncRNA diagnostic biomarker MIR210HG human tissue glioma H original research 27673330 Long Noncoding RNA miR210HG as a Potential Biomarker for the Diagnosis of Glioma. 378 lncRNA diagnostic biomarker CPS1-IT1 human cell lung cancer H original research 27662619 Long Noncoding RNA CPS1-IT1 Suppresses Cell Proliferation and Metastasis in Human Lung cancer. 379 lncRNA diagnostic biomarker ZFAS1 human "plasma,tissue" gastric cancer H original research 27654478 Increased expression of long-noncoding RNA ZFAS1 is associated withepithelial-mesenchymal transition of gastric cancer. 380 lncRNA diagnostic biomarker lnc-FAM84B-15 human uncertain uncertain H review 27638771 CCAT1: an oncogenic long noncoding RNA in human cancers. 381 lncRNA diagnostic biomarker GAS5 human plasma lung cancer non small cell lung cancer H original research 27631209 Circulating long noncoding RNA GAS5 is a novel biomarker for the diagnosis of nonsmall cell lung cancer. 382 lncRNA diagnostic biomarker "AFAP1-AS1,UCA1,lnc-CELA3A-5" human cell pancreatic cancer pancreatic ductal adenocarcinoma "H(AFAP1-AS1,UCA1)" original research 27628540 Analysis of long non-coding RNA expression profiles in pancreatic ductal adenocarcinomaa 383 lncRNA diagnostic biomarker "BANCR,lnc-CD46-4,LEF1-AS1,LINC00460" human "tissue,serum" colorectal cancer "H(BANCR,LINC00460)" original research 27591862 Identification of long noncoding RNAs as potential novel diagnosis and prognosis biomarkers in colorectal cancer. 384 lncRNA diagnostic biomarker NEAT1 human "stool,plasma,serum" colorectal cancer H review 27573899 Non-coding RNAs as Biomarkers for Colorectal Cancer Screening and Early Detection. 385 lncRNA diagnostic biomarker CDKN2B-AS1 human uncertain nasopharyngeal cancer H original research 27557514 "LncRNA ANRIL is up-regulated in nasopharyngeal carcinoma and promotes the cancer progression via increasing proliferation, reprograming cell glucose metabolismand inducing side-population stem-like cancer cells" 386 lncRNA diagnostic biomarker "SCHLAP1,PCGEM1,lnc-FOXB2-9" human cell prostate cancer H original research 27556357 Identification of androgen-responsive lncRNAs as diagnostic and prognosticmarkers for prostate cancer. 387 lncRNA diagnostic biomarker H19 human plasma breast cancer H original research 27540977 Circulating lncRNA H19 in plasma as a novel biomarker for breast cancer 388 lncRNA diagnostic biomarker lnc-FOXB2-9 human uncertain uncertain H review 27535639 "NON-CODING RNAs IN DEVELOPMENT AND DISEASE: BACKGROUND, MECHANISMS, AND THERAPEUTIC APPROACHES" 389 lncRNA diagnostic biomarker MALAT1 human uncertain renal cancer H original research 27527868 LncRNAs act as prognostic and diagnostic biomarkers in renal cell carcinoma: a systematic review and meta-analysis.g 390 lncRNA diagnostic biomarker NR_036575.1 human "tissue,cell" thyroid cancer papillary thyroid carcinoma H original research 27510368 Overexpression of long non-coding RNA NR_036575.1 contributes to the proliferation and migration of papillary thyroid cancer. 391 lncRNA diagnostic biomarker "combine(PVT1,MIR7-3HG)" human serum hepatocellular cancer H(PVT1) original research 27495068 The long noncoding RNAs PVT1 and uc002mbe.2 in sera provide a new supplementary method for hepatocellular carcinoma diagnosis. 392 lncRNA diagnostic biomarker "HOTTIP-005,LINC02041,MALAT1" human cell pancreatic cancer H(MALAT1) original research 27487139 Construction and analysis of dysregulated lncRNA-associated ceRNA network identified novel lncRNA biomarkers for early diagnosis of human pancreatic cancer. 393 lncRNA diagnostic biomarker CTNNAP1 human uncertain uncertain L original research 27487124 Downregulated pseudogene CTNNAP1 promote tumor growth in human cancer bydownregulating its cognate gene CTNNA1 expression. 394 lncRNA diagnostic biomarker lnc-GSDMC-34 human tissue pancreatic cancer H original research 27470572 Long noncoding RNA CCDC26 as a potential predictor biomarker contributes to tumorigenesis in pancreatic cancer 395 lncRNA diagnostic biomarker P2RX7-V3 human uncertain melanoma uveal melanoma H original research 27468714 P2RX7-V3 is a novel oncogene that promotes tumorigenesis in uveal melanoma 396 lncRNA diagnostic biomarker MALAT1 human serum breast cancer H original research 27466303 Clinical Significance of Long Non-coding RNA MALAT1 Expression in Tissue and Serum of Breast Cancer. 397 lncRNA diagnostic biomarker "combine(AK001094,AK024171,AK093735,BC003519,NR_003573)" human tissue gastric cancer uncertain original research 27460075 Identification of a five-lncRNA signature for the diagnosis and prognosis of gastric cancer 398 lncRNA diagnostic biomarker PICSAR human uncertain cutaneous cancer cutaneous squamous cell carcinoma L review 27450499 PICSAR: Long Noncoding RNA in Cutaneous Squamous Cell Carcinoma. 399 lncRNA diagnostic biomarker ZFP91-P human cell pancreatic cancer H original research 27446435 Inhibitory effect of RNA-mediated knockdown of zinc finger protein 91 pseudogene on pancreatic cancer cell growth and invasion. 400 lncRNA diagnostic biomarker MALAT1 human tissue pancreatic cancer H original research 27371730 Long Noncoding RNA MALAT1 Promotes Aggressive Pancreatic Cancer Proliferation and Metastasis via the Stimulation of Autophagy. 401 lncRNA diagnostic biomarker "lnc-MUC20-68,XLOC_l2_004121,XLOC_l2_004340,XLOC_l2_007509,XLOC_l2_009441,XLOC_l2_013931" human tissue pan-cancer uncertain original research 27322459 "Pan-Cancer Analyses Reveal Long Intergenic Non-Coding RNAs Relevant to Tumor diagnosis, Subtyping and prognosis." 402 lncRNA diagnostic biomarker lnc-BMP6-106 human serum gastric cancer H original research 27322075 Long non-coding RNA HULC as a novel serum biomarker for diagnosis and prognosis prediction of gastric cancer. 403 lncRNA diagnostic biomarker HOTAIRM1 human tissue，plamsa colorectal cancer L original research 27307307 HOTAIRM1 as a potential biomarker for diagnosis of colorectal cancer functions the role in the tumour suppressor. 404 lncRNA diagnostic biomarker UCA1 human serum hepatocellular cancer H original research 27215316 Association of long noncoding RNA and c-JUN expression in hepatocellularcarcinoma 405 lncRNA diagnostic biomarker "UCA1,PTENP1,H19,MALAT1,lnc-BMP6-106" human serum colorectal cancer "H(MALAT1,H19,UCA1)" original research 27197301 Circulating Long RNAs in Serum Extracellular Vesicles: Their Characterization and Potential Application as Biomarkers for Diagnosis of Colorectal Cancer. 406 lncRNA diagnostic biomarker lnc-PERP-2 human tissue gastric cardia cancer gastric cardia adenocancer L original research 27189370 Methylation-mediated downregulation of long noncoding RNA LOC100130476 in gastriccardia adenocarcinoma. 407 lncRNA diagnostic biomarker "MALAT1,combine(lnc-RC3H1-1,lnc-RGL4-4,LOC149086),AF085935,H19" human serum uncertain "H(MALAT1,H19)" review 27189224 Circulating long non-coding RNAs in cancer: current status and futureperspectives 408 lncRNA diagnostic biomarker H19 human plasma gastric cancer H original research 27184562 Evaluation of the Role of Circulating Long Non-Coding RNA H19 as a Promising Novel Biomarker in plasma of Patients with Gastric cancer. 409 lncRNA diagnostic biomarker HOTAIR human tissue ovarian cancer epithelial ovarian cancer H original research 27166268 Genetic variants of lncRNA HOTAIR and risk of epithelial ovarian cancer among Chinese women. 410 lncRNA diagnostic biomarker LOC572558 human tissue bladder cancer H original research 27130667 Long non-coding RNA LOC572558 inhibits bladder cancer cell proliferation and tumor growth by regulating the AKT-MDM2-p53 signaling axis 411 lncRNA diagnostic biomarker lnc-BMP6-106 human tissue lymphoma diffuse large B-cell lymphoma L original research 27044827 Long noncoding RNA HULC predicts poor clinical outcome and represents pro-oncogenic activity in diffuse large B-cell lymphoma. 412 lncRNA diagnostic biomarker "HOTAIR,PVT1" human saliva pancreatic cancer H original research 27028998 Salivary HOTAIR and PVT1 as novel biomarkers for early pancreatic cancer. 413 lncRNA diagnostic biomarker H19 human serum uncertain Multiple cancers H review 27017010 Role of Long Noncoding RNAs in Neoplasia: Special Emphasis on Prostate Cancer. 414 lncRNA diagnostic biomarker CASC11 human tissue colorectal cancer H original research 27012187 Long non-coding RNA CASC11 interacts with hnRNP-K and activates the WNT/β-catenin pathway to promote growth and metastasis in colorectal cancer 415 lncRNA diagnostic biomarker UCA1 human plasma acute myocardial infarction "bladder cancer, lung cancer" H original research 26949706 Circulating Long Noncoding RNA UCA1 as a Novel Biomarker of Acute Myocardial Infarction. 416 lncRNA diagnostic biomarker UCA1 human tissue renal cancer H original research 26935146 Identification of long-non coding RNA UCA1 as an oncogene in renal cell carcinoma 417 lncRNA diagnostic biomarker "ATP8B5P,FOXD2-AS1,GUCY1B2,H19,HOTAIR,LOC100128164,SNORD116-4,LOC553137,PART1,lnc-ANKRD20A2-1,PVT1,RHPN1-AS1,RPLP0P2,SLC26A4-AS1,SMIM10L2A,lnc-SMIM10L2B-1,lnc-TINCR-1,TSPEAR-AS2,UCA1" human uncertain gastric cancer "H(H19,HOTAIR,UCA1,PVT1)" original research 26935047 Integrated analysis of long non-coding RNA competing interactions reveals thepotential role in progression of human gastric cancer. 418 lncRNA diagnostic biomarker PVT1 human tissue gastric cancer H original research 26925791 Aberrant expression of long noncoding RNA PVT1 and its diagnostic and prognostic significance in patients with gastric cancer. 419 lncRNA diagnostic biomarker "lnc-MAST4-5,LINC00052,BC016831,IGKV" human tissue breast cancer triple negative breast cancer uncertain original research 26910840 LncRNAs as new biomarkers to differentiate triple negative breast cancer from non-triple negative breast cancer. 420 lncRNA diagnostic biomarker "BANCR,lnc-MGAT1-4,MALAT1" human uncertain lung cancer non small cell lung cancer "H(BANCR,MALAT1)" original research 26903166 [Progress of Long Non-coding RNAs in Non-small Cell Lung Cancer]. 421 lncRNA diagnostic biomarker LINC01852 human tissue lung cancer non small cell lung cancer L original research 26883250 Long noncoding RNA ENST00000434223 suppressed tumor progression in non-small cell lung cancer. 422 lncRNA diagnostic biomarker "combine(lnc-PLET1-1,PVT1,PANDAR,PTENP1,LINC00963)" human serum renal cancer clear cell renal cell carcinoma "H(PVT1,PANDAR)" original research 26878386 A serum-circulating long noncoding RNA signature can discriminate between patients with clear cell renal cell carcinoma and healthy controls. 423 lncRNA diagnostic biomarker KRT18P55 human tissue gastric cancer H original research 26855593 Upregulated long intergenic noncoding RNA KRT18P55 acts as a novel biomarker for the progression of intestinal-type gastric cancer. 424 lncRNA diagnostic biomarker lnc-EMX1-1 human tissue prostate cancer H original research 26797523 Long non-coding RNA lnc-MX1-1 is associated with poor clinical features and promotes cellular proliferation and invasiveness in prostate cancer. 425 lncRNA diagnostic biomarker lnc-IGF1R-1 human "tissue,cell" lymphoma diffuse large B-cell lymphoma H original research 26796267 Long noncoding RNA LUNAR1 associates with cell proliferation and predicts a poor prognosis in diffuse large B-cell lymphoma 426 lncRNA diagnostic biomarker "MALAT1,lnc-MGAT1-4" human uncertain lung cancer non-small cell lung cancer H(MALAT1) review 26786153 "Long noncoding RNAs: new insights into non-small cell lung cancer biology,diagnosis and therapy." 427 lncRNA diagnostic biomarker H19 human "tissue,cell,gastric juice" gastric cancer H original research 26774144 H19 serves as a diagnostic biomarker and up-regulation of H19 expressioncontributes to poor prognosis in patients with gastric cancer. 428 lncRNA diagnostic biomarker CDKN2B-AS1 human uncertain uncertain Multiple cancers H review 26753962 ANRIL: a pivotal tumor suppressor long non-coding RNA in human cancers. 429 lncRNA diagnostic biomarker UCA1 human plasma gastric cancer H original research 26722487 Long non-coding RNA UCA1 may be a novel diagnostic and predictive biomarker in plasma for early gastric cancer. 430 lncRNA diagnostic biomarker "CTD-2541M15,UCA1,AP000459,TUSC8,lnc-DLK1-35" human tissue gastric cancer H(UCA1) original research 26718650 Differential expression profiles of long non-coding RNAs reveal potential biomarkers for identification of human gastric cancer 431 lncRNA diagnostic biomarker HOTAIR human cell nasopharyngeal cancer H original research 26717040 Long noncoding RNA Hotair mediated angiogenesis in nasopharyngeal carcinoma by direct and indirect signaling pathways. 432 lncRNA diagnostic biomarker "HOTAIRM1,HOTAIR,lnc-BMP6-106,GAS5" human tissue pancreatic cancer pancreatic ductal adenocarcinoma "H(HOTAIR,GAS5)" original research 26676849 Microarray expression profile analysis of long non-coding RNAs in pancreaticductal adenocarcinoma. 433 lncRNA diagnostic biomarker "uc001ncr,AX800134" human serum hepatocellular cancer H original research 26674525 Serum LncRNAs Profiles Serve as Novel Potential Biomarkers for the Diagnosis of HBV-Positive Hepatocellular Carcinoma. 434 lncRNA diagnostic biomarker lnc-FAM84B-15 human tissue hepatocellular cancer uncertain review 26668690 Long noncoding RNAs in hepatocellular carcinoma: Novel insights into their mechanism 435 lncRNA diagnostic biomarker "combine(UCA1,LSINCT-5,PTENP1,POU3F3)" human serum;plasma breast cancer H(UCA1) original research 26662314 Circulating long noncoding RNA GAS5 as a potential biomarker in breast cancer for assessing the surgical effects. 436 lncRNA diagnostic biomarker SNHG15 human "tissue,cell" gastric cancer H original research 26662309 Upregulated expression of long noncoding RNA SNHG15 promotes cell proliferation and invasion through regulates MMP2/MMP9 in patients with GC 437 lncRNA diagnostic biomarker "HOTAIR,MALAT1" human uncertain colorectal cancer H review 26637808 Long non-coding RNAs in colorectal cancer 438 lncRNA diagnostic biomarker GAS5 human uncertain uncertain Multiple cancers H review 26634743 The growth arrest-specific transcript 5 (GAS5): a pivotal tumor suppressor long noncoding RNA in human cancers. 439 lncRNA diagnostic biomarker lnc-RPS6KL1-1 human "tissue,cell" thyroid cancer papillary thyroid cancer L original research 26611646 Downregulation of long noncoding RNA NONHSAT037832 in papillary thyroid carcinoma and its clinical significance. 440 lncRNA diagnostic biomarker "H19,UCA1" human plasma uncertain H review 26608368 Influence of the interaction between long noncoding RNAs and hypoxia on tumorigenesis 441 lncRNA diagnostic biomarker lnc-ITGB1-6 human tissue breast cancer H original research 26601916 Long noncoding RNA linc-ITGB1 promotes cell migration and invasion in human breast cancer. 442 lncRNA diagnostic biomarker HOTAIR human uncertain breast cancer H review 26582840 Long noncoding RNAs in regulation of human breast cancer. 443 lncRNA diagnostic biomarker "UCA1,WRAP53" human serum hepatocellular cancer "H(lncRNA-UCA1,lncRNA-WRAP53)" original research 26551349 Investigation of long noncoding RNAs expression profile as potential serum biomarkers in patients with hepatocellular carcinoma. 444 lncRNA diagnostic biomarker "LINC01419,AK021443,AF070632" human tissue hepatocellular cancer "H(LINC01419,AK021443),L(AF070632)" original research 26540467 Long non-coding RNA expression profiles of hepatitis C virus-related dysplasia and hepatocellular carcinoma. 445 lncRNA diagnostic biomarker PRNCR1 human "tissue,cell" colorectal cancer H original research 26530130 Upregulation of long non-coding RNA PRNCR1 in colorectal cancer promotes cellproliferation and cell cycle progression. 446 lncRNA diagnostic biomarker "AF085935,combine(lnc-RC3H1-1,lnc-RGL4-4,LOC149086)" human "tissue,cell" uncertain uncertain review 26516918 The Clinical Relevance of Long Non-Coding RNAs in Cancer. 447 lncRNA diagnostic biomarker "MALAT1,lnc-FOXB2-9,PCATs,SCHLAP1,lnc-FGF1-9,TRPM2-AS" human uncertain prostate cancer H review 26503110 Clinical prospects of long noncoding RNAs as novel biomarkers and therapeutic targets in prostate cancer. 448 lncRNA diagnostic biomarker lnc-FGF1-9 human "tissue,cell" glioma H original research 26464658 "Knockdown of long noncoding RNA SPRY4-IT1 suppresses glioma cell proliferation, metastasis and epithelial-mesenchymal transition." 449 lncRNA diagnostic biomarker "CA125,CYFRA21-1" human plasma lung cancer non-small-cell lung cancer "H(SPRY4-IT1,ANRIL,NEAT1)" original research 26453113 The plasma lncRNA acting as fingerprint in non-small-cell lung cancer. 450 lncRNA diagnostic biomarker "HOTTIP-005,LINC02041" human plasma pancreatic cancer "H(HOTTIP-005,RP11-567G11.1)" original research 26447755 Expression profile of long non-coding RNAs in pancreatic cancer and theirclinical significance as biomarkers. 451 lncRNA diagnostic biomarker "combine(LINC01627,LINC01628,ERICH1-AS1)" human blood lung cancer non small cell lung cancer "H(RP11-397D12.4,AC007403.1,ERICH1-AS1)" original research 26393913 Three circulating long non-coding RNAs act as biomarkers for predicting NSCLC. 452 lncRNA diagnostic biomarker UCA1 human plasma lung cancer H original research 26380024 Upregulated lncRNA-UCA1 contributes to progression of lung cancer and is closely related to clinical diagnosis as a predictive biomarker in plasma. 453 lncRNA diagnostic biomarker "combine(UCA1,LSINCT-5,PTENP1)" human uncertain gastric cancer H(UCA1) review 26379393 Circulating microRNAs and long non-coding RNAs in gastric cancer diagnosis: An update and review 454 lncRNA diagnostic biomarker "lnc-BMP6-106,CYTOR" human plasma hepatocellular cancer "H(HULC,Linc00152)" original research 26356260 HULC and Linc00152 Act as Novel Biomarkers in Predicting diagnosis ofHepatocellular carcinoma. 455 lncRNA diagnostic biomarker UCA1 human tissue uncertain H review 26341664 Urothelial cancer associated 1: a long noncoding RNA with a crucial role in cancer. 456 lncRNA diagnostic biomarker "combine(XIST,HIF1A-AS1)" human "tissue，plamsa,serum" lung cancer non-small-cell lung cancer "H(XIST,HIF1A-AS1)" original research 26339353 Combined identification of long non-coding RNA XIST and HIF1A-AS1 in serum as an effective screening for non-small cell lung cancer. 457 lncRNA diagnostic biomarker TUG1 human tissue hepatocellular cancer H original research 26336870 Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2. 458 lncRNA diagnostic biomarker LINC00982 human tissue gastric cancer H original research 26334618 Upregulated expression of long non-coding RNA LINC00982 regulates cell proliferation and its clinical relevance in patients with gastric cancer. 459 lncRNA diagnostic biomarker "GAS5,GAS6-AS1,H19" human cell lung cancer H review 26332907 Long non-coding RNA: A new paradigm for lung cancer. 460 lncRNA diagnostic biomarker lncRNA40057 human tissue cholangio cancer intrahepatic cholangiocarcinoma L original research 26297049 Coding-noncoding gene expression in intrahepatic cholangiocarcinoma. 461 lncRNA diagnostic biomarker "MALAT1,HOTAIR" human cell gastric cancer H original research 26291830 Multidrug-Resistance Related Long Non-Coding RNA Expression Profile Analysis of Gastric Cancer. 462 lncRNA diagnostic biomarker "lnc-FAM84B-15,lnc-BUD23-1" human tissue gastric cancer H original research 26280398 Using gastric juice lncRNA-ABHD11-AS1 as a novel type of biomarker in the screening of gastric cancer. 463 lncRNA diagnostic biomarker KCNQ1OT1 human uncertain colorectal cancer uncertain original research 26278472 Predicting lncRNA-disease associations and constructing lncRNA functional similarity network based on the information of miRNA. 464 lncRNA diagnostic biomarker lnc-BMP6-106 human uncertain hepatocellular cancer uncertain review 26239319 The role of long non-coding RNAs in hepatitis B virus-related hepatocellular carcinoma. 465 lncRNA diagnostic biomarker CYTOR human cell gastric cancer H original research 26237576 "Long non-coding RNA Linc00152 is involved in cell cycle arrest, apoptosis,epithelial to mesenchymal transition, cell migration and invasion in gastriccancer." 466 lncRNA diagnostic biomarker lnc-SLC25A16-2 human tissue gastric cancer L original research 26170986 Novel long non-coding RNA RP11-119F7.4 as a potential biomarker for the development and progression of gastric cancer. 467 lncRNA diagnostic biomarker "H19,HOTAIR,NCRUPAR,GACAT1,FER1L4,HMLINCRNA717,uc001lsz" human plasma;plasma;uncertain;uncertain digestive system cancer digestive tract cancer "H(H19,HOTAIR,GACAT1)" review 26156325 "Long Noncoding RNA in Digestive Tract Cancers: Function, Mechanism, and PotentialBiomarke" 468 lncRNA diagnostic biomarker lnc-BMP6-106 human uncertain hepatocellular cancer H original research 26143461 A growing number ofevidences indicate that long non-coding RNAs (lncRNAs) have many functions in thedevelopment and progression of breast cancer and may serve as the markers ofdiagnosis or prognosis. 469 lncRNA diagnostic biomarker UCA1 human "urine,blood" bladder cancer H original research 26138586 Integrative functional genetic-epigenetic approach for selecting genes as urine biomarkers for bladder cancer diagnosis 470 lncRNA diagnostic biomarker lnc-FOXB2-9 human uncertain prostate cancer H review 26110379 Circulating Long Noncoding RNA as a Potential Target for Prostate Cancer. 471 lncRNA diagnostic biomarker H19 human plasma gastric cancer H original research 26096073 Identification of the long non-coding RNA H19 in plasma as a novel biomarker for diagnosis of gastric cancer. 472 lncRNA diagnostic biomarker lnc-FOXB2-9 human tissue prostate cancer H(PCA3) original research 26080435 PRUNE2 is a human prostate cancer suppressor regulated by the intronic longnoncoding RNA PCA3. 473 lncRNA diagnostic biomarker lnc-FAM84B-15 human tissue colorectal cancer H original research 26064266 "Expression of lncRNA-CCAT1, E-cadherin and N-cadherin in colorectal cancer and its clinical significance." 474 lncRNA diagnostic biomarker PANDAR human "tissue,cell" hepatocellular cancer H original research 26054684 Long non-coding RNA PANDAR correlates with poor prognosis and promotes tumorigenesis in hepatocellular carcinoma 475 lncRNA diagnostic biomarker lINC00152 human plasma gastric cancer uncertain review 26045977 Long non-coding RNAs in gastric cancer: versatile mechanisms and potential for clinical translation. 476 lncRNA diagnostic biomarker HOTAIR human tissue oral cancer oral squamous cell carcinoma H original research 26036760 Expression of long noncoding RNA-HOX transcript antisense intergenic RNA in oral squamous cell carcinoma and effect on cell growth. 477 lncRNA diagnostic biomarker lnc-FOXB2-9 human tissue prostate cancer H review 26022941 RNA biomarkers to facilitate the identification of aggressive prostate cancer. 478 lncRNA diagnostic biomarker AI364715 human tissue gastric cancer L original research 25971582 Reduced expression of the long non-coding RNA AI364715 in gastric cancer and its clinical significance. 479 lncRNA diagnostic biomarker H19 human uncertain hepatocellular cancer H original research 25968300 Progress and Prospects of Long Noncoding RNAs (lncRNAs) in Hepatocellular Carcinoma 480 lncRNA diagnostic biomarker "HOTAIR,lnc-BMP6-106,lnc-FOXB2-9,PCGEM1,UCA1" human uncertain;plasma;tissue;urine uncertain "H(HOTAIR,UCA1,lnc-FOXB2-9)" review 25954300 Long noncoding RNAs: a potential novel class of cancer biomarkers 481 lncRNA diagnostic biomarker lnc-ADA-3 human serum breast cancer H original research 25929808 Clinical significance of high expression of circulating serum lncRNARP11-445H22.4 in breast cancer patients: a Chinese population-based study. 482 lncRNA diagnostic biomarker GAS5 human cell lung cancer non-small cell lung cancer L original research 25925741 "The long non-coding RNA, GAS5, enhances gefitinib-induced cell death in innate EGFR tyrosine kinase inhibitor-resistant lung adenocarcinoma cells with wide-type EGFR via downregulation of the IGF-1R expression." 483 lncRNA diagnostic biomarker UCA1 human "tissue,cell" gastric cancer H original research 25903045 Aberrant expression of UCA1 in gastric cancer and its clinical significance. 484 lncRNA diagnostic biomarker lnc-POTEM-4 human tissue colorectal cancer H original research 25894381 Long non-coding RNA LINC01296 is a potential prognostic biomarker in patientswith colorectal cancer. 485 lncRNA diagnostic biomarker PEG10 human tissue lymphoma diffuse large B cell lymphoma H original research 25864113 Upregulation of long noncoding RNA PEG10 associates with poor prognosis in diffuse large B cell lymphoma with facilitating tumorigenicity 486 lncRNA diagnostic biomarker HOTAIR human tissue uncertain Multiple cancers H review 25859406 HOTAIR: an oncogenic long non-coding RNA in different cancers. 487 lncRNA diagnostic biomarker H19 human tissue breast cancer H original research 25846769 H19 lncRNA mediates 17β-estradiol-induced cell proliferation in MCF-7 breastcancer cells. 488 lncRNA diagnostic biomarker UBC1 human tissue gastric cancer H original research 25755750 Long noncoding RNA linc-UBC1 is negative prognostic factor and exhibits tumor pro-oncogenic activity in gastric cancer. 489 lncRNA diagnostic biomarker "RP11-58D2.1,LINC01926,lnc-MRPL39-3,lnc-TRIM41-4,CR619813,DDX6P" human uncertain pancreatic cancer uncertain original research 25755691 Genomic analysis of drug resistant pancreatic cancer cell line by combining long non-coding RNA and mRNA expression profling. 490 lncRNA diagnostic biomarker "lnc-FAM84B-15,lnc-IRX3-80,lnc-FOXB2-9,XIST" human uncertain uncertain H(lnc-FOXB2-9) review 25748036 LncRNAs and neoplasia. 491 lncRNA diagnostic biomarker "H19,MALAT1" human uncertain hepatocellular cancer H review 25721084 The emergence of long non-coding RNAs in the tumorigenesis of hepatocellular carcinoma 492 lncRNA diagnostic biomarker "lnc-RGL4-4,LOC149086" human plasma hepatocellular cancer "H(RP11-160H22.5,XLOC_014172,LOC149086)" original research 25714016 Circulation long non-coding RNAs act as biomarkers for predicting tumorigenesis and metastasis in hepatocellular carcinoma. 493 lncRNA diagnostic biomarker "combine(UCA1,LSINCT-5,PTENP1)" human serum gastric cancer H(UCA1) original research 25694351 "Circulating CUDR, LSINCT-5 and PTENP1 long noncoding RNAs in sera distinguish patients with gastric cancer from healthy controls" 494 lncRNA diagnostic biomarker HIF1A-AS2 nude mice tissue gastric cancer H original research 25686741 Antisense Long Noncoding RNA HIF1A-AS2 Is Upregulated in Gastric Cancer and Associated with Poor Prognosis. 495 lncRNA diagnostic biomarker lnc-FOXB2-9 human tissue renal cancer clear cell renal cell carcinoma H original research 25685243 Identification of novel long non-coding RNAs in clear cell renal cell carcinoma. 496 lncRNA diagnostic biomarker LINC02015 human tissue esophageal cancer esophageal squamous cell carcinoma H original research 25677908 Long noncoding RNA CCAT2 correlates with smoking in esophageal squamous cell carcinoma. 497 lncRNA diagnostic biomarker POU3F3 human plasma esophageal cancer esophageal squamous cell carcinoma H original research 25608466 Identification of the long non-coding RNA POU3F3 in plasma as a novel biomarkerfor diagnosis of esophageal squamous cell carcinoma. 498 lncRNA diagnostic biomarker FR0348383 human urine prostate cancer H(AK098081) original research 25597901 A novel urinary long non-coding RNA transcript improves diagnostic accuracy in patients undergoing prostate biopsy. 499 lncRNA diagnostic biomarker MALAT1 human tissue lung cancer non-small cell lung cancer H original research 25590602 Identification and validation of long noncoding RNA biomarkers in humannon-small-cell lung carcinomas. 500 lncRNA diagnostic biomarker MALAT1 human urine prostate cancer H original research 25526029 Development and prospective multicenter evaluation of the long noncoding RNA MALAT-1 as a diagnostic urinary biomarker for prostate cancer 501 lncRNA diagnostic biomarker "combine(PR-lncRNA-1,PR-lncRNA-2,PR-lncRNA-10,PR-lncRNA-17,PR-lncRNA-18)" human uncertain uncertain colorectal cancer L original research 25524025 Genome-wide analysis of the human p53 transcriptional network unveils a lncRNA tumour suppressor signature 502 lncRNA diagnostic biomarker "AA174084,lnc-BUD23-1,GACAT1,GACAT2,GACAT3,H19,lnc-BMP6-106,MALAT1" human tissue;plasma;cell gastric cancer "H(GACAT2,GACAT3,H19,MALAT1)" review 25501508 Focusing on long noncoding RNA dysregulation in gastric cancer 503 lncRNA diagnostic biomarker LINC00974 human plasma hepatocellular cancer H original research 25476897 A novel biomarker Linc00974 interacting with KRT19 promotes proliferation and metastasis in hepatocellular carcinoma. 504 lncRNA diagnostic biomarker "GACAT1,NCRUPAR,AA174084,FER1L4,lnc-RTN2-1,GAS5,GACAT2,GACAT3,CYTOR,lnc-BMP6-106,PVT1,SUMO1P3,lnc-BUD23-1,HOTAIR,GAPLINC" human uncertain gastric cancer "H(GACAT1,GAS5,PVT1,HOTAIR)" review 25444905 Long noncoding RNAs: novel insights into gastric cancer. 505 lncRNA diagnostic biomarker GHET1 human tissue bladder cancer H original research 25400817 Long noncoding RNA GHET1 promotes the development of bladder cancer 506 lncRNA diagnostic biomarker CYTOR human plasma gastric cancer H original research 25391424 Plasma long noncoding RNA protected by exosomes as a potential stable biomarker for gastric cancer. 507 lncRNA diagnostic biomarker lnc-FOXB2-9 human tissue prostate cancer H original research 25307116 Long noncoding RNAs as putative biomarkers for prostate cancer detection 508 lncRNA diagnostic biomarker "ESCCAL_1,HOTAIR" human tissue esophageal cancer esophageal squamous cell carcinoma H original research 25297587 Genome wide screening and characterization of long non-coding RNAs in esophagealcancer 509 lncRNA diagnostic biomarker lnc-RTN2-1 human tissue gastric cancer L original research 25260808 The novel long noncoding RNA AC138128.1 may be a predictive biomarker in gastric cancer. 510 lncRNA diagnostic biomarker PVT1 human "tissue,cell" gastric cancer H original research 25258543 Expression and clinical significance of the long non-coding RNA PVT1 in human gastric cancer. 511 lncRNA diagnostic biomarker "AC026166.2-001,LINC01537" human tissue laryngeal cancer laryngeal squamous cell carcinoma uncertain original research 25243407 Long non-coding RNA profiling in laryngeal squamous cell carcinoma and its clinical significance: potential biomarkers for LSCC. 512 lncRNA diagnostic biomarker lnc-FOXB2-9 human tissue prostate cancer H review 25232225 Function of PCA3 in prostate tissue and clinical research progress on developing a PCA3 score 513 lncRNA diagnostic biomarker AA174084 human tissue，plamsa gastric cancer L original research 24986041 Gastric juice long noncoding RNA used as a tumor marker for screening gastriccancer 514 lncRNA diagnostic biomarker lnc-BUD23-1 human tissue gastric cancer H original research 24984296 Increased expression of long noncoding RNA ABHD11-AS1 in gastric cancer and itsclinical significance. 515 lncRNA diagnostic biomarker RPL34-AS1 human tissue colorectal cancer L original research 24908062 Low expression of novel lncRNA RP11-462C24.1 suggests a biomarker of poor prognosis in colorectal cancer. 516 lncRNA diagnostic biomarker "CYTOR,p21,ZFAS1" human tissue lung cancer non-small cell lung cancer uncertain original research 24906504 Analysis of lncRNA expression profiles in non-small cell lung cancers (NSCLC) and their clinical subtypes. 517 lncRNA diagnostic biomarker MALAT1 human cell gastric cancer H original research 24857172 MALAT1 promotes cell proliferation in gastric cancer by recruiting SF2/ASF. 518 lncRNA diagnostic biomarker HOTAIR human tissue cervical cancer H original research 24748337 Overexpression of long noncoding RNA HOTAIR predicts a poor prognosis in patients with cervical cancer. 519 lncRNA diagnostic biomarker UCA1 human uncertain bladder cancer H original research 24737584 "Urothelial carcinoma associated 1 is a hypoxia-inducible factor-1α-targeted long noncoding RNA that enhances hypoxic bladder cancer cell proliferation, migration, and invasion." 520 lncRNA diagnostic biomarker CYTOR human tissue gastric cancer H original research 24523021 Increased expression of long intergenic non-coding RNA LINC00152 in gastriccancer and its clinical significance. 521 lncRNA diagnostic biomarker LINC02015 human tissue lung cancer non-small cell lung cancer H original research 24504682 CCAT2 is a lung adenocarcinoma-specific long non-coding RNA and promotes invasionof non-small cell lung cancer. 522 lncRNA diagnostic biomarker RERT human uncertain hepatocellular cancer uncertain review 24493213 Long non-coding RNA in liver diseases 523 lncRNA diagnostic biomarker lnc-BMP6-106 human uncertain hepatocellular cancer uncertain review 24296588 Characteristics of long non-coding RNA and its relation to hepatocellular carcinoma. 524 lncRNA diagnostic biomarker lnc-BMP6-106 human tissue gastric cancer H(HULC) original research 24247585 "Role of long non-coding RNA HULC in cell proliferation, apoptosis and tumor metastasis of gastric cancer: a clinical and in vitro investigation." 525 lncRNA diagnostic biomarker uc001lsz human serum gastric cancer L original research 24063685 Long non-coding RNA expression profile in human gastric cancer and its clinicalsignificances. 526 lncRNA diagnostic biomarker SUMO1P3 human tissue gastric cancer H original research 23996296 Up-regulation of SUMO1 pseudogene 3 (SUMO1P3) in gastric cancer and its clinical association. 527 lncRNA diagnostic biomarker lnc-BMP6-106 human plasma hepatocellular cancer H original research 23762823 Plasma HULC as a Promising Novel Biomarker for the Detection of Hepatocellular Carcinoma 528 lncRNA diagnostic biomarker GACAT1 human tissue gastric cancer L(AC096655.1-002) original research 23645148 Decreased expression of long noncoding RNA AC096655.1-002 in gastric cancer and its clinical significance. 529 lncRNA diagnostic biomarker HOTAIR human saliva oral cancer oral squamous cell carcinoma H original research 23292713 Salivary lncRNA as a potential marker for oral squamous cell carcinoma diagnosis 530 lncRNA diagnostic biomarker lnc-FOXB2-9 human "urine,serum" uncertain H original research 22408643 Perspectives of Long Non-Coding RNAs in Cancer Diagnostics.