No. Biomarker_type Function_type Biomarker_symbol Species Tissue_or_sample Cancer_type Cancer_subtype Expression(Adverse risk) Reference type PMID Article_title 1 mRNA diagnostic biomarker CD274 human tissue "lung cancer,head and neck cancer" "non-small cell lung cancer,head and neck squamous cell carcinoma" H review 30986253 "Assessment of PD-L1 mRNA and protein expression in non-small cell lung cancer, head and neck squamous cell carcinoma and urothelial carcinoma tissue specimens using RNAScope and immunohistochemistry." 2 mRNA diagnostic biomarker TSHR human blood thyroid cancer H original research 30984519 Determining Specific Thyroid Transcripts in Peripheral Blood: A Single Center Study Experience. 3 mRNA diagnostic biomarker "NID2,COL4A1,COL4A2" human tissue gastric cancer H original research 30975489 Integrated bioinformatics analysis reveals novel key biomarkers and potential candidate small molecule drugs in gastric cancer. 4 mRNA diagnostic biomarker "NPEPPS,TMPRSS2,ERG,AR,AKR1C3,ANGPTL4,CCL2,CLDN3,CRP,EGFR,EN2,GOAT,HOXB13,OLFM4,PPM1D,PSCA,PSGR,PTK7,SPINK1,SPON2,TDRD1,TFF3,TK1,TRPM4,PTEN,CLU,AZGP1,PSF1,CCL11,SOX2,ARSB,MAGI2,SLC18A2,ADAM19,EFEMP1,SFRP1,PBX3" human uncertain prostate cancer "H(PCA3,PCT14,PCA18,SCHLAP1,miR-21,PSA,MARAT-1),L(MIR-34a,miR-1,PD-1,PD-L1,SFRP1)" review 30962694 Research status and progress of the RNA or protein biomarkers for prostate cancer 5 mRNA diagnostic biomarker "FAP,BOD1L,RAD51,GSDMD,LGR5,CERS4" human uncertain esophageal cancer esophageal squamous cell cancer "H(FPA),L(LGR 5)" original research 30957200 Whole Exome Sequencing Reveals a Novel Damaging Mutation in Human Fibroblast Activation Protein in a Family with Esophageal Squamous Cell Carcinoma. 6 mRNA diagnostic biomarker TP53 human uncertain leukaemia H original research 30955249 Strong expression of p53 protein in bone marrow samples after hematopoietic stem cell transplantation indicates risk of relapse in pediatric acute lymphoblastic leukemia patients. 7 mRNA diagnostic biomarker LAPTM4B human tissue lung cancer non-small cell lung cancer H original research 30940109 LAPTM4B is a novel diagnostic and prognostic marker for lung adenocarcinoma and associated with mutant EGFR. 8 mRNA diagnostic biomarker "DNALI1,RSPH4A,RSPH9,DNAI2,ALDH3A1" human serum nasopharyngeal cancer L(DNAI1) original research 30935420 Bioinformatic identification of candidate biomarkers and related transcription factors in nasopharyngeal carcinoma. 9 mRNA diagnostic biomarker PIWIL2 human uncertain thymic cancer "H(PLK5,HMGA2,REG4),L(SFRP,CXCL,CAV)" original research 30932350 Can the expression level of PIWIL 2 gene be a serum marker for prostate cancer? A single-center prospective study. 10 mRNA diagnostic biomarker "SMYD2,SMYD3" human tissue breast cancer "H(SMYD2),L(SMYD1/4)" original research 30930987 Expression patterns and the prognostic value of the SMYD family members in human breast carcinoma using integrative bioinformatics analysis. 11 mRNA diagnostic biomarker "SMYD2,SMYD3" human tissue breast cancer triple-negative breast cancer uncertain original research 30930932 Identification of Triple-Negative Breast Cancer Genes and a Novel High-Risk Breast Cancer Prediction Model Development Based on PPI Data and Support Vector Machines. 12 mRNA diagnostic biomarker "NANOG,ALDH1" human tissue lung cancer non-small cell lung cancer H original research 30923946 ALDH1 expression correlates with an epithelial-like phenotype and favorable prognosis in lung adenocarcinoma: a study based on immunohistochemistry and mRNA expression data. 13 mRNA diagnostic biomarker ELAVL2 human uncertain lung cancer non-small cell lung cancer "H(CXCL12,Cdh1,CASP3,CREB1,COL1A1,ERBB 2,ENO 2)" original research 30920015 DNA methylation-based diagnostic and prognostic biomarkers of nonsmoking lung adenocarcinoma patients. 14 mRNA diagnostic biomarker TUG1 human "serum,cell" prostate cancer "H(CXCL12,Cdh1,CASP3,CREB 1,COL1D1,ERBB1,ER1)" original research 30915735 TUG1 promotes the development of prostate cancer by regulating RLIM. 15 mRNA diagnostic biomarker NDRG1 human tissue bladder cancer H original research 30914736 Upregulation of NDRG1 predicts poor outcome and facilitates disease progression by influencing the EMT process in bladder cancer. 16 mRNA diagnostic biomarker EGFR human uncertain lung cancer non-small cell lung cancer uncertain original research 30912007 Association of EGFR 1 Gene Alteration and their Association with Lung Adenocarcinoma Patients 17 mRNA diagnostic biomarker CEP55 human tissue renal cancer clear cell renal cell cancer uncertain original research 30896867 Diagnostic and prognostic value of CEP55 in clear cell renal cell carcinoma as determined by bioinformatics analysis. 18 mRNA diagnostic biomarker GATA1 human blood myeloma BCR-ABL negative myeloproliferative neoplasm L original research 30889303 GATA-1 a potential novel biomarker for the differentiation of essential thrombocythaemia and myelofibrosis. 19 mRNA diagnostic biomarker "TOP2A,TTK,CHEK1,CENPA" human uncertain adrenocortical cancer H original research 30886771 Identification of four hub genes associated with adrenocortical carcinoma progression by WGCNA. 20 mRNA diagnostic biomarker FISH human uncertain mesothelioma pleural mesothelioma H(p16) original research 30885529 The importance of FISH signal cut-off values for 9p21 deletion in malignant pleural mesothelioma: Is it underestimated? 21 mRNA diagnostic biomarker "CEP78,WDR62" human tissue thyroid cancer L(CEP78) original research 30884127 Significance of CEP78 and WDR62 gene expressions in differentiated thyroid carcinoma: Possible predictors of lateral lymph node metastasis. 22 mRNA diagnostic biomarker "AKT1,PRDM10,FAS,FLNA" human uncertain prostate cancer H original research 30872976 Identification of aberrantly methylated differentially expressed genes in prostate carcinoma using integrated bioinformatics. 23 mRNA diagnostic biomarker PTPN2 human tissue breast cancer H(HER2) original research 30867772 ERBB2 and PTPN2 gene copy numbers as prognostic factors in HER2-positive metastatic breast cancer treated with trastuzumab. 24 mRNA diagnostic biomarker SPP1 human "tissue,plasma" urothelial cancer upper urothelial cancer H original research 30844659 Identification of plasma secreted phosphoprotein 1 as a novel biomarker for upper tract urothelial carcinomas. 25 mRNA diagnostic biomarker "TOR,MET,VEGFA,FGF19,HLA" human uncertain hepatocellular cancer H(MET) review 30838478 "Biomarkers: What Role Do They Play (If Any) for Diagnosis, Prognosis and Tumor Response Prediction for Hepatocellular Carcinoma?" 26 mRNA diagnostic biomarker KIF11 human tissue renal cancer clear cell renal cell cancer H original research 30819726 High kinesin family member 11 expression predicts poor prognosis in patients with clear cell renal cell carcinoma. 27 mRNA diagnostic biomarker "FEZ2,PTPRE,ATP2A2,CBLB,MRNIP,CPE,FSTL1,ZNF396,FRAS1,NAV2,LCA5" human tissue thymic cancer L original research 30816514 Genome‑wide DNA methylation profile of thymomas and potential epigenetic regulation of thymoma subtypes. 28 mRNA diagnostic biomarker HLF human serum hepatocellular cancer H(variant-type hepcidin mrna) original research 30798808 Splicing variant of hepcidin mRNA. 29 mRNA diagnostic biomarker ZFP57 human cell breast cancer L original research 30787268 ZFP57 suppress proliferation of breast cancer cells through down-regulation of MEST-mediated Wnt/β-catenin signalling pathway. 30 mRNA diagnostic biomarker HOXA1 human "serum,cell" breast cancer H original research 30783466 HOXA1 upregulation is associated with poor prognosis and tumor progression in breast cancer. 31 mRNA diagnostic biomarker "ACTA2,CDC20,MYH11,TGFB3,TPM1,VIM,DCN" human uncertain bladder cancer H original research 30779109 The identification of new biomarkers for bladder cancer: A study based on TCGA and GEO datasets. 32 mRNA diagnostic biomarker "MMP7,FOS,A2M" human uncertain pancreatic cancer uncertain original research 30767554 Pancreatic cancer biomarker detection by two support vector strategies for recursive feature elimination. 33 mRNA diagnostic biomarker POU5F1B human tissue cervical cancer uncertain original research 30762028 "The Octamer-Binding Transcription Factor 4 (OCT4) Pseudogene, POU Domain Class 5 Transcription Factor 1B (POU5F1B), is Upregulated in Cervical Cancer and Down-Regulation Inhibits Cell Proliferation and Migration and Induces Apoptosis in Cervical Cancer Cell Lines." 34 mRNA diagnostic biomarker HRG human uncertain colorectal cancer H original research 30755640 Prognostic nomogram of hypoxia-related genes predicting overall survival of colorectal cancer-Analysis of TCGA database. 35 mRNA diagnostic biomarker RET human uncertain thyroid cancer H review 30736185 Multiple endocrine neoplasia type 2. 36 mRNA diagnostic biomarker HMLH1 human tissue leukemia H(RUNX3) original research 30719500 Expression and Prognosis Analyses of Runt-Related Transcription Factor Family in Human Leukemia. 37 mRNA diagnostic biomarker "CDC20,AURKB,BIRC5,RRM2,MCM2,PTTG1,CDKN2A,NEK2,CENPF,RACGAP1,GNA14,CDCA5" human tissue hepatocellular cancer "H(CDCA5,CDC20,AURKB,RRM2,PTTG1,CDKN2A,NEK2,GNA14)" original research 30719129 Aberrantly DNA Methylated-Differentially Expressed Genes and Pathways in Hepatocellular Carcinoma. 38 mRNA diagnostic biomarker "TP53,CD44" human uncertain colorectal cancer H original research 30717315 "Potential Applications of DNA, RNA and Protein Biomarkers in Diagnosis, Therapy and Prognosis for Colorectal Cancer: A Study from Databases to AI-Assisted Verification." 39 mRNA diagnostic biomarker DMGs human uncertain epithelial cancer uncertain original research 30706927 Comprehensive bioinformation analysis of methylated and differentially expressed genes in esophageal squamous cell carcinoma. 40 mRNA diagnostic biomarker "LAMC2,ANXA2,ADAM9,APLP2" human uncertain pancreatic cancer H original research 30700038 An Integrative Data Mining and Omics-Based Translational Model for the Identification and Validation of Oncogenic Biomarkers of Pancreatic Cancer. 41 mRNA diagnostic biomarker SLC50A1 human "tissue,serum" breast cancer H original research 30697078 The novel sugar transporter SLC50A1 as a potential serum-based diagnostic and prognostic biomarker for breast cancer. 42 mRNA diagnostic biomarker FAM64A human tissue pancreatic cancer H original research 30695070 Aberrant FAM64A mRNA expression is an independent predictor of poor survival in pancreatic cancer. 43 mRNA diagnostic biomarker IGF2 rat "tissue,serum" hepatocellular cancer H original research 30692043 Alteration of oncogenic IGF-II gene methylation status associates with hepatocyte malignant transformation. 44 mRNA diagnostic biomarker "COL3A1,FN1,COL5A1,FBN1,COL6A1,THBS2" human tissue bladder cancer H original research 30689556 Identification of biomarkers associated with progression and prognosis in bladder cancer via co-expression analysis. 45 mRNA diagnostic biomarker "MCAM,VEGFA" human tissue ovarian cancer epithelial ovarian cancer H original research 30675307 Clinical significance of melanoma cell adhesion molecule CD146 and VEGFA expression in epithelial ovarian cancer. 46 mRNA diagnostic biomarker TGFBI human uncertain colorectal cancer H original research 30672027 Epigenetic profiling and mRNA expression reveal candidate genes as biomarkers for colorectal cancer. 47 mRNA diagnostic biomarker "EGF,CDK1,ENDRA,NGFR,OIP5,NUF2,CDCA8" human uncertain Wilms' tumor H original research 30664180 Weighted gene co‑expression network analysis for identifying hub genes in association with prognosis in Wilms tumor. 48 mRNA diagnostic biomarker LACTB human tissue hepatocellular cancer uncertain original research 30662658 Low expression of LACTB promotes tumor progression and predicts poor prognosis in hepatocellular carcinoma. 49 mRNA diagnostic biomarker ZYX human uncertain uncertain uncertain review 30657586 Zyxin:amechanotransductortoregulategeneexpression. 50 mRNA diagnostic biomarker "CCL19,CXCL1,CXCL5,CXCL11,CXCL12,GNG4,INSL5,NMU,PYY,SST" human uncertain colorectal cancer "H(CXCL1,CXCL5,NMU)" original research 30654001 Identification of biomarkers associated with diagnosis and prognosis of colorectal cancer patients based on integrated bioinformatics analysis. 51 mRNA diagnostic biomarker GDF15 human tissue gastric cancer H original research 30652072 "Utility of GDF-15 as a diagnostic biomarker in gastric cancer: an investigation combining GEO, TCGA and meta-analysis." 52 mRNA diagnostic biomarker COL1A1 human tissue colorectal cancer H original research 30643458 Identification of hub genes and outcome in colon cancer based on bioinformatics analysis. 53 mRNA diagnostic biomarker HEG1 human tissue mesothelioma pleural mesothelioma H(EZH2) review 30642555 Molecular pathways and diagnosis in malignant mesothelioma: A review of the 14th International Conference of the International Mesothelioma Interest Group. 54 mRNA diagnostic biomarker "TMPRSS4,SERPINB5,SLC6A14,SCEL,TNS4" human tissue pancreatic cancer "H(TMC7,TMPRSS4,SCEL,SLC2A1,CENPF,SERPINB5,SLC6A14)" original research 30639415 Identification of candidate diagnostic and prognostic biomarkers for pancreatic carcinoma. 55 mRNA diagnostic biomarker PI15 human "tissue,plasma" "hepatobiliary cancer,cholangio cancer" H original research 30638862 Peptidase inhibitor 15 as a novel blood diagnostic marker for cholangiocarcinoma. 56 mRNA diagnostic biomarker PSAT1 human tissue ovarian cancer H original research 30633343 Identification of molecular marker associated with ovarian cancer prognosis using bioinformatics analysis and experiments. 57 mRNA diagnostic biomarker "CALD1,CNN1,TAGLN" human tissue bladder cancer L original research 30633156 "CALD1, CNN1, and TAGLN identified as potential prognostic molecular markers of bladder cancer by bioinformatics analysis." 58 mRNA diagnostic biomarker "SOX10,GATA3,GCDFP15" human uncertain "breast cancer,lung cancer" "triple-negative breast cancer,TTF1-negative lung adenocarcinoma" H(SOX10) original research 30628926 "SOX10, GATA3, GCDFP15, Androgen Receptor, and Mammaglobin for the Differential Diagnosis Between Triple-negative Breast Cancer and TTF1-negative Lung Adenocarcinoma." 59 mRNA diagnostic biomarker "FTH,FTL" human urine prostate cancer H original research 30610587 "Screening, identification of prostate cancer urinary biomarkers and verification of important spots." 60 mRNA diagnostic biomarker "SNAIL,TWIST1,ZEB" human uncertain mesothelioma H original research 30609805 Epithelial to Mesenchymal Transition in Human Mesothelial Cells Exposed to Asbestos Fibers: Role of TGF-β as Mediator of Malignant Mesothelioma Development or Metastasis via EMT Event. 61 mRNA diagnostic biomarker "SERPINA1,ENOSF1,IGFBP4" human plasma ovarian cancer H original research 30598658 The plasma peptides of ovarian cancer. 62 mRNA diagnostic biomarker HHIP human tissue gastric cancer L original research 30588248 Hedgehog Interacting Protein 1 is a Prognostic Marker and Suppresses Cell Metastasis in Gastric Cancer. 63 mRNA diagnostic biomarker "combine(HER2,MKI67,GSTP1)" human tissue breast cancer L(GSTP1) original research 30585764 "Combined Detection of HER2, Ki67, and GSTP1 Genes on the Diagnosis and Prognosis of Breast Cancer." 64 mRNA diagnostic biomarker PCA3 human urine prostate cancer H original research 30583827 Correlation of mRNA-PCA3 urine levels with the new grading system in prostate cancer. 65 mRNA diagnostic biomarker "COL5A1,COL1A1,COL10A1,COL11A1,CCL20,CXCL5" human uncertain thyroid cancer thyroid papillary cancer uncertain original research 30572540 Prediction of novel target genes and pathways involved in tall cell variant papillary thyroid carcinoma. 66 mRNA diagnostic biomarker ZNF516 human tissue cervical cancer L original research 30564931 Loss of ZNF516 protein expression is related with HR-HPV infection and cervical preneoplastic lesions. 67 mRNA diagnostic biomarker "combine(CEA,EPCAM,KRT19,MUC1,EGFR,MET)" human tissue colorectal cancer H original research 30556647 Six-gene Assay as a new biomarker in the blood of patients with colorectal cancer: establishment and clinical validation. 68 mRNA diagnostic biomarker "SCOC,SYPL1,THAP1" human tissue thyroid cancer thyroid papillary cancer uncertain original research 30539831 Identification of differentiated functional modules in papillary thyroid carcinoma by analyzing differential networks. 69 mRNA diagnostic biomarker "SPINK1,TXNRD1,LCAT,PZP" human tissue hepatocellular cancer H(TXNRD1) original research 30538557 Large-scale analysis reveals a novel risk score to predict overall survival in hepatocellular carcinoma. 70 mRNA diagnostic biomarker FZD2 human tissue oral cancer oral squamous cell cancer "H(LAMC2,SHC1,SIAH1)" original research 30536474 Pathway based prognostic gene expression profile of buccal and gingivo-buccal oral squamous cell carcinoma in smokeless tobacco chewers. 71 mRNA diagnostic biomarker "KRT19,CEACAM5" human uncertain breast cancer H original research 30535933 KRT19 and CEACAM5 mRNA-marked circulated tumor cells indicate unfavorable prognosis of breast cancer patients. 72 mRNA diagnostic biomarker POMC human uncertain pituitary tumor secreting pituitary adenoma H original research 30532734 Integration of Proteomics and Metabolomics Revealed Metabolite-Protein Networks in ACTH-Secreting Pituitary Adenoma. 73 mRNA diagnostic biomarker ENO1 human tissue hepatocellular cancer H original research 30532594 Enolase-1 serves as a biomarker of diagnosis and prognosis in hepatocellular carcinoma patients. 74 mRNA diagnostic biomarker "TOP2A,NDC80,CEP55,CDKN3,CDK1" human tissue adrenocortical cancer H original research 30519354 Identification of Five Genes as a Potential Biomarker for Predicting Progress and Prognosis in Adrenocortical Carcinoma. 75 mRNA diagnostic biomarker DLG1 human uncertain uncertain "cervical cancer,colon adenocarcinoma" H(HTLV-1) review 30517074 Differential expression of DLG1 as a common trait in different human diseases: an encouraging issue in molecular pathology. 76 mRNA diagnostic biomarker "SETD2,EGFR" human tissue soft tissue tumor L original research 30513863 Low HIF-1α and low EGFR mRNA Expression Significantly Associate with Poor Survival in Soft Tissue Sarcoma Patients; the Proteins React Differently. 77 mRNA diagnostic biomarker "NPY1R,PPYR1,PTGDR,PTGER2,PTGER3,SSTR2" human uncertain gastric cancer H original research 30510283 Whole genome MBD-seq and RRBS analyses reveal that hypermethylation of gastrointestinal hormone receptors is associated with gastric carcinogenesis. 78 mRNA diagnostic biomarker AWT1 human tissue leukaemia H original research 30506133 The clinical significance of the alternative Wilms tumor gene overexpression-hypermethylation signature in acute myeloid leukemia. 79 mRNA diagnostic biomarker CFL1 human tissue colorectal cancer H original research 30505577 Study of cofilin 1 gene expression in colorectal cancer. 80 mRNA diagnostic biomarker HIPK3 human tissue lung cancer non-small cell lung cancer L original research 30498360 The expression level and prognostic value of HIPK3 among non-small-cell lung cancer patients in China. 81 mRNA diagnostic biomarker PCA3 human uncertain hematological tumor H review 30466456 Long non-coding RNAs in hematological malignancies: translating basic techniques into diagnostic and therapeutic strategies. 82 mRNA diagnostic biomarker "LEF1,CD200" human tissue leukaemia H original research 30458196 Cortactin expression in non-Hodgkin B-cell lymphomas: a new marker for the differential diagnosis between chronic lymphocytic leukemia and mantle cell lymphoma. 83 mRNA diagnostic biomarker "CDK1,TOP2A,UBE2C" human uncertain ovarian cancer epithelial ovarian cancer "H(CDC20,CDK1,CCNB2 )" original research 30453999 Identification of core genes in ovarian cancer by an integrative meta-analysis. 84 mRNA diagnostic biomarker CDC6 human tissue prostate cancer H original research 30450027 CDC6 mRNA Expression Is Associated with the Aggressiveness of Prostate Cancer. 85 mRNA diagnostic biomarker ZNF185 human tissue epithelial cancer H original research 30446632 ZNF185 is a p53 target gene following DNA damage. 86 mRNA diagnostic biomarker "MMP7,ITGA2" human tissue pancreatic cancer H(ITGA2) original research 30428899 Identification of hub genes with diagnostic values in pancreatic cancer by bioinformatics analyses and supervised learning methods. 87 mRNA diagnostic biomarker MMRD human tissue breast cancer uncertain review 30416850 Mismatch repair-based stratification for immune checkpoint blockade therapy. 88 mRNA diagnostic biomarker FEZF1 human uncertain cervical cancer H original research 30410597 FEZF1 is an Independent Predictive Factor for Recurrence and Promotes Cell Proliferation and Migration in Cervical Cancer. 89 mRNA diagnostic biomarker "RPS21,BIRC5,POLR2H,RPL22L1,NPM1,FOXO1" human uncertain prostate cancer H original research 30405806 Identification of the key genes and pathways in prostate cancer. 90 mRNA diagnostic biomarker CDKN2A dog tissue breast cancer H original research 30396955 Expression Pattern of Cdkn2b and Its Regulators in Canine Mammary Tumors. 91 mRNA diagnostic biomarker "TOP2A,CCNB1,CCNA2,UBE2C,KIF20A,IL6" human uncertain lung cancer non-small cell lung cancer H original research 30369945 Identification of Candidate Biomarkers Correlated With the Pathogenesis and Prognosis of Non-small Cell Lung Cancer via Integrated Bioinformatics Analysis. 92 mRNA diagnostic biomarker MAPRE1 human tissue breast cancer "H(MAPRE1),L(MTUS1)" original research 30368744 Combinatorial expression of microtubule-associated EB1 and ATIP3 biomarkers improves breast cancer prognosis. 93 mRNA diagnostic biomarker "TCF4,CD4,CD56,CD123,TCL1" human plasma cell cancer blastic plasmacytoid dendritic cell neoplasm H(CD123) original research 30350260 Blastic Plasmacytoid Dendritic Cell Neoplasm. 94 mRNA diagnostic biomarker "UBE2C,DLGAP5,TPX2,CCNB2,BIRC5,KIF20A,TOP2A,GNG11,ANXA1" human uncertain lung cancer non-small cell lung cancer "H(UBE2C,DLGAP5,TPX2,CCNB2,BIRC5,KIF20A,TOP2A),L(GNG11,ANXA1)" original research 30349363 Identification of genes and analysis of prognostic values in nonsmoking females with non-small cell lung carcinoma by bioinformatics analyses. 95 mRNA diagnostic biomarker "ERBB2,ESR1,PGR,MMKI67" human tissue breast cancer "(Intraluminal A-like, lumen B-like (HER2 positive), lumen B (like HER2 negative), HER2 positive (non-cavity),triple-negative breast cancer" H original research 30342538 "Robustness of biomarker determination in breast cancer by RT-qPCR: impact of tumor cell content, DCIS and non-neoplastic breast tissue." 96 mRNA diagnostic biomarker TRIB1 human tissue prostate cancer H original research 30337939 "Association Analysis of a Microsatellite Repeat in the TRIB1 Gene With Prostate Cancer Risk, Aggressiveness and Survival." 97 mRNA diagnostic biomarker "NMNAT2,SIRT6" human tissue colorectal cancer "H(NMNAT2),L(SIRT6)" original research 30333863 "Downregulated SIRT6 and upregulated NMNAT2 are associated with the presence, depth and stage of colorectal cancer." 98 mRNA diagnostic biomarker RAPGEF1 human uncertain hepatocellular cancer H(C3GmRNA) review 30302196 How Rap and its GEFs control liver physiology and cancer development. C3G alterations in human hepatocarcinoma. 99 mRNA diagnostic biomarker EGR human uncertain prostate cancer H original research 30301696 A Prospective Study of the Association between Physical Activity and Risk of Prostate Cancer Defined by Clinical Features and TMPRSS2:ERG. 100 mRNA diagnostic biomarker METTL3 human uncertain uncertain H(m6A) review 30296493 It's complicated… m6A-dependent regulation of gene expression in cancer. 101 mRNA diagnostic biomarker LAMP3 human uncertain cervical cancer "H(LAMP3,STAT1,TAP1)" original research 30294508 Transkingdom network reveals bacterial players associated with cervical cancer gene expression program. 102 mRNA diagnostic biomarker RUNX1 human uncertain leukaemia "H(PRKACG,ANKRD7,RNFL7,ROPN11,TEX14,PRMT8,OTOA,CFAP99,NRXN1,DMRT1)" original research 30289875 Identification of Key Genes and Pathways Associated with RUNX1 Mutations in Acute Myeloid Leukemia Using Bioinformatics Analysis. 103 mRNA diagnostic biomarker CDKN2A human cell "laryngeal cancer, cervical cancer" H(p16) original research 30275203 Comparative p16IKN4A Expression in Laryngeal Carcinoma and Cervical Cancer Precursors: A Real-time Grid-based Immunocytochemistry Analysis. 104 mRNA diagnostic biomarker ANXA3 human tissue lung cancer uncertain original research 30274024 "Genome-Wide Analysis of mRNA Expression Profiling Identified Lung Cancer-Related Gene in Xuanwei, China." 105 mRNA diagnostic biomarker CDX2 human tissue colorectal cancer L original research 30257705 CDX2 in colorectal cancer is an independent prognostic factor and regulated by promoter methylation and histone deacetylation in tumors of the serrated pathway. 106 mRNA diagnostic biomarker "IL6,CXCL8" human serum esophageal cancer esophageal squamous cell cancer H original research 30254470 Combined detection of IL-6 and IL-8 is beneficial to the diagnosis of early stage esophageal squamous cell cancer: a preliminary study based on the screening of serum markers using protein chips. 107 mRNA diagnostic biomarker "MAD2L1,CDC20,CCNB1,CCND1,AR,ESR1" human uncertain hepatocellular cancer "H(MAD2L1,CDC20,CCNB1),L(CCND1,AR,ESR1)" original research 30245591 DNA methylation biomarkers for hepatocellular carcinoma. 108 mRNA diagnostic biomarker ANO1 human tissue ovarian cancer H original research 30243029 Inhibition of Ca2+ -activated chloride channel ANO1 suppresses ovarian cancer through inactivating PI3K/Akt signaling. 109 mRNA diagnostic biomarker IL17A human tissue colorectal cancer H original research 30233234 IL-17 and colorectal cancer risk in the Middle East: gene polymorphisms and expression. 110 mRNA diagnostic biomarker MMRN1 human "tissue,serum,cell" lung cancer "H(COL10A1,SPARC)" original research 30227835 Diagnostic role of circulating extracellular matrix-related proteins in non-small cell lung cancer. 111 mRNA diagnostic biomarker DPY30 human tissue ovarian cancer epithelial ovarian cancer H original research 30221689 "DPY30 is required for the enhanced proliferation, motility and epithelial-mesenchymal transition of epithelial ovarian cancer cells." 112 mRNA diagnostic biomarker "PYGL,MEF2C,TRIM36,BUB1,SYNGAP1" human uncertain Ewing sarcoma "H(BUB1B,RACGAP1),L(PYGM,MEF2C,TRIM63)" original research 30221671 Comprehensive analysis of multi Ewing sarcoma microarray datasets identifies several prognosis biomarkers. 113 mRNA diagnostic biomarker "ITGA3,ITGA5,ITGB1,ITGB6" human tissue oral cancer oral squamous cell cancer "H(ITGA3,ITGA5,ITGB1,ITGB6)" original research 30214610 "Evaluation of the mRNA expression levels of integrins α3, α5, β1 and β6 as tumor biomarkers of oral squamous cell carcinoma." 114 mRNA diagnostic biomarker PCDH10 human tissue breast cancer L original research 30214581 Aberrant promoter methylation of PCDH10 as a potential diagnostic and prognostic biomarker for patients with breast cancer. 115 mRNA diagnostic biomarker "KRT7,CK14,EMA,TP63,MKI67" human uncertain adenoid cystic cancer lacrimal gland adenocarcinoma H original research 30212949 Primary poorly differentiated lacrimal gland adenocarcinoma in left ocular region: A rare case report. 116 mRNA diagnostic biomarker "APP,APPBP2,ATXN1,HSP90B1,IKZF1,KRTAP10-1,PAK1,PDPK1,SMAD4,SUZ12,TTP53" human uncertain osteosarcoma "H(APP,HSP90B1,SUZ12,IKZF1) " original research 30210606 Analyzing the disease module associated with osteosarcoma via a network- and pathway-based approach. 117 mRNA diagnostic biomarker "PGAP3,GRB7,MIR4728,PNMT,STARD3,TCAP,ERBB2" human uncertain breast cancer H(ERBB2) original research 30203254 Identification of the copy number variant biomarkers for breast cancer subtypes. 118 mRNA diagnostic biomarker VX2 rabbit uncertain head and neck cancer head and neck squamous cell cancer "H(Egfr,Erbb1)" original research 30194151 The Auricular VX2 Carcinoma Is a Suitable Animal Model for Identifying Biomarkers for HNSCC Therapy Response. 119 mRNA diagnostic biomarker NGEP human serum prostate cancer H original research 30191737 Autoantibody against new gene expressed in prostate protein is traceable in prostate cancer patients. 120 mRNA diagnostic biomarker "BCOR,SATB2" human tissue soft tissue tumor H review 30187985 New advances in the molecular classification of pediatric mesenchymal tumors. 121 mRNA diagnostic biomarker VIM human uncertain hepatocellular cancer "H(SPARC,VIM)" original research 30186410 Identification of key pathways and biomarkers in sorafenib-resistant hepatocellular carcinoma using bioinformatics analysis. 122 mRNA diagnostic biomarker TNIP1 human uncertain breast cancer uncertain original research 30181081 In silico analysis of nsSNPs in ABCB1 gene affecting breast cancer associated protein P-glycoprotein (P-gp). 123 mRNA diagnostic biomarker MMP11 human "tissue,cell" thyroid cancer papillary thyroid carcinoma H original research 30171715 MMP-11 promotes papillary thyroid cell proliferation and invasion via the NF-κB pathway. 124 mRNA diagnostic biomarker HMGB3 rat tissue hepatocellular cancer H original research 30166860 Abnormal expression of HMGB-3 is significantly associated with malignant transformation of hepatocytes. 125 mRNA diagnostic biomarker "combine(FOXM1,CENPF)" human uncertain adrenocortical cancer H original research 30158955 Co-expression Network Analysis of Biomarkers for Adrenocortical Carcinoma. 126 mRNA diagnostic biomarker TNFAIP2 human uncertain cervical cancer H review 30145807 The roles of TNFAIP2 in cancers and infectious diseases. 127 mRNA diagnostic biomarker DSN1 human tissue hepatocellular cancer H original research 30136646 Elevated DSN1 expression is associated with poor survival in patients with hepatocellular carcinoma. 128 mRNA diagnostic biomarker EZH2 human tissue myogenic cancer H original research 30120321 High expression of EZH2 as a marker for the differential diagnosis of malignant and benign myogenic tumors. 129 mRNA diagnostic biomarker HSPE1 human tissue bladder cancer "H(ANXA3,HSPE1)" original research 30112103 Systematic verification of bladder cancer-associated tissue protein biomarker candidates in clinical urine specimens. 130 mRNA diagnostic biomarker "BRAF,DUSP6" human uncertain metanephric adenoma H original research 30111351 Novel clinicopathological and molecular characterization of metanephric adenoma: a study of 28 cases. 131 mRNA diagnostic biomarker "PPARGC1A,CREBBP,EP300,CD44,SPP1,MMP9" human uncertain thyroid cancer H original research 30069928 Identification of candidate aberrantly methylated and differentially expressed genes in thyroid cancer. 132 mRNA diagnostic biomarker ADAR1 human uncertain myeloma multiple myeloma H original research 30061158 Aberrant hyperediting of the myeloma transcriptome by ADAR1 confers oncogenicity and is a marker of poor prognosis. 133 mRNA diagnostic biomarker SPDYE18 mice tissue lung cancer non-small cell lung cancer H original research 30050775 The 180 splice variant of NCAM-containing exon 18-is specifically expressed in small cell lung cancer cells. 134 mRNA diagnostic biomarker CHD9 human tissue colorectal cancer L original research 30043858 Decreased expression of chromodomain helicase DNA-binding protein 9 is a novel independent prognostic biomarker for colorectal cancer. 135 mRNA diagnostic biomarker ADAM10 human "tissue,cell" lung cancer non-small cell lung cancer H original research 30026855 ADAM10 Sheddase Activity is a Potential Lung-Cancer Biomarker. 136 mRNA diagnostic biomarker MCM2 human tissue hepatocellular cancer H original research 30026832 Distinct Diagnostic and Prognostic Values of Minichromosome Maintenance Gene Expression in Patients with Hepatocellular Carcinoma. 137 mRNA diagnostic biomarker S100 human tissue breast cancer H original research 30018736 A multiomics analysis of S100 protein family in breast cancer. 138 mRNA diagnostic biomarker ANLN "human,chimpanzee,mouse,zebrafish,,chicken,dog,sheep,cattle,rhesus monkey,rat,pig" uncertain lung cancer non-small cell lung cancer H original research 30008873 Prognostic significance of ANLN in lung adenocarcinoma. 139 mRNA diagnostic biomarker FBP1 human tissue ovarian cancer H original research 30008853 FBP1 promotes ovarian cancer development through the acceleration of cell cycle transition and metastasis. 140 mRNA diagnostic biomarker NETO2 human uncertain renal cancer renal clear cell cancer "H(SAP30,NETO2)" original research 29989576 TranscriptionFactorSAP30IsInvolvedintheActivationofNETO2GeneExpressioninClearCellRenalCellCarcinoma. 141 mRNA diagnostic biomarker RAGE human tissue uncertain Multiple cancers "H(RAGE,AGEs,S100)" review 29987748 "RAGE and Its Ligands: Molecular Interplay Between Glycation, Inflammation, and Hallmarks of Cancer-a Review." 142 mRNA diagnostic biomarker "MACC1,MYC" human "tissue,serum" uterine cancer endometrial cancer H original research 29984790 Correlation of MACC1/c-Myc Expression in Endometrial Carcinoma with Clinical/Pathological Features or Prognosis. 143 mRNA diagnostic biomarker "TOP2A,CCNB1,KIF4A" human uncertain hepatocellular cancer H original research 29977454 The Identification of Core Gene Expression Signature in Hepatocellular Carcinoma. 144 mRNA diagnostic biomarker PCA3 human uncertain prostate cancer H original research 29970667 Urine PCA3 mRNA level in diagnostic of prostate cancer. 145 mRNA diagnostic biomarker ZNF154 human tissue prostate cancer L original research 29966681 ZNF154 is a promising diagnosis biomarker and predicts biochemical recurrence in prostate cancer. 146 mRNA diagnostic biomarker "PTGS2,PIK3CD,CXCL1,ESR1,MMP2,CDC45,DTL,AURKB,CDKN3,MCM2,MCM10" human uncertain hepatocellular cancer "H(CDC45,DTL,AURKB,CDKN3,MCM2,MCM10),L(PTGS2,PIK3CD,CXCL1,ESR1,MMP2)" original research 29962817 Bioinformatics analysis of aberrantly methylated-differentially expressed genes and pathways in hepatocellular carcinoma. 147 mRNA diagnostic biomarker TXNIP human tissue ductal cancer breast ductal cancer L original research 29955142 Thioredoxin-interacting protein is an independent risk stratifier for breast ductal carcinoma in situ. 148 mRNA diagnostic biomarker "MME,PHLDA1,KRT20" human uncertain cell cancer "trichoblastoma,basal cell carcinoma" "H(CK20,TDAG51,INSM1,CD10,AR)" original research 29938548 "CD10, TDAG51, CK20, AR, INSM1, and Nestin Expression in the Differential Diagnosis of Trichoblastoma and Basal Cell Carcinoma." 149 mRNA diagnostic biomarker PRMT6 human tissue colorectal cancer L original research 29927001 Significant association of PRMT6 hypomethylation with colorectal cancer. 150 mRNA diagnostic biomarker GOLPH3 human "tissue,serum" hepatocellular cancer H original research 29914442 Golgi phosphoprotein 3 (GOLPH3) promotes hepatocellular carcinoma progression by activating mTOR signaling pathway. 151 mRNA diagnostic biomarker DKC1 human tissue renal cancer clear cell renal cell carcinoma H original research 29901172 "DKC1 serves as a potential prognostic biomarker for human clear cell renal cell carcinoma and promotes its proliferation, migration and invasion via the NF‑κB pathway." 152 mRNA diagnostic biomarker IDO1 human tissue prostate cancer Bioinformatics and functional analyses of key genes and pathways in human clear cell renal cell carcinoma. H original research 29896191 "Expression of Indoleamine 2,3-Dioxygenase Induced by IFN-γ and TNF-α as Potential Biomarker of Prostate Cancer Progression." 153 mRNA diagnostic biomarker LAPTM4B human "tissue,serum" hepatocellular cancer H original research 29882487 Expression signature of lysosomal-associated transmembrane protein 4B in hepatitis C virus-induced hepatocellular carcinoma. 154 mRNA diagnostic biomarker "CCND1,BCL2" human tissue colorectal cancer sporadic colorectal cancer "H(CCND),L(BCL2)" original research 29849793 Expression profile of NF-κB regulated genes in sporadic colorectal cancer patients. 155 mRNA diagnostic biomarker EZH2 human uncertain lung cancer small cell lung cancer "H(CDKN3,TYMS)" original research 29845250 Identification of candidate biomarkers and pathways associated with SCLC by bioinformatics analysis. 156 mRNA diagnostic biomarker "HSPB1,TP53" dog tissue uncertain Multiple cancers uncertain original research 29845068 Expression Profiling of Hspb1 and Tp53 Genes through RT-qPCR in Different Cancer Types of Canis familiaris. 157 mRNA diagnostic biomarker ULMS human uncertain uterine cancer "uterine leiomyosarcoma,uterine serous papillary cancer" "H(CCNE1,FOXM1,MMP9,ESR1),L(AR,WT1)" original research 29844831 Identification of key genes and pathways in uterine leiomyosarcoma through bioinformatics analysis. 158 mRNA diagnostic biomarker "MME,ALB,CDH1,ROM1,CXCL12,ICAM1" human tissue renal cancer clear cell renal cell carcinoma "H(PTPRC,ICAM1),L(MME,ALB,CDH1,ROM1,C-X-C motif,CXCL12)" original research 29805645 Bioinformatics and functional analyses of key genes and pathways in human clear cell renal cell carcinoma. 159 mRNA diagnostic biomarker "JUN,EGR1,MYC,CDKN1A" human uncertain hepatocellular cancer "H(EGR1,MYC,CDKN1A)" original research 29795057 Identification of Biological Targets of Therapeutic Intervention for Hepatocellular Carcinoma by Integrated Bioinformatical Analysis. 160 mRNA diagnostic biomarker "PHB1,PHB2" human tissue uncertain L review 29784973 Significance of prohibitin domain family in tumorigenesis and its implication in cancer diagnosis and treatment. 161 mRNA diagnostic biomarker LAG3 human uncertain uncertain uncertain original research 29772383 A signal-decreased electrochemical immunosensor for the sensitive detection of LAG-3 protein based on a hollow nanobox-MOFs/AuPt alloy. 162 mRNA diagnostic biomarker EGFR human uncertain uncertain glioblastoma multiforme L(MDA-9) review 29760085 MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells. 163 mRNA diagnostic biomarker "CDH1,ERBB" human tissue gastric cancer uncertain original research 29755769 An assessment of candidate genes to assist prognosis in gastric cancer. 164 mRNA diagnostic biomarker ETV6 mice tissue secretory cancer mammary analogue secretory carcinoma uncertain original research 29752049 The screening and electron microscopy observation of mammary analogue secretory carcinoma in Chinese. 165 mRNA diagnostic biomarker "MLH1,MSH2,MSH6,PMS2" human tissue lynch syndrome uncertain review 29744602 Current clinical topics of Lynch syndrome. 166 mRNA diagnostic biomarker "GPX3,DKK3,GSTM1,KIP2" human tissue prostate cancer uncertain original research 29740534 Genomic DNA Methylation-Derived Algorithm Enables Accurate Detection of Malignant Prostate Tissues. 167 mRNA diagnostic biomarker EBI3 human tissue hepatocellular cancer H original research 29740492 Downregulation of Epstein-Barr virus-induced gene 3 is associated with poor prognosis of hepatocellular carcinoma after curative resection. 168 mRNA diagnostic biomarker "GNG4,ADCY9,NPY,ADRA2B,PENK" human uncertain bladder cancer uncertain original research 29739919 Identification of Core Genes and Key Pathways via Integrated Analysis of Gene Expression and DNA Methylation Profiles in Bladder Cancer. 169 mRNA diagnostic biomarker WDR5 human tissue hepatocellular cancer H original research 29731905 Effect of high WDR5 expression on the hepatocellular carcinoma prognosis. 170 mRNA diagnostic biomarker "CDC20,CENPF,KIF2C,BUB1,ZWINT" human tissue lung cancer non-small cell lung cancer H original research 29731852 Identification of potential diagnostic and prognostic biomarkers in non-small cell lung cancer based on microarray data. 171 mRNA diagnostic biomarker HRAS human tissue oral cancer oral squamous cell carcinoma uncertain original research 29731559 Does Harvey-Ras gene expression lead to oral squamous cell carcinoma? A clinicopathological aspect. 172 mRNA diagnostic biomarker "GALNT6,GALNT1" human "tissue,serum" gastric cancer H original research 29729225 Diagnostic utility of glycosyltransferase mRNA expression in gastric cancer. 173 mRNA diagnostic biomarker CGA mice serum uncertain Multiple cancers H original research 29728076 Effective preparation of a monoclonal antibody against human chromogranin A for immunohistochemical diagnosis. 174 mRNA diagnostic biomarker HOXA4 human tissue lung cancer L review 29700285 "HOXA4, down-regulated in lung cancer, inhibits the growth, motility and invasion of lung cancer cells." 175 mRNA diagnostic biomarker TERT human tissue cervical cancer H original research 29668478 Correlation of hTERT Expression with Cervical Cytological Abnormalities and Human Papillomavirus Infection. 176 mRNA diagnostic biomarker MGMT human tissue cervical cancer L original research 29664054 Limited Role of Promoter Methylation of MGMT and C13ORF18 in Triage of Low-Grade Squamous Intraepithelial Lesion. 177 mRNA diagnostic biomarker "GRP,TMEM37" mice tissue colon cancer "H(ULBP2,GRP)" original research 29653552 Independent prognostic genes and mechanism investigation for colon cancer. 178 mRNA diagnostic biomarker "NPBWR1,S1PR3,NPY1R,CXCR3,SSTR1" human uncertain cervical cancer L(MCM5) original research 29642758 Identification of Significant Gene Signatures and Prognostic Biomarkers for Patients With Cervical Cancer by Integrated Bioinformatic Methods. 179 mRNA diagnostic biomarker STAT human tissue glioma "L(STAT-1),H(mutant p53)" original research 29620180 A study on the correlation between STAT‑1 and mutant p53 expression in glioma. 180 mRNA diagnostic biomarker "KRT19,MKI67" human uncertain ductal cancer invasive ductal cancer "L((CK19,Ki-67)" original research 29619374 Modulation of Molecular Biomarker Expression in Response to Chemotherapy in Invasive Ductal Carcinoma. 181 mRNA diagnostic biomarker "CENPA,CDK1,CDC20" human tissue lung cancer non-small cell lung cancer H original research 29608985 "A novel strategy of integrated microarray analysis identifies CENPA, CDK1 and CDC20 as a cluster of diagnostic biomarkers in lung adenocarcinoma." 182 mRNA diagnostic biomarker IFI27 human tissue oral cancer oral squamous cell cancer H original research 29580248 Knockdown of IFI27 inhibits cell proliferation and invasion in oral squamous cell carcinoma. 183 mRNA diagnostic biomarker PCA3 human blood prostate cancer H original research 29574327 Clinical Significance of Peripheral Blood PCA3 Gene Expression in Early Diagnosis of Prostate Cancer. 184 mRNA diagnostic biomarker TP53 mice uncertain uncertain L review 29569948 Targeting p53 as a promising therapeutic option for cancer by re-activating the wt or mutant p53's tumor suppression. 185 mRNA diagnostic biomarker "EGFR,EN1" human uncertain uncertain uncertain original research 29565425 Interfacial nano-mixing in a miniaturised platform enables signal enhancement and in situ detection of cancer biomarkers. 186 mRNA diagnostic biomarker "LCK,GNLY,SLC6A6,LAMP2" human tissue colorectal cancer "H(LCK,GNLY)in stage I,H(SLC6A6,LAMP2)in stage II,L(LCK,GNLY) in stage IV,L(SLC6A6,LAMP2)in stage I" original research 29562499 Potential biomarkers for the early diagnosis of colorectal adenocarcinoma - transcriptomic analysis of four clinical stages. 187 mRNA diagnostic biomarker "HNF4A,TAF1,TTP53" human uncertain gastric cancer "L(HNF4A),H(TP53)" original research 29556568 Gastric cancer biomarkers; A systems biology approach. 188 mRNA diagnostic biomarker ISG15 human "tissue,plasma " esophageal cancer esophageal squamous cell cancer H original research 29555370 ISG15 promotes esophageal squamous cell carcinoma tumorigenesis via c-MET/Fyn/β-catenin signaling pathway. 189 mRNA diagnostic biomarker "WWOX,KRAS,COX2,TP53,APC,DCC,PTEN" human uncertain colorectal cancer H original research 29551923 Establishment of optimal regulatory network of colorectal cancer based on p42.3 protein. 190 mRNA diagnostic biomarker GNA12 human serum hepatocellular cancer "H(GT,CRP,CEA,AFP,CA153,CA199)" original research 29546505 An efficient model for auxiliary diagnosis of hepatocellular carcinoma based on gene expression programming. 191 mRNA diagnostic biomarker RECQL4 human tissue hepatocellular cancer H original research 29541191 Upregulation of RECQL4 expression predicts poor prognosis in hepatocellular carcinoma. 192 mRNA diagnostic biomarker FMR1 human "tissue,plasma" nasopharyngeal cancer uncertain original research 29534591 Low expression of Cyfip1 may be a potential biomarker in nasopharyngeal carcinoma. 193 mRNA diagnostic biomarker "COL11A1,COMP,COL10A1" human "tissue,serum,cell" breast cancer H original research 29521413 Extracellular matrix proteins as diagnostic markers of breast carcinoma. 194 mRNA diagnostic biomarker RNR1 human uncertain colorectal cancer uncertain original research 29511483 Evaluation of involved proteins in colon adenocarcinoma: an interactome analysis. 195 mRNA diagnostic biomarker "TP53,GAPDH,VEGFA,AKT1,ALB,EGFR,MYC,EGF,INS,PIK3CA,JUN,IL6,SRC,HRAS,MAPK1,CCND1,CDH1,TNF,MAPK3,IGF1,PTEN,CTNNB1,NOTCH1,MTOR" human uncertain pancreatic cancer uncertain original research 29511477 Pancreatic adenocarcinoma protein-protein interaction network analysis. 196 mRNA diagnostic biomarker OLFM4 human tissue gastric cancer uncertain original research 29511474 Identification of differentially-expressed of Olfactomedin-related proteins 4 and COL11A1 in Iranian patients with intestinal gastric cancer. 197 mRNA diagnostic biomarker UHRF1 human tissue hepatoblastoma H original research 29507645 Overexpression of UHRF1 promotes silencing of tumor suppressor genes and predicts outcome in hepatoblastoma. 198 mRNA diagnostic biomarker HLA human uncertain uncertain uncertain original research 29505699 Translating Immunopeptidomics to Immunotherapy-Decision-Making for Patient and Personalized Target Selection. 199 mRNA diagnostic biomarker WEE1 human uncertain glioma high-grade glioma H original research 29502292 Whole-Genome Expression Microarray Combined with Machine Learning to Identify Prognostic Biomarkers for High-Grade Glioma. 200 mRNA diagnostic biomarker BIRC5 human uncertain ovarian cancer H original research 29499854 Clinical value of survivin and its underlying mechanism in ovarian cancer: A bioinformatics study based on GEO and TCGA data mining. 201 mRNA diagnostic biomarker "COL7A1,UCN2" human tissue laryngeal cancer H(COL7A1-UCN2) original research 29499655 Identification of novel enriched recurrent chimeric COL7A1-UCN2 in human laryngeal cancer samples using deep sequencing. 202 mRNA diagnostic biomarker PCA3 human tissue prostate cancer L original research 29491074 A Panel of Biomarkers for Diagnosis of Prostate Cancer Using Urine Samples. 203 mRNA diagnostic biomarker CDX2 human tissue colorectal cancer L original research 29467879 Loss of CDX2 gene expression is associated with DNA repair proteins and is a crucial member of the Wnt signaling pathway in liver metastasis of colorectal cancer. 204 mRNA diagnostic biomarker SPINK13 human tissue ovarian cancer L original research 29439245 Downregulation of SPINK13 Promotes Metastasis by Regulating uPA in Ovarian Cancer Cells. 205 mRNA diagnostic biomarker SLC16A13 mice tissue oral cancer oral squamous cell carcinoma H original research 29435078 Gene expression analyses associated with malignant phenotypes of metastatic sub-clones derived from a mouse oral squamous cell carcinoma Sq-1979 cell line. 206 mRNA diagnostic biomarker GTSF1 human "tissue,cell" hepatocellular cancer H original research 29435047 GTSF1 gene may serve as a novel potential diagnostic biomarker for liver cancer. 207 mRNA diagnostic biomarker PLAC1 human serum breast cancer H original research 29432428 PLAC1 as a serum biomarker for breast cancer. 208 mRNA diagnostic biomarker BCL9 human tissue adrenocortical cancer H original research 29428231 BCL9 Upregulation in Adrenocortical Carcinoma: A Novel Wnt/β-Catenin Activating Event Driving Adrenocortical Malignancy. 209 mRNA diagnostic biomarker LITAF human tissue pancreatic cancer L original research 29423035 LITAF is a potential tumor suppressor in pancreatic cancer. 210 mRNA diagnostic biomarker SF3B4 human tissue hepatocellular cancer H original research 29397868 SF3B4 as an early-stage diagnostic marker and driver of hepatocellular carcinoma. 211 mRNA diagnostic biomarker SCD1 human uncertain bladder cancer H original research 29396722 Increased expression of the gene encoding stearoyl-CoA desaturase 1 in human bladder cancer. 212 mRNA diagnostic biomarker "AKR7A3,AKR1B10" rat tissue hepatocellular cancer H original research 29383608 Aldo-Keto Reductases as Early Biomarkers of Hepatocellular Carcinoma: A Comparison Between Animal Models and Human HCC. 213 mRNA diagnostic biomarker "ITGA11,COPS5" human tissue breast cancer uncertain original research 29383106 Analysis of differential gene expression profile identifies novel biomarkers for breast cancer. 214 mRNA diagnostic biomarker "TP53,EGFR,MYC,AKT1,CDKN2A,CCND1,HSP90AA1" human uncertain "colorectal cancer,esophageal cancer,gastric cancer" H original research 29379595 "Network analysis of common genes related to esophageal, gastric, and colon cancers." 215 mRNA diagnostic biomarker "RASGRP2,IKZF1,CXCR5,LTB,BLK,LINGO3,CCR6,P2RY10,RHOH,JUP,KRT14,PLA2G3,SPRR1A,KRT78,SFN,CLDN4,IL1RN,PKP3,CBLC,KRT16,TMEM79,KLK8,LYPD3,LYPD5" human uncertain cutaneous cancer uncertain original research 29377892 Network-based co-expression analysis for exploring the potential diagnostic biomarkers of metastatic melanoma. 216 mRNA diagnostic biomarker PIWIL2 human tissue thyroid cancer papillary thyroid carcinoma H original research 29369786 Differential expression of PIWIL2 in papillary thyroid cancers. 217 mRNA diagnostic biomarker HMGB1 human tissue mesothelioma pleural mesothelioma H original research 29356044 Expression analysis of HMGB1 in histological samples of malignant pleural mesothelioma. 218 mRNA diagnostic biomarker "TP53,MKI67" human uncertain bladder cancer H(Ki-67) original research 29354488 Impact of the Ki-67 labeling index and p53 expression status on disease-free survival in pT1 urothelial carcinoma of the bladder. 219 mRNA diagnostic biomarker "MMP2,MMP7,MMP9" human tissue bladder cancer H original research 29349669 Positive Correlation between Matrix Metalloproteinases and Epithelial-to-Mesenchymal Transition and its Association with Clinical Outcome in Bladder Cancer Patients. 220 mRNA diagnostic biomarker MAPK human tissue gastric cancer uncertain original research 29344174 Expression profile of cytokines in gastric cancer patients using proteomic antibody microarray. 221 mRNA diagnostic biomarker SHISA2 human uncertain prostate cancer H original research 29344118 SHISA2 enhances the aggressive phenotype in prostate cancer through the regulation of WNT5A expression. 222 mRNA diagnostic biomarker "ZNF281,EPHB6" human uncertain cervical cancer "H(ZNF281),L(EPHB6)" original research 29312619 Systematic assessment of cervical cancer initiation and progression uncovers genetic panels for deep learning-based early diagnosis and proposes novel diagnostic and prognostic biomarkers. 223 mRNA diagnostic biomarker SATB1 human uncertain uncertain Multiple cancers H review 29306014 The Special AT-rich Sequence Binding Protein 1 (SATB1) and its role in solid tumors. 224 mRNA diagnostic biomarker TFF1 human tissue esophageal cancer esophageal squamous cell cancer L original research 29296124 TFF1 hypermethylation and decreased expression in esophageal squamous cell carcinoma and histologically normal tumor surrounding esophageal cells. 225 mRNA diagnostic biomarker "TP53,EGFR,AKT1" human uncertain esophageal cancer uncertain original research 29286604 Protein-Protein Interaction Network Analysisfora Biomarker Panel Relatedto Human Esophageal Adeno carcinoma 226 mRNA diagnostic biomarker "JUN,FYN,CAV1,SFN" human tissue lung cancer non-small cell lung cancer "L(JUN,CAV1,FYN),H(SFN)" original research 29266838 Identification of differential protein-coding gene expressions in early phase lung adenocarcinoma. 227 mRNA diagnostic biomarker MMP1 human uncertain squamous cell cancer uncertain original research 29249121 Matrix metalloproteinase 1: a better biomarker for squamous cell carcinoma by multiple microarray analyses. 228 mRNA diagnostic biomarker "combine(AQP1,CTNNB1)" human uncertain glioma H original research 29245912 Combination of AQP1 and β-catenin expression is an independent prognosis factor in astrocytoma patients. 229 mRNA diagnostic biomarker H3F3A human uncertain bone cancer giant cell tumors of bone uncertain original research 29241742 "Diagnostic utility of histone H3.3 G34W, G34R, and G34V mutant-specific antibodies for giant cell tumors of bone." 230 mRNA diagnostic biomarker "RAC1,APP,EGFR,KNG1,AGT,HRAS" human uncertain tongue cancer tongue squamous cell carcinoma "H(RAC1,APP),L(KNG,AGT)" original research 29240723 Identification of Key Genes and Pathways in Tongue Squamous Cell Carcinoma Using Bioinformatics Analysis. 231 mRNA diagnostic biomarker SETBP1 human uncertain myeloma myeloproliferative neoplasm H review 29225884 SETBP1 mutations as a biomarker for myelodysplasia /myeloproliferative neoplasm overlap syndrome. 232 mRNA diagnostic biomarker PAX3 human cell sinus cancer uncertain original research 29224278 Clinicopathologic and molecular genetic characterizations of biphenotypic sinonasal sarcoma. 233 mRNA diagnostic biomarker PTTG1 human tissue adrenocortical cancer H original research 29218429 Protein Expression of PTTG1 as a Diagnostic Biomarker in Adrenocortical Carcinoma. 234 mRNA diagnostic biomarker "E2F1,E2F2,RB1,CCND1,CDH18,LAMA1" human uncertain osteosarcoma L(LAMA1) original research 29207108 Integrated analysis of gene expression and copy number variations in MET proto‑oncogene‑transformed human primary osteoblasts. 235 mRNA diagnostic biomarker BAP1 human tissue mesothelioma L original research 29206890 Validation of the diagnosis of mesothelioma and BAP1 protein expression in a cohort of asbestos textile workers from Northern Italy. 236 mRNA diagnostic biomarker "BPNET,TNETS" human uncertain neuroblastoma H review 29201449 Molecular strategies in the management of bronchopulmonary and thymic neuroendocrine neoplasms. 237 mRNA diagnostic biomarker "SETD2,EPO" human tissue breast cancer invasive breast cancer H(P-gp) original research 29181060 "Expression of multidrug resistance protein P-glycoprotein in correlation with markers of hypoxia (HIF-1α, EPO, EPO-R) in invasive breast cancer with metastasis to lymph nodes." 238 mRNA diagnostic biomarker IGFBP4 human tissue lung cancer H original research 29163706 IGFBP-4 expression is adversely associated with lung cancer prognosis. 239 mRNA diagnostic biomarker "BCL6,CD10,HGAL,LMO2,KLHL6" human tissue lymphoma B-cell lymphoma H original research 29140403 KLHL6 Is Preferentially Expressed in Germinal Center-Derived B-Cell Lymphomas. 240 mRNA diagnostic biomarker PIWIL1 human tissue uncertain "L(piRNAs),H(PIWIL)" review 29130960 PIWI Proteins and PIWI-Interacting RNA: Emerging Roles in Cancer. 241 mRNA diagnostic biomarker MET human uncertain lung cancer non-small cell lung cancer H(c-MET ) original research 29128478 Protein overexpression and gene amplification of cellular mesenchymal-epithelial transition factor is associated with poor prognosis in micropapillary-predominant subtype pulmonary adenocarcinoma. 242 mRNA diagnostic biomarker HOXD10 human tissue thyroid cancer papillary thyroid cancer L original research 29115628 Aberrant hypermethylation of the HOXD10 gene in papillary thyroid cancer with BRAFV600E mutation. 243 mRNA diagnostic biomarker LAPTM4B human "tissue,serum" hepatocellular cancer H original research 29108920 Correlation of lysosome-associated protein transmembrane-4β gene overexpression with the malignant phenotypes of hepatocellular carcinoma. 244 mRNA diagnostic biomarker PNKD human uncertain uncertain H(MR-1) review 29103325 Myofibrillogenesis regulator 1 (MR-1): a potential therapeutic target for cancer and PNKD. 245 mRNA diagnostic biomarker "RUNX3,RASSF1A,RPRM" human blood gastric cancer H original research 29100425 Promoter methylation of tumor-related genes as a potential biomarker using blood samples for gastric cancer detection. 246 mRNA diagnostic biomarker CDC42BPA human cell colorectal cancer H original research 29072916 Comparative Proteomics Analysis Identifies Cdc42-Cdc42BPA Signaling as Prognostic Biomarker and Therapeutic Target for Colon Cancer Invasion. 247 mRNA diagnostic biomarker "AR,CDH13,CDKN2A,DAPK1,CD44,GSTP1,RASSF1" human uncertain prostate cancer L original research 29066912 Identification of key pathways and genes with aberrant methylation in prostate cancer using bioinformatics analysis. 248 mRNA diagnostic biomarker "BANF1,PLOD3,SF3B4" human tissue hepatocellular cancer L original research 29059470 "Barrier to autointegration factor 1, procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3, and splicing factor 3b subunit 4 as early-stage cancer decision markers and drivers of hepatocellular carcinoma." 249 mRNA diagnostic biomarker "MAGEA3,MAGEB4,ODF4" human "tissue,cell" bladder cancer H original research 29058301 Cancer-Testis Antigens as New Candidate Diagnostic Biomarkers for Transitional Cell Carcinoma of Bladder. 250 mRNA diagnostic biomarker CCDC6 human uncertain uncertain H review 29044514 CCDC6: the identity of a protein known to be partner in fusion. 251 mRNA diagnostic biomarker PHF20 human uncertain glioma glioblastoma H original research 29033691 Identification of genes and pathways potentially related to PHF20 by gene expression profile analysis of glioblastoma U87 cell line. 252 mRNA diagnostic biomarker TWIST1 human tissue uncertain H original research 29029429 Twist1 is highly expressed in cancer-associated fibroblasts of esophageal squamous cell carcinoma with a prognostic significance. 253 mRNA diagnostic biomarker "AFP,THBS4,LCN2,GPC3,NUF2,TTK,MELK,BUB1,NEK2,BUB1B,AURKB,PLK1,CDK1,PKMYT1,PBK" human "tissue,cell" hepatocellular cancer H original research 29025594 "Gene expression profiling, pathway analysis and subtype classification reveal molecular heterogeneity in hepatocellular carcinoma and suggest subtype specific therapeutic targets." 254 mRNA diagnostic biomarker ESM1 human cell head and neck cancer H original research 29024069 Functional analysis of ESM1 by siRNA knockdown in primary and metastatic head and neck cancer cells. 255 mRNA diagnostic biomarker "SCARA5,RUNX3" human blood hepatocellular cancer H original research 29019900 "Methylation analysis of p16, SLIT2, SCARA5, and Runx3 genes in hepatocellular carcinoma." 256 mRNA diagnostic biomarker "FOXD1,ELF5,HOXA5,KLF5" human tissue lung cancer non-small cell lung cancer H(FOXD1) original research 28983631 Integrated analysis reveals candidate genes and transcription factors in lung adenocarcinoma. 257 mRNA diagnostic biomarker TWIST1 human cell ductal cancer "L(TWIST,PDPN)" original research 28982860 Correlation Between Expression of Twist and Podoplanin in Ductal Breast Carcinoma. 258 mRNA diagnostic biomarker "KCNN4,KCNMA1" human tissue renal cancer uncertain original research 28975890 Identification and validation of novel prognostic markers in Renal Cell Carcinoma. 259 mRNA diagnostic biomarker PCNA human tissue nasopharyngeal cancer uncertain original research 28969025 Identification of genes and pathways in nasopharyngeal carcinoma by bioinformatics analysis. 260 mRNA diagnostic biomarker "TP53,HSPB1" cat "tissue,blood" breast cancer uncertain original research 28959337 Hspb1 and Tp53 Mutation and Expression Analysis in Cat Mammary Tumors. 261 mRNA diagnostic biomarker NDRG2 human uncertain bladder cancer L original research 28953854 Expression of N-Myc Downstream-Regulated Gene 2 in Bladder Cancer and Its Potential Utility as a Urinary Diagnostic Biomarker. 262 mRNA diagnostic biomarker "CBX5,SUV39H1,H3K9" human uncertain glioma H original research 28946550 HP1α is highly expressed in glioma cells and facilitates cell proliferation and survival. 263 mRNA diagnostic biomarker "HMLH1,HMSH2,HMSH6,PMS1,PMS2" human tissue ovarian cancer uncertain original research 28927094 Genomic markers of ovarian adenocarcinoma and its relevancy to the effectiveness of chemotherapy. 264 mRNA diagnostic biomarker "CASR,CXCL12,SST" human tissue gastric cancer uncertain original research 28914394 Bioinformatics-Based Identification of Methylated-Differentially Expressed Genes and Related Pathways in Gastric Cancer. 265 mRNA diagnostic biomarker KIR3DL2 human uncertain lymphoma H review 28912774 Therapeutic Antibodies to KIR3DL2 and Other Target Antigens on Cutaneous T-Cell Lymphomas. 266 mRNA diagnostic biomarker GREB1 human uncertain breast cancer H original research 28911214 Growth regulation by estrogen in breast cancer 1 (GREB1) is a novel progesterone-responsive gene required for human endometrial stromal decidualization. 267 mRNA diagnostic biomarker ATF6 human tissue colorectal cancer H original research 28884228 Expression of ATF6 as a marker of pre-cancerous atypical change in ulcerative colitis-associated colorectal cancer: a potential role in the management of dysplasia. 268 mRNA diagnostic biomarker CA9 human plasma pancreatic cancer H(CA19-9) original research 28874546 Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers. 269 mRNA diagnostic biomarker SSTR2 mice "tissue,blood,cell" gastric cancer uncertain original research 28859856 Gastrin Induces Nuclear Export and Proteasome Degradation of Menin in Enteric Glial Cells. 270 mRNA diagnostic biomarker FTO human tissue gastric cancer H original research 28849183 FTO expression is associated with the occurrence of gastric cancer and prognosis. 271 mRNA diagnostic biomarker PSCA human tissue prostate cancer H original research 28845520 PSCA regulates IL-6 expression through p38/NF-κB signaling in prostate cancer. 272 mRNA diagnostic biomarker PRSS3 human uncertain hepatocellular cancer L original research 28844099 Epigenetic silencing of PRSS3 provides growth and metastasis advantage for human hepatocellular carcinoma. 273 mRNA diagnostic biomarker DSG3 human tissue lung cancer H original research 28821283 Gene expression profiling of idiopathic interstitial pneumonias (IIPs): identification of potential diagnostic markers and therapeutic targets. 274 mRNA diagnostic biomarker "NEK2,DLGAP5,ECT2" human tissue lung cancer H original research 28808310 "Genome-scale analysis identifies NEK2, DLGAP5 and ECT2 as promising diagnostic and prognostic biomarkers in human lung cancer." 275 mRNA diagnostic biomarker PLAG1I human uncertain pleomorphic adenoma H original research 28796899 PLAG1 immunohistochemistry is a sensitive marker for pleomorphic adenoma: a comparative study with PLAG1 genetic abnormalities. 276 mRNA diagnostic biomarker "CAD,CCND1,ATM,RB1,MET,EGFR,ACTA1,SST,ESR1,DNM2" human uncertain colorectal cancer "H(CAD,CCND1,ATM,RB1,MET),L(EGFR,ACTA1,SST,ESR1,DNM2)" original research 28794688 Aberrantly methylated-differentially expressed genes and pathways in colorectal cancer. 277 mRNA diagnostic biomarker "ALDH1A1,ALDH1B1,ALDH1L1" human "tissue,serum" hepatocellular cancer L original research 28792511 Aldehyde dehydrogenase 1 (ALDH1) isoform expression and potential clinical implications in hepatocellular carcinoma. 278 mRNA diagnostic biomarker PCDH8 human tissue prostate cancer L original research 28789392 Association between protocadherin 8 promoter hypermethylation and the pathological status of prostate cancer. 279 mRNA diagnostic biomarker HOXA13 human tissue prostate cancer H original research 28766961 HOXA13 is associated with unfavorable survival and acts as a novel oncogene in prostate carcinoma. 280 mRNA diagnostic biomarker "IDH1,IDH2,ATRX" human uncertain glioma uncertain original research 28755323 Detection of the alternative lengthening of telomeres pathway in malignant gliomas for improved molecular diagnosis. 281 mRNA diagnostic biomarker "FAM134B,KIF2C,ALCAM,KIF1A" human uncertain breast cancer L original research 28754978 Integrated diagnostic network construction reveals a 4-gene panel and 5 cancer hallmarks driving breast cancer heterogeneity. 282 mRNA diagnostic biomarker SERBP1P2 human tissue ovarian cancer H original research 28738361 "Expression, Intracellular Localization, and Prognostic Value of Plasminogen Activator Inhibitor 1 and PAI-1 RNA-Binding Protein 1 in Primary and Recurrent Ovarian Cancer: A Study of the Tumor Bank Ovarian Cancer Network." 283 mRNA diagnostic biomarker LHX3 human tissue lung cancer non-small cell lung cancer H original research 28731174 LHX3 is an early stage and radiosensitivity prognostic biomarker in lung adenocarcinoma. 284 mRNA diagnostic biomarker MALAT1 human tissue gastric cancer H original research 28731043 Gastroblastoma harbors a recurrent somatic MALAT1-GLI1 fusion gene. 285 mRNA diagnostic biomarker CD274 human tissue breast cancer triple-negative breast cancer L(BRCA1) original research 28721372 Prevalence and predictors of androgen receptor and programmed death-ligand 1 in BRCA1-associated and sporadic triple-negative breast cancer. 286 mRNA diagnostic biomarker "UPB1,SOCS2,RTN3" human uncertain hepatocellular cancer "H(RTN3),L(UPB1,SOCS2)" original research 28717245 Development and Validation of a Three-gene Prognostic Signature for Patients with Hepatocellular Carcinoma. 287 mRNA diagnostic biomarker "MYC,TP53" human "tissue,serum" hepatocellular cancer H original research 28705056 Combined use of nuclear phosphoprotein c-Myc and cellular phosphoprotein p53 for hepatocellular carcinoma detection in high-risk chronic hepatitis C patients. 288 mRNA diagnostic biomarker "LGALS4,PTPRN2,TMPRSS11E,TRIM31,KCND3" human tissue bladder cancer H original research 28693282 Identification of hub genes and pathways associated with bladder cancer based on co-expression network analysis. 289 mRNA diagnostic biomarker UCK2 human tissue breast cancer H original research 28690649 Overexpression of Uridine-Cytidine Kinase 2 Correlates with Breast Cancer Progression and Poor Prognosis. 290 mRNA diagnostic biomarker ERVK6 human tissue pancreatic cancer H original research 28679769 Downregulation of Human Endogenous Retrovirus Type K (HERV-K) Viral env RNA in Pancreatic Cancer Cells Decreases Cell Proliferation and Tumor Growth. 291 mRNA diagnostic biomarker PARK7 human "tissue,serum" lung cancer "H(the early stage),L(the latter stage)" original research 28653888 DJ-1 as a potential biomarker for the early diagnosis in lung cancer patients. 292 mRNA diagnostic biomarker MMRN1 human tissue lung cancer H(TNC ) original research 28652369 Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival. 293 mRNA diagnostic biomarker POT1 human tissue gallbladder cancer H original research 28643740 Telomere length variation and expression analysis of shelterin complex genes during gallbladder carcinogenesis. 294 mRNA diagnostic biomarker S100A7 human tissue breast cancer H original research 28629450 Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment. 295 mRNA diagnostic biomarker PTGS2 human tissue gastric cancer "H(RhoA,COX-2)" original research 28624843 "Expressions of Ras Homolog Gene Family, Member A (RhoA) and Cyclooxygenase-2 (COX-2) Proteins in Early Gastric Cancer and Their Role in the Development of Gastric Cancer." 296 mRNA diagnostic biomarker "CBX5,H3K9" human tissue glioma "L(HP1α,H3K9me3)" original research 28623138 HP1α is highly expressed in glioma cells and facilitates cell proliferation and survival. 297 mRNA diagnostic biomarker TP53 human uncertain colorectal cancer H original research 28621756 p53 Expression as a Diagnostic Biomarker in Ulcerative Colitis-Associated Cancer. 298 mRNA diagnostic biomarker SALL3 human tissue head and neck cancer L original research 28616099 Epigenetic silencing of SALL3 is an independent predictor of poor survival in head and neck cancer. 299 mRNA diagnostic biomarker CCN3 human serum colorectal cancer H original research 28596563 The performance of the SEPT9 gene methylation assay and a comparison with other CRC screening tests: A meta-analysis. 300 mRNA diagnostic biomarker PINX1 human tissue breast cancer L original research 28586040 Low expression of PinX1 is associated with malignant behavior in basal-like breast cancer. 301 mRNA diagnostic biomarker SMARCA4 human uncertain lung cancer non-small cell lung cancer L original research 28555282 "SMARCA4-deficient pulmonary adenocarcinoma: clinicopathological, immunohistochemical, and molecular characteristics of a novel aggressive neoplasm with a consistent TTF1neg/CK7pos/HepPar-1pos immunophenotype." 302 mRNA diagnostic biomarker HOXB13 human uncertain prostate cancer uncertain original research 28555048 "Sensitivity of HOXB13 as a Diagnostic Immunohistochemical Marker of Prostatic Origin in Prostate Cancer Metastases: Comparison to PSA, Prostein, Androgen Receptor, ERG, NKX3.1, PSAP, and PSMA." 303 mRNA diagnostic biomarker PVHL human tissue tongue cancer H original research 28549422 Expression of von Hippel-Lindau tumor suppressor protein (pVHL) characteristic of tongue cancer and proliferative lesions in tongue epithelium. 304 mRNA diagnostic biomarker SFRP1 human uncertain lung cancer non-small cell lung cancer L original research 28545308 Secreted frizzled-related protein 1 (SFRP1) gene methylation changes in the human lung adenocarcinoma cells treated with L-securinine. 305 mRNA diagnostic biomarker PIWIL2 human tissue glioma H original research 28534979 "High expression of PIWIL2 promotes tumor cell proliferation, migration and predicts a poor prognosis in glioma." 306 mRNA diagnostic biomarker DEK human uncertain uncertain uncertain review 28530531 The Complexity of DEK Signaling in Cancer Progression. 307 mRNA diagnostic biomarker HOXA7 human tissue oral cancer oral squamous cell cancer H review 28529281 The expression and significance of the HOXA7 gene in oral squamous cell carcinoma. 308 mRNA diagnostic biomarker IGFBP3 human tissue colorectal cancer L review 28521493 "Clinicopathological significance and impact on outcomes of the gene expression levels of IGF-1, IGF-2 and IGF-1R, IGFBP-3 in patients with colorectal cancer: Overexpression of the IGFBP-3 gene is an effective predictor of outcomes in patients with colorectal cancer." 309 mRNA diagnostic biomarker ECOG human uncertain urothelial cancer uncertain review 28493171 Immunotherapy in Urothelial Cancer: Recent Results and Future Perspectives. 310 mRNA diagnostic biomarker "PSMA7,ITGA6,ITGB4,APP" human uncertain head and neck cancer H original research 28490889 Identification of potential biomarkers and analysis of prognostic values in head and neck squamous cell carcinoma by bioinformatics analysis. 311 mRNA diagnostic biomarker "CENPA,KRAS" human uncertain colorectal cancer L original research 28486948 Associating transcriptional modules with colon cancer survival through weighted gene co-expression network analysis. 312 mRNA diagnostic biomarker HCLP46 human tissue colorectal cancer H review 28481732 Human CAP10-Like Protein 46 kDa Gene Promotes Malignancy in Colorectal Cancer. 313 mRNA diagnostic biomarker RKIP human "tissue,plasma" myeloma multiple myeloma L review 28476134 Overexpression of RKIP and its cross-talk with several regulatory gene products in multiple myeloma. 314 mRNA diagnostic biomarker "CD44,POU5F1" human tissue pancreatic cancer H original research 28464601 Discrimination of CD44 and Oct3/4 Expression in Pancreatic Adenocarcinoma from Benign Pancreatic Ducts in Small Biopsy Specimens. 315 mRNA diagnostic biomarker "GTF2I,BRAF" human uncertain astrocytoma pilocytic astrocytoma H original research 28448514 A new GTF2I-BRAF fusion mediating MAPK pathway activation in pilocytic astrocytoma. 316 mRNA diagnostic biomarker GPC1 human tissue pancreatic cancer H original research 28440066 Elevated glypican-1 expression is associated with an unfavorable prognosis in pancreatic ductal adenocarcinoma. 317 mRNA diagnostic biomarker PCGF2 human tissue esophageal cancer esophageal squamous cell cancer "H(Bmi-1),L(Mel-18)" original research 28425347 Expression and Clinicopathological Significance of Mel-18 and Bmi-1 in Esophageal Squamous Cell Carcinoma. 318 mRNA diagnostic biomarker "CAP1,CAP2" human tissue prostate cancer H(CAP1) original research 28423713 Systematic analysis of gene expression alterations and clinical outcomes of adenylate cyclase-associated protein in cancer. 319 mRNA diagnostic biomarker LCP1 human tissue bladder cancer H(SLP-76) original research 28423532 Implication of vascular endothelial growth factor A and C in revealing diagnostic lymphangiogenic markers in node-positive bladder cancer. 320 mRNA diagnostic biomarker ANXA13 human uncertain colorectal cancer H original research 28423508 Annexin A13 promotes tumor cell invasion in vitro and is associated with metastasis in human colorectal cancer. 321 mRNA diagnostic biomarker "FASN,HPIN" human tissue prostate cancer H original research 28418352 Fatty acid synthase in the diagnosis of prostate neoplasms. 322 mRNA diagnostic biomarker DPEP1 human tissue colorectal cancer H original research 28413640 Clinicopathological examination of dipeptidase 1 expression in colorectal cancer. 323 mRNA diagnostic biomarker RPS4X human tissue breast cancer "H(BC10-1,BC13-4)" original research 28410206 Development of diagnostic SCAR markers for genomic DNA amplifications in breast carcinoma by DNA cloning of high-GC RAMP-PCR fragments. 324 mRNA diagnostic biomarker EMP3 human uncertain uncertain H review 28408326 "EMP1, EMP 2, and EMP3 as novel therapeutic targets in human cancer." 325 mRNA diagnostic biomarker RASSF1A human tissue nasopharyngeal cancer H original research 28396012 "Diagnostic Capacity of RASSF1A Promoter Methylation as a Biomarker in Tissue, Brushing, and Blood Samples of Nasopharyngeal Carcinoma." 326 mRNA diagnostic biomarker "ATG12,FYCO1,ULK1,TECPR1" human tissue bladder cancer L original research 28381171 Identification and validation of a novel autophagy gene expression signature for human bladder cancer patients. 327 mRNA diagnostic biomarker "INI1,SMARCB1" human uncertain nerve sheath tumor L original research 28365909 A mosaic pattern of INI1/SMARCB1 protein expression distinguishes Schwannomatosis and NF2-associated peripheral schwannomas from solitary peripheral schwannomas and NF2-associated vestibular schwannomas. 328 mRNA diagnostic biomarker TNC human tissue prostate cancer H original research 28341124 Tenascin-C is a potential cancer-associated fibroblasts marker and predicts poor prognosis in prostate cancer. 329 mRNA diagnostic biomarker "VEZT,G3BP1" human tissue gastric cancer L original research 28337362 Analysis of G3BP1 and VEZT Expression in Gastric Cancer and Their Possible Correlation with Tumor Clinicopathological Factors. 330 mRNA diagnostic biomarker HERG human uncertain uncertain uncertain review 28334543 Functional impact of hERG: from physiological role to target of anticancer therapy. 331 mRNA diagnostic biomarker SPP1 human "tissue,serum" leukemia; lymphoma;osteosarcoma H review 28326824 Osteopontin: its potential role in cancer of children and young adults. 332 mRNA diagnostic biomarker EWSR1 human uncertain gastrointestinal cancer gastrointestinal neuroectodermal tumor uncertain original research 28320420 Malignant gastrointestinal neuroectodermal tumor: a case report and review of the literature. 333 mRNA diagnostic biomarker "BIRC5,E2F1,CCNE1,CDKN2A" human uncertain hepatocellular cancer H original research 28316892 From big data to diagnosis and prognosis: gene expression signatures in liver hepatocellular carcinoma. 334 mRNA diagnostic biomarker UBE2C human uncertain gastric cancer H original research 28260026 UBE2C induces EMT through Wnt/β‑catenin and PI3K/Akt signaling pathways by regulating phosphorylation levels of Aurora-A. 335 mRNA diagnostic biomarker "GPC3,IGFL2" human tissue hepatocellular cancer H original research 28240019 Differential Expression of Glypican-3 and Insulin–Like Growth Factor-II mRNAs and Alpha-Fetoprotein and Ki-67 Markers in HCV Related Hepatocellular Carcinomas In Egyptian Patients 336 mRNA diagnostic biomarker "AGR2,POSTN,ANXA1,STMN1,COF1,PAIRBP1,TSP2,ACTN4" human uncertain breast cancer "H(STMN1,COF1,PAIRBP1,TSP2,POSTN)" original research 28216224 Targeted proteomics driven verification of biomarker candidates associated with breast cancer aggressiveness. 337 mRNA diagnostic biomarker PTEN human uncertain breast cancer H original research 28213783 High PTEN gene expression is a negative prognostic marker in human primary breast cancers with preserved p53 function. 338 mRNA diagnostic biomarker GATA3 human uncertain breast cancer triple-negative breast cancer H original research 28211079 GATA3 expression in triple-negative breast cancers. 339 mRNA diagnostic biomarker "EGFR,PRKX,PDGFB,PIK3R3,SLK,IGF1,CDC42,PRKCA" human uncertain lung cancer uncertain original research 28204826 Pathway deviation-based biomarker and multi-effect target identification in asbestos-related squamous cell carcinoma of the lung. 340 mRNA diagnostic biomarker "CFTR,SCTR,FIGF" human tissue lung cancer lung squamous cell carcinoma L original research 28203405 Weighted gene co-expression network analysis in identification of metastasis-related genes of lung squamous cell carcinoma based on the Cancer Genome Atlas database. 341 mRNA diagnostic biomarker MMKI67 human tissue breast cancer uncertain original research 28193205 "Comparison of immunohistochemistry with PCR for assessment of ER, PR, and Ki-67 and prediction of pathological complete response in breast cancer." 342 mRNA diagnostic biomarker HMGN4 human uncertain thyroid cancer H original research 28186538 Elevated HMGN4 expression potentiates thyroid tumorigenesis. 343 mRNA diagnostic biomarker QRSL1 human uncertain breast cancer uncertain original research 28171879 Male Breast Cancer. 344 mRNA diagnostic biomarker TMEM39A human tissue "glioma,brain tumor" H original research 28133515 Recognition of Transmembrane Protein 39A as a Tumor-Specific Marker in Brain Tumor. 345 mRNA diagnostic biomarker "BRCA1,GSTP1" human tissue breast cancer L original research 28105221 Aberrant promoter methylation of cancer-related genes in human breast cancer. 346 mRNA diagnostic biomarker LRG1 human tissue head and neck cancer head and neck squamous cell carcinoma L original research 28098902 Downregulation of leucine‑rich‑α‑2‑glycoprotein 1 expression is associated with the tumorigenesis of head and neck squamous cell carcinoma. 347 mRNA diagnostic biomarker "SNRPN,PEG10,MEST" human plasma uncertain chorio cancer H original research 28098215 "Epigenetic modifications at DMRs of placental genes are subjected to variations in normal gestation, pathological conditions and folate supplementation." 348 mRNA diagnostic biomarker IQGAP3 human tissue pancreatic cancer H original research 28078013 Overexpression and biological function of IQGAP3 in human pancreatic cancer. 349 mRNA diagnostic biomarker "ETV6,NTRK3" human uncertain secretory cancer mammary analogue secretory carcinoma uncertain original research 28072974 Clinicopathologic features of mammary analogue secretory carcinoma of salivary glands. 350 mRNA diagnostic biomarker KCNH1 human serum breast cancer H original research 28070819 Inducing Polyclonal Eag1-Specific Antibodies by Vaccination with a Linear Epitope Immunogen and Its Relation to Breast Tumorigenesis. 351 mRNA diagnostic biomarker EGR human "tissue,serum" prostate cancer H original research 28061466 Prostate cancer proteomics: Current trends and future perspectives for biomarker discovery. 352 mRNA diagnostic biomarker BAP1 human uncertain mesothelioma pleural mesothelioma L original research 28034829 "BAP1 Is Altered by Copy Number Loss, Mutation, and/or Loss of Protein Expression in More Than 70% of Malignant Peritoneal Mesotheliomas." 353 mRNA diagnostic biomarker "JMJD7,PLA2G4B" human uncertain head and neck cancer head and neck squamous cell carcinoma H original research 28030848 A novel read-through transcript JMJD7-PLA2G4B regulates head and neck squamous cell carcinoma cell proliferation and survival. 354 mRNA diagnostic biomarker "CAS,CSE1L" human tissue esophageal cancer H original research 27941559 "Expression of CAS/CSE1L, the Cellular Apoptosis Susceptibility Protein, Correlates With Neoplastic Progression in Barrett's Esophagus." 355 mRNA diagnostic biomarker "STAT1,EGFR2" human uncertain gastric cancer "H(CIT,PRC1,TTK,KIF14)" original research 27923621 Transcriptomic analysis of gene expression profiles of stomach carcinoma reveal abnormal expression of mitotic components. 356 mRNA diagnostic biomarker IgSF human uncertain breast cancer H original research 27911271 Immunoglobulin superfamily genes are novel prognostic biomarkers for breast cancer. 357 mRNA diagnostic biomarker MET human uncertain renal cancer clear cell renal cell carcinoma H original research 27894094 MET expression and copy number status in clear-cell renal cell carcinoma: prognostic value and potential predictive marker. 358 mRNA diagnostic biomarker AJUBA human uncertain colorectal cancer H review 27893714 The LIM protein AJUBA promotes colorectal cancer cell survival through suppression of JAK1/STAT1/IFIT2 network. 359 mRNA diagnostic biomarker CICDUX4 human uncertain cell cancer uncertain original research 27879517 DUX4 Immunohistochemistry Is a Highly Sensitive and Specific Marker for CIC-DUX4 Fusion-positive Round Cell Tumor. 360 mRNA diagnostic biomarker TYK2 human tissue neurofibroma uncertain original research 27875628 Clinical genomic profiling identifies TYK2 mutation and overexpression in patients with neurofibromatosis type 1-associated malignant peripheral nerve sheath tumors. 361 mRNA diagnostic biomarker SALL4 human tissue lung cancer H original research 27867542 "The expression of SALL4 is significantly associated with EGFR, but not KRAS or EML4-ALK mutations in lung cancer." 362 mRNA diagnostic biomarker "S100A9,GRN" human tissue hepatocellular cancer H review 27847095 Proteomic analysis and translational perspective of hepatocellular carcinoma: Identification of diagnostic protein biomarkers by an onco-proteogenomics approach. 363 mRNA diagnostic biomarker "MUC1,MUC4" human uncertain uncertain uncertain review 27838635 Genetic variants of mucins: unexplored conundrum. 364 mRNA diagnostic biomarker COL1A1 human tissue thymic cancer uncertain original research 27832160 Proteomic Signatures of Thymomas. 365 mRNA diagnostic biomarker MTA2 human tissue cervical cancer squamous cervical cancer H original research 27807324 Expression of metastasis tumor-associated protein 2 in cervical squamous carcinoma and its relationship with prognosis. 366 mRNA diagnostic biomarker CREB1 human uncertain colorectal cancer H original research 27801665 CREB1 directly activates the transcription of ribonucleotide reductase small subunit M2 and promotes the aggressiveness of human colorectal cancer. 367 mRNA diagnostic biomarker HSPA5 human tissue breast cancer inflammatory breast carcinoma uncertain original research 27791177 Towards a transcriptome-based theranostic platform for unfavorable breast cancer phenotypes. 368 mRNA diagnostic biomarker MYC human tissue sarcoma angiosarcoma H original research 27780597 MYC immunohistochemistry in angiosarcoma and atypical vascular lesions: practical considerations based on a single institutional experience. 369 mRNA diagnostic biomarker SKP2 human tissue hepatocellular cancer H original research 27779207 HBV core promoter mutations and AKT upregulate S-phase kinase-associated protein 2 to promote postoperative hepatocellular carcinoma progression. 370 mRNA diagnostic biomarker TCN human tissue "hepatocellular cancer,lung cancer" H original research 27771326 Identification of a TSPY co-expression network associated with DNA hypomethylation and tumor gene expression in somatic cancers. 371 mRNA diagnostic biomarker "ERCC1,TNIP1,ERCC1,DPYD,ERBB2" human "tissue,cell" esophageal cancer esophageal squamous cell cancer H(ERBB2) original research 27741011 Molecular Markers for the Prediction of Minor Response to Neoadjuvant Chemoradiation in Esophageal Cancer: Results of the Prospective Cologne Esophageal Response Prediction (CERP) Study. 372 mRNA diagnostic biomarker "CA9,TNFAIP6" human tissue renal cancer clear cell renal cell carcinoma H(CA9) original research 27739342 Development and confirmation of potential gene classifiers of human clear cell renal cell carcinoma using next-generation RNA sequencing. 373 mRNA diagnostic biomarker SFRP2 human uncertain colorectal cancer uncertain review 27721248 Diagnostic value of secreted frizzled-related protein 2 gene promoter hypermethylation in stool for colorectal cancer: A meta-analysis. 374 mRNA diagnostic biomarker RGS6 human uncertain bladder cancer L original research 27713144 RGS6 is an essential tumor suppressor that prevents bladder carcinogenesis by promoting p53 activation and DNMT1 downregulation. 375 mRNA diagnostic biomarker RAGE human tissue breast cancer H original research 27710974 Increased Expression of the Receptor for Advanced Glycation End-Products (RAGE) Is Associated with Advanced Breast Cancer Stage. 376 mRNA diagnostic biomarker FOXM1 human tissue Wilms' tumor H original research 27698870 Association of FOXM1 expression with tumor histology and prognosis in Wilms tumor: Potential for a new prognostic marker. 377 mRNA diagnostic biomarker "SPATS2,ST6GALNAC1" human tissue lung cancer uncertain original research 27681076 Novel biomarkers that assist in accurate discrimination of squamous cell carcinoma from adenocarcinoma of the lung. 378 mRNA diagnostic biomarker EGFR human uncertain lung cancer non-small cell lung cancer uncertain original research 27669169 Genetic Modifiers of Progression-Free Survival in Never-Smoking Lung Adenocarcinoma Patients Treated with First-Line Tyrosine Kinase Inhibitors. 379 mRNA diagnostic biomarker FRK human tissue cervical cancer L original research 27665472 Fyn-related kinase expression predicts favorable prognosis in patients with cervical cancer and suppresses malignant progression by regulating migration and invasion. 380 mRNA diagnostic biomarker "IDH1,IDH2" human tissue glioma H original research 27664011 Mutant IDH1 and thrombosis in gliomas. 381 mRNA diagnostic biomarker ANXA3 human "tissue,serum" colorectal cancer H original research 27661117 High-throughput proteomics integrated with gene microarray for discovery of colorectal cancer potential biomarkers. 382 mRNA diagnostic biomarker SFRP2 human uncertain colorectal cancer H original research 27659069 Methylation of SFRP2 gene as a promising noninvasive biomarker using feces in colorectal cancer diagnosis: a systematic meta-analysis. 383 mRNA diagnostic biomarker ESRP1 human tissue colorectal cancer L original research 27650542 Epithelial splicing regulatory protein 1 and 2 paralogues correlate with splice signatures and favorable outcome in human colorectal cancer. 384 mRNA diagnostic biomarker FOSB human tissue gastric cancer L original research 27633497 Abnormal expression of FOSB correlates with tumor progression and poor survival in patients with gastric cancer. 385 mRNA diagnostic biomarker PRMT1 human "tissue,cell" esophageal cancer esophageal squamous cell cancer H original research 27621578 Protein and gene expression characteristics of heterogeneous nuclear ribonucleoprotein H1 in esophageal squamous cell carcinoma. 386 mRNA diagnostic biomarker EWSR1 human uncertain desmoplastic small round cell tumor uncertain review 27621277 "Desmoplastic Small Round Cell Tumor: Pathology, Genetics, and Potential Therapeutic Strategies." 387 mRNA diagnostic biomarker ERCC1 human tissue uncertain uncertain original research 27610644 Development and Validation of an ERCC1 Immunohistochemistry Assay for Solid Tumors. 388 mRNA diagnostic biomarker NEU1 human tissue hepatocellular cancer H original research 27602751 Neuraminidase 1 (NEU1) promotes proliferation and migration as a diagnostic and prognostic biomarker of hepatocellular carcinoma. 389 mRNA diagnostic biomarker SNCG human uncertain breast cancer H original research 27595752 Overexpression of synuclein-γ predicts lack of benefit from radiotherapy for breast cancer patients. 390 mRNA diagnostic biomarker "WT1,CALB2,CEA,CLDN4" human uncertain mesothelioma uncertain original research 27589012 Utility and pitfalls of immunohistochemistry in the differential diagnosis between epithelioid mesothelioma and poorly differentiated lung squamous cell carcinoma. 391 mRNA diagnostic biomarker UBE2C human tissue esophageall cancer esophageal squamous cell cancer H original research 27588470 UBE2C is overexpressed in ESCC tissues and its abrogation attenuates the malignant phenotype of ESCC cell lines. 392 mRNA diagnostic biomarker "GNG2,AGT,SAA1,ADCY5,LPAR1,NMU,CXCL8,CXCL12,GNAI1,CCR2" human uncertain colorectal cancer uncertain original research 27581154 Identification of key pathways and genes in colorectal cancer using bioinformatics analysis. 393 mRNA diagnostic biomarker FAM129A human tissue prostate cancer L original research 27578825 Whole blood mRNA in prostate cancer reveals a four-gene androgen regulated panel. 394 mRNA diagnostic biomarker CD151 human blood esophageall cancer L original research 27577713 CD151 Gene and Protein Expression Provides Independent Prognostic Information for Patients with Adenocarcinoma of the Esophagus and Gastroesophageal Junction Treated by Esophagectomy. 395 mRNA diagnostic biomarker ILK human uncertain bladder cancer L original research 27576342 Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways. 396 mRNA diagnostic biomarker HMLH1 human tissue lung cancer non-small cell lung cancer L original research 27574449 The clinicopathological significance of hMLH1 hypermethylation in non-small-cell lung cancer: a meta-analysis and literature review. 397 mRNA diagnostic biomarker MTA human tissue gastric cancer H(MTA1) original research 27574100 Metastasis-associated protein is a predictive biomarker for metastasis and recurrence in gastric cancer. 398 mRNA diagnostic biomarker FHIT human tissue lung cancer non-small cell lung cancer H original research 27572663 "FHIT promoter methylation status, low protein and high mRNA levels in patients with non-small cell lung cancer." 399 mRNA diagnostic biomarker "MYB,CD117" human uncertain pleomorphic adenoma H(HMGA2) review 27567603 Unusual pleomorphic adenoma of the lacrimal Gland: Immunohistochemical demonstration of PLAG1 and HMGA2 oncoproteins. 400 mRNA diagnostic biomarker SRSF5 human tissue lung cancer H(SRSF5-7) original research 27565915 SRSF5: a novel marker for small-cell lung cancer and pleural metastatic cancer. 401 mRNA diagnostic biomarker ITGB1 human tissue thyroid cancer H(Hur) original research 27542231 Identification of tumorigenesis-related mRNAs associated with RNA-binding protein HuR in thyroid cancer cells. 402 mRNA diagnostic biomarker "TLR9,NFKBIA" human tissue glioma "H(TLR9),L(NFKBIA)" original research 27538656 Predictive and prognostic value of TLR9 and NFKBIA gene expression as potential biomarkers for human glioma diagnosis. 403 mRNA diagnostic biomarker ROS1f human tissue lung cancer non-small cell lung cancer H original research 27535289 Testing for ROS1 in non-small cell lung cancer: a review with recommendations. 404 mRNA diagnostic biomarker WNT2 human tissue cervical cancer H original research 27513465 WNT2 Promotes Cervical Carcinoma Metastasis and Induction of Epithelial-Mesenchymal Transition. 405 mRNA diagnostic biomarker WT1 human blood leukaemia H original research 27512765 Wilms’ Tumor Gene (WT1) Expression and Minimal Residual Disease in Acute Myeloid Leukemia. 406 mRNA diagnostic biomarker KAI1 human tissue breast cancer L original research 27509988 Expression Levels of Tetraspanin KAI1/CD82 in Breast Cancers in North Indian Females. 407 mRNA diagnostic biomarker KRT19 human tissue thyroid cancer L original research 27504290 Expression of Cytokeratin-19 and Thyroperoxidase in Relation to Morphological Features in Non-Neoplastic and Neoplastic Lesions of Thyroid. 408 mRNA diagnostic biomarker "PRAME,CTAG1B" human tissue liposarcoma myxoid liposarcoma H original research 27499900 Cancer-testis antigens PRAME and NY-ESO-1 correlate with tumour grade and poor prognosis in myxoid liposarcoma. 409 mRNA diagnostic biomarker "ANXA4,FLNA" human tissue oral cancer oral squamous cell cancer uncertain original research 27485544 Quantitative proteomic analysis for novel biomarkers of buccal squamous cell carcinoma arising in background of oral submucous fibrosis. 410 mRNA diagnostic biomarker SATB1 human tissue colorectal cancer H original research 27466515 Identification of SATB1 as a Specific Biomarker for Lymph Node Metastasis in Colorectal Cancer. 411 mRNA diagnostic biomarker SPDYE6 mice uncertain cervical cancer uncertain original research 27465494 "Production of functional, stable, unmutated recombinant human papillomavirus E6 oncoprotein: implications for HPV-tumor diagnosis and therapy." 412 mRNA diagnostic biomarker PLAG1 human cell pleomorphic adenoma H original research 27463119 PLAG1: An Immunohistochemical Marker with Limited Utility in Separating Pleomorphic Adenoma from Other Basaloid Salivary Gland Tumors. 413 mRNA diagnostic biomarker EPCAM human uncertain craniopharyngioma H original research 27431859 EpCAM (CD326) is differentially expressed in craniopharyngioma subtypes and Rathke's cleft cysts. 414 mRNA diagnostic biomarker MAPK human uncertain thyroid cancer uncertain review 27423883 Intracellular signaling mechanisms in thyroid cancer. 415 mRNA diagnostic biomarker CEACAM7 human "tissue,plasma" gastric cancer H original research 27421133 CEACAM6 is upregulated by Helicobacter pylori CagA and is a biomarker for early gastric cancer. 416 mRNA diagnostic biomarker "WNT1,SFRP1" human tissue cutaneous cancer cutaneous squamous cell carcinoma "H(WNT1),L(SFRP1)" original research 27420949 Wnt1 and SFRP1 as potential prognostic factors and therapeutic targets in cutaneous squamous cell carcinoma. 417 mRNA diagnostic biomarker GSTM1 human "tissue,cell" "urothelial cancer,bladder cancer" L original research 27404495 Gene Expression and DNA Methylation Status of Glutathione S-Transferase Mu1 and Mu5 in Urothelial Carcinoma. 418 mRNA diagnostic biomarker MMP3 "rabbit,mice " serum breast cancer H original research 27404490 Development of recombinant matrix metalloproteinase-3 based sandwich ELISA for sero-diagnosis of canine mammary carcinomas. 419 mRNA diagnostic biomarker "PGR,MKI67" human uncertain meningioma "H(Ki67),L(PGR)" original research 27394131 "Expression of p40 (∆Np63) protein in meningiomas, an unexpected finding: immunohistochemical study and evaluation of its possible prognostic role." 420 mRNA diagnostic biomarker "KRT20,KRT19" human blood colorectal cancer H original research 27386436 "A Pilot Study of CK19, CK20 and GCC mRNA in the Peripheral Blood as a Colorectal Cancer Biomarker Panel." 421 mRNA diagnostic biomarker PLAG1 human uncertain pleomorphic adenoma recurrent pleomorphic adenoma H original research 27381214 PLAG1 expression is maintained in recurrent pleomorphic adenoma. 422 mRNA diagnostic biomarker RAB25 human uncertain oral cancer oral squamous cell cancer L original research 27379752 RAB25 expression is epigenetically downregulated in oral and oropharyngeal squamous cell carcinoma with lymph node metastasis. 423 mRNA diagnostic biomarker HPRT1 human uncertain uncertain uncertain original research 27335807 An international comparability study on quantification of mRNA gene expression ratios: CCQM-P103.1. 424 mRNA diagnostic biomarker "CD20,ECM,ITGA" human uncertain osteosarcoma "H(ECM,ITGA),L(CD20)" original research 27314445 "Identification of CD20, ECM, and ITGA as Biomarkers for Osteosarcoma by Integrating Transcriptome Analysis." 425 mRNA diagnostic biomarker ERG human urine prostate cancer uncertain original research 27299694 Amplification-Free Detection of Gene Fusions in Prostate Cancer Urinary Samples Using mRNA-Gold Affinity Interactions. 426 mRNA diagnostic biomarker MLH1 human blood colorectal cancer L original research 27294005 The mRNA level of MLH1 in peripheral blood is a biomarker for the diagnosis of hereditary nonpolyposis colorectal cancer. 427 mRNA diagnostic biomarker "PAX1,ZNF582,HPV16" human uncertain cervical cancer uncertain original research 27293491 Combined clinical and genetic testing algorithm for cervical cancer diagnosis. 428 mRNA diagnostic biomarker HOXB7 human tissue hepatocellular cancer H original research 27272787 HOXB7 Expression is a Novel Biomarker for Long-term Prognosis After Resection of Hepatocellular Carcinoma. 429 mRNA diagnostic biomarker "AMACR,ERG" human uncertain prostate cancer H original research 27271990 High alpha-methylacyl-CoA racemase (AMACR) is associated with ERG expression and with adverse clinical outcome in patients with localized prostate cancer. 430 mRNA diagnostic biomarker "C3,PPARG,PAX8,JUN,MMP9" human tissue thyroid cancer papillary thyroid carcinoma uncertain original research 27250077 Key genes and pathways predicted in papillary thyroid carcinoma based on bioinformatics analysis. 431 mRNA diagnostic biomarker HIF2 human tissue renal cancer clear cell renal cell carcinoma H original research 27244898 Opposite prognostic roles of HIF1α and HIF2α expressions in bone metastatic clear cell renal cell cancer. 432 mRNA diagnostic biomarker GATA3 human uncertain urothelial cancer H original research 27241168 GATA3 immunohistochemical expression in invasive urothelial carcinoma. 433 mRNA diagnostic biomarker PTEN human tissue prostate cancer L original research 27234536 "Alterations in PTEN, MDM2, TP53 and AR protein and gene expression are associated with canine prostate carcinogenesis." 434 mRNA diagnostic biomarker PAX1 human tissue uterine cancer endometrial cancer H original research 27226215 Paired boxed gene 1 expression: A single potential biomarker for differentiating endometrial lesions associated with favorable outcomes in patients with endometrial carcinoma. 435 mRNA diagnostic biomarker IFITM1 human tissue oral cancer oral squamous cell cancer H original research 27221933 Interferon Induced Transmembrane Protein-1 Gene Expression as a Biomarker for Early Detection of Invasive Potential of Oral Squamous Cell Carcinomas. 436 mRNA diagnostic biomarker PNPLA2 mice tissue uncertain L original research 27213586 Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia. 437 mRNA diagnostic biomarker "DLX1,RHOU" human tissue prostate cancer L original research 27196083 "Validation of Novel Biomarkers for Prostate Cancer Progression by the Combination of Bioinformatics, Clinical and Functional Studies." 438 mRNA diagnostic biomarker S100A4 human uncertain uncertain H original research 27193724 "The level of the Phf10 protein, a PBAF chromatin-remodeling complex subunit, correlates with the Mts1/S100A4 expression in human cancer cell lines." 439 mRNA diagnostic biomarker "HELLS,ZIC5" human tissue prostate cancer H(ZIC5) original research 27191985 Gene-expression analysis of gleason grade 3 tumor glands embedded in low- and high-risk prostate cancer. 440 mRNA diagnostic biomarker BPIFA1 human "tissue,plasma,blood" lung cancer non-small cell lung cancer H original research 27186415 "Plasma LUNX mRNA, a non-invasive specific biomarker for diagnosis and prognostic prediction of non-small cell lung cancer." 441 mRNA diagnostic biomarker HMGA2 human tissue urothelial cancer H original research 27186400 Overexpression and oncogenic function of HMGA2 in endometrial serous carcinogenesis. 442 mRNA diagnostic biomarker "WT1,PAX5,PAX6,PYCARD,GATA5" human tissue hepatocellular cancer H original research 27171388 "Aberrant methylation of tumour suppressor genes WT1, GATA5 and PAX5 in hepatocellular carcinoma." 443 mRNA diagnostic biomarker EGFR human tissue colorectal cancer H original research 27160084 Significant association and synergistic adverse prognostic effect of podocalyxin-like protein and epidermal growth factor receptor expression in colorectal cancer. 444 mRNA diagnostic biomarker "GP3,GP4" human tissue prostate cancer uncertain original research 27152194 Molecular characterization of Gleason patterns 3 and 4 prostate cancer using reverse Warburg effect-associated genes. 445 mRNA diagnostic biomarker ZNF545 human tissue myeloma multiple myeloma L original research 27150632 Epigenetic identification of ZNF545 as a functional tumor suppressor in multiple myeloma via activation of p53 signaling pathway. 446 mRNA diagnostic biomarker KRT20 human blood breast cancer H original research 27147896 Assessment of Cytokeratin-19 Gene Expression in Peripheral Blood of Breast Cancer Patients and Breast Cancer Cell Lines. 447 mRNA diagnostic biomarker "MIA,MIA2,TANGO" human tissue uncertain Multiple cancers H(MIA2) original research 27145272 "A comprehensive expression analysis of the MIA gene family in malignancies: MIA gene family members are novel, useful markers of esophageal, lung, and cervical squamous cell carcinoma." 448 mRNA diagnostic biomarker AQP1 human tissue cholangio cancer hilar cholangiocarcinoma H original research 27143047 Elevated AQP1 Expression Is Associated With Unfavorable Oncologic Outcome in Patients With Hilar Cholangiocarcinoma. 449 mRNA diagnostic biomarker BLAST human uncertain gastric cancer H original research 27127885 GCGene: a gene resource for gastric cancer with literature evidence. 450 mRNA diagnostic biomarker ECRG4 human tissue nasopharyngeal cancer L original research 27119734 Downregulated ECRG4 is correlated with lymph node metastasis and predicts poor outcome for nasopharyngeal carcinoma patients. 451 mRNA diagnostic biomarker HMGA2 human tissue esophageal cancer esophageal squamous cell cancer H original research 27119517 Clinicopathologic significance of HMGA2 expression's correlation with prognosis of esophageal squamous cell carcinoma after Ivor Lewis esophagectomy. 452 mRNA diagnostic biomarker DMGDH human uncertain hepatocellular cancer L original research 27119355 Potential diagnostic and prognostic marker dimethylglycine dehydrogenase (DMGDH) suppresses hepatocellular carcinoma metastasis in vitro and in vivo. 453 mRNA diagnostic biomarker HSPA8 human tissue uterine cancer endometrial cancer H original research 27110132 Identification of HSPA8 as a candidate biomarker for endometrial carcinoma by using iTRAQ-based proteomic analysis. 454 mRNA diagnostic biomarker "SAA1,CRP" human serum uncertain H(SAA1) review 27087246 Structure and Expression of Different Serum Amyloid A (SAA) Variants and their Concentration-Dependent Functions During Host Insults. 455 mRNA diagnostic biomarker BAP1 human tissue renal cancer clear cell renal cell carcinoma L original research 27085487 Loss of nuclear BAP1 protein expression is a marker of poor prognosis in patients with clear cell renal cell carcinoma. 456 mRNA diagnostic biomarker "CHN1,TNFAIP3" human uncertain esophageal cancer esophageal squamous cell cancer H original research 27072986 The Discovery and Validation of Biomarkers for the Diagnosis of Esophageal Squamous Dysplasia and Squamous Cell Carcinoma. 457 mRNA diagnostic biomarker EBNA1 human tissue nasopharyngeal cancer L original research 27071030 Characterization of the Variability of Epstein-Barr Virus Genes in Nasopharyngeal Biopsies: Potential Predictors for Carcinoma Progression. 458 mRNA diagnostic biomarker AKAP4 human serum colorectal cancer uncertain original research 27057472 A novel cancer testis antigen target A-kinase anchor protein (AKAP4) for the early diagnosis and immunotherapy of colon cancer. 459 mRNA diagnostic biomarker MYO6 human tissue colorectal cancer L original research 27044563 Downregulation of myosin VI reduced cell growth and increased apoptosis in human colorectal cancer. 460 mRNA diagnostic biomarker CD55 human tissue neuroblastoma H original research 27043658 CD55 is a HIF-2α marker with anti-adhesive and pro-invading properties in neuroblastoma. 461 mRNA diagnostic biomarker PRSS8 human "tissue,serum" ovarian cancer H original research 27036110 The serine protease prostasin (PRSS8) is a potential biomarker for early detection of ovarian cancer. 462 mRNA diagnostic biomarker ERBB human uncertain breast cancer H review 27016130 Interplay between steroid hormone activation of the unfolded protein response and nuclear receptor action. 463 mRNA diagnostic biomarker GT198 human uncertain breast cancer uncertain original research 27001628 GT198 Expression Defines Mutant Tumor Stroma in Human Breast Cancer. 464 mRNA diagnostic biomarker YTHDC2 human tissue colon cancer H original research 26996300 RNA helicase YTHDC2 promotes cancer metastasis via the enhancement of the efficiency by which HIF-1α mRNA is translated. 465 mRNA diagnostic biomarker DLC1 human uncertain breast cancer L original research 26986853 rs621554 single nucleotide polymorphism of DLC1 is associated with breast cancer susceptibility and prognosis. 466 mRNA diagnostic biomarker REG4 human "tissue,serum" ovarian cancer H original research 26981633 REG4 Is Highly Expressed in Mucinous Ovarian Cancer: A Potential Novel Serum Biomarker. 467 mRNA diagnostic biomarker ERG human uncertain prostate cancer prostatic intraepithelial neoplasia uncertain original research 26978019 Diagnostic value of estimation of ERG expression in prostate adenocarcinoma and high-grade prostatic intraepithelial neoplasia. 468 mRNA diagnostic biomarker NUCKS1 human tissue hepatocellular cancer H original research 26968889 Identification of NUCKS1 as a putative oncogene and immunodiagnostic marker of hepatocellular carcinoma. 469 mRNA diagnostic biomarker DNMT human uncertain oral cancer oral squamous cell cancer H original research 26966018 Prognostic value of the DNMTs mRNA expression and genetic polymorphisms on the clinical outcome in oral cancer patients. 470 mRNA diagnostic biomarker CREBBP human uncertain uncertain H review 26934558 Control of CREB expression in tumors: from molecular mechanisms and signal transduction pathways to therapeutic target. 471 mRNA diagnostic biomarker SLC18A2 human tissue pancreatic cancer L original research 26905753 Large-scale evaluation of SLC18A2 in prostate cancer reveals diagnostic and prognostic biomarker potential at three molecular levels. 472 mRNA diagnostic biomarker RBBP6 human tissue colon cancer L original research 26905308 Expression analysis and association of RBBP6 with apoptosis in colon cancers. 473 mRNA diagnostic biomarker USO1 human tissue myeloma H original research 26898451 USO1 promotes tumor progression via activating Erk pathway in multiple myeloma cells. 474 mRNA diagnostic biomarker TUSC3 human uncertain pancreatic cancer L original research 26871953 "Decreased TUSC3 Promotes Pancreatic Cancer Proliferation, Invasion and Metastasis." 475 mRNA diagnostic biomarker PCA3 human uncertain prostate cancer H original research 26856686 Using gene expression from urine sediment to diagnose prostate cancer: development of a new multiplex mRNA urine test and validation of current biomarkers. 476 mRNA diagnostic biomarker EZH2 human tissue hepatocellular cancer H original research 26848027 Enhancer of zeste homolog 2 depletion arrests the proliferation of hepatoblastoma cells. 477 mRNA diagnostic biomarker HMGB1 human tissue lung cancer non-small cell lung cancer H original research 26840258 The effect of HMGB1 on the clinicopathological and prognostic features of non-small cell lung cancer. 478 mRNA diagnostic biomarker ECRG4 human tissue esophageal cancer L original research 26823803 Expression of esophageal carcinoma related gene 4 (ECRG4) and its clinical significance in prognosis of esophageal carcinoma. 479 mRNA diagnostic biomarker TTF1 human tissue hepatocellular cancer H original research 26821084 "Clinical and biological significance of transcription termination factor, RNA polymerase I in human liver hepatocellular carcinoma." 480 mRNA diagnostic biomarker "PCA3,TMPRSS2" human tissue prostate cancer H(PCA3) original research 26820133 Use of two gene panels for prostate cancer diagnosis and patient risk stratification. 481 mRNA diagnostic biomarker "WWTR1,CAMTA1" human uncertain mesothelioma pleural mesothelioma uncertain review 26811225 The 2015 World Health Organization Classification of Tumors of the Pleura: Advances since the 2004 Classification. 482 mRNA diagnostic biomarker RBP1 human tissue lung cancer non-small cell lung cancer H original research 26807202 High expression of cellular retinol binding protein-1 in lung adenocarcinoma is associated with poor prognosis. 483 mRNA diagnostic biomarker LMO2 human uncertain leukaemia H original research 26796495 LMO2 Is a Specific Marker of T-Lymphoblastic Leukemia/Lymphoma 484 mRNA diagnostic biomarker HOXA1 human tissue gastric cancer H original research 26791264 Elevated HOXA1 expression correlates with accelerated tumor cell proliferation and poor prognosis in gastric cancer partly via cyclin D1. 485 mRNA diagnostic biomarker ST3GAL1 human tissue bladder cancer L original research 26783462 "Development of Monoclonal Antibodies against CMP-N-Acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (ST3Gal-I) Recombinant Protein Expressed in E. coli." 486 mRNA diagnostic biomarker SOX9 dog tissue testicular cancer uncertain original research 26777558 "Immunohistochemical expression of SOX9 protein in immature, mature, and neoplastic canine Sertoli cells." 487 mRNA diagnostic biomarker "SF3B1,EIF1AX" human uncertain melanoma primary leptomeningeal melanocytic neoplasm uncertain original research 26769193 SF3B1 and EIF1AX mutations occur in primary leptomeningeal melanocytic neoplasms; yet another similarity to uveal melanomas. 488 mRNA diagnostic biomarker "TPO,MPPED2" human tissue thyroid cancer papillary thyroid carcinoma L original research 26756467 Identification of Genes Associated with Papillary Thyroid Carcinoma (PTC) for Diagnosis by Integrated Analysis. 489 mRNA diagnostic biomarker "BGH3,MMP9,PDIA3" human tissue oral cancer oral squamous cell carcinoma H original research 26745629 "Largescale Transcriptomics Analysis Suggests Over-Expression of BGH3, MMP9 and PDIA3 in Oral Squamous Cell Carcinoma." 490 mRNA diagnostic biomarker COL3A1 human "tissue,plasma" colorectal cancer H original research 26741506 Epithelial but not stromal expression of collagen alpha-1(III) is a diagnostic and prognostic indicator of colorectal carcinoma. 491 mRNA diagnostic biomarker EDIL3 human uncertain pancreatic cancer H original research 26735172 Overexpressed EDIL3 predicts poor prognosis and promotes anchorage-independent tumor growth in human pancreatic cancer. 492 mRNA diagnostic biomarker "STAT6,CD34,CD99,BCL2" human tissue fibromatose solitary fibrous cancer L(BCL2) original research 26722515 "Immunohistochemical detection of STAT6, CD34, CD99 and BCL-2 for diagnosing solitary fibrous tumors/hemangiopericytomas." 493 mRNA diagnostic biomarker CNTN1 human uncertain thyroid cancer H original research 26722434 Contactin 1 as a potential biomarker promotes cell proliferation and invasion in thyroid cancer. 494 mRNA diagnostic biomarker "HMOX1,RET,PML" human tissue leukaemia acute myelocytic leukemia "H(HMOX1,RET),L(PML)" original research 26722301 "HO-1, RET and PML as possible markers for risk stratification of acute myelocytic leukemia and prognostic evaluation." 495 mRNA diagnostic biomarker WT1 human tissue ovarian cancer H original research 26721227 Wilms tumor protein 1 (WT1)-- not only a diagnostic but also a prognostic marker in high-grade serous ovarian carcinoma. 496 mRNA diagnostic biomarker CHRNA7 human uncertain colorectal cancer H original research 26719016 CHRNA7 inhibits cell invasion and metastasis of LoVo human colorectal cancer cells through PI3K/Akt signaling. 497 mRNA diagnostic biomarker MYB human uncertain adenoid cystic cancer H original research 26711587 Differences in MYB expression and gene abnormalities further confirm that salivary cribriform basal cell tumors and adenoid cystic carcinoma are two distinct tumor entities. 498 mRNA diagnostic biomarker MYB human uncertain cystic cancer H original research 26705183 Diagnostic value of MYB protein expression in adenoid cystic carcinoma and status of MYB gene copy number. 499 mRNA diagnostic biomarker HSP90A human "tissue,serum" hepatocellular cancer H original research 26704341 Transcriptomic and Proteomic Investigation of HSP90A as a Potential Biomarker for HCC. 500 mRNA diagnostic biomarker ERBB3 human uncertain breast cancer uncertain review 26692764 "Aberrant Splicing of Estrogen Receptor, HER2, and CD44 Genes in Breast Cancer." 501 mRNA diagnostic biomarker TBLR1 human uncertain hepatocellular cancer H original research 26680504 Theranostical nanosystem-mediated identification of an oncogene and highly effective therapy in hepatocellular carcinoma. 502 mRNA diagnostic biomarker ANO1 human tissue extragastrointestinal stromal cancer uncertain original research 26678977 Is DOG1 Immunoreactivity Specific to Gastrointestinal Stromal Tumor? 503 mRNA diagnostic biomarker HNSCC human tissue head and neck cancer H original research 26666815 Effect of HPV on tumor expression levels of the most commonly used markers in HNSCC. 504 mRNA diagnostic biomarker ERCC2 human tissue head and neck cancer H original research 26659720 Increased expression of ERCC2 gene in head and neck cancer is associated with aggressive tumors: a systematic review and case-control study. 505 mRNA diagnostic biomarker HAO2 "rat,mice,nude mice" cell hepatocellular cancer L original research 26658681 The metabolic gene HAO2 is downregulated in hepatocellular carcinoma and predicts metastasis and poor survival. 506 mRNA diagnostic biomarker "ANXA1,ANXA10" human tissue "cholangio cancer,pancreatic cancer" pancreatic ductal adenocarcinoma H original research 26644413 Immunohistochemical Markers Distinguishing Cholangiocellular Carcinoma (CCC) from Pancreatic Ductal Adenocarcinoma (PDAC) Discovered by Proteomic Analysis of Microdissected Cells. 507 mRNA diagnostic biomarker ADAMTS19 human uncertain colorectal cancer H original research 26634009 Epigenetic inactivation of the extracellular matrix metallopeptidase ADAMTS19 gene and the metastatic spread in colorectal cancer. 508 mRNA diagnostic biomarker PTTG human tissue salivary cancer salivary gland cancer H original research 26622390 Overexpression of the pituitary tumor transforming gene upregulates metastasis in malignant neoplasms of the human salivary glands. 509 mRNA diagnostic biomarker NDRG2 human tissue astrocytoma L original research 26619843 Tumour Biol. 2016 May;37(5):6261-5. doi: 10.1007/s13277-015-4491-y. Epub 2015 Nov 30. 510 mRNA diagnostic biomarker "CDH13,SHP1" human tissue uterine cancer endometrial cancer H original research 26597461 Methylation of tumor suppressor gene CDH13 and SHP1 promoters and their epigenetic regulation by the UHRF1/PRMT5 complex in endometrial carcinoma. 511 mRNA diagnostic biomarker ERBB2 human tissue esophageal cancer gastroesophageal cancer H original research 26581548 Mass-spectrometry-based quantitation of Her2 in gastroesophageal tumor tissue: comparison to IHC and FISH. 512 mRNA diagnostic biomarker EFNA2 human "tissue,serum" prostate cancer H original research 26561474 Diagnostic and prognostic value of tissue and circulating levels of Ephrin-A2 in prostate cancer. 513 mRNA diagnostic biomarker DEL-1 human tissue lung cancer H original research 26545781 Del-1 overexpression potentiates lung cancer cell proliferation and invasion. 514 mRNA diagnostic biomarker "PARN,NOCT" human tissue lung cancer squamous cell lung cancer H original research 26541675 Poly(A)-specific ribonuclease and Nocturnin in squamous cell lung cancer: prognostic value and impact on gene expression. 515 mRNA diagnostic biomarker MMP9 human uncertain uncertain H original research 26525923 "MMP-9 in translation: from molecule to brain physiology, pathology, and therapy." 516 mRNA diagnostic biomarker FARP2 human uncertain gastrointestinal cancer H review 26524858 Alternative Splicing Detection as Biomarker Candidates for Cancer Diagnosis and Treatment with Establishment of Clinical Biobank in Chiba University. 517 mRNA diagnostic biomarker WT1 human blood leukaemia H original research 26520650 Clinical usefulness of WT1 mRNA expression in bone marrow detected by a new WT1 mRNA assay kit for monitoring acute myeloid leukemia: a comparison with expression of WT1 mRNA in peripheral blood. 518 mRNA diagnostic biomarker "ETV6,RUNX1,PAX5" human uncertain leukaemia uncertain original research 26520622 Preserved global histone H4 acetylation linked to ETV6-RUNX1 fusion and PAX5 deletions is associated with favorable outcome in pediatric B-cell progenitor acute lymphoblastic leukemia. 519 mRNA diagnostic biomarker "MAPK1,TRAF2" human tissue lung cancer H original research 26518718 Identification of gene markers in the development of smoking-induced lung cancer. 520 mRNA diagnostic biomarker "TM4SFl,SLC26A3,TIZ,BARDI,FXRI,SEPTIN9" human serum ovarian cancer uncertain original research 26513889 The construction of cDNA library and the screening of related antigen of ascitic tumor cells of ovarian cancer. 521 mRNA diagnostic biomarker "TERT,SKP2,NKX2-1" human blood lung cancer non-small cell lung cancer H original research 26505456 Combination of multiple gene markers to detect circulating tumor cells in the peripheral blood of patients with non-small cell lung cancer using real-time PCR. 522 mRNA diagnostic biomarker COL11A1 human tissue pancreatic cancer H original research 26504042 "Gene Expression of Col11A1 Is a Marker Not only for Pancreas Carcinoma But also for Adenocarcinoma of the Papilla of Vater, Discriminating Between Carcinoma and Chronic Pancreatitis." 523 mRNA diagnostic biomarker ECT2 human "tissue,serum" gastric cancer H original research 26497353 Clinical significance of ECT2 expression in tissue and serum of gastric cancer patients. 524 mRNA diagnostic biomarker EPCAM human uncertain uncertain H review 26487959 Ultrasensitive detection of DNA and protein markers in cancer cells. 525 mRNA diagnostic biomarker KLK10 human tissue esophageal cancer esophageal squamous cell cancer H original research 26479703 Upregulated KLK10 inhibits esophageal cancer proliferation and enhances cisplatin sensitivity in vitro. 526 mRNA diagnostic biomarker IMP3 human tissue renal cancer H original research 26478857 Increased Insulin mRNA Binding Protein-3 Expression Correlates with Vascular Enhancement of Renal Cell Carcinoma by Intravenous Contrast-CT and is Associated with Bone Metastasis. 527 mRNA diagnostic biomarker DTL human tissue gastric cancer H original research 26472028 Overexpression of denticleless E3 ubiquitin protein ligase homolog (DTL) is related to poor outcome in gastric carcinoma. 528 mRNA diagnostic biomarker ARMCX1 human tissue cervical cancer cervical squamous cell carcinoma H original research 26464700 ALEX1 may be a novel biomarker for human cervical squamous cell carcinoma. 529 mRNA diagnostic biomarker AHSG human "plasma,serum" hypopharyngeal cancer hypopharyngeal squamous cell carcinoma H original research 26464644 Proteomic identification of alpha-2-HS-glycoprotein as a plasma biomarker of hypopharyngeal squamous cell carcinoma. 530 mRNA diagnostic biomarker EGR human uncertain prostate cancer H original research 26452381 Current State of ERG as Biomarker in Prostatic Adenocarcinoma. 531 mRNA diagnostic biomarker SLC39A6 human uncertain epithelial cancer H original research 26444413 SLC39A6: a potential target for diagnosis and therapy of esophageal carcinoma. 532 mRNA diagnostic biomarker ARHGEF7 human serum head and neck cancer head and neck squamous cell cancer H original research 26435503 NFκB-p50 as a blood based protein marker for early diagnosis and prognosis of head and neck squamous cell carcinoma. 533 mRNA diagnostic biomarker CAMTA1 human tissue hemangioendothelioma H original research 26414223 Nuclear Expression of CAMTA1 Distinguishes Epithelioid Hemangioendothelioma From Histologic Mimics. 534 mRNA diagnostic biomarker JAK2 human uncertain myeloma myeloproliferative neoplasm uncertain review 26408371 Myeloproliferative neoplasms and the JAK/STAT signaling pathway: an overview. 535 mRNA diagnostic biomarker SPDYE6 human uncertain cervical cancer H original research 26396976 Transcriptomic analyses of genes differentially expressed by high-risk and low-risk human papilloma virus E6 oncoproteins. 536 mRNA diagnostic biomarker CDKN3 human uncertain cervical cancer H original research 26372210 CDKN3 mRNA as a Biomarker for Survival and Therapeutic Target in Cervical Cancer. 537 mRNA diagnostic biomarker "TTF1,FOXE1,PAX8" human tissue thyroid cancer L original research 26370671 Gene expression of thyroid-specific transcription factors may help diagnose thyroid lesions but are not determinants of tumor progression. 538 mRNA diagnostic biomarker BRAF human tissue colorectal cancer uncertain original research 26359417 Co-existence of BRAF V600E Gene Mutation in Tumor and Non-tumoral Surrounding Tissues in Colorectal Cancer. 539 mRNA diagnostic biomarker CEBPD human uncertain hepatocellular cancer L original research 26358750 HMDB and 5-AzadC Combination Reverses Tumor Suppressor CCAAT/Enhancer-Binding Protein Delta to Strengthen the Death of Liver Cancer Cells. 540 mRNA diagnostic biomarker "NUPR1,GRN" human uncertain hepatocellular cancer H original research 26350749 Mitochondrial defect-responsive gene signature in liver-cancer progression. 541 mRNA diagnostic biomarker GGCT human tissue uncertain H review 26339607 Gamma-Glutamylcyclotransferase: A Novel Target Molecule for Cancer Diagnosis and Treatment. 542 mRNA diagnostic biomarker SYCP2 human tissue oropharyngeal cancer uncertain original research 26334652 Deregulation of SYCP2 predicts early stage human papillomavirus-positive oropharyngeal carcinoma: A prospective whole transcriptome analysis. 543 mRNA diagnostic biomarker "COL1A1,PDGFB" human tissue cutaneous cancer dermatofibrosarcoma protuberan uncertain original research 26332510 A Novel Chromosomal Translocation Associated With COL1A2-PDGFB Gene Fusion in Dermatofibrosarcoma Protuberans: PDGF Expression as a New Diagnostic Tool. 544 mRNA diagnostic biomarker "EREG,PGR" human plasma breast cancer ductal breast carcinoma uncertain original research 26319120 Candidate early detection protein biomarkers for ER+/PR+ invasive ductal breast carcinoma identified using pre-clinical plasma from the WHI observational study. 545 mRNA diagnostic biomarker MMSP human "tissue,serum" nasopharyngeal cancer uncertain original research 26300994 Detection of nasopharyngeal carcinoma in Morocco (North Africa) using a multiplex methylation-specific PCR biomarker assay. 546 mRNA diagnostic biomarker "BRCA1,ERBB2,TTP53" human tissue breast cancer H original research 26299666 "Differential Gene Expression of BRCA1,ERBB2 and TP53 biomarkers between Human Breast Tissue and Peripheral Blood Samples of Breast Cancer." 547 mRNA diagnostic biomarker HPAF1C human uncertain lung cancer non-small cell lung cancer H review 26282204 Human RNA polymerase II associated factor 1 complex promotes tumorigenesis by activating c-MYC transcription in non-small cell lung cancer. 548 mRNA diagnostic biomarker RTK human tissue uncertain uncertain review 26276717 Integrated proteo-genomic approach for early diagnosis and prognosis of cancer. 549 mRNA diagnostic biomarker "MAGEA11,TCHH" human tissue oral cancer oral squamous cell carcinoma "H(MAGEA11),L(TCHH)" original research 26273018 Differential mRNA expression profiling of oral squamous cell carcinoma by high-throughput RNA sequencing. 550 mRNA diagnostic biomarker ANOS1 human uncertain gastric cancer H original research 26270236 Function and diagnostic value of Anosmin-1 in gastric cancer progression. 551 mRNA diagnostic biomarker LYPD3 human "tissue,serum" ovarian cancer uncertain original research 26252839 A genetic polymorphism (rs17251221) in the calcium-sensing receptor is associated with ovarian cancer susceptibility. 552 mRNA diagnostic biomarker "TP73,TP53,GADD45G,CHFR,THBS1,CEBPA" human tissue nasopharyngeal cancer nasal cancer "H(DNMT1,C-myc,CEBPA),L(p53,THBSI)" original research 26252527 "Promoter methylation, mRNA expression of goat tumor‑associated genes and mRNA expression of DNA methyltransferase in enzootic nasal tumors." 553 mRNA diagnostic biomarker USP2 human tissue bladder cancer L original research 26250800 Assess the expression of ubiquitin specific protease USP2a for bladder cancer diagnosis. 554 mRNA diagnostic biomarker ERBB2 human tissue urothelial cancer H original research 26240484 Clinical Significance of Substaging and HER2 Expression in Papillary Nonmuscle Invasive Urothelial Cancers of the Urinary Bladder. 555 mRNA diagnostic biomarker "PCNA,CCND1,NAT1,NAT2" human uncertain colorectal cancer "H(PCNA,CCND1),L(NAT1,NAT2)" original research 26239303 In-depth analysis of the critical genes and pathways in colorectal cancer. 556 mRNA diagnostic biomarker "EXO1,CENPF,ANLN,PBK,C15ORF42" human uncertain nasopharyngeal cancer "H(C15ORF42),L(EXO1,CENPF,ANLN,PBK)" original research 26238040 Functional analysis of the nasopharyngeal carcinoma primary tumor‑associated gene interaction network. 557 mRNA diagnostic biomarker "TMEM79,ACOXL" human tissue prostate cancer H original research 26237329 "Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer." 558 mRNA diagnostic biomarker BAP1 human uncertain mesothelioma L original research 26226841 "Loss of expression of BAP1 is a useful adjunct, which strongly supports the diagnosis of mesothelioma in effusion cytology." 559 mRNA diagnostic biomarker S100A7 human uncertain oral cancer squamous cell carcinoma of the oral cavity H original research 26225121 Mechanistic attributes of S100A7 (psoriasin) in resistance of anoikis resulting tumor progression in squamous cell carcinoma of the oral cavity. 560 mRNA diagnostic biomarker "ECT2,PSRC1" human uncertain pancreatic cancer H original research 26214778 Integrated regulatory network involving differently expressed genes and protein-protein interaction on pancreatic cancer. 561 mRNA diagnostic biomarker "TWIST1,ZEB2" human tissue oral cancer oral squamous cell cancer uncertain original research 26214683 Co-Expression of TWIST1 and ZEB2 in Oral Squamous Cell Carcinoma Is Associated with Poor Survival. 562 mRNA diagnostic biomarker "OCLN,CDKN2A,MGMT,MLH1,DAPK1" human uncertain oral cancer oral squamous cell cancer L(MGMT) original research 26213212 Identification of methylation markers for the prediction of nodal metastasis in oral and oropharyngeal squamous cell carcinoma. 563 mRNA diagnostic biomarker IL13RA1 human uncertain breast cancer H original research 26208975 Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasis. 564 mRNA diagnostic biomarker GRP78 human plasma brain tumor brain cancer glioblastoma multiforme H original research 26207187 Identification of the Transmembrane Glucose Regulated Protein 78 as a Biomarker for the Brain Cancer Glioblastoma Multiforme by Gene Expression and Proteomic Studies. 565 mRNA diagnostic biomarker "SFRP1,SLC5A8" human uncertain colorectal cancer "H(SLC5A8),L(SFRP1)" original research 26203307 DNA hypermethylation appears early and shows increased frequency with dysplasia in Lynch syndrome-associated colorectal adenomas and carcinomas. 566 mRNA diagnostic biomarker XB130 human tissue breast cancer ductal breast cancer H original research 26191231 Expression of XB130 in human ductal breast cancer. 567 mRNA diagnostic biomarker "GBM128,GBM131" human tissue glioma glioblastoma uncertain original research 26189784 Aptamer for imaging and therapeutic targeting of brain tumor glioblastoma. 568 mRNA diagnostic biomarker TP73 human tissue Wilms' tumor H original research 26184366 Evaluation of promoter hypomethylation and expression of p73 as a diagnostic and prognostic biomarker in Wilms' tumour. 569 mRNA diagnostic biomarker AQP1 human tissue osteosarcoma H original research 26176849 "RNAi-mediated silencing of AQP1 expression inhibited the proliferation, invasion and tumorigenesis of osteosarcoma cells." 570 mRNA diagnostic biomarker "RAB2A,PRDX1" human uncertain oral cancer oral squamous cell cancer H original research 26159854 Identification of RAB2A and PRDX1 as the potential biomarkers for oral squamous cell carcinoma using mass spectrometry-based comparative proteomic approach. 571 mRNA diagnostic biomarker WBP2NL human tissue breast cancer H original research 26157336 Elevated Expression of the Testis-specific Gene WBP2NL in Breast Cancer. 572 mRNA diagnostic biomarker RPS24 human uncertain colorectal cancer H review 26149657 RPS24 knockdown inhibits colorectal cancer cell migration and proliferation in vitro. 573 mRNA diagnostic biomarker BRG1 human tissue ovarian cancer ovarian small cell carcinoma L original research 26135561 "SMARCA4 (BRG1) loss of expression is a useful marker for the diagnosis of ovarian small cell carcinoma of the hypercalcemic type (ovarian rhabdoid tumor): a comprehensive analysis of 116 rare gynecologic tumors, 9 soft tissue tumors, and 9 melanomas." 574 mRNA diagnostic biomarker SIRT3 human tissue pancreatic cancer L original research 26121130 SIRT3 & SIRT7: Potential Novel Biomarkers for Determining Outcome in Pancreatic Cancer Patients. 575 mRNA diagnostic biomarker "GPX1,GPX3,GPX4" human uncertain renal cancer clear cell renal cell carcinomas L original research 26112936 Aberrant expression of selenium-containing glutathione peroxidases in clear cell renal cell carcinomas. 576 mRNA diagnostic biomarker TAF7L human tissue breast cancer H original research 26107214 Cancer/Testis OIP5 and TAF7L Genes are Up-Regulated in Breast Cancer. 577 mRNA diagnostic biomarker TMAO human uncertain colorectal cancer H original research 26100814 "A genome-wide systems analysis reveals strong link between colorectal cancer and trimethylamine N-oxide (TMAO), a gut microbial metabolite of dietary meat and fat." 578 mRNA diagnostic biomarker MEF2B human "tissue,plasma" lymphoma H original research 26089142 Pattern of MEF2B expression in lymphoid tissues and in malignant lymphomas. 579 mRNA diagnostic biomarker ATP5E human tissue thyroid cancer papillary thyroid cancer L original research 26079849 Molecular Analysis by Gene Expression of Mitochondrial ATPase Subunits in Papillary Thyroid Cancer: Is ATP5E Transcript a Possible Early Tumor Marker? 580 mRNA diagnostic biomarker "FOXP1,SPINK1" human tissue hepatocellular cancer H original research 26054682 FOXP1 and SPINK1 reflect the risk of cirrhosis progression to HCC with HBV infection. 581 mRNA diagnostic biomarker "DLAT,SPDYE7P,SPDYE6" human tissue cervical cancer L(E7) original research 26052817 Expressions of E2 and E7-HPV16 proteins in pre-malignant and malignant lesions of the uterine cervix. 582 mRNA diagnostic biomarker INI1 human uncertain cystic cancer L original research 26045850 Cystic synovial sarcoma of the pleura mimicking a cystic thymoma: a case report illustrating the role of decreased INI-1 expression in differential diagnosis. 583 mRNA diagnostic biomarker ABCB1 human "serum,cell" prostate cancer H original research 26027763 Serum exosomal P-glycoprotein is a potential marker to diagnose docetaxel resistance and select a taxoid for patients with prostate cancer. 584 mRNA diagnostic biomarker BAP1 human tissue mesothelioma L original research 26022455 BAP1 (BRCA1-associated protein 1) is a highly specific marker for differentiating mesothelioma from reactive mesothelial proliferations. 585 mRNA diagnostic biomarker NSE human serum lung cancer small cell lung cancer "H(LDH,CRP,CEA,NSE)" original research 25996920 A Highly Efficient Gene Expression Programming (GEP) Model for Auxiliary Diagnosis of Small Cell Lung Cancer. 586 mRNA diagnostic biomarker "CK18,KRT19" human "tissue,blood" nasopharyngeal cancer H original research 25989654 Detection of cytokeratin18 and cytokeratin19 gene expression in blood and tumor tissue of nasopharyngeal carcinoma patients by RT-PCR. 587 mRNA diagnostic biomarker "CD3Z,CD8A" human tissue colorectal cancer L original research 25970543 "Immune response gene expression in colorectal cancer carries distinct prognostic implications according to tissue, stage and site: a prospective retrospective translational study in the context of a hellenic cooperative oncology group randomised trial." 588 mRNA diagnostic biomarker "PAX7,SOX2" human tissue adenoid cystic cancer corticotroph pituitary adenoma L original research 25956343 Expression and clinical relevance of paired box protein 7 and sex determining region Y-box 2 in canine corticotroph pituitary adenomas. 589 mRNA diagnostic biomarker MACC1 human tissue colorectal cancer H original research 25953673 Metastasis-associated in colon cancer 1 is an independent prognostic biomarker for survival in Klatskin tumor patients. 590 mRNA diagnostic biomarker SPON2 human "tissue,plasma" colorectal cancer H original research 25945835 Upregulation of spondin-2 predicts poor survival of colorectal carcinoma patients. 591 mRNA diagnostic biomarker SPAG9 human tissue salivary cancer salivary gland cancer. H original research 25941602 Sperm associated antigen 9 (SPAG9) expression and humoral response in benign and malignant salivary gland tumors. 592 mRNA diagnostic biomarker MYCN human uncertain medulloblastoma H original research 25940061 Gorlin syndrome and desmoplastic medulloblastoma: Report of 3 cases with unfavorable clinical course and novel mutations. 593 mRNA diagnostic biomarker B4GALNT1 human "tissue,blood" retinoblastoma uncertain original research 25928893 Association of Cone-Rod Homeobox Transcription Factor Messenger RNA With Pediatric Metastatic Retinoblastoma. 594 mRNA diagnostic biomarker SIX2 human blood Wilms' tumor H original research 25921281 Assessment of promoter methylation and expression of SIX2 as a diagnostic and prognostic biomarker in Wilms' tumor. 595 mRNA diagnostic biomarker GPC3 human uncertain urothelial cancer H original research 25896897 Expression of Glypican 3 in low and high grade urothelial carcinomas. 596 mRNA diagnostic biomarker MYC human uncertain angiosarcoma H original research 25893585 Angiosarcoma and atypical vascular lesions of the breast: diagnostic and prognostic role of MYC gene amplification and protein expression. 597 mRNA diagnostic biomarker "ALDH1A2,ADH1B,HBB,ABCA8,ALDH1A2,ABCA8" human uncertain ovarian cancer "H(HBB),L(ALDH1A2,ADH1B,ABCA8,ALDH1A2,ABCA8)" original research 25891226 Discovery of microarray-identified genes associated with ovarian cancer progression. 598 mRNA diagnostic biomarker PRISM human tissue prostate cancer uncertain original research 25889691 Analytical platform evaluation for quantification of ERG in prostate cancer using protein and mRNA detection methods. 599 mRNA diagnostic biomarker CKS2 human uncertain bladder cancer H original research 25889321 Gene expression patterns combined with network analysis identify hub genes associated with bladder cancer. 600 mRNA diagnostic biomarker PDXP human uncertain uncertain H original research 25885340 Cancers of unknown primary origin (CUP) are characterized by chromosomal instability (CIN) compared to metastasis of know origin. 601 mRNA diagnostic biomarker PTEN human tissue lung cancer L original research 25884169 Lung neuroendocrine tumors: correlation of ubiquitinylation and sumoylation with nucleo-cytosolic partitioning of PTEN. 602 mRNA diagnostic biomarker ULK1 human serum prostate cancer uncertain original research 25881865 Expression Profile of Autophagy-related Markers in Localized Prostate Cancer: Correlation With Biochemical Recurrence After Radical Prostatectomy. 603 mRNA diagnostic biomarker FOXL2 human tissue ovarian cancer H original research 25871347 Identification and Validation of Differential Phosphorylation Sites of the Nuclear FOXL2 Protein as Potential Novel Biomarkers for Adult-Type Granulosa Cell Tumors. 604 mRNA diagnostic biomarker BST2 human tissue breast cancer H original research 25860442 Bone marrow stromal antigen 2 (BST-2) DNA is demethylated in breast tumors and breast cancer cells. 605 mRNA diagnostic biomarker SV2A human tissue glioma L original research 25845910 Analysis of gene expression profiles associated with glioma progression. 606 mRNA diagnostic biomarker "EPS8,WT1,MDR1" human tissue leukaemia H original research 25843487 Overexpression of EPS8 is associated with poor prognosis in patients with acute lymphoblastic leukemia. 607 mRNA diagnostic biomarker SDHB human uncertain renal cancer clear cell renal cell carcinoma L original research 25827535 Succinate dehydrogenase B: a new prognostic biomarker in clear cell renal cell carcinoma. 608 mRNA diagnostic biomarker ATAD2 human tissue cervical cancer H original research 25813398 "Oncogene ATAD2 promotes cell proliferation, invasion and migration in cervical cancer." 609 mRNA diagnostic biomarker TOX human uncertain mycosis fungoide H original research 25811617 TOX acts an oncological role in mycosis fungoides. 610 mRNA diagnostic biomarker ATP1A3 human "tissue,serum" uncertain H original research 25809299 Neuronal Na+/K+ ATPase is an autoantibody target in paraneoplastic neurologic syndrome. 611 mRNA diagnostic biomarker RASSF1A human tissue ovarian cancer epithelial ovarian cancer L original research 25807435 Eur Rev Med Pharmacol Sci. 2015;19(5):813-7. 612 mRNA diagnostic biomarker BMP2 human tissue renal cancer L original research 25797254 Inactivation of bone morphogenetic protein 2 may predict clinical outcome and poor overall survival for renal cell carcinoma through epigenetic pathways. 613 mRNA diagnostic biomarker EPHB6 human tissue prostate cancer L original research 25789021 Reduced expression of erythropoietin-producing hepatocyte B6 receptor tyrosine kinase in prostate cancer. 614 mRNA diagnostic biomarker BRAF human uncertain glioma uncertain review 25785246 "Current Understanding of BRAF Alterations in Diagnosis, Prognosis, and Therapeutic Targeting in Pediatric Low-Grade Gliomas." 615 mRNA diagnostic biomarker PSPH chicken tissue ovarian cancer H original research 25776463 Estrogen regulation of phosphoserine phosphatase during regression and recrudescence of female reproductive organs. 616 mRNA diagnostic biomarker "GSTM1,GSTT1" human uncertain breast cancer uncertain original research 25774687 The identification of specific methylation patterns across different cancers. 617 mRNA diagnostic biomarker "ERBB2,NUE" human tissue breast cancer H original research 25763209 Overexpression of HER2/neu as a Prognostic Value in Iranian Women With Early Stage Breast Cancer; A Single Institute Study. 618 mRNA diagnostic biomarker SFRP1 human tissue bladder cancer L original research 25732201 Functional analyses and prognostic significance of SFRP1 expression in bladder cancer. 619 mRNA diagnostic biomarker TSPAN8 human tissue gastric cancer H original research 25711980 "TSPAN8, identified by Escherichia coli ampicillin secretion trap, is associated with cell growth and invasion in gastric cancer." 620 mRNA diagnostic biomarker "EML4,ALK" human uncertain lung cancer non-small cell lung cancer uncertain original research 25708242 Anaplastic lymphoma kinase translocation is correlated with anaplastic lymphoma kinase expression and mutually exclusive with epidermal growth factor receptor mutation in Taiwanese non-small cell lung cancer. 621 mRNA diagnostic biomarker SATB1 human tissue bladder cancer H original research 25706386 SATB1 overexpression regulates the development and progression in bladder cancer through EMT. 622 mRNA diagnostic biomarker "TPM3,ERP29,CAMP,HSPA8" human tissue colorectal cancer H original research 25699276 Biomed Res Int. 2015;2015:365068. doi: 10.1155/2015/365068. Epub 2015 Jan 28. 623 mRNA diagnostic biomarker "MDM2,CDK4" human uncertain osteosarcoma L original research 25680902 MDM2 and CDK4 expression in periosteal osteosarcoma. 624 mRNA diagnostic biomarker "MDM2,ATRX,WT1,CKITIHC" human uncertain lipoblastoma dedifferentiated liposarcoma uncertain review 25675083 Immunohistochemistry as a surrogate for molecular testing: a review. 625 mRNA diagnostic biomarker "ERBB2,NEU,MKI67" human uncertain breast cancer "H(ERBB2,NEU)" original research 25671359 Hopes and pitfalls of the molecular classification of breast cancer. 626 mRNA diagnostic biomarker TERT human tissue bladder cancer uncertain original research 25657201 TERT promoter mutations and TERT mRNA but not FGFR3 mutations are urinary biomarkers in Han Chinese patients with urothelial bladder cancer. 627 mRNA diagnostic biomarker WISP1 human uncertain lung cancer uncertain original research 25656821 Association of Wnt-Inducible Signaling Pathway Protein 1 Genetic Polymorphisms With Lung Cancer Susceptibility and Platinum-Based Chemotherapy Response. 628 mRNA diagnostic biomarker NPTX1 human tissue lung cancer L original research 25646694 NPTX1 is a novel epigenetic regulation gene and associated with prognosis in lung cancer. 629 mRNA diagnostic biomarker HSP105 human uncertain breast cancer H original research 25645927 HSP105 recruits protein phosphatase 2A to dephosphorylate β-catenin. 630 mRNA diagnostic biomarker PTTG1 human tissue gastric cancer H original research 25627474 Pituitary tumor-transforming gene-1 serves as an independent prognostic biomarker for gastric cancer. 631 mRNA diagnostic biomarker GPC3 mice uncertain hepatocellular cancer L original research 25625609 Enhanced specific antitumor immunity of dendritic cells transduced with the glypican 3 gene and co-cultured with cytokine-induced killer cells against hepatocellular carcinoma cells. 632 mRNA diagnostic biomarker "TP53,BCL2,MKI67" human tissue ovarian cancer "H(TP53,MKI67),L(BCL2)" original research 25610057 "P53, bcl-2, ki-67 li (labeling index) status in benign, proliferative, and malignant ovarian surface epithelial neoplasms." 633 mRNA diagnostic biomarker CHP2 human uncertain leukaemia H original research 25606416 CHP2 gene expression and quantitation in Egyptian patients with acute leukemia. 634 mRNA diagnostic biomarker "NNMT,NR3C1" human tissue renal cancer clear cell renal cell carcinoma H original research 25594006 Alteredmetabolicpathwaysinclearcellrenalcellcarcinoma:Ameta-analysisandvalidationstudyfocusedonthederegulatedgenesandtheirassociatednetworks. 635 mRNA diagnostic biomarker RBMS3 human tissue lung cancer lung squamous cell carcinoma L original research 25588924 RBMS3 is a tumor suppressor gene that acts as a favorable prognostic marker in lung squamous cell carcinoma. 636 mRNA diagnostic biomarker "UBD,SAA1" human tissue cervical cancer cervical squamous cell carcinoma H original research 25586346 Transcriptome profiling of the cancer and adjacent nontumor tissues from cervical squamous cell carcinoma patients by RNA sequencing. 637 mRNA diagnostic biomarker FAM83B human tissue lung cancer lung squamous cell carcinoma H original research 25586059 FAM83B is a novel biomarker for diagnosis and prognosis of lung squamous cell carcinoma. 638 mRNA diagnostic biomarker SPP1 human uncertain prostate cancer H original research 25577832 The highly expressed secreted phosphoprotein 1 gene in prostate cancer metastasis: a microarray-based bioinformatic analysis. 639 mRNA diagnostic biomarker RERE human uncertain hepatocellular cancer uncertain original research 25577247 Arginase-1 is a more sensitive marker than HepPar-1 and AFP in differential diagnosis of hepatocellular carcinoma from nonhepatocellular carcinoma. 640 mRNA diagnostic biomarker "LHDC7B,SYCP2" human tissue cervical cancer cervical squamous cell carcinoma uncertain original research 25565867 The landscape of alternative splicing in cervical squamous cell carcinoma. 641 mRNA diagnostic biomarker ANGPTL2 human "tissue,serum" esophageal cancer H original research 25564164 Angiopoietin-Like Protein 2 Acts as a Novel Biomarker for Diagnosis and Prognosis in Patients with Esophageal Cancer. 642 mRNA diagnostic biomarker HMB45 human tissue renal cancer H original research 25562596 Renal cell carcinoma with t(6:11) (p21;q12). A case report highlighting distinctive immunohistologic features of this rare tumor. 643 mRNA diagnostic biomarker "STUM,CTTNBP2,SUGCT,SYNDIG1,PRELID3B,FAM19A5" human "tissue,plasma,serum" pancreatic cancer "H(C1orf 94,C7orf10,FAM19A5,KIAA 1217),L(C7orf8,C20orf45)" original research 25560640 Phenome-genome association studies of pancreatic cancer: new targets for therapy and diagnosis. 644 mRNA diagnostic biomarker GPC4 human tissue hepatocellular cancer L original research 25553423 Down-regulating glypican-3 expression: molecular-targeted therapy for hepatocellular carcinoma. 645 mRNA diagnostic biomarker CLCA2 human uncertain lung cancer non-small cell lung cancer H original research 25548429 CLCA2 as a novel immunohistochemical marker for differential diagnosis of squamous cell carcinoma from adenocarcinoma of the lung. 646 mRNA diagnostic biomarker MACC1 human plasma lung cancer non-small cell lung cancer H original research 25544672 Circulating MACC1 as a novel diagnostic and prognostic biomarker for non small cell lung cancer. 647 mRNA diagnostic biomarker KRT13 human uncertain oral cancer oral squamous cell carcinoma L original research 25527207 Epigenetic alterations of the keratin 13 gene in oral squamous cell carcinoma. 648 mRNA diagnostic biomarker RUNX3 human tissue breast cancer H original research 25525332 Clinicopathological significance and potential drug target of RUNX3 in breast cancer. 649 mRNA diagnostic biomarker MARVELD1 human tissue lung cancer L original research 25520033 Biological and clinical significance of epigenetic silencing of MARVELD1 gene in lung cancer. 650 mRNA diagnostic biomarker SFTPA2 human tissue lung cancer L original research 25514367 DNA methylation profile and expression of surfactant protein A2 gene in lung cancer. 651 mRNA diagnostic biomarker CCL18 human "tissue,serum" pancreatic cancer pancreatic ductal adenocarcinoma H original research 25502147 "CCL18 promotes epithelial-mesenchymal transition, invasion and migration of pancreatic cancer cells in pancreatic ductal adenocarcinoma." 652 mRNA diagnostic biomarker FABP7 human tissue adenoid cystic cancer H original research 25500088 Fatty Acid binding protein 7 is a molecular marker in adenoid cystic carcinoma of the salivary glands: implications for clinical significance. 653 mRNA diagnostic biomarker TES human tissue glioma glioblastoma L original research 25498217 Downregulation of TES by hypermethylation in glioblastoma reduces cell apoptosis and predicts poor clinical outcome. 654 mRNA diagnostic biomarker HJURP human uncertain breast cancer H original research 25497280 The histone chaperone HJURP is a new independent prognostic marker for luminal A breast carcinoma. 655 mRNA diagnostic biomarker CCL2 human "tissue,serum" prostate cancer H original research 25483747 CCL2 Chemokine as a Potential Biomarker for Prostate Cancer: A Pilot Study. 656 mRNA diagnostic biomarker PTGDS chicken uncertain ovarian cancer H original research 25475724 Prostaglandin D₂ synthase related to estrogen in the female reproductive tract. 657 mRNA diagnostic biomarker ALCAM human tissue salivary cancer salivary gland cancer H(CD166) original research 25472586 Clinical implication of CD166 expression in salivary gland tumor. 658 mRNA diagnostic biomarker UT-B human tissue urothelial cancer urothelial carcinoma of the bladder L original research 25445116 Clinical significance of the reduction of UT-B expression in urothelial carcinoma of the bladder. 659 mRNA diagnostic biomarker PAX5 human uncertain leukaemia uncertain review 25428382 The role of Pax5 in leukemia: diagnosis and prognosis significance. 660 mRNA diagnostic biomarker HHIP human uncertain glioma L original research 25416442 Epigenetic regulation of human hedgehog interacting protein in glioma cell lines and primary tumor samples. 661 mRNA diagnostic biomarker CXCL8 human "tissue,serum" colon cancer H review 25408728 Expression of interleukine-8 as an independent prognostic factor for sporadic colon cancer dissemination. 662 mRNA diagnostic biomarker SMAD4 human tissue colorectal cancer L original research 25400417 Deletion and down-regulation of SMAD4 gene in colorectal cancers in a Chinese population. 663 mRNA diagnostic biomarker ASPH human tissue hepatocellular cancer H(HAAH) original research 25394783 Evaluation of HAAH/humbug quantitative detection in the diagnosis of hepatocellular carcinoma. 664 mRNA diagnostic biomarker CDH13 human tissue lung cancer non-small cell lung cancer H original research 25382980 Prognostic significance of CDH13 hypermethylation and mRNA in NSCLC. 665 mRNA diagnostic biomarker MC1R human uncertain melanoma uncertain original research 25382380 Inherited variation at MC1R and ASIP and association with melanoma-specific survival. 666 mRNA diagnostic biomarker ZBTB16 human tissue hepatocellular cancer L original research 25369784 Downregulation of PLZF in human hepatocellular carcinoma and its clinical significance. 667 mRNA diagnostic biomarker CCNB3 human tissue sarcoma uncertain original research 25360585 BCOR-CCNB3 fusions are frequent in undifferentiated sarcomas of male children. 668 mRNA diagnostic biomarker PSD human tissue gastric cancer L original research 25355626 The Pleckstrin and Sec7 domain-containing gene as a novel epigenetic modification marker in human gastric cancer and its clinical significance. 669 mRNA diagnostic biomarker HMGA human tissue lung cancer non-small cell lung cancer H original research 25344216 Elevated expression of HMGA1 correlates with the malignant status and prognosis of non-small cell lung cancer. 670 mRNA diagnostic biomarker DUSP6 human tissue lung cancer non-small cell lung cancer L original research 25344212 Prognostic value of dual-specificity phosphatase 6 expression in non-small cell lung cancer. 671 mRNA diagnostic biomarker RSF1 human tissue breast cancer H original research 25337201 "Overexpression of Rsf-1 correlates with pathological type, p53 status and survival in primary breast cancer." 672 mRNA diagnostic biomarker RUNX3 human tissue ovarian cancer L original research 25333219 RUNX3 is inactivated by promoter hypermethylation in malignant transformation of ovarian endometriosis. 673 mRNA diagnostic biomarker "VAMP2,MYT1L,GPRASP1,TSPYL2,CHGA,MAPRE3,SNAP91,NKX2-2,ERBB2,HER2,GALE,PRSS8,PYCR1" human uncertain lung cancer "small-cell lung cancer, carcinoid, metastasis" H(ERBB2) original research 25325012 "Hidden treasures in ""ancient"" microarrays: gene-expression portrays biology and potential resistance pathways of major lung cancer subtypes and normal tissue." 674 mRNA diagnostic biomarker HOXB9 human uncertain lung cancer non-small cell lung cancer H original research 25324169 High expression of transcriptional factor HoxB9 predicts poor prognosis in patients with lung adenocarcinoma. 675 mRNA diagnostic biomarker "EGFR,CCND1" human tissue melanoma nodular melanoma H original research 25304234 EGFR and cyclin D1 in nodular melanoma: correlation with pathohistological parameters and overall survival. 676 mRNA diagnostic biomarker FGL2 human tissue lymphoma H original research 25303152 "Increased activity of cell membrane-associated prothrombinase, fibrinogen-like protein 2, in peripheral blood mononuclear cells of B-cell lymphoma patients." 677 mRNA diagnostic biomarker SLCO1A2 human tissue lung cancer small cell lung cancer H original research 25301452 Specific expression of OATPs in primary small cell lung cancer (SCLC) cells as novel biomarkers for diagnosis and therapy. 678 mRNA diagnostic biomarker GPC3 human tissue uncertain H review 25299314 Discovery and diagnostic value of a novel oncofetal protein: glypican 3. 679 mRNA diagnostic biomarker XAGE human "tissue,blood" hepatocellular cancer H original research 25279215 XAGE-1b expression is associated with the diagnosis and early recurrence of hepatocellular carcinoma. 680 mRNA diagnostic biomarker DMRs human tissue pancreatic cancer uncertain original research 25276247 High-frequency aberrantly methylated targets in pancreatic adenocarcinoma identified via global DNA methylation analysis using methylCap-seq. 681 mRNA diagnostic biomarker MCMBP human tissue colorectal cancer H original research 25246271 Deregulation of the replisome factor MCMBP prompts oncogenesis in colorectal carcinomas through chromosomal instability. 682 mRNA diagnostic biomarker "OCT3,POU5F1,SRY,SOX2,SOX17" human uncertain germ cell cancer uncertain review 25240975 Gonadal maldevelopment as risk factor for germ cell cancer: towards a clinical decision model. 683 mRNA diagnostic biomarker HLA-G human tissue uncertain L review 25237627 "Impact of HLA-G analysis in prevention, diagnosis and treatment of pathological conditions." 684 mRNA diagnostic biomarker RRM2 human tissue breast cancer ER-negative breast cancer H original research 25213022 Prognostic and therapeutic significance of ribonucleotide reductase small subunit M2 in estrogen-negative breast cancers. 685 mRNA diagnostic biomarker HSPD1 human tissue gastric cancer H original research 25207654 Heat shock protein 60 overexpression is associated with the progression and prognosis in gastric cancer. 686 mRNA diagnostic biomarker MCC human uncertain myeloma H original research 25200342 Mutated in colorectal cancer (MCC) is a novel oncogene in B lymphocytes. 687 mRNA diagnostic biomarker "COL1A2,COL5A2,MMP1,MMP2,MMP3,MMP14,TGF,RUNX2" human uncertain osteosarcoma "H(COL1A2,COL5A2)" original research 25199469 Screening of diagnostic markers for osteosarcoma. 688 mRNA diagnostic biomarker "KRAS,GNAS,RNF43,CTNNB1" human uncertain pancreatic cancer uncertain review 25191518 Utilization of ancillary studies in the cytologic diagnosis of biliary and pancreatic lesions: The Papanicolaou Society of Cytopathology Guidelines. 689 mRNA diagnostic biomarker "NAPSA,NKX2,NAPSA" human tissue lung cancer H original research 25169055 The lung-specific proteome defined by integration of transcriptomics and antibody-based profiling. 690 mRNA diagnostic biomarker ANGPTL4 human tissue hepatocellular cancer L original research 25148701 Clinical relevance and therapeutic potential of angiopoietin-like protein 4 in hepatocellular carcinoma. 691 mRNA diagnostic biomarker S100A8 human serum gastric cancer uncertain original research 25141238 Proteomic characterization of Helicobacter pylori CagA antigen recognized by child serum antibodies and its epitope mapping by peptide array. 692 mRNA diagnostic biomarker "MUC1,ERBB2" human serum breast cancer H original research 25128064 Designing a recombinant chimeric construct contain MUC1 and HER2 extracellular domain for prediagnostic breast cancer. 693 mRNA diagnostic biomarker CDH1 human tissue breast cancer L original research 25124632 Loss of expression and aberrant methylation of the CDH1 (E-cadherin) gene in breast cancer patients from Kashmir. 694 mRNA diagnostic biomarker GPM6B human uncertain gynecological cancer H original research 25113253 Vascular marker expression during the development of various types of gynaecological malignancy. 695 mRNA diagnostic biomarker ANP32B human serum pancreatic cancer H original research 25110120 "Soluble a‑proliferation‑inducing ligand (sAPRIL), a novel serum biomarker predicting the recurrence and metastasis of pancreatic adenocarcinoma after surgery." 696 mRNA diagnostic biomarker TP53 human serum prostate cancer L original research 25109857 A novel method for the sensitive detection of mutant proteins using a covalent-bonding tube-based proximity ligation assay. 697 mRNA diagnostic biomarker SPP1 human serum hepatocellular cancer H(OPN) original research 25109745 Serum anti-osteopontin autoantibody as a novel diagnostic and prognostic biomarker in patients with hepatocellular carcinoma. 698 mRNA diagnostic biomarker "RPS6KB1,RPS6KB1" human plasma uncertain uncertain review 25100792 p70 Ribosomal protein S6 kinase (Rps6kb1): an update. 699 mRNA diagnostic biomarker ITIH5 human tissue colon cancer L original research 25093535 Epigenetic inactivation of the novel candidate tumor suppressor gene ITIH5 in colon cancer predicts unfavorable overall survival in the CpG island methylator phenotype. 700 mRNA diagnostic biomarker APPL1 human tissue prostate cancer H review 25080433 Altered endosome biogenesis in prostate cancer has biomarker potential. 701 mRNA diagnostic biomarker SP1 human uncertain prostate cancer uncertain original research 25080090 Integrative analysis reveals disease-associated genes and biomarkers for prostate cancer progression. 702 mRNA diagnostic biomarker BMP3 human tissue cholangio cancer H original research 25077038 Methylated Bone Morphogenetic Protein 3 (BMP3) Gene: Evaluation of Tumor Suppressor Function and Biomarker Potential in Biliary Cancer. 703 mRNA diagnostic biomarker "ROS1,BRAF,HER2" human uncertain lung cancer non-small cell lung cancer uncertain original research 25058391 Screening of ROS1 rearrangements in lung adenocarcinoma by immunohistochemistry and comparison with ALK rearrangements. 704 mRNA diagnostic biomarker YY1 human tissue prostate cancer H review 25053986 Role of YY1 in the pathogenesis of prostate cancer and correlation with bioinformatic data sets of gene expression. 705 mRNA diagnostic biomarker SFRP2 human "stool,tissue" colorectal cancer uncertain original research 25053594 Variation risks of SFRP2 hypermethylation between precancerous disease and colorectal cancer. 706 mRNA diagnostic biomarker SLC22A3 human uncertain uncertain uncertain review 25050175 Clinical significance of epithelial-mesenchymal transition. 707 mRNA diagnostic biomarker NPPB human tissue ovarian cancer epithelial ovarian cancer H original research 25047817 NPPB is a novel candidate biomarker expressed by cancer-associated fibroblasts in epithelial ovarian cancer. 708 mRNA diagnostic biomarker KCTD11 human uncertain prostate cancer L original research 25045667 KCTD11 tumor suppressor gene expression is reduced in prostate adenocarcinoma. 709 mRNA diagnostic biomarker BCL6 human tissue glioma glioblastoma uncertain original research 25038272 Translocation of the proto-oncogene Bcl-6 in human glioblastoma multiforme. 710 mRNA diagnostic biomarker SRC human tissue leiomyosarcoma H original research 25028927 Gene expression profiling in leiomyosarcomas and undifferentiated pleomorphic sarcomas: SRC as a new diagnostic marker. 711 mRNA diagnostic biomarker "ERBB2,ERBB3" human tissue breast cancer metastatic breast cancer H original research 25017122 Co-overexpression of HER2/HER3 is a predictor of impaired survival in breast cancer patients. 712 mRNA diagnostic biomarker STAT5AB human tissue hepatocellular cancer L original research 25013898 Reliable quantification of protein expression and cellular localization in histological sections. 713 mRNA diagnostic biomarker "AXIN2,TNIP1" human blood prostate cancer uncertain original research 25013500 Significant association between the Axin2 rs2240308 single nucleotide polymorphism and the incidence of prostate cancer. 714 mRNA diagnostic biomarker SMARCB1 human tissue sinus cancer L original research 25007146 SMARCB1 (INI-1)-deficient carcinomas of the sinonasal tract. 715 mRNA diagnostic biomarker WT1 human tissue fibromatose "young-type fibromatose,infantile fibrosarcoma" H original research 25005570 Cytoplasmic expression of Wilms tumor transcription factor-1 (WT1): a useful immunomarker for young-type fibromatoses and infantile fibrosarcoma. 716 mRNA diagnostic biomarker MAPK human uncertain breast cancer H original research 24993294 Diet and lifestyle factors interact with MAPK genes to influence survival: the Breast Cancer Health Disparities Study. 717 mRNA diagnostic biomarker MAGE human "tissue,serum" glioma H original research 24966945 High expression and frequently humoral immune response of melanoma-associated antigen D4 in glioma. 718 mRNA diagnostic biomarker HERV human blood breast cancer H original research 24964007 Expression of human endogenous retrovirus env genes in the blood of breast cancer patients. 719 mRNA diagnostic biomarker "HOXC6,AMACR,PCA3" human tissue prostate cancer H(PCA3) original research 24937670 DNA methylation status is more reliable than gene expression at detecting cancer in prostate biopsy. 720 mRNA diagnostic biomarker PINX1 human tissue prostate cancer L original research 24936151 Reduced expression of PinX1 correlates to progressive features in patients with prostate cancer. 721 mRNA diagnostic biomarker FHIT human tissue lung cancer non-small cell lung cancer H original research 24935385 "Assessment of the prognostic value of methylation status and expression levels of FHIT, GSTP1 and p16 in non-small cell lung cancer in Egyptian patients." 722 mRNA diagnostic biomarker "PCA3,EGR" human uncertain prostate cancer H review 24928864 New concepts concerning prostate cancer screening. 723 mRNA diagnostic biomarker "EREG,PGR,ERBB2" human tissue breast cancer triple-negative breast cancer H original research 24928852 Chemogenetic evaluation of the mitotic kinesin CENP-E reveals a critical role in triple-negative breast cancer. 724 mRNA diagnostic biomarker AFP human "tissue,serum" hepatocellular cancer H original research 24927126 Development of a highly sensitive glycan microarray for quantifying AFP-L3 for early prediction of hepatitis B virus-related hepatocellular carcinoma. 725 mRNA diagnostic biomarker PTPRO human "tissue,plasma" breast cancer L original research 24919593 Aberrant PTPRO methylation in tumor tissues as a potential biomarker that predicts clinical outcomes in breast cancer patients. 726 mRNA diagnostic biomarker YY1 human tissue pancreatic cancer pancreatic ductal adenocarcinoma L original research 24884523 Yin Yang-1 suppresses invasion and metastasis of pancreatic ductal adenocarcinoma by downregulating MMP10 in a MUC4/ErbB2/p38/MEF2C-dependent mechanism. 727 mRNA diagnostic biomarker "CA4,CRYAB" human tissue thyroid cancer "H(CRYAB),L(CA4)" original research 24880201 Carbonic anhydrase 4 and crystallin α-B immunoreactivity may distinguish benign from malignant thyroid nodules in patients with indeterminate thyroid cytology. 728 mRNA diagnostic biomarker TRPV2 human tissue esophageal cancer esophageal squamous cell cancer H original research 24878697 Overexpression of transient receptor potential vanilloid 2 is associated with poor prognosis in patients with esophageal squamous cell carcinoma. 729 mRNA diagnostic biomarker SFRP2 human "stool ,tissue" colorectal cancer uncertain original research 24876755 Detection of promoter hypermethylation of Wnt antagonist genes in fecal samples for diagnosis of early colorectal cancer. 730 mRNA diagnostic biomarker JTB human uncertain renal cancer clear cell renal cell carcinoma H(PAR-3) original research 24856572 Cytoplasmic PAR-3 protein expression is associated with adverse prognostic factors in clear cell renal cell carcinoma and independently impacts survival. 731 mRNA diagnostic biomarker PTGR1 rat tissue hepatocellular cancer H original research 24853774 Increased expression of prostaglandin reductase 1 in hepatocellular carcinomas from clinical cases and experimental tumors in rats. 732 mRNA diagnostic biomarker M2PK human stool colorectal cancer H review 24852854 KRAS mutations and M2PK upregulation in stool samples from individuals with positive fecal occult blood tests screened for colorectal cancer. 733 mRNA diagnostic biomarker NDRG2 human tissue glioma L original research 24847385 Glioma Malignancy-Dependent NDRG2 Gene Methylation and Downregulation Correlates with Poor Patient Outcome. 734 mRNA diagnostic biomarker "RUNX2,CDC5L,MDM2,RECQL4,CDK4" human uncertain osteosarcoma "H(RUNX2,RECQL4),L(CDK4,MDM2)" original research 24835790 "Digital expression profiling identifies RUNX2, CDC5L, MDM2, RECQL4, and CDK4 as potential predictive biomarkers for neo-adjuvant chemotherapy response in paediatric osteosarcoma." 735 mRNA diagnostic biomarker ST13 human tissue glioma H(HSP70 ) original research 24833463 Reliability of HSP70 (HSPA) expression as a prognostic marker in glioma. 736 mRNA diagnostic biomarker ACPP chicken tissue ovarian cancer H original research 24829029 Avian prostatic acid phosphatase: estrogen regulation in the oviduct and epithelial cell-derived ovarian carcinomas. 737 mRNA diagnostic biomarker "PIK3C3,PIM3" human uncertain uncertain H original research 24818135 Gene expression correlation for cancer diagnosis: a pilot study. 738 mRNA diagnostic biomarker SKIP human tissue bladder cancer H original research 24817966 SKIP expression is correlated with clinical prognosis in patients with bladder cancer. 739 mRNA diagnostic biomarker HGF human tissue tonsillar cancer tonsillar squamous cell cancer L original research 24810547 Frequent hepatocyte growth factor overexpression and low frequency of c-Met gene amplification in human papillomavirus-negative tonsillar squamous cell carcinoma and their prognostic significances. 740 mRNA diagnostic biomarker CAPG human uncertain ovarian cancer H original research 24804218 Macrophage capping protein CapG is a putative oncogene involved in migration and invasiveness in ovarian carcinoma. 741 mRNA diagnostic biomarker "RB1,CDK4,CHMP2B,HSP90,KAT5" human uncertain lipoblastoma "myxofibrosarcoma, myxoid liposarcoma" "H(HSP90,Cpla2g4a),L(RB1)" original research 24788530 "Immunohistochemical analysis of expressions of RB1, CDK4, HSP90, cPLA2G4A, and CHMP2B is helpful in distinction between myxofibrosarcoma and myxoid liposarcoma." 742 mRNA diagnostic biomarker SPINK5 human uncertain neuroendocrine tumor L original research 24782827 Alternative polyadenylation of tumor suppressor genes in small intestinal neuroendocrine tumors. 743 mRNA diagnostic biomarker GEC human uncertain neuroblastoma L original research 24780044 An independent study of a gene expression classifier (Afirma) in the evaluation of cytologically indeterminate thyroid nodules. 744 mRNA diagnostic biomarker GCF2 human serum hepatocellular cancer L original research 24761896 Knockdown of GCF2/LRRFIP1 by RNAi causes cell growth inhibition and increased apoptosis in human hepatoma HepG2 cells. 745 mRNA diagnostic biomarker HLA-DOB human uncertain lung cancer non-small cell lung cancer uncertain original research 24755914 Inflammation-related genetic variations and survival in patients with advanced non-small cell lung cancer receiving first-line chemotherapy. 746 mRNA diagnostic biomarker TP53 human uncertain uncertain uncertain review 24729566 Recommendations for analyzing and reporting TP53 gene variants in the high-throughput sequencing era. 747 mRNA diagnostic biomarker "TCEA1,UBE2E1,XRCC5,IFIT1,MCM2,MCM7,CDC25A,SEC31A,CDK6" human uncertain meningioma "H(TCEA1,UBE2E1,XRCC5,IFIT1,MCM2,MCM7),L(CDC25A,SEC31A,CDK6)" original research 24724603 Meningioma protein-protein interaction network. 748 mRNA diagnostic biomarker MUC1 human tissue esophageal cancer uncertain original research 24718884 Specific MUC1 splice variants are correlated with tumor progression in esophageal cancer. 749 mRNA diagnostic biomarker TRO human tissue hepatocellular cancer H original research 24713374 "KIAA1114, a full-length protein encoded by the trophinin gene, is a novel surface marker for isolating tumor-initiating cells of multiple hepatocellular carcinoma subtypes." 750 mRNA diagnostic biomarker TPSG1 human uncertain pancreatic cancer uncertain review 24708694 The role of quantitative mass spectrometry in the discovery of pancreatic cancer biomarkers for translational science. 751 mRNA diagnostic biomarker TLR4 human uncertain colorectal cancer H original research 24705379 Role of toll-like receptor 4 in colorectal carcinogenesis: a meta-analysis. 752 mRNA diagnostic biomarker "POU5F1,NANOG,SOX2,ZFX,ESRRB,TCL1A,TBX3,DPPA4" human uncertain "bladder cancer,colon cancer,prostate cancer" H original research 24693477 "The expressions of stem cell markers: Oct4, Nanog, Sox2, nucleostemin, Bmi, Zfx, Tcl1, Tbx3, Dppa4, and Esrrb in bladder, colon, and prostate cancer, and certain cancer cell lines." 753 mRNA diagnostic biomarker "CD24,HMOX1,VCAM1,KCNA3" human tissue thyroid cancer parathyroid cancer uncertain original research 24681779 Gene identification of potential malignant parathyroid tumors phenotype in Chinese population. 754 mRNA diagnostic biomarker XRCC3 human uncertain uterine cancer L original research 24675091 Nuclear proteomics with XRCC3 knockdown to reveal the development of doxorubicin-resistant uterine cancer. 755 mRNA diagnostic biomarker "MSI1,MSI2" human uncertain stem cell cancer H original research 24671879 Developmental expression of Musashi-1 and Musashi-2 RNA-binding proteins during spermatogenesis: analysis of the deleterious effects of dysregulated expression. 756 mRNA diagnostic biomarker DSC3 human tissue prostate cancer L original research 24664224 Association of DSC3 mRNA down-regulation in prostate cancer with promoter hypermethylation and poor prognosis. 757 mRNA diagnostic biomarker RCAS1 human "tissue,serum" colorectal cancer H original research 24652591 The role of RCAS1 as a biomarker in diagnosing CRC and monitoring tumor recurrence and metastasis. 758 mRNA diagnostic biomarker PNST dog tissue nerve sheath tumor uncertain original research 24650889 Multiple polymerase chain reaction markers for the differentiation of canine cutaneous peripheral nerve sheath tumours versus canine fibrosarcomas. 759 mRNA diagnostic biomarker HS6ST2 human tissue colorectal cancer H original research 24649258 Overexpression of heparan sulfate 6-O-sulfotransferase-2 in colorectal cancer. 760 mRNA diagnostic biomarker "KRAS,GNAS,VHL,RNF43,CTNNB1" human uncertain pancreatic cancer H(KRAS) review 24639398 Utilization of ancillary studies in the cytologic diagnosis of biliary and pancreatic lesions: the Papanicolaou Society of Cytopathology guidelines for pancreatobiliary cytology. 761 mRNA diagnostic biomarker "S100A9,EGFR" human uncertain bladder cancer H original research 24631944 S100A9 and EGFR gene signatures predict disease progression in muscle invasive bladder cancer patients after chemotherapy. 762 mRNA diagnostic biomarker "ZFP57,CPT1A" human uncertain glioma glioblastoma H original research 24618825 "High grade glioblastoma is associated with aberrant expression of ZFP57, a protein involved in gene imprinting, and of CPT1A and CPT1C that regulate fatty acid metabolism." 763 mRNA diagnostic biomarker "SORBS1,SMAD4,HDAC2,RBL2,CDKN1B,CCND1" human tissue esophageal cancer uncertain original research 24604236 Pilot genome-wide study of tandem 3' UTRs in esophageal cancer using high-throughput sequencing. 764 mRNA diagnostic biomarker TP53 human uncertain uncertain H original research 24603336 Unequal prognostic potentials of p53 gain-of-function mutations in human cancers associate with drug-metabolizing activity. 765 mRNA diagnostic biomarker TP53INP1 human serum prostate cancer H original research 24600558 Development of an ELISA detecting Tumor Protein 53-Induced Nuclear Protein 1 in serum of prostate cancer patients. 766 mRNA diagnostic biomarker RET human uncertain thyroid cancer H original research 24599901 C-cell-derived calcitonin-free neuroendocrine carcinoma of the thyroid: the diagnostic importance of CGRP immunoreactivity. 767 mRNA diagnostic biomarker MMP9 human tissue breast cancer H original research 24596383 Expression of matrix metalloproteinases (MMPs) in primary human breast cancer: MMP-9 as a potential biomarker for cancer invasion and metastasis. 768 mRNA diagnostic biomarker FEN1 human tissue gastric cancer L original research 24590400 Flap endonuclease 1 is a promising candidate biomarker in gastric cancer and is involved in cell proliferation and apoptosis. 769 mRNA diagnostic biomarker HRG human tissue breast cancer H original research 24567057 Evaluation of histidine-rich glycoprotein tissue RNA and serum protein as novel markers for breast cancer. 770 mRNA diagnostic biomarker "IGF1,IGF2,SP1,CREB1" human uncertain prostate cancer H original research 24564736 Post genome-wide association studies functional characterization of prostate cancer risk loci. 771 mRNA diagnostic biomarker LAP2 human tissue uncertain H review 24563347 Lamina-associated polypeptide (LAP)2α and other LEM proteins in cancer biology. 772 mRNA diagnostic biomarker CAFS human uncertain "lungcancer,breast cancer" uncertain review 24560651 Prognostic relevance of cancer-associated fibroblasts in human cancer. 773 mRNA diagnostic biomarker TP53 mice uncertain neuroblastoma renal nephroblastoma H original research 24526816 Immunohistochemical Characterization of a Renal Nephroblastoma in a Trp53-mutant and Prolyl Isomerase 1-deficient Mouse. 774 mRNA diagnostic biomarker FFPE human tissue breast cancer H(Ki67) original research 24520381 Targeted biomarker profiling of matched primary and metastatic estrogen receptor positive breast cancers. 775 mRNA diagnostic biomarker CEACAM1 human uncertain lung cancer H original research 24518592 Gene expression profiling reveals GC and CEACAM1 as new tools in the diagnosis of lung carcinoids. 776 mRNA diagnostic biomarker TP63 human tissue lung cancer non-small cell lung cancer H original research 24509874 Potential utility of p63 expression in differential diagnosis of non-small-cell lung carcinoma and its effect on prognosis of the disease. 777 mRNA diagnostic biomarker "CTNNB1,MKI67,ERBB2,NEU" human tissue gastric cancer H original research 24507671 "Correlations of β-catenin, Ki67 and Her-2/neu with gastric cancer." 778 mRNA diagnostic biomarker CIP2A nude mice tissue colon cancer L original research 24493623 Temsirolimus enhances the efficacy of cetuximab in colon cancer through a CIP2A-dependent mechanism. 779 mRNA diagnostic biomarker VEGFA human tissue serosal cancer H original research 24491241 "Vascular endothelial growth factor, a novel and highly accurate pancreatic fluid biomarker for serous pancreatic cysts." 780 mRNA diagnostic biomarker ECT2 human uncertain lung cancer non-small cell lung cancer H original research 24484057 ECT2 amplification and overexpression as a new prognostic biomarker for early-stage lung adenocarcinoma. 781 mRNA diagnostic biomarker ALK human tissue uncertain L original research 24478382 Patterns of ALK expression in different human cancer types. 782 mRNA diagnostic biomarker PTEN human uncertain colorectal cancer L review 24475377 Functions and Regulation of the PTEN Gene in Colorectal Cancer. 783 mRNA diagnostic biomarker LTZS1 human tissue breast cancer L original research 24466374 Cytosine 5-Hydroxymethylation of the LZTS1 Gene Is Reduced in Breast Cancer. 784 mRNA diagnostic biomarker KRT20 human uncertain Merkel cell cancer H review 24463300 Modern management of Merkel cell carcinoma. 785 mRNA diagnostic biomarker YBX1 human uncertain melanoma H review 24461929 Y-box binding protein 1--a prognostic marker and target in tumour therapy. 786 mRNA diagnostic biomarker SPP1 human "tissue,blood" esophageal cancer esophageal squamous cell cancer H original research 24460294 Overexpressed ostepontin-c as a potential biomarker for esophageal squamous cell carcinoma. 787 mRNA diagnostic biomarker TP53 human serum pancreatic cancer H original research 24454372 Serum p53 Antibody Is Not Associated with p53 Immunoreactivity in Patients with Pancreatobiliary Cancers. 788 mRNA diagnostic biomarker KAT8 human tissue "colorectal cancer,gastric cancer,renal cancer" L original research 24452485 "Correlation of low expression of hMOF with clinicopathological features of colorectal carcinoma, gastric cancer and renal cell carcinoma." 789 mRNA diagnostic biomarker LIMP2 human uncertain prostate cancer H original research 24435746 Prostate cell lines as models for biomarker discovery: performance of current markers and the search for new biomarkers. 790 mRNA diagnostic biomarker "CD34,S100,CDKN2A" human tissue lipoblastoma H original research 24433523 Diagnostic utility of molecular and cytogenetic analysis in lipoblastoma: a study of two cases and review of the literature. 791 mRNA diagnostic biomarker PSMA human uncertain prostate cancer H original research 24424840 Functional prostate-specific membrane antigen is enriched in exosomes from prostate cancer cells. 792 mRNA diagnostic biomarker MKI67 human uncertain breast cancer H original research 24414612 Determination of proliferation in breast cancer by immunohistochemical detection of Ki-67. 793 mRNA diagnostic biomarker DNM2 human tissue prostate cancer H original research 24402972 "The significance of dynamin 2 expression for prostate cancer progression, prognostication, and therapeutic targeting." 794 mRNA diagnostic biomarker "CDK1,CDK2,CDK4,MCM2,MCM3,MCM4,EIF3A,RPN2" human tissue laryngeal cancer laryngeal squamous cell carcinoma L original research 24386425 Microarray gene expression analysis of tumorigenesis and regional lymph node metastasis in laryngeal squamous cell carcinoma. 795 mRNA diagnostic biomarker SATB2 human tissue osteosarcoma uncertain review 24384853 Novel uses of immunohistochemistry in the diagnosis and classification of soft tissue tumors. 796 mRNA diagnostic biomarker MLANA human uncertain adrenocortical cancer uncertain review 24382573 Pathology of the adrenal cortex: a reappraisal of the past 25 years focusing on adrenal cortical tumors. 797 mRNA diagnostic biomarker LIPH human "tissue,serum" lung cancer non-small cell lung cancer H original research 24380866 Lipase member H is a novel secreted protein selectively upregulated in human lung adenocarcinomas and bronchioloalveolar carcinomas. 798 mRNA diagnostic biomarker "GPC3,PEG10,SERPINI1,MDK" human "tissue,blood" hepatocellular cancer H original research 24369324 New genetic markers for diagnosis of hepatitis C related hepatocellular carcinoma in Egyptian patients. 799 mRNA diagnostic biomarker HGF human tissue bladder cancer H original research 24366484 Functional mononucleotide repeat polymorphism in the promoter region of HGF is associated with risk and malignant aggressiveness of bladder cancer. 800 mRNA diagnostic biomarker CHD1L human uncertain uncertain H review 24359616 CHD1L: a novel oncogene. 801 mRNA diagnostic biomarker PTTG1 human uncertain breast cancer H original research 24344401 "Pituitary tumor-transforming gene 1 is expressed in primary ductal breast carcinoma, lymph node infiltration, and distant metastases." 802 mRNA diagnostic biomarker MSLN human tissue lung cancer non-small cell lung cancer H original research 24334761 Mesothelin overexpression is a marker of tumor aggressiveness and is associated with reduced recurrence-free and overall survival in early-stage lung adenocarcinoma. 803 mRNA diagnostic biomarker SERPINF1 human uncertain pancreatic cancer H original research 24303806 Characterization of glycoproteins in pancreatic cyst fluid using a high-performance multiple lectin affinity chromatography platform. 804 mRNA diagnostic biomarker QUIRE human blood "renal cancer,ovarian Cancer" uncertain original research 24297536 An integrated approach to blood-based cancer diagnosis and biomarker discovery. 805 mRNA diagnostic biomarker B3GALNT2 human uncertain breast cancer H original research 24285400 Involvement of B3GALNT2 overexpression in the cell growth of breast cancer. 806 mRNA diagnostic biomarker HPEBP4 human uncertain breast cancer H original research 24276246 Phosphatidylethanolamine-binding protein 4 is associated with breast cancer metastasis through Src-mediated Akt tyrosine phosphorylation. 807 mRNA diagnostic biomarker SIX1 human tissue pancreatic cancer pancreatic ductal adenocarcinoma H original research 24263054 Sineoculis homeobox homolog 1 protein overexpression as an independent biomarker for pancreatic ductal adenocarcinoma. 808 mRNA diagnostic biomarker ALDH1 human tissue meningioma H original research 24252471 ALDH1 is an immunohistochemical diagnostic marker for solitary fibrous tumours and haemangiopericytomas of the meninges emerging from gene profiling study. 809 mRNA diagnostic biomarker ANKRD18B human "tissue,plasma sputum" lung cancer L original research 24249358 Epigenetic regulation of ANKRD18B in lung cancer. 810 mRNA diagnostic biomarker NAALADL2 human tissue prostate cancer H original research 24240687 N-acetyl-L-aspartyl-L-glutamate peptidase-like 2 is overexpressed in cancer and promotes a pro-migratory and pro-metastatic phenotype. 811 mRNA diagnostic biomarker "TARP,KRT5" human tissue uterine cancer endometrial cancer "H(TARP),L(KRT5)" original research 24238509 Value of T cell receptor gamma alternate reading frame protein and keratin 5 in endometrial carcinoma. 812 mRNA diagnostic biomarker TERT human uncertain urogenital cancer H original research 24215939 Telomerase reverse transcriptase gene promoter mutations help discern the origin of urogenital tumors: a genomic and molecular study. 813 mRNA diagnostic biomarker PCA3 human urine prostate cancer H original research 24211598 Prostate cancer biomarker profiles in urinary sediments and exosomes. 814 mRNA diagnostic biomarker PPM human "tissue,urine" prostate cancer uncertain original research 24206626 Gene expression profiles in prostate cancer: identification of candidate non-invasive diagnostic markers. 815 mRNA diagnostic biomarker EGFR human uncertain oral cancer H review 24179398 Can immunohistochemistry serve as an alternative to subjective histopathological diagnosis of oral epithelial dysplasia? 816 mRNA diagnostic biomarker "EGFR,TERT" human plasma lung cancer non-small cell lung cancer H original research 24179385 EGFR and hTERT Expression as a Diagnostic Approach for Non-small Cell Lung Cancer in High Risk Groups. 817 mRNA diagnostic biomarker PI3KCA human tissue breast cancer uncertain original research 24175777 Phosphatidylinositol 3-kinase (PI3KCA) oncogene mutation analysis and gene expression profiling in primary breast cancer patients. 818 mRNA diagnostic biomarker TP53 human uncertain neuroblastoma H original research 24173829 "S(+)-ibuprofen destabilizes MYC/MYCN and AKT, increases p53 expression, and induces unfolded protein response and favorable phenotype in neuroblastoma cell lines." 819 mRNA diagnostic biomarker HOXB13 human tissue prostate cancer H original research 24146108 "HOXB13 is a sensitive and specific marker of prostate cells, useful in distinguishing between carcinomas of prostatic and urothelial origin." 820 mRNA diagnostic biomarker "ERC,MSLN" human "tissue,serum" gastric cancer uncertain original research 24146039 ERC/mesothelin is expressed in human gastric cancer tissues and cell lines. 821 mRNA diagnostic biomarker IGFBP7 human serum hepatocellular cancer hepatitis B virus-associated hepatocellular carcinoma H original research 24142767 Methylation of serum insulin-like growth factor-binding protein 7 promoter in hepatitis B virus-associated hepatocellular carcinoma. 822 mRNA diagnostic biomarker "VEGF,HIF1,CA9,STC1" human "tissue,serum" ovarian cancer L original research 24137335 "A potential diagnostic marker for ovarian cancer: Involvement of the histone acetyltransferase, human males absent on the first." 823 mRNA diagnostic biomarker SPOCK1 human tissue lung cancer H original research 24134845 SPOCK1 is a novel transforming growth factor-β target gene that regulates lung cancer cell epithelial-mesenchymal transition. 824 mRNA diagnostic biomarker PSMA human tissue prostate cancer H original research 24130224 Prostate-specific membrane antigen protein expression in tumor tissue and risk of lethal prostate cancer. 825 mRNA diagnostic biomarker BORIS human tissue prostate cancer H original research 24123052 Expression of the cancer-testis antigen BORIS correlates with prostate cancer. 826 mRNA diagnostic biomarker "APC,GSTP1,RPP14,CDKN2A,TIMP3,PTGS2" human serum renal cancer H original research 24123044 Serum DNA hypermethylation in patients with kidney cancer: results of a prospective study. 827 mRNA diagnostic biomarker VEGFA human tissue uncertain H original research 24114200 VEGFA gene locus analysis across 80 human tumour types reveals gene amplification in several neoplastic entities. 828 mRNA diagnostic biomarker MGMT human uncertain glioma glioblastoma L review 24109190 Personalized treatment strategies in glioblastoma: MGMT promoter methylation status. 829 mRNA diagnostic biomarker CDC73 human uncertain adenoid cystic cancer atypical parathyroid adenoma H original research 24081804 Negative parafibromin staining predicts malignant behavior in atypical parathyroid adenomas. 830 mRNA diagnostic biomarker LGR5 human tissue colon cancer H original research 24063790 Over-expression of LGR5 correlates with poor survival of colon cancer in mice as well as in patients. 831 mRNA diagnostic biomarker CBS human tissue colorectal cancer H original research 24054011 [Correlation of methylation of CpG island in cystathionine beta synthase promoter and clinicopathological features in colorectal cancer]. 832 mRNA diagnostic biomarker "EDN,RB1,HJURP,ARHGEF5,CHAF1A" human uncertain glioma "L(EDN/Rb,HJURP,p60/CAF-1,PDLI4)" original research 24039914 "Prognostic significance of EDN/RB, HJURP, p60/CAF-1 and PDLI4, four new markers in high-grade gliomas." 833 mRNA diagnostic biomarker "CARD9,CARD10,COP" human tissue hepatocellular cancer H original research 24018495 Caspase recruitment domains. New potential markers for diagnosis of hepatocellular carcinoma associated with HCV in Egyptian patients. 834 mRNA diagnostic biomarker SALL4 human serum hepatocellular cancer H original research 24012616 The transcription factor SALL4 regulates stemness of EpCAM-positive hepatocellular carcinoma. 835 mRNA diagnostic biomarker RASSF1A human uncertain lung cancer non-small cell lung cancer L original research 24011511 Effect of DNA methylation inhibitor on RASSF1A genes expression in non-small cell lung cancer cell line A549 and A549DDP. 836 mRNA diagnostic biomarker "HPVL1,HTERC" human cell cervical cancer "H(HTERC),L(HPVL1)" original research 23997907 Detention of HPV L1 Capsid Protein and hTERC Gene in Screening of Cervical Cancer. 837 mRNA diagnostic biomarker WT1 human tissue astrocytoma H original research 23977661 WT1 protein expression in astrocytic tumors and its relationship with cellular proliferation index. 838 mRNA diagnostic biomarker PRKD1 human tissue breast cancer L original research 23971832 Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis. 839 mRNA diagnostic biomarker "EML4,ALK,KIF5B" human tissue lung cancer non-small cell lung cancer H original research 23951022 "Comparison of IHC, FISH and RT-PCR methods for detection of ALK rearrangements in 312 non-small cell lung cancer patients in Taiwan." 840 mRNA diagnostic biomarker "PTEN,EGFR" human tissue colorectal cancer "H(EGFR),L(PTEN)" original research 23934607 Alterations in the EGFR pathway coincide in colorectal cancer and impact on prognosis. 841 mRNA diagnostic biomarker PRDX2 human tissue osteosarcoma H original research 23911960 Proteomics study of open biopsy samples identifies peroxiredoxin 2 as a predictive biomarker of response to induction chemotherapy in osteosarcoma. 842 mRNA diagnostic biomarker "HPN,CLU1,WT1,WNT5A,AURKA,SPARC" human uncertain prostate cancer H(CLU1) review 23878130 Prostate cancer invasion and metastasis: insights from mining genomic data. 843 mRNA diagnostic biomarker BMI1 human tissue breast cancer invasive ductal breast carcinoma L original research 23873108 Regulation of BMI1 Polycomb gene expression in histological grades of invasive ductal breast carcinomas and its correlation with hormone receptor status. 844 mRNA diagnostic biomarker GJA1 human uncertain germ cell cancer L review 23865425 The emerging role of connexin 43 in testis pathogenesis. 845 mRNA diagnostic biomarker SYK human tissue esophageal cancer esophageal squamous cell carcinoma L original research 23865365 Expression of putative tumor suppressor gene spleen tyrosine kinase in esophageal squamous cell carcinoma. 846 mRNA diagnostic biomarker SHOX2 human tissue hepatocellular cancer H original research 23851611 Elevated SHOX2 expression is associated with tumor recurrence of hepatocellular carcinoma. 847 mRNA diagnostic biomarker "TNF,CA153" human serum cervical cancer H original research 23850705 Prognostic value of combined serum biomarkers in predicting outcomes in cervical cancer patients. 848 mRNA diagnostic biomarker DPEP1 human tissue colorectal cancer H original research 23839495 Dipeptidase 1 (DPEP1) is a marker for the transition from low-grade to high-grade intraepithelial neoplasia and an adverse prognostic factor in colorectal cancer. 849 mRNA diagnostic biomarker RFX6 human uncertain prostate cancer uncertain original research 23803082 Susceptibility loci associations with prostate cancer risk in northern Chinese men 850 mRNA diagnostic biomarker "HTATIP2,TIP30" human "tissue,serum" ovarian cancer serous ovarian cancer H original research 23800048 High serum HTATIP2/TIP30 level in serous ovarian cancer as prognostic or diagnostic marker. 851 mRNA diagnostic biomarker RPL22 human "tissue,plasma " lung cancer non-small cell lung cancer L original research 23797773 Down-regulation of ribosomal protein L22 in non-small cell lung cancer. 852 mRNA diagnostic biomarker FHIT human uncertain colorectal cancer L original research 23797051 Reduced FHIT expression is associated with mismatch repair deficient and high CpG island methylator phenotype colorectal cancer. 853 mRNA diagnostic biomarker CD164 human uncertain lymphoma cutaneous T-cell lymphoma H original research 23792457 CD164 and FCRL3 are highly expressed on CD4+CD26- T cells in Sézary syndrome patients. 854 mRNA diagnostic biomarker SEMA6B human tissue gastric cancer H original research 23781008 The role of axon guidance factor semaphorin 6B in the invasion and metastasis of gastric cancer. 855 mRNA diagnostic biomarker TP53 human uncertain cervical cancer H review 23777477 Molecular biomarkers in cervical cancer diagnosis: a critical appraisal. 856 mRNA diagnostic biomarker GRIA2 human tissue fibromatose H original research 23761323 "Comprehensive genetic analysis identifies a pathognomonic NAB2/STAT6 fusion gene, nonrandom secondary genomic imbalances, and a characteristic gene expression profile in solitary fibrous tumor." 857 mRNA diagnostic biomarker BPIFA1 human uncertain lung cancer H original research 23759037 Superiority and clinical significance of Lunx mRNA in the diagnosis of malignant pleural effusion caused by pulmonary carcinoma. 858 mRNA diagnostic biomarker TPX2 human tissue esophageal cancer esophageal squamous cell carcinoma H original research 23725757 Upregulation of the TPX2 gene is associated with enhanced tumor malignance of esophageal squamous cell carcinoma. 859 mRNA diagnostic biomarker "MYB,NFIB" human uncertain adenoid cystic cancer lacrimal adenoid cystic carcinoma uncertain original research 23725736 "Adenoid cystic carcinoma of the lacrimal gland: MYB gene activation, genomic imbalances, and clinical characteristics." 860 mRNA diagnostic biomarker "TERT,HGF" human serum bladder cancer H original research 23724620 Evaluation of urinary human telomerase reverse transcriptase mRNA and scatter factor protein as urine markers for diagnosis of bladder cancer. 861 mRNA diagnostic biomarker "SULF1,INTS8,ATP6V1C,GPR172A" human tissue gastric cancer H(SULF1) original research 23722107 A 4-gene panel as a marker at chromosome 8q in Asian gastric cancer patients. 862 mRNA diagnostic biomarker MSGS human uncertain pancreatic cancer pancreatic ductal adenocarcinoma L original research 23718921 Epigenetic regulation and role of metastasis suppressor genes in pancreatic ductal adenocarcinoma. 863 mRNA diagnostic biomarker IL19 human uncertain breast cancer H review 23710200 Interleukin-19 in breast cancer. 864 mRNA diagnostic biomarker "FHIT,CDKN2A" human tissue lung cancer L original research 23709347 Detection of FHIT and p16 mRNA deletion in biopsy specimens obtained by bronchoscopy for the diagnosis of lung cancer. 865 mRNA diagnostic biomarker "FLT1,FLT4,HPSE,HIF1A,HBEGF,PDGFA,PDAP1,EGFR" human tissue cholangio cancer L(FLT1) original research 23704979 "EGFR, FLT1 and heparanase as markers identifying patients at risk of short survival in cholangiocarcinoma." 866 mRNA diagnostic biomarker SNCG human uncertain breast cancer triple-negative breast cancer H original research 23696021 Expression of synuclein gamma indicates poor prognosis of triple-negative breast cancer. 867 mRNA diagnostic biomarker PAK5 human tissue hepatocellular cancer H original research 23685956 P21-activated kinase 5 plays essential roles in the proliferation and tumorigenicity of human hepatocellular carcinoma. 868 mRNA diagnostic biomarker QSOX1 mice uncertain breast cancer H review 23680167 Illuminating luminal B: QSOX1 as a subtype-specific biomarker. 869 mRNA diagnostic biomarker MAGEA human tissue "gastric cancer,colorectal cancer" H original research 23673898 Melanoma antigen gene family A as a molecular marker of gastric and colorectal cancers. 870 mRNA diagnostic biomarker "RPL18A,S100A4,PRG1,SUB1,S100A6,RPS7,RPL11,PFN1,LOC23117,TYROBP,TIMP1,SERF2,YWHAZ,LSM7,GSTP1,SNRPD2,LOC392501,OAZ1,POLR2J,EIF5A,ATP5H,APOC1,LGALS1,S100A11,C1QB,RPS10,HSPA8,NUTF2,PRKDC,NOLA3,TCEB2,NEDD8,RPL36,VIM,STK17A,NDUFS8,SELT,CST3,Symbol,ATP1B1,NGFRAP1,FOXJ3,CD24,SCAMP1,SEC22B,ITM2B,PDIA3,PIN4,KRAS,DICER1,SWAP70,VAPA" human uncertain uncertain uncertain original research 23671674 A microarray-based gene expression analysis to identify diagnostic biomarkers for unknown primary cancer. 871 mRNA diagnostic biomarker PMMTI human tissue mesenchymal cancer H original research 23669733 A case with sacrococcygeal primitive myxoid mesenchymal tumor of infancy: a case report and review of the literature. 872 mRNA diagnostic biomarker "RASSF1A,RUNX3" human tissue gastric cancer uncertain review 23669186 Gene methylation in gastric cancer. 873 mRNA diagnostic biomarker KLK3 human tissue prostate cancer H review 23667899 Genetic polymorphisms in the human tissue kallikrein (KLK) locus and their implication in various malignant and non-malignant diseases. 874 mRNA diagnostic biomarker BTG3 human tissue ovarian cancer L original research 23657964 "Decreased expression of BTG3 was linked to carcinogenesis, aggressiveness, and prognosis of ovarian carcinoma." 875 mRNA diagnostic biomarker "EGFR,FGFR2,FGFR3,IL8,PTPRF,TNC,CXCL13,COL11A1,CHP2,SHC4,PPP2R2C,WNT4" human uncertain melanoma "H(PTPRF,CXCL13,COL11A1,SHC4)" original research 23638386 A new 12-gene diagnostic biomarker signature of melanoma revealed by integrated microarray analysis. 876 mRNA diagnostic biomarker "IGFBP7,TFE3" human tissue renal cancer uncertain original research 23628822 Xp11.2 translocation renal cell carcinoma with PSF-TFE3 rearrangement. 877 mRNA diagnostic biomarker ISG15 human tissue oral cancer oral squamous cell carcinoma H original research 23621203 Interferon stimulated gene-ISG15 is a potential diagnostic biomarker in oral squamous cell carcinomas. 878 mRNA diagnostic biomarker KLK15 human tissue prostate cancer H original research 23620432 Quantified KLK15 gene expression levels discriminate prostate cancer from benign tumors and constitute a novel independent predictor of disease progression. 879 mRNA diagnostic biomarker RBX1 human tissue bladder cancer H original research 23609182 Overexpression of RING box protein-1 (RBX1) associated with poor prognosis of non-muscle-invasive bladder transitional cell carcinoma. 880 mRNA diagnostic biomarker FUT1 human tissue hepatocellular cancer HBV related-hepatocellular carcinoma L original research 23601182 Clinical significance and gene expression study of human hepatic stellate cells in HBV related-hepatocellular carcinoma. 881 mRNA diagnostic biomarker TP53 human tissue colorectal cancer H original research 23596757 The high expression of p53 in sporadic colorectal carcinoma is associated with metastasis and decreased survival. 882 mRNA diagnostic biomarker "TP53,CTNNB1,PIK3CA" human uncertain hepatocellular cancer uncertain review 23583669 "Mutations in TP53, CTNNB1 and PIK3CA genes in hepatocellular carcinoma associated with hepatitis B and hepatitis C virus infections." 883 mRNA diagnostic biomarker ULK1 human tissue hepatocellular cancer H original research 23573318 UNC51-like kinase 1 as a potential prognostic biomarker for hepatocellular carcinoma. 884 mRNA diagnostic biomarker GPC3 human tissue hepatocellular cancer H original research 23558072 Values of circulating GPC-3 mRNA and alpha-fetoprotein in detecting patients with hepatocellular carcinoma. 885 mRNA diagnostic biomarker "UCHL1,RUNX3" human tissue pancreatobiliary cancer L review 23555160 Cancer detection by ubiquitin carboxyl-terminal esterase L1 methylation in pancreatobiliary fluids. 886 mRNA diagnostic biomarker QSOX1 human tissue breast cancer H original research 23536962 Expression of quiescin sulfhydryl oxidase 1 is associated with a highly invasive phenotype and correlates with a poor prognosis in Luminal B breast cancer. 887 mRNA diagnostic biomarker ATF3 human uncertain bladder cancer L original research 23536558 ATF3 suppresses metastasis of bladder cancer by regulating gelsolin-mediated remodeling of the actin cytoskeleton. 888 mRNA diagnostic biomarker "FHIT,WWOX" human tissue nasopharyngeal cancer L original research 23534718 Expression of fragile histidine triad (FHIT) and WW-domain oxidoreductase gene (WWOX) in nasopharyngeal carcinoma. 889 mRNA diagnostic biomarker TCF21 human tissue head and neck cancer head and neck squamous cell cancer H original research 23529585 Protein expression and promoter methylation of the candidate biomarker TCF21 in head and neck squamous cell carcinoma. 890 mRNA diagnostic biomarker SPINK1 human uncertain hepatocellular cancer H original research 23527199 Global gene expression profiling reveals SPINK1 as a potential hepatocellular carcinoma marker. 891 mRNA diagnostic biomarker CBX5 human tissue prostate cancer H original research 23522301 HP1γ expression is elevated in prostate cancer and is superior to Gleason score as a predictor of biochemical recurrence after radical prostatectomy. 892 mRNA diagnostic biomarker "ALOX15,TNFAIP6,CRISP3,SLURP1,FLG" human tissue esophageal cancer eosinophilic esophagitis "H(ALOX15,TNFAIP6),L(CRISP3,SLURP1,FLG)" original research 23503644 Expression microarray analysis identifies novel epithelial-derived protein markers in eosinophilic esophagitis. 893 mRNA diagnostic biomarker PRDX2 human tissue breast cancer H original research 23497519 Endoplasmic reticulum stress induces PRNP prion protein gene expression in breast cancer. 894 mRNA diagnostic biomarker CDKN2A human tissue head and neck cancer head and neck squamous cell cancer H original research 23482761 The role of p16 expression as a predictive marker in HPV-positive oral SCCHN--a retrospective single-center study. 895 mRNA diagnostic biomarker AKAP4 human tissue cervical cancer H original research 23478221 Expression and humoral response of A-kinase anchor protein 4 in cervical cancer. 896 mRNA diagnostic biomarker SSX2IP human uncertain hepatocellular cancer H original research 23452395 SSX2IP promotes metastasis and chemotherapeutic resistance of hepatocellular carcinoma. 897 mRNA diagnostic biomarker "TFE3,PGR" human uncertain "melanoma,mesenchymal cancer" uncertain original research 23451753 Transcription factor E3 protein-positive perivascular epithelioid cell tumor of the appendix presenting as acute appendicitis: a case report and review of the literature. 898 mRNA diagnostic biomarker AKAP4 human tissue breast cancer H original research 23451156 "A novel cancer testis antigen, A-kinase anchor protein 4 (AKAP4) is a potential biomarker for breast cancer." 899 mRNA diagnostic biomarker "CD44,OTP" human tissue lung cancer L original research 23444222 CD44 and OTP are strong prognostic markers for pulmonary carcinoids. 900 mRNA diagnostic biomarker HAP1 human tissue breast cancer L original research 23440330 Huntingtin-associated protein 1: a potential biomarker of breast cancer. 901 mRNA diagnostic biomarker PLAC1 human uncertain uncertain H original research 23434395 Preliminary evidence for high anti-PLAC1 antibody levels in infertile patients with repeated unexplained implantation failure. 902 mRNA diagnostic biomarker ERBB2 human tissue breast cancer H original research 23421821 Negative transcriptional control of ERBB2 gene by MBP-1 and HDAC1: diagnostic implications in breast cancer. 903 mRNA diagnostic biomarker NTSR1 human tissue ovarian cancer H original research 23407681 Ectopic Expression of Sortilin 1 (NTR-3) in Patients with Ovarian Carcinoma. 904 mRNA diagnostic biomarker EPCAM human uncertain ovarian cancer H original research 23403823 Bidirectional modulation of endogenous EpCAM expression to unravel its function in ovarian cancer. 905 mRNA diagnostic biomarker ERG human tissue prostate cancer H review 23399797 Clinical applications of novel ERG immunohistochemistry in prostate cancer diagnosis and management. 906 mRNA diagnostic biomarker "PTGER4,PHLDA1,CK15,KRT19,PHLDA1" human uncertain microcystic adnexal carcinoma uncertain original research 23398472 "The immunohistochemical differential diagnosis of microcystic adnexal carcinoma, desmoplastic trichoepithelioma and morpheaform basal cell carcinoma using BerEP4 and stem cell markers." 907 mRNA diagnostic biomarker "PAX8,PPAR" human tissue thyroid cancer follicular thyroid tumor uncertain original research 23397760 PAX8-PPARgamma oncogene in follicular thyroid tumors: RT-PCR and immunohistochemical analyses. 908 mRNA diagnostic biomarker "ESR1,PGR,ERBB2" human uncertain breast cancer uncertain original research 23397283 The detection of ESR1/PGR/ERBB2 mRNA levels by RT-QPCR: a better approach for subtyping breast cancer and predicting prognosis. 909 mRNA diagnostic biomarker TP53 human serum lung cancer H original research 23384026 Serum p53 antibody detection in patients with impaired lung function. 910 mRNA diagnostic biomarker ETS human uncertain prostate cancer uncertain review 23357671 Truncated ERG proteins affect the aggressiveness of prostate cancer. 911 mRNA diagnostic biomarker TYMS human tissue lung cancer non-small cell lung cancer H original research 23350714 Association of thymidylate synthase gene 3'-untranslated region polymorphism with sensitivity of non-small cell lung cancer to pemetrexed treatment: TS gene polymorphism and pemetrexed sensitivity in NSCLC. 912 mRNA diagnostic biomarker EGFR human uncertain lung cancer non-small cell lung cancer H original research 23336484 [Epithelial growth factor receptor mutation status to the effective of survival in non-small cell lung cancer after surgery]. 913 mRNA diagnostic biomarker SATB1 human uncertain astrocytoma H original research 23317753 Relationship between SATB1 expression and prognosis in astrocytoma. 914 mRNA diagnostic biomarker GATA6 human tissue cholangio cancer H original research 23313142 Aberrant expression of GATA binding protein 6 correlates with poor prognosis and promotes metastasis in cholangiocarcinoma. 915 mRNA diagnostic biomarker BTG2 human uncertain bladder cancer H original research 23299537 Endogenous BTG2 expression stimulates migration of bladder cancer cells and correlates with poor clinical prognosis for bladder cancer patients. 916 mRNA diagnostic biomarker "KRT8,CK18,KRT19" human tissue breast cancer H original research 23299436 Detection of tumor cell-specific mRNA in the peripheral blood of patients with breast cancer—evaluation of several markers with real-time reverse transcription-PCR. 917 mRNA diagnostic biomarker "CHUK,INSR,CREBBP" human uncertain breast cancer uncertain original research 23275709 Network biology approach for identifying key regulatory genes by expression based study of breast cancer. 918 mRNA diagnostic biomarker HLA-G human uncertain thyroid cancer papillary thyroid cancer H original research 23261411 Association between the HLA-G molecule and lymph node metastasis in papillary thyroid cancer. 919 mRNA diagnostic biomarker CALCA human blood thyroid cancer medullary thyroid cancer H original research 23259706 Measurement of calcitonin and calcitonin gene-related peptide mRNA refines the management of patients with medullary thyroid cancer and may replace calcitonin-stimulation tests. 920 mRNA diagnostic biomarker ERBB3 human uncertain breast cancer H(His-2) original research 23255937 Accurate breast cancer diagnosis through real-time PCR her-2 gene quantification using immunohistochemically-identified biopsies. 921 mRNA diagnostic biomarker "PARK2,WNT7A,SMARCA2,FRAP1,CDKN2A,CCND1,EGFR,EGFR,EGF,PARK2,PTEN,CACNA2D2,CDH1" human uncertain lung cancer non-small cell lung cancer uncertain original research 23237220 Using the theory of coevolution to predict protein-protein interactions in non-small cell lung cancer. 922 mRNA diagnostic biomarker KLK12 human tissue gastric cancer H original research 23236234 Clinical significance of human kallikrein 12 gene expression in gastric cancer. 923 mRNA diagnostic biomarker PRODH human uncertain gastric cancer H original research 23232983 Metabolomic analysis of dynamic response and drug resistance of gastric cancer cells to 5-fluorouracil. 924 mRNA diagnostic biomarker MAL human uncertain oral cancer oral squamous cell carcinoma L original research 23224601 Expression of myelin and lymphocyte protein (MAL) in oral carcinogenesis. 925 mRNA diagnostic biomarker "KLK7,KLK14" human tissue colon cancer H original research 23224034 Parallel overexpression and clinical significance of kallikrein-related peptidases 7 and 14 (KLK7KLK14) in colon cancer. 926 mRNA diagnostic biomarker PML human tissue cervical cancer L original research 23220564 Downregulation of tumor suppressor gene PML in uterine cervical carcinogenesis: impact of human papillomavirus infection (HPV). 927 mRNA diagnostic biomarker EGR human urine prostate cancer uncertain original research 23201468 Prospective multicentre evaluation of PCA3 and TMPRSS2-ERG gene fusions as diagnostic and prognostic urinary biomarkers for prostate cancer. 928 mRNA diagnostic biomarker MZB1 human uncertain leukemia H original research 23189934 "High expression of MZB1 predicts adverse prognosis in chronic lymphocytic leukemia, follicular lymphoma and diffuse large B-cell lymphoma and is associated with a unique gene expression signature." 929 mRNA diagnostic biomarker TIMELESS human tissue lung cancer H original research 23173913 TIMELESS is overexpressed in lung cancer and its expression correlates with poor patient survival. 930 mRNA diagnostic biomarker ERCC1 human tissue lung cancer H original research 23171216 Using protein microarray technology to screen anti-ERCC1 monoclonal antibodies for specificity and applications in pathology. 931 mRNA diagnostic biomarker S100 human uncertain "colorectal cancer,hepatocellular cancer" H review 23166536 S100 proteins as diagnostic and prognostic markers in colorectal and hepatocellular carcinoma. 932 mRNA diagnostic biomarker BRAF human serum thyroid cancer papillary thyroid carcinoma uncertain original research 23161556 Study of peripheral BRAF(V600E) mutation as a possible novel marker for papillary thyroid carcinomas. 933 mRNA diagnostic biomarker CBS human tissue gastrointestinal cancer L original research 23152928 Frequent epigenetic silencing of the folate-metabolising gene cystathionine-beta-synthase in gastrointestinal cancer. 934 mRNA diagnostic biomarker TYMS human uncertain ovarian cancer epithelial ovarian cancer H original research 23148637 Polymorphic thymidylate synthase gene impacts on overall survival of patients with epithelial ovarian cancer after platinum-based chemotherapy. 935 mRNA diagnostic biomarker ANXA2 human "tissue,serum" hepatocellular cancer H original research 23139605 Expression characteristics and diagnostic value of annexin A2 in hepatocellular carcinoma. 936 mRNA diagnostic biomarker DKK1 human tissue cholangio cancer intrahepatic cholangiocarcinoma H original research 23132676 High expression of Dickkopf-related protein 1 is related to lymphatic metastasis and indicates poor prognosis in intrahepatic cholangiocarcinoma patients after surgery. 937 mRNA diagnostic biomarker TRA16 human tissue lung cancer non-small cell lung cancer H original research 23129017 Testicular orphan nuclear receptor 4-associated protein 16 promotes non-small cell lung carcinoma by activating estrogen receptor β and blocking testicular orphan nuclear receptor 2. 938 mRNA diagnostic biomarker HMOX1 human cell uncertain H original research 23115410 The expression of heme oxygenase-1 in human-derived cancer cell lines. 939 mRNA diagnostic biomarker "TXN,TXNIP" human tissue gastric cancer L(TXNIP) original research 23112551 Thioredoxin and thioredoxin-interacting protein as prognostic markers for gastric cancer recurrence. 940 mRNA diagnostic biomarker WT1 human blood leukaemia L original research 23111196 Reduction in WT1 gene expression during early treatment predicts the outcome in patients with acute myeloid leukemia. 941 mRNA diagnostic biomarker EBP1 human tissue salivary cancer salivary adenoid cystic carcinoma H original research 23110497 Expression of ERBB3 binding protein 1 (EBP1) in salivary adenoid cystic carcinoma and its clinicopathological relevance. 942 mRNA diagnostic biomarker NNMT human "tissue,urine" bladder cancer H original research 23097023 Upregulation of tissue and urinary nicotinamide N-methyltransferase in bladder cancer: potential for the development of a urine-based diagnostic test. 943 mRNA diagnostic biomarker ELTD1 human tissue glioma H original research 23096411 "ELTD1, a potential new biomarker for gliomas." 944 mRNA diagnostic biomarker TBX3 human tissue head and neck cancer head and neck squamous cell cancer H original research 23082988 Tbx3 represses PTEN and is over-expressed in head and neck squamous cell carcinoma. 945 mRNA diagnostic biomarker "SALL3,SALL4" human uncertain stromal tumor gonadal stromal cancer uncertain original research 23074379 N-cadherin Expression in Testicular Germ Cell and Gonadal Stromal Tumors. 946 mRNA diagnostic biomarker "CLIC1,MSH5" human uncertain prostate cancer uncertain original research 23071848 Blood-based biomarkers of aggressive prostate cancer. 947 mRNA diagnostic biomarker H3K27 human tissue renal cancer L original research 23057811 Expression and significance of histone H3K27 demethylases in renal cell carcinoma. 948 mRNA diagnostic biomarker TNIP1 human uncertain leukaemia L original research 23056078 Gene polymorphisms of ABC transporters are associated with clinical outcomes in children with acute lymphoblastic leukemia. 949 mRNA diagnostic biomarker "JAK2,TET2,IDH2,ASXL1,IDH1" human uncertain myeloma myeloproliferative neoplasm uncertain review 23049404 Philadelphia-negative chronic myeloproliferative neoplasms. 950 mRNA diagnostic biomarker TRIM59 human tissue uncertain H original research 23048060 "TRIM59, a novel multiple cancer biomarker for immunohistochemical detection of tumorigenesis." 951 mRNA diagnostic biomarker TSLC1 human uncertain melanoma cutaneous melanoma L original research 23047161 TSLC1 expression discriminates cutaneous melanomas from dysplastic nevi. 952 mRNA diagnostic biomarker MIDS human tissue squamous cell cancer uncertain original research 23034676 Exploiting FOXM1-orchestrated molecular network for early squamous cell carcinoma diagnosis and prognosis. 953 mRNA diagnostic biomarker SETD2 human tissue oral cancer oral squamous cell carcinoma L(HIF1-α) original research 23028863 HIF1-alpha expression predicts survival of patients with squamous cell carcinoma of the oral cavity. 954 mRNA diagnostic biomarker AMY1A human "saliva,cell" oral cancer uncertain review 23024467 A review on salivary genomics and proteomics biomarkers in oral cancer. 955 mRNA diagnostic biomarker UBE4B human tissue nephroblastoma L original research 22990745 UBE4B levels are correlated with clinical outcomes in neuroblastoma patients and with altered neuroblastoma cell proliferation and sensitivity to epidermal growth factor receptor inhibitors. 956 mRNA diagnostic biomarker OAT human tissue lung cancer non-small cell lung cancer H original research 22989455 Expression and bioinformatic analysis of ornithine aminotransferase in non-small cell lung cancer. 957 mRNA diagnostic biomarker CEACAM6 human tissue colorectal cancer H original research 22975528 Overexpression and clinical significance of carcinoembryonic antigen-related cell adhesion molecule 6 in colorectal cancer. 958 mRNA diagnostic biomarker "KIT,CDH1,LSM7,TMEM50B,DDI2,TC1,BRAF" human tissue thyroid cancer uncertain original research 22958914 A molecular computational model improves the preoperative diagnosis of thyroid nodules. 959 mRNA diagnostic biomarker HPSE human tissue hepatocellular cancer L original research 22952874 Allele loss and down-regulation of heparanase gene are associated with the progression and poor prognosis of hepatocellular carcinoma. 960 mRNA diagnostic biomarker FOXM1 human tissue cervical cancer H original research 22943878 FOXM1 promotes tumor cell invasion and correlates with poor prognosis in early-stage cervical cancer. 961 mRNA diagnostic biomarker LMLN human uncertain gastrointestinal cancer L review 22939997 SPARC and DNA methylation: possible diagnostic and therapeutic implications in gastrointestinal cancers. 962 mRNA diagnostic biomarker HOXD3 human uncertain breast cancer H original research 22935821 Expression of HOXD3 correlates with shorter survival in patients with invasive breast cancer. 963 mRNA diagnostic biomarker "LNCAP,BTG2" human uncertain uncertain uncertain original research 22924825 Development of a method to measure DNA methylation levels by using methyl CpG-binding protein and luciferase-fused zinc finger protein. 964 mRNA diagnostic biomarker ZFP36 human tissue breast cancer L original research 22907529 Genetic polymorphisms in RNA binding proteins contribute to breast cancer survival. 965 mRNA diagnostic biomarker TP53 human uncertain breast cancer H review 22901112 Recent candidate molecular markers: vitamin D signaling and apoptosis specific regulator of p53 (ASPP) in breast cancer. 966 mRNA diagnostic biomarker WAVE human uncertain uncertain H review 22901110 WAVEs: a novel and promising weapon in the cancer therapy tool box. 967 mRNA diagnostic biomarker "VEGFA,FGF2" human tissue bladder cancer bladder urothelial carcinoma H original research 22895562 "Role of the angiogenic components, VEGFA, FGF2, OPN and RHOC, in urothelial cell carcinoma of the urinary bladder." 968 mRNA diagnostic biomarker ILK human tissue pancreatic cancer H original research 22888305 "Silencing of the integrin-linked kinase gene suppresses the proliferation, migration and invasion of pancreatic cancer cells (Panc-1)." 969 mRNA diagnostic biomarker RRM2 human tissue ovarian cancer H original research 22884145 Overexpression of catalytic subunit M2 in patients with ovarian cancer. 970 mRNA diagnostic biomarker UTF1 human uncertain cervical cancer H original research 22880087 Aberrant promoter methylation and expression of UTF1 during cervical carcinogenesis. 971 mRNA diagnostic biomarker "IGF2BP3,NEK2,HOXB7" human uncertain cholangio cancer H original research 22879911 "Detection of IGF2BP3, HOXB7, and NEK2 mRNA expression in brush cytology specimens as a new diagnostic tool in patients with biliary strictures." 972 mRNA diagnostic biomarker RBM5 human tissue lung cancer non-small cell lung cancer L original research 22866867 The tumor suppressor gene RBM5 inhibits lung adenocarcinoma cell growth and induces apoptosis. 973 mRNA diagnostic biomarker BRAF human uncertain thyroid cancer papillary thyroid carcinoma uncertain review 22863493 BRAF gene mutation in the natural history of papillary thyroid carcinoma: diagnostic and prognostic implications. 974 mRNA diagnostic biomarker KLF6 human tissue osteosarcoma L original research 22855058 Expression and significance of Kruppel-like factor 6 gene in osteosarcoma. 975 mRNA diagnostic biomarker "JAM3,EPB41L3,TERT,AHI1" human "tissue,urine,saliva" uncertain uncertain original research 22847185 DNA methylation based biomarkers: practical considerations and applications. 976 mRNA diagnostic biomarker NETO2 human uncertain "renal cancer,lung cancer" H original research 22830255 Increase in NETO2 gene expression is a potential molecular genetic marker in renal and lung cancers. 977 mRNA diagnostic biomarker REG4 human tissue gastrointestinal cancer H original research 22826614 Significance of regenerating islet-derived type IV gene expression in gastroenterological cancers. 978 mRNA diagnostic biomarker NPTX2 human tissue pancreatic cancer L original research 22806544 Neuronal pentraxin II (NPTX2) is frequently down-regulated by promoter hypermethylation in pancreatic cancers. 979 mRNA diagnostic biomarker CDKL1 human tissue breast cancer H original research 22804458 Evaluation of cyclin-dependent kinase-like 1 expression in breast cancer tissues and its regulation in cancer cell growth. 980 mRNA diagnostic biomarker SMAD4 human tissue hepatocellular cancer L original research 22799322 Smad4 expression in hepatocellular carcinoma differs by hepatitis status. 981 mRNA diagnostic biomarker NDRG1 human uncertain glioma glioblastoma L original research 22787578 Inhibition of N-Myc down regulated gene 1 in in vitro cultured human glioblastoma cells. 982 mRNA diagnostic biomarker "AURK8,BIRC5" human uncertain colorectal cancer H original research 22783401 Nuclear Aurora B and cytoplasmic Survivin expression is involved in lymph node metastasis of colorectal cancer. 983 mRNA diagnostic biomarker NCAM1 human blood lung cancer non-small cell lung cancer H original research 22782455 Increased expression and function of P-glycoprotein in peripheral blood CD56+ cells is associated with the chemoresistance of non-small-cell lung cancer. 984 mRNA diagnostic biomarker NUTM1 human uncertain midline carcinoma uncertain original research 22777717 Clinicopathological significance of NUT rearrangements in poorly differentiated malignant tumors of the upper respiratory tract. 985 mRNA diagnostic biomarker HES1 human uncertain gastric cancer gastrointestinal stromal tumor L original research 22764137 Anti-tumor effects of the Notch pathway in gastrointestinal stromal tumors. 986 mRNA diagnostic biomarker "TFRC,MET,VEGFA" human tissue uncertain H original research 22761861 A minimal connected network of transcription factors regulated in human tumors and its application to the quest for universal cancer biomarkers. 987 mRNA diagnostic biomarker BTG3 human tissue oral cancer oral squamous cell carcinoma H(ISG15) original research 22740306 Gene expression changes in initiation and progression of oral squamous cell carcinomas revealed by laser microdissection and oligonucleotide microarray analysis. 988 mRNA diagnostic biomarker SOX10 human uncertain melanoma sinonasal mucosal melanoma H review 22736149 Expression of Sox10 and c-kit in sinonasal mucosal melanomas arising in the Chinese population. 989 mRNA diagnostic biomarker "PDGFA,PDGFRA" human "tissue,serum" cholangio cancer H original research 22733151 Platelet-derived growth factor may be a potential diagnostic and prognostic marker for cholangiocarcinoma. 990 mRNA diagnostic biomarker FASL844 human uncertain breast cancer uncertain original research 22732091 FASL-844 T/C polymorphism: a biomarker of good prognosis of breast cancer in the Tunisian population. 991 mRNA diagnostic biomarker ZNF217 human tissue breast cancer H original research 22728437 The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression. 992 mRNA diagnostic biomarker "EML4,ALK" human tissue lung cancer non-small cell lung cancer H original research 22722791 A novel mass spectrometry-based assay for diagnosis of EML4-ALK-positive non-small cell lung cancer. 993 mRNA diagnostic biomarker PTGS2 mice "tissue,serum" colorectal cancer H(Cox-2) original research 22710400 The establishment of supramolecular immunobead real-time PCR and the identification of Cox-2 as a metastasis-related marker in colorectal carcinoma. 994 mRNA diagnostic biomarker HRAS human tissue bladder cancer uncertain original research 22707223 Methylation pattern of oncogene HRAS gene promoter region and its clinical relevance to urocystic tumorigenesis 995 mRNA diagnostic biomarker KRAS human uncertain colorectal cancer H original research 22696308 Expression profiling shows differential molecular pathways and provides potential new diagnostic biomarkers for colorectal serrated adenocarcinoma. 996 mRNA diagnostic biomarker "PCA3,ERG" human tissue prostate cancer H original research 22674214 Rational basis for the combination of PCA3 and TMPRSS2:ERG gene fusion for prostate cancer diagnosis. 997 mRNA diagnostic biomarker PRMT6 human uncertain breast cancer H original research 22673335 Protein arginine methyltransferase 6-dependent gene expression and splicing: association with breast cancer outcomes. 998 mRNA diagnostic biomarker IGFBP3 human uncertain gastric cancer H original research 22664961 Putative tumor metastasis-associated genes in human gastric cancer. 999 mRNA diagnostic biomarker "MAGE,TAB1,AFP" human blood hepatocellular cancer H original research 22653756 MAGE-4 gene m-RNA and TGF in blood as potential biochemical markers for HCC in HCV-infected patients. 1000 mRNA diagnostic biomarker "combine(VHL,SERPINB5,S100P,IMP3)" human tissue pancreatic cancer pancreatic ductal adenocarcinoma uncertain original research 22646265 "Reevaluation and identification of the best immunohistochemical panel (pVHL, Maspin, S100P, IMP-3) for ductal adenocarcinoma of the pancreas." 1001 mRNA diagnostic biomarker JMJD6 human tissue breast cancer H original research 22621393 JMJD6 is a driver of cellular proliferation and motility and a marker of poor prognosis in breast cancer. 1002 mRNA diagnostic biomarker "AGR2,LGR5" human blood colorectal cancer H original research 22605983 Evaluation of the adenocarcinoma-associated gene AGR2 and the intestinal stem cell marker LGR5 as biomarkers in colorectal cancer. 1003 mRNA diagnostic biomarker NF1 human tissue neurofibroma neurofibromatosis type 1 uncertain original research 22593502 "Vascular wall cells contribute to tumourigenesis in cutaneous neurofibromas of patients with neurofibromatosis type 1. A comparative histological, ultrastructural and immunohistochemical study." 1004 mRNA diagnostic biomarker "RB1CC1,RECQL,DNMT3L" human uncertain uncertain H original research 22568098 Application of novel clinicopathological biomarkers. 1005 mRNA diagnostic biomarker TFF3 human "tissue,blood" thyroid cancer L original research 22568094 Aspiration biopsy-nucleic acid diagnosis for widely used preparative testing. 1006 mRNA diagnostic biomarker TNFRSF21 human serum sarcoma H(DR6) original research 22567163 DR6 as a diagnostic and predictive biomarker in adult sarcoma. 1007 mRNA diagnostic biomarker SPARC human tissue hepatocellular cancer L original research 22563191 Aberrant methylation of SPARC in human hepatocellular carcinoma and its clinical implication. 1008 mRNA diagnostic biomarker MIF human tissue renal cancer clear cell renal carcinoma H original research 22543583 Tumor-derived macrophage migration inhibitory factor promotes an autocrine loop that enhances renal cell carcinoma. 1009 mRNA diagnostic biomarker "GOLPH2,GP73,GOLM1" human "tissue,plasma " hepatocellular cancer H original research 22542941 Cloning and characterization of human Golgi phosphoprotein 2 gene (GOLPH2/GP73/GOLM1) promoter. 1010 mRNA diagnostic biomarker MKI67 human uncertain breast cancer H original research 22537114 Immunohistochemical Ki67 labeling index has similar proliferation predictive power to various gene signatures in breast cancer. 1011 mRNA diagnostic biomarker RUNX2 human "tissue,blood" thyroid cancer H original research 22511796 "Runx2 mRNA expression in the tissue, serum, and circulating non-hematopoietic cells of patients with thyroid cancer." 1012 mRNA diagnostic biomarker PTOV1 human uncertain prostate cancer H original research 22507319 Is there a role for prostate tumour overexpressed-1 in the diagnosis of HGPIN and of prostatic adenocarcinoma? A comparison with alpha-methylacyl CoA racemase. 1013 mRNA diagnostic biomarker KLK human uncertain "prostate cancer,breast cancer,ovarian cancer" uncertain review 22505514 "Kallikrein-related peptidases in prostate, breast, and ovarian cancers: from pathobiology to clinical relevance." 1014 mRNA diagnostic biomarker PLXNA2 human urine bladder cancer transitional cell bladder cancer H original research 22503047 Bradeion (SEPT4) as a urinary marker of transitional cell bladder cancer: a real-time polymerase chain reaction study of gene expression. 1015 mRNA diagnostic biomarker PTPRF human "tissue,plasma" prostate cancer H original research 22494190 Integrative analysis of N-linked human glycoproteomic data sets reveals PTPRF ectodomain as a novel plasma biomarker candidate for prostate cancer. 1016 mRNA diagnostic biomarker NKX3-1 human uncertain prostate cancer L original research 22465996 Nkx3.1 functions as para-transcription factor to regulate gene expression and cell proliferation in non-cell autonomous manner. 1017 mRNA diagnostic biomarker HERG1 human tissue head and neck cancer H original research 22460808 Role of HERG1 potassium channel in both malignant transformation and disease progression in head and neck carcinomas. 1018 mRNA diagnostic biomarker KLK11 human tissue laryngeal cancer L original research 22429520 Diagnostic and prognostic significance of human kallikrein 11 (KLK11) mRNA expression levels in patients with laryngeal cancer. 1019 mRNA diagnostic biomarker "BRAF,NRAS" human tissue melanoma H original research 22406360 Identification of biomarkers to distinguish clear cell sarcoma from malignant melanoma. 1020 mRNA diagnostic biomarker "PRRT2,RRBP1,KIT,PDGFRA" human tissue extragastrointestinal stromal cancer uncertain original research 22399613 Diagnostic relevance of overexpressions of PKC-θ and DOG-1 and KIT/PDGFRA gene mutations in extragastrointestinal stromal tumors: a Korean six-centers study of 28 cases. 1021 mRNA diagnostic biomarker "ETV6,NTRK3,IFS,CMN" human uncertain uncertain "L(ETV6,NTRK3)" original research 22374738 Mediators of receptor tyrosine kinase activation in infantile fibrosarcoma: a Children's Oncology Group study. 1022 mRNA diagnostic biomarker CAV1 human tissue breast cancer L original research 22370882 Immunohistochemical and molecular analysis of caveolin-1 expression in canine mammary tumors. 1023 mRNA diagnostic biomarker RRAD human plasma breast cancer H original research 22367215 Concordant release of glycolysis proteins into the plasma preceding a diagnosis of ER+ breast cancer. 1024 mRNA diagnostic biomarker MKI67 human tissue breast cancer H original research 22362219 Clinical relevance of Ki67 gene expression analysis using formalin-fixed paraffin-embedded breast cancer specimens. 1025 mRNA diagnostic biomarker EGFR human uncertain head and neck cancer head and neck squamous cell carcinoma H original research 22351687 Tumor epidermal growth factor receptor and EGFR PY1068 are independent prognostic indicators for head and neck squamous cell carcinoma. 1026 mRNA diagnostic biomarker SEL1L human tissue colorectal cancer H original research 22350780 "SEL1L, an UPR response protein, a potential marker of colonic cell transformation." 1027 mRNA diagnostic biomarker CDKN2A human "tissue,blood" ovarian cancer uncertain original research 22344043 p16 gene alterations in human ovarian cancers: comparison between tissue and blood samples. 1028 mRNA diagnostic biomarker MKP1 human tissue breast cancer L original research 22333693 The mitogen-activated protein kinase phosphatase-1 (MKP-1) gene is a potential methylation biomarker for malignancy of breast cancer. 1029 mRNA diagnostic biomarker U2AF1 human uncertain leukaemia uncertain original research 22323480 "Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis." 1030 mRNA diagnostic biomarker S100A4 human tissue osteosarcoma L original research 22292654 Knockdown of S100A4 decreases tumorigenesis and metastasis in osteosarcoma cells by repression of matrix metalloproteinase-9. 1031 mRNA diagnostic biomarker "ITGB3,ITGAV" human uncertain oral cancer oral squamous cell carcinoma uncertain original research 22271436 Single-nucleotide polymorphisms of integrins are associated with the risk and lymph node metastasis of oral squamous cell carcinoma. 1032 mRNA diagnostic biomarker TYMS human uncertain gallbladder cancer L original research 22270332 Role of thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expressions in gallbladder carcinoma. 1033 mRNA diagnostic biomarker "CEACAM5,CK,CD133" human uncertain colorectal cancer L original research 22267181 Prognostic significance of CTCs and CSCs of tumor drainage vein blood in Dukes' stage B and C colorectal cancer patients. 1034 mRNA diagnostic biomarker PRAME human uncertain mesothelioma H original research 22261449 PRAME (preferentially expressed antigen of melanoma) is a novel marker for differentiating serous carcinoma from malignant mesothelioma. 1035 mRNA diagnostic biomarker RAB25 human uncertain mesothelioma H original research 22249560 Rab25 is overexpressed in Müllerian serous carcinoma compared to malignant mesothelioma. 1036 mRNA diagnostic biomarker YY1 human uncertain uncertain uncertain review 22248055 The novel role of Yin Yang 1 in the regulation of epithelial to mesenchymal transition in cancer via the dysregulated NF-κB/Snail/YY1/RKIP/PTEN Circuitry. 1037 mRNA diagnostic biomarker SETD2 human "tissue,serum" hepatocellular cancer H original research 22224081 Expression characteristics of hypoxia-inducible factor-1α and its clinical values in diagnosis and prognosis of hepatocellular carcinoma. 1038 mRNA diagnostic biomarker EDNRB human tissue renal cancer clear-cell renal cell carcinoma L original research 22213152 "CD31, EDNRB and TSPAN7 are promising prognostic markers in clear-cell renal cell carcinoma revealed by genome-wide expression analyses of primary tumors and metastases." 1039 mRNA diagnostic biomarker TWIST2 human tissue head and neck cancer head and neck squamous cell cancer H original research 22201613 Overexpression of TWIST2 correlates with poor prognosis in head and neck squamous cell carcinomas. 1040 mRNA diagnostic biomarker "KAT5,HDAC1,KDM4A,SUV39H1,KDM6A,KAT2B" human tissue breast cancer uncertain original research 22199269 Histone-modifier gene expression profiles are associated with pathological and clinical outcomes in human breast cancer. 1041 mRNA diagnostic biomarker IL32 human "tissue,serum" hepatocellular cancer H original research 22198481 Dysregulation of overexpressed IL-32α in hepatocellular carcinoma suppresses cell growth and induces apoptosis through inactivation of NF-κB and Bcl-2. 1042 mRNA diagnostic biomarker MARP human uncertain uncertain uncertain review 22185618 Muscle ankyrin repeat proteins: their role in striated muscle function in health and disease. 1043 mRNA diagnostic biomarker LGALS1 human tissue oral cancer oral squamous cell cancer H original research 22177353 Expression of galectin-1 in carcinogenesis of oral mucosal epithelium. 1044 mRNA diagnostic biomarker TBX3 human uncertain head and neck cancer head and neck squamous cell cancer H original research 22154512 Transcriptional profiling identifies upregulated genes following induction of epithelial-mesenchymal transition in squamous carcinoma cells. 1045 mRNA diagnostic biomarker DPYD human uncertain cholangio cancer intrahepatic cholangio cancer L original research 22143355 Role of thymidylate synthase and dihydropyrimidine dehydrogenase mRNA in intrahepatic cholangiocarcinoma. 1046 mRNA diagnostic biomarker NSUN2 human tissue uncertain H original research 22136356 Frequent increased gene copy number and high protein expression of tRNA (cytosine-5-)-methyltransferase (NSUN2) in human cancers. 1047 mRNA diagnostic biomarker DOK2 human tissue gastric cancer H original research 22130622 DOK2 as a marker of poor prognosis of patients with gastric adenocarcinoma after curative resection. 1048 mRNA diagnostic biomarker WFDC2 human serum ovarian cancer H original research 22117965 The role of HE4 in ovarian cancer: inhibiting tumour cell proliferation and metastasis. 1049 mRNA diagnostic biomarker PCLAF human tissue adrenal cancer H original research 22096502 "KIAA0101 is overexpressed, and promotes growth and invasion in adrenal cancer." 1050 mRNA diagnostic biomarker KIT human tissue adenoid cystic cancer salivary adenoid cystic carcinoma H original research 22077630 Reappraisal of KIT mutation in adenoid cystic carcinomas of the salivary gland. 1051 mRNA diagnostic biomarker CTSE mice uncertain pancreatic cancer pancreatic ductal adenocarcinoma H original research 22068166 Detection of pancreatic cancer tumours and precursor lesions by cathepsin E activity in mouse models. 1052 mRNA diagnostic biomarker BIRC5 human tissue breast cancer H original research 22055399 Total Survivin and acetylated Survivin correlate with distinct molecular subtypes of breast cancer. 1053 mRNA diagnostic biomarker MASR human tissue colon cancer colon adenocarcinoma H original research 22048948 Characterization and significance of ACE2 and Mas receptor in human colon adenocarcinoma. 1054 mRNA diagnostic biomarker BIRC5 human tissue thyroid cancer H original research 22044815 Survivin-deltaEx3: a novel biomarker for diagnosis of papillary thyroid carcinoma. 1055 mRNA diagnostic biomarker TP53 human uncertain "renal cancer,breast cancer" H original research 21989411 Wildtype p53-specific antibody and T-cell responses in cancer patients. 1056 mRNA diagnostic biomarker SETD2 human uncertain renal cancer H original research 21959062 Role of mitogen-activated protein kinase (MAPK) in the sporadic renal cell carcinoma. 1057 mRNA diagnostic biomarker S100P human uncertain uncertain H review 21947242 Calcium-binding protein S100P and cancer: mechanisms and clinical relevance. 1058 mRNA diagnostic biomarker SETD2 human tissue upper aerodigestive tract carcinoma H original research 21945343 A high HIF-1α expression genotype is associated with poor prognosis of upper aerodigestive tract carcinoma patients. 1059 mRNA diagnostic biomarker HIWI human tissue colorectal cancer H original research 21933617 HIWI expression profile in cancer cells and its prognostic value for patients with colorectal cancer. 1060 mRNA diagnostic biomarker CDKN2A human tissue breast cancer H original research 21920875 p16(INK4a) expression and breast cancer risk in women with atypical hyperplasia. 1061 mRNA diagnostic biomarker KCNH1 human tissue cervical cancer H original research 21887469 Eag1 potassium channels as markers of cervical dysplasia. 1062 mRNA diagnostic biomarker "FANCC,PTCH1" human uncertain head and neck cancer L original research 21861228 Association of FANCC and PTCH1 with the development of early dysplastic lesions of the head and neck 1063 mRNA diagnostic biomarker GPC3 human uncertain hepatocellular cancer H original research 21847365 Suppression of glypican 3 inhibits growth of hepatocellular carcinoma cells through up-regulation of TGF-β2. 1064 mRNA diagnostic biomarker KIT human uncertain uncertain H original research 21835435 Absence of gene mutations in KIT-positive carcinoma showing thymus-like elements of the thyroid. 1065 mRNA diagnostic biomarker CDKN2A human tissue cervical cancer cervical squamous cell carcinoma H original research 21819702 Identification of high-risk human papillomavirus (hrHPV)-associated genes in early stage cervical squamous cell carcinomas. 1066 mRNA diagnostic biomarker TFG human tissue prostate cancer H original research 21809350 Identification of phosphorylated proteins involved in the oncogenesis of prostate cancer via Pin1-proteomic analysis. 1067 mRNA diagnostic biomarker BCL2 human tissue colorectal cancer L original research 21809033 Correlation between the expression of the BAG-1 gene and clinicopathologic factors in colorectal cancer. 1068 mRNA diagnostic biomarker SLC5A8 human tissue prostate cancer H original research 21802122 Protein expressions and genetic variations of SLC5A8 in prostate cancer risk and aggressiveness. 1069 mRNA diagnostic biomarker EN1 human uncertain adenoid cystic cancer H original research 21800291 Developmental transcription factor EN1--a novel biomarker in human salivary gland adenoid cystic carcinoma. 1070 mRNA diagnostic biomarker REIC human serum gastric cancer L original research 21796842 The secreted level of REIC protein in gastric carcinoma and its role of proliferation inhibition. 1071 mRNA diagnostic biomarker TP53 human uncertain medulloblastoma H original research 21796446 p53 expression predicts dismal outcome for medulloblastoma patients with metastatic disease. 1072 mRNA diagnostic biomarker TRPS-1 human tissue breast cancer H original research 21761336 Expression and relevance of TRPS-1: a new GATA transcription factor in breast cancer. 1073 mRNA diagnostic biomarker "ANO1,WT1" human tissue gastrointestinal cancer negative gastrointestinal stromal tumor uncertain original research 21756824 Clinicopathologic features and immunophenotypes of CD117-negative gastrointestinal stromal tumor. 1074 mRNA diagnostic biomarker OPCML human tissue ovarian cancer H original research 21755835 A study of the methylation status of opioid binding protein/cell adhesion molecule-like gene in ovarian cancer using nested methylation-specific polymerase chain reaction detection. 1075 mRNA diagnostic biomarker MTDH human tissue gallbladder cancer H original research 21750868 Astrocyte elevated gene-1 overexpression in human primary gallbladder carcinomas: an unfavorable and independent prognostic factor. 1076 mRNA diagnostic biomarker "SLC22A3,TWIST1" human tissue esophageal cancer esophageal squamous cell cancer H(TWIST1) original research 21732143 Twist1 is an independent prognostic factor of esophageal squamous cell carcinoma and associated with its epithelial-mesenchymal transition. 1077 mRNA diagnostic biomarker COL6A3 human tissue pancreatic cancer H original research 21719059 Tumor-specific expression and alternative splicing of the COL6A3 gene in pancreatic cancer. 1078 mRNA diagnostic biomarker HRPT2 human tissue thyroid cancer parathyroid carcinoma L original research 21717519 Parafibromin immunohistochemical staining to differentiate parathyroid carcinoma from parathyroid adenoma. 1079 mRNA diagnostic biomarker NDRG1 human "tissue,plasma" osteosarcoma H original research 21706236 Plasma membrane proteomic analysis of human osteosarcoma and osteoblastic cells: revealing NDRG1 as a marker for osteosarcoma. 1080 mRNA diagnostic biomarker NDRG2 human tissue astrocytoma L original research 21705028 Expression and prognostic value of NDRG2 in human astrocytomas. 1081 mRNA diagnostic biomarker PNKD human tissue ovarian cancer H(MR-1) original research 21702971 Myofibrillogenesis regulator 1 (MR-1) is a novel biomarker and potential therapeutic target for human ovarian cancer. 1082 mRNA diagnostic biomarker "combine(EGFRSISH,KRAS)" human uncertain colorectal cancer H original research 21694725 EGFR gene copy number assessment from areas with highest EGFR expression predicts response to anti-EGFR therapy in colorectal cancer. 1083 mRNA diagnostic biomarker CKS1B human tissue bladder cancer H(Cks2) original research 21672358 Cyclin-dependent kinase-associated protein Cks2 is associated with bladder cancer progression. 1084 mRNA diagnostic biomarker "ZIC1,KLOTHO" human tissue colorectal cancer L original research 21671493 DNA methylation of ZIC1 and KLOTHO gene promoters in colorectal carcinomas and its clinicopathological significance. 1085 mRNA diagnostic biomarker GPC3 human serum hepatocellular cancer H original research 21669573 Oncofetal antigen glypican-3 as a promising early diagnostic marker for hepatocellular carcinoma. 1086 mRNA diagnostic biomarker MKI67 human serum breast cancer H original research 21655990 "Evidence for biological effects of metformin in operable breast cancer: a pre-operative, window-of-opportunity, randomized trial." 1087 mRNA diagnostic biomarker "BCR,ABL1,KIT,CD20" human uncertain uncertain H(KIT) review 21652149 Critical comments for roles of biomarkers in the diagnosis and treatment of cancer. 1088 mRNA diagnostic biomarker TP63 human tissue "breast cancer,colon cancer,lung cancer" H original research 21623385 Cytoplasmic p63 immunohistochemistry is a useful marker for muscle differentiation: an immunohistochemical and immunoelectron microscopic study. 1089 mRNA diagnostic biomarker KLK human tissue gastric cancer L original research 21618246 Identification and validation of Kallikrein-ralated peptidase 11 as a novel prognostic marker of gastric cancer based on immunohistochemistry. 1090 mRNA diagnostic biomarker CTNNB1 human tissue hepatocellular cancer H original research 21617877 β-catenin plays a key role in metastasis of human hepatocellular carcinoma. 1091 mRNA diagnostic biomarker UHRF1 human tissue bladder cancer H original research 21611839 UHRF1 is associated with tumor recurrence in non-muscle-invasive bladder cancer. 1092 mRNA diagnostic biomarker KLK13 human tissue lung cancer non-small cell lung cancer H original research 21596022 Epigenetic activation of human kallikrein 13 enhances malignancy of lung adenocarcinoma by promoting N-cadherin expression and laminin degradation. 1093 mRNA diagnostic biomarker MYB human tissue adenoid cystic cancer H original research 21572406 Analysis of MYB expression and MYB-NFIB gene fusions in adenoid cystic carcinoma and other salivary neoplasms. 1094 mRNA diagnostic biomarker "FUS,CREB3L2" human tissue fibromatose H original research 21536545 FUS-CREB3L2/L1-positive sarcomas show a specific gene expression profile with upregulation of CD24 and FOXL1. 1095 mRNA diagnostic biomarker RPH3AL human serum colorectal cancer H original research 21536019 Detection of autoantibodies against Rabphilin-3A-like protein as a potential biomarker in patient's sera of colorectal cancer. 1096 mRNA diagnostic biomarker GOLM1 human "tissue,serum" hepatocellular cancer primary hepatic carcinoma H original research 21517136 A study of diagnostic value of golgi protein GP73 and its genetic assay in primary hepatic carcinoma. 1097 mRNA diagnostic biomarker WIF1 human uncertain breast cancer H original research 21515334 Suppression of WIF-1 through promoter hypermethylation causes accelerated proliferation of the aryl hydrocarbon receptor (AHR) overexpressing MCF10AT1 breast cancer cells. 1098 mRNA diagnostic biomarker UBE2C human uncertain colorectal cancer H original research 21514426 Bortezomib stabilizes mitotic cyclins and prevents cell cycle progression via inhibition of UBE2C in colorectal carcinoma. 1099 mRNA diagnostic biomarker FXYD3 human tissue urothelial cancer H original research 21499437 FXYD3: A Promising Biomarker for Urothelial Carcinoma. 1100 mRNA diagnostic biomarker "TP53,MKI67" human uncertain cutaneous cancer H(TP53) original research 21495358 Cutaneous squamocellular carcinoma--immunohistochemical aspects. 1101 mRNA diagnostic biomarker "EGFR,HER1,ERBB1" human "tissue,serum" uncertain H(EGFR) original research 21491912 Identification of immunoreactive regions of homology between soluble epidermal growth factor receptor and α5-integrin. 1102 mRNA diagnostic biomarker CHMP4C human tissue ovarian cancer H original research 21475838 Genome-wide gene expression profiles of ovarian carcinoma: Identification of molecular targets for the treatment of ovarian carcinoma. 1103 mRNA diagnostic biomarker PTEN human uncertain adenoid cystic cancer L original research 21472313 Methylation status of the PTEN gene in adenoid cystic carcinoma cells. 1104 mRNA diagnostic biomarker WFDC2 human "tissue,serum" uterine cancer endometrial cancer H original research 21468050 Diagnostic and prognostic impact of serum HE4 detection in endometrial carcinoma patients. 1105 mRNA diagnostic biomarker EGFR human uncertain head and neck cancer head and neck squamous cell carcinoma H original research 21467228 "Relationship between epidermal growth factor receptor status, p16(INK4A), and outcome in head and neck squamous cell carcinoma." 1106 mRNA diagnostic biomarker NPEPPS human plasma prostate cancer L original research 21446007 Enzymatic activity of free-prostate-specific antigen (f-PSA) is not required for some of its physiological activities. 1107 mRNA diagnostic biomarker DLEC1 human "tissue,serum" "gastric cancer,colorectal cancer" gastric and colorectal adenocarcinoma L original research 21443130 Epigenetic inactivation of deleted in lung and esophageal cancer 1 gene by promoter methylation in gastric and colorectal adenocarcinoma. 1108 mRNA diagnostic biomarker PRRT2 human tissue uncertain H original research 21441608 Protein kinase Cε as a cancer marker and target for anticancer therapy. 1109 mRNA diagnostic biomarker "SETD2,SLC2A1" human tissue oral cancer oral squamous cell cancer H original research 21438910 Coexpression of hypoxia-inducible factor-1α and glucose transporter-1 is associated with poor prognosis in oral squamous cell carcinoma patients. 1110 mRNA diagnostic biomarker MUC4 human tissue fibromyxoid sarcoma H original research 21415703 MUC4 is a highly sensitive and specific marker for low-grade fibromyxoid sarcoma. 1111 mRNA diagnostic biomarker CASQ2 human tissue leiomyosarcoma H original research 21412072 Expression of subtype-specific group 1 leiomyosarcoma markers in a wide variety of sarcomas by gene expression analysis and immunohistochemistry. 1112 mRNA diagnostic biomarker GRP78 human tissue hepatocellular cancer uncertain original research 21410057 No association between the haplotypic block in the 3' UTR of GRP78 and risk of hepatocellular carcinoma. 1113 mRNA diagnostic biomarker "SYT1,SSX1,SSX2" human uncertain synovial sarcoma L original research 21385630 Secernin-1 as a novel prognostic biomarker candidate of synovial sarcoma revealed by proteomics. 1114 mRNA diagnostic biomarker CLDN18 human uncertain pancreatic cancer H original research 21381080 Transcriptional regulation of claudin-18 via specific protein kinase C signaling pathways and modification of DNA methylation in human pancreatic cancer cells. 1115 mRNA diagnostic biomarker S100A4 human plasma "colon cancer,rectal cancer,gastric cancer" H original research 21354054 "Diagnostic and prognostic value of metastasis inducer S100A4 transcripts in plasma of colon, rectal, and gastric cancer patients." 1116 mRNA diagnostic biomarker "NDC80,HEC1" human tissue breast cancer uncertain original research 21352579 "Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy." 1117 mRNA diagnostic biomarker TYMS human tissue rectal cancer L original research 21347782 Thymidylate synthase as a prognostic biomarker for locally advanced rectal cancer after multimodal treatment. 1118 mRNA diagnostic biomarker RINF human tissue breast cancer H original research 21325450 RINF (CXXC5) is overexpressed in solid tumors and is an unfavorable prognostic factor in breast cancer. 1119 mRNA diagnostic biomarker ETS human tissue colorectal cancer H original research 21318373 Analysis of select members of the E26 (ETS) transcription factors family in colorectal cancer. 1120 mRNA diagnostic biomarker SPP1 human tissue hepatocellular cancer H original research 21310450 Specific expression of osteopontin and S100A6 in hepatocellular carcinoma. 1121 mRNA diagnostic biomarker MT3 human uncertain urothelial cancer H original research 21303554 Differences in the epigenetic regulation of MT-3 gene expression between parental and Cd+2 or As+3 transformed human urothelial cells. 1122 mRNA diagnostic biomarker "ADHFE1,BOLL,SLC6A15,ADAMTS5,TFPI2,EYA4,NPY,TWIST1,LAMA1,GAS7,MAEL,SFT2D3" human uncertain colorectal cancer uncertain original research 21298349 Epigenomic analysis of aberrantly methylated genes in colorectal cancer identifies genes commonly affected by epigenetic alterations. 1123 mRNA diagnostic biomarker TRPV human plasma uncertain H review 21290335 TRPV channels in tumor growth and progression. 1124 mRNA diagnostic biomarker BCL2L1 human tissue colorectal cancer L original research 21277008 Prognostic significance of Bcl-xL gene expression in human colorectal cancer. 1125 mRNA diagnostic biomarker "KRT19,MUC1" human uncertain lung cancer non-small cell lung cancer H original research 21232220 Detection of mRNA expression of CK-19 and MUC1 gene for diagnosis of lymph node micrometastasis in NSCLC patients by reverse transcriptase-polymerase chain reaction. 1126 mRNA diagnostic biomarker NDRG1 human tissue breast cancer L original research 21221878 N-myc downstream-regulated gene 1 (NDRG1) a differentiation marker of human breast cancer. 1127 mRNA diagnostic biomarker RPPA human tissue uncertain uncertain review 21197262 Targeted therapies in cancer - challenges and chances offered by newly developed techniques for protein analysis in clinical tissues. 1128 mRNA diagnostic biomarker ERRFI1 human tissue thyroid cancer papillary thyroid cancer L original research 21190978 Mitogen-inducible gene-6 is a multifunctional adaptor protein with tumor suppressor-like activity in papillary thyroid cancer. 1129 mRNA diagnostic biomarker FIZ1 human uncertain myeloma myeloproliferative neoplasm H original research 21180092 JAK2-V617F mutation in patients with myeloproliferative neoplasms: association with FLT3-ITD mutation. 1130 mRNA diagnostic biomarker NGAL human plasma uncertain H original research 21172066 Serum neutrophil gelatinase-B associated lipocalin (NGAL) levels in Down's syndrome patients. 1131 mRNA diagnostic biomarker PDCD5 human tissue ovarian cancer epithelial ovarian carcinoma L original research 21165576 Clinical and prognostic significance of lost or decreased PDCD5 expression in human epithelial ovarian carcinomas. 1132 mRNA diagnostic biomarker "UBE2C,MCM2,MCM6,FEN1,TPX2" human tissue lung cancer non-small cell lung cancer H(TPX2) original research 21163870 A five-gene and corresponding protein signature for stage-I lung adenocarcinoma prognosis. 1133 mRNA diagnostic biomarker ZBTB7A human tissue lung cancer non-small cell lung cancer H original research 21129306 Expression and clinical significance of Pokemon in non-small cell lung cancer. 1134 mRNA diagnostic biomarker EGFR human uncertain lung cancer H review 21103615 Tumors in the lung--morphologic features and the challenge of integrating biomarker signatures into diagnostics. 1135 mRNA diagnostic biomarker PDXP human tissue cervical cancer uncertain original research 21076641 MOLECULAR MARKERS OF EARLY CERVICAL NEOPLASIA. 1136 mRNA diagnostic biomarker KLK14 human tissue breast cancer H original research 21057706 Quantitative expression analysis and study of the novel human kallikrein-related peptidase 14 gene (KLK14) in malignant and benign breast tissues. 1137 mRNA diagnostic biomarker "SEPTIN9,UGT1A1" human uncertain colorectal cancer uncertain review 21040359 Review of biomarkers in colorectal cancer 1138 mRNA diagnostic biomarker PCA3 human uncertain prostate cancer H original research 20970419 The diagnostic value of PCA3 gene-based analysis of urine sediments after digital rectal examination for prostate cancer in a Chinese population. 1139 mRNA diagnostic biomarker IGF2 human serum hepatocellular cancer H original research 20959664 Characteristics of hepatic igf-ii expression and monitored levels of circulating igf-ii mRNA in metastasis of hepatocellular carcinoma 1140 mRNA diagnostic biomarker PTPRG human blood leukaemia L original research 20959494 Protein tyrosine phosphatase receptor type {gamma} is a functional tumor suppressor gene specifically downregulated in chronic myeloid leukemia. 1141 mRNA diagnostic biomarker CHFR human tissue laryngeal cancer laryngeal squamous cell carcinoma L original research 20942233 Study of mRNA expression level and hypermethylation of CHFR promoter in the laryngeal squamous cell carcinoma tissue. 1142 mRNA diagnostic biomarker "TWIST1,KRT19,HMAM" human tissue breast cancer H(TWIST1) original research 20920982 "Disseminated tumor cells in bone marrow assessed by TWIST1, cytokeratin 19, and mammaglobin A mRNA predict clinical outcome in operable breast cancer patients." 1143 mRNA diagnostic biomarker "HTR,TERT,CKS2" human uncertain bladder cancer "H(TERT,CKS2),L(HTR)" original research 20920335 "Expression and biological-clinical significance of hTR, hTERT and CKS2 in washing fluids of patients with bladder cancer." 1144 mRNA diagnostic biomarker CD44 human uncertain lymphoma Hodgkin and non-Hodgkin lymphoma L original research 20920234 Epigenetic regulation of CD44 in Hodgkin and non-Hodgkin lymphoma. 1145 mRNA diagnostic biomarker SMARCB1 human uncertain embryonal cancer L review 20882288 Molecular diagnostics of CNS embryonal tumors. 1146 mRNA diagnostic biomarker WT1 human tissue melanoma H original research 20842234 WT-1 expression in a spectrum of melanocytic lesions: Implication for differential diagnosis. 1147 mRNA diagnostic biomarker "TTS,TTP,DPYD" human tissue lung cancer non-small-cell lung cancer H original research 20837458 "Low thymidylate synthase, thymidine phosphorylase, and dihydropyrimidine dehydrogenase mRNA expression correlate with prolonged survival in resected non-small-cell lung cancer." 1148 mRNA diagnostic biomarker LRG1 human "tissue,serum" ovarian cancer H original research 20831812 Leucine-rich alpha-2-glycoprotein-1 is upregulated in sera and tumors of ovarian cancer patients. 1149 mRNA diagnostic biomarker HMLH1 human uncertain colorectal cancer L original research 20815811 Aberrant methylation of hMLH1 and p16INK4a in Tunisian patients with sporadic colorectal adenocarcinoma. 1150 mRNA diagnostic biomarker KLK6 human tissue ovarian cancer H original research 20800559 "Genomicinstabilityandcopy-numberheterogeneityofchromosome19q,includingthekallikreinlocus,inovariancarcinomas." 1151 mRNA diagnostic biomarker MPNST human serum neurofibroma neurofibromatosis type 1 H original research 20739432 Gene expression analysis identifies potential biomarkers of neurofibromatosis type 1 including adrenomedullin. 1152 mRNA diagnostic biomarker WWOX human tissue gastric cancer L original research 20737170 Loss of WW domain-containing oxidoreductase expression in the progression and development of gastric carcinoma: clinical and histopathologic correlations. 1153 mRNA diagnostic biomarker MGMT human uncertain glioma L review 20725792 MGMT promoter methylation in malignant gliomas 1154 mRNA diagnostic biomarker ATP5A1 human uncertain colorectal cancer L original research 20709793 Gene dysregulations driven by somatic copy number aberrations-biological and clinical implications in colon tumors: a paper from the 2009 William Beaumont Hospital Symposium on Molecular Pathology. 1155 mRNA diagnostic biomarker CA9 human "tissue,blood" renal cancer clear cell renal cell carcinoma H original research 20709527 "Carbonic anhydrase 9 in clear cell renal cell carcinoma: a marker for diagnosis, prognosis and treatment." 1156 mRNA diagnostic biomarker HSPD1 human "tissue,serum" prostate cancer H(Hsp60) original research 20708221 Immunohistochemical expression of Hsp60 correlates with tumor progression and hormone resistance in prostate cancer. 1157 mRNA diagnostic biomarker AKR1B10 human uncertain lung cancer non-small-cell lung cancer H original research 20705797 Smoking-induced upregulation of AKR1B10 expression in the airway epithelium of healthy individuals. 1158 mRNA diagnostic biomarker RERG human uncertain breast cancer H original research 20697807 "RERG (Ras-like, oestrogen-regulated, growth-inhibitor) expression in breast cancer: a marker of ER-positive luminal-like subtype." 1159 mRNA diagnostic biomarker EPHb4 human tissue gastric cancer H original research 20686847 Over-expression of Ephb4 is associated with carcinogenesis of gastric cancer. 1160 mRNA diagnostic biomarker COX8A human tissue hepatocellular cancer H original research 20683644 Involvement of hepatopoietin Cn in the development of human hepatocellular carcinoma. 1161 mRNA diagnostic biomarker ASCL1 human tissue neuroblastoma H original research 20677557 Expression and clinicopathologic significance of human achaete-scute homolog 1 in pulmonary neuroendocrine tumors. 1162 mRNA diagnostic biomarker MGMT human tissue oral cancer oral squamous cell carcinoma L original research 20674887 Promoter hypermethylation and expression profile of MGMT and CDH1 genes in oral cavity cancer. 1163 mRNA diagnostic biomarker PCA3 human urine prostate cancer H original research 20672322 PSGR and PCA3 as biomarkers for the detection of prostate cancer in urine. 1164 mRNA diagnostic biomarker ADAMTS4 human uncertain Ewing sarcoma H original research 20664926 Expression of ADAMTS4 in Ewing's sarcoma. 1165 mRNA diagnostic biomarker ERBB2 human "tissue,serum" breast cancer H original research 20662264 Study of the measurement of serum extracellular domain of HER-2/neu protein with CLIA method. 1166 mRNA diagnostic biomarker CLDN4 human tissue uncertain H original research 20641748 The MICAD Research Team. In: Molecular Imaging and Contrast Agent Database (MICAD) Internet. Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013. 2007 Jun 28. 1167 mRNA diagnostic biomarker ENG human tissue breast cancer H(CD105) review 20641214 Cheng KT(1). In: Molecular Imaging and Contrast Agent Database (MICAD) Internet. Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013. 2006 Jul 04. 1168 mRNA diagnostic biomarker S100A6 human tissue thyroid cancer papillary thyroid carcinoma H original research 20629554 Proteomic study of thyroid tumors reveals frequent up-regulation of the Ca2+ -binding protein S100A6 in papillary thyroid carcinoma. 1169 mRNA diagnostic biomarker KRAS human uncertain uncertain H review 20617134 Clinical relevance of KRAS in human cancers 1170 mRNA diagnostic biomarker "CEACAM5,KRT20,CD133,PROM1,CEA" human uncertain colorectal cancer L original research 20616575 Predictive value of cancer stem-like cells and cancer-associated genetic markers for peritoneal recurrence of colorectal cancer in patients after curative surgery. 1171 mRNA diagnostic biomarker AKR1B10 human tissue colorectal cancer L original research 20586184 Downregulation of AKR1B10 gene expression in colorectal cancer. 1172 mRNA diagnostic biomarker "RAS,RAF" human tissue thyroid cancer papillary thyroid carcinoma uncertain original research 20564403 Genetic alterations in the RAS/RAF/mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signaling pathways in the follicular variant of papillary thyroid carcinoma. 1173 mRNA diagnostic biomarker HMGA2 human tissue angiomyxoma vulvovaginal aggressive angiomyxoma H original research 20551826 HMGA2 is a sensitive but not specific immunohistochemical marker of vulvovaginal aggressive angiomyxoma. 1174 mRNA diagnostic biomarker KLF6 human tissue glioma glioblastoma L original research 20545576 Increased expression of the oncogenic KLF6-SV1 transcript in human glioblastoma. 1175 mRNA diagnostic biomarker CBX7 human tissue colorectal cancer L original research 20542683 The loss of the CBX7 gene expression represents an adverse prognostic marker for survival of colon carcinoma patients. 1176 mRNA diagnostic biomarker "EGFR,MAPK" human tissue pancreatic cystic cancer H(EGFR) original research 20495538 Association of epidermal growth factor receptor and mitogen-activated protein kinase with cystic neoplasms of the pancreas. 1177 mRNA diagnostic biomarker "DYNLRB2,ERBB4,PTPN13,ULK2,DUSCDKN2A" human tissue breast cancer positive breast cancer H(CDKN2A) original research 20480226 Gene expression profiling of response to mTOR inhibitor everolimus in pre-operatively treated post-menopausal women with oestrogen receptor-positive breast cancer. 1178 mRNA diagnostic biomarker "BRCA1,MGMT,GSTP1" human serum breast cancer invasive ductal breast carcinoma L original research 20470789 Clinical significance of promoter hypermethylation of DNA repair genes in tumor and serum DNA in invasive ductal breast carcinoma patients. 1179 mRNA diagnostic biomarker SCGB3A2 mice uncertain lung cancer H original research 20466451 Secretoglobin 3A2/uteroglobin-related protein 1 is a novel marker for pulmonary carcinoma in mice and humans. 1180 mRNA diagnostic biomarker CDH1 human uncertain nasopharyngeal cancer L original research 20462505 A single nucleotide polymorphism in the E-cadherin gene promoter -160 C/A is associated with risk of nasopharyngeal cancer. 1181 mRNA diagnostic biomarker "DPPIV,DDR1" human uncertain renal cancer L original research 20459800 Expression and activity profiles of DPP IV/CD26 and NEP/CD10 glycoproteins in the human renal cancer are tumor-type dependent. 1182 mRNA diagnostic biomarker MAPK human uncertain uncertain H original research 20458363 Protein-protein interaction reveals synergistic discrimination of cancer phenotype. 1183 mRNA diagnostic biomarker ANGPTL5 human uncertain renal cancer clear cell renal cell carcinoma H original research 20454689 Determination of angptl4 mRNA as a diagnostic marker of primary and metastatic clear cell renal-cell carcinoma. 1184 mRNA diagnostic biomarker LGALS7 human uncertain adenoid cystic cancer H review 20451577 Identification and consequences of galectin-3 expression in pituitary tumors. 1185 mRNA diagnostic biomarker "ACTC1,HPN" human tissue "prostate cancer,lung cancer" uncertain original research 20441232 Discovering disease-specific biomarker genes for cancer diagnosis and prognosis. 1186 mRNA diagnostic biomarker HSP27 human serum renal cancer H review 20437403 Genomic and proteomic approaches to renal cell carcinoma. 1187 mRNA diagnostic biomarker "PRSS2,ELA3B" human tissue pancreatic cancer "H(PRSS2),L(ELA3B)" original research 20428826 Identification of pancreatic juice proteins as biomarkers of pancreatic cancer. 1188 mRNA diagnostic biomarker "MAGE,BAGE,GAGE" human tissue ovarian cancer "H(MAGE),L(BAGE,GAGE)" original research 20423514 "Expression of tumor-specific antigen MAGE, GAGE and BAGE in ovarian cancer tissues and cell lines." 1189 mRNA diagnostic biomarker NGX6 human tissue colorectal cancer L original research 20423473 NGX6 gene mediated by promoter methylation as a potential molecular marker in colorectal cancer. 1190 mRNA diagnostic biomarker CDKN2A human tissue gallbladder cancer H original research 20422865 Expression of p16 protein in gallbladder carcinoma and its precancerous conditions. 1191 mRNA diagnostic biomarker IGF2 human tissue breast cancer H original research 20422427 Regulation of IGF2 transcript and protein expression by altered methylation in breast cancer. 1192 mRNA diagnostic biomarker "VIM,CD34,CDH1" dog uncertain meningioma L(CDH1) original research 20403881 "Immunohistochemical detection of CD34, E-cadherin, claudin-1, glucose transporter 1, laminin, and protein gene product 9.5 in 28 canine and 8 feline meningiomas." 1193 mRNA diagnostic biomarker LGALS4 human tissue bladder cancer H(Galectin-3) original research 20401558 Galectin-3 expression is associated with bladder cancer progression and clinical outcome. 1194 mRNA diagnostic biomarker GAGE human tissue uncertain H original research 20400850 Rational drug design: a GAGE derived peptide kills tumor cells. 1195 mRNA diagnostic biomarker WDR20 human uncertain esophageal cancer L original research 20391126 Functional alterations in the glutathione S-transferase family associated with enhanced occurrence of esophageal carcinoma in China. 1196 mRNA diagnostic biomarker HAVCR1 human uncertain renal cancer renal epithelial neoplasm uncertain original research 20388397 Expression and clinical significance of kidney injury molecule-1 in renal epithelial neoplasms. 1197 mRNA diagnostic biomarker NDRG1 human tissue gastric cancer L original research 20388062 A novel molecular marker for early detection and evaluating prognosis of gastric cancer: N-myc downstream regulated gene-1 (NDRG1). 1198 mRNA diagnostic biomarker "SNP,SEPP1,GPX4,SELS" human uncertain colorectal cancer uncertain original research 20378690 Genetic variants in selenoprotein genes increase risk of colorectal cancer. 1199 mRNA diagnostic biomarker HIF1A human uncertain colorectal cancer H original research 20363910 HIF1A overexpression is associated with poor prognosis in a cohort of 731 colorectal cancers. 1200 mRNA diagnostic biomarker GAL human uncertain leukaemia H original research 20332322 MLL-rearranged B lymphoblastic leukemias selectively express the immunoregulatory carbohydrate-binding protein galectin-1. 1201 mRNA diagnostic biomarker "VEGFC,bFGF" human tissue thyroid cancer papillary thyroid carcinoma H original research 20306451 Assessment of biomarkers for clinical diagnosis of papillary thyroid carcinoma with distant metastasis. 1202 mRNA diagnostic biomarker TOP2A human tissue adrenocortical cancer uncertain original research 20305693 Meta-analysis of adrenocortical tumour genomics data: novel pathogenic pathways revealed. 1203 mRNA diagnostic biomarker HIGM1 human serum uncertain H original research 20301576 X-Linked Hyper IgM Syndrome. 1204 mRNA diagnostic biomarker ADAM17 human tissue gallbladder cancer H original research 20300969 ADAM-17 over-expression in gallbladder carcinoma correlates with poor prognosis of patients. 1205 mRNA diagnostic biomarker "TP53,MYC,MAD1MAX,E2F1" human uncertain thyroid cancer "H(TP53,MYC)" original research 20201372 "Development of a set of diagnostic test systems for analysis of expression of C-myc, mad1, max, p53, and E2F1 gene oncomarkers by the reverse transcription reaction-polymerase chain reaction alignment technique" 1206 mRNA diagnostic biomarker "EGFR,VEGF,TFIIB,TBP,RPB5" human uncertain hepatocellular cancer H(EGFR) original research 20182587 Molecular genetics of hepatocellular neoplasia. 1207 mRNA diagnostic biomarker WT1 mice serum mesothelioma pleural mesothelioma H original research 20175889 In vitro and in vivo characterization of highly purified human mesothelioma derived cells. 1208 mRNA diagnostic biomarker "TP53,SMAD4,KRAS,EGFR" human uncertain colorectal cancer "H(TP53,KRAS)" review 20161020 "Approaches to biomarkers in human colorectal cancer: looking back, to go forward." 1209 mRNA diagnostic biomarker ERG human urine prostate cancer H original research 20160063 Evaluation of the ETS-related gene mRNA in urine for the detection of prostate cancer. 1210 mRNA diagnostic biomarker HIG2 human plasma ovarian cancer epithelial ovarian cancer H original research 20134266 Differential expression of hypoxia-inducible protein 2 among different histological types of epithelial ovarian cancer and in clear cell adenocarcinomas. 1211 mRNA diagnostic biomarker WT1 human blood myeloma H original research 20132661 Expression of WT1 gene in multiple myeloma patients at diagnosis: is WT1 gene expression a useful marker in multiple myeloma? 1212 mRNA diagnostic biomarker ADAMTS16 human tissue esophageal cancer esophageal squamous cell cancer H original research 20128818 Serial analysis of gene expression of esophageal squamous cell carcinoma: ADAMTS16 is upregulated in esophageal squamous cell carcinoma. 1213 mRNA diagnostic biomarker KLK5 human uncertain prostate cancer H original research 20128692 KLK5 gene expression is severely upregulated in androgen-independent prostate cancer cells after treatment with the chemotherapeutic agents docetaxel and mitoxantrone. 1214 mRNA diagnostic biomarker PCA3 human tissue prostate cancer H original research 20114043 PCA3 gene expression in prostate cancer tissue in a Chinese population: quantification by real-time FQ-RT-PCR based on exon 3 of PCA3. 1215 mRNA diagnostic biomarker CDKN2A human uncertain tonsillar cancer H original research 20091864 p16(INK4a) overexpression predicts translational active human papillomavirus infection in tonsillar cancer. 1216 mRNA diagnostic biomarker PSCA human tissue bladder cancer H original research 20083643 Genetic variation in PSCA and bladder cancer susceptibility in a Chinese population. 1217 mRNA diagnostic biomarker SLC5A8 human uncertain uncertain H original research 20082847 Identification and characterization of the human SLC5A8 gene promoter. 1218 mRNA diagnostic biomarker SEMA5A human tissue pancreatic cancer H original research 20073063 "High gene expression of semaphorin 5A in pancreatic cancer is associated with tumor growth, invasion and metastasis." 1219 mRNA diagnostic biomarker PSF3 human tissue colon cancer H original research 20059967 PSF3 marks malignant colon cancer and has a role in cancer cell proliferation. 1220 mRNA diagnostic biomarker "CDKN2A,E2F1" human tissue lung cancer H(CDKN2A) original research 20039540 Expression of p14(ARF) and E2F-1 in lung cancer in Gejiu and Xuanwei regions of Yunnan Province. 1221 mRNA diagnostic biomarker EGFR human tissue esophageal cancer esophageal squamous cell carcinoma H original research 20036807 EGFR gene alterations as a prognostic biomarker in advanced esophageal squamous cell carcinoma. 1222 mRNA diagnostic biomarker ERBB2 human uncertain breast cancer H review 20027191 Molecular predictors of response to trastuzumab and lapatinib in breast cancer. 1223 mRNA diagnostic biomarker "TP53,TOP" human tissue gastric cancer gastric adenocarcinoma H original research 20021828 "Correlation between aneuploidy of chromosome 17, over-expression of TP53 and TOPIIalpha, and the clinicopathological features and diagnosis of gastric adenocarcinoma." 1224 mRNA diagnostic biomarker "CFDNA,TP53" human plasma uterine cancer endometrial cancer H original research 19960433 "Circulating free DNA, p53 antibody and mutations of KRAS gene in endometrial cancer." 1225 mRNA diagnostic biomarker ISG15 human tissue prostate cancer H original research 19956859 The ubiquitin-like molecule interferon-stimulated gene 15 is overexpressed in human prostate cancer. 1226 mRNA diagnostic biomarker SPINK5 human uncertain uncertain L original research 19934316 Global changes in processing of mRNA 3' untranslated regions characterize clinically distinct cancer subtypes. 1227 mRNA diagnostic biomarker PTEN human uncertain uterine cancer endometrial cancer L original research 19930726 "Altered PTEN expression; a diagnostic marker for differentiating normal, hyperplastic and neoplastic endometrium." 1228 mRNA diagnostic biomarker BRAF human tissue colorectal cancer uncertain original research 19908233 Clinicopathological and protein characterization of BRAF- and K-RAS-mutated colorectal cancer and implications for prognosis. 1229 mRNA diagnostic biomarker TYMS human tissue gastric cancer H original research 19898266 Evaluation of prognostic factors for the response to S-1 in patients with stage II or III advanced gastric cancer who underwent gastrectomy. 1230 mRNA diagnostic biomarker "CASP10,CDH16,CLGN,CRABP1,HMGB2,ALPL2,ADAMTS2,CABIN1,ALDH1A3,USP13,NR2F2,KRTHB5" human tissue thyroid cancer uncertain original research 19893615 Increasing the number of thyroid lesions classes in microarray analysis improves the relevance of diagnostic markers. 1231 mRNA diagnostic biomarker PIM1 human tissue liposarcoma adipocytic neoplasm H original research 19878356 PIM-1 kinase expression in adipocytic neoplasms: diagnostic and biological implications. 1232 mRNA diagnostic biomarker APRIL human "tissue,sputum" lung cancer non-small cell lung cancer H original research 19842833 A proliferation-inducing ligand: a new biomarker for non-small cell lung cancer. 1233 mRNA diagnostic biomarker SPAG9 human tissue thyroid cancer H original research 19820019 Sperm-associated antigen 9: a novel diagnostic marker for thyroid cancer. 1234 mRNA diagnostic biomarker MSMB human "tissue,serum" prostate cancer L original research 19790236 The potential value of microseminoprotein-beta as a prostate cancer biomarker and therapeutic target. 1235 mRNA diagnostic biomarker NBR1 human serum epithelioid sarcoma H original research 19756736 Serum CA 125 expression as a tumor marker for diagnosis and monitoring the clinical course of epithelioid sarcoma. 1236 mRNA diagnostic biomarker TNXA human tissue melanoma H original research 19738457 Tenascin-X is a novel diagnostic marker of malignant mesothelioma. 1237 mRNA diagnostic biomarker "EGR1,CYR61,ADAMTS1" human tissue gastric cancer H(EGR1) original research 19727222 Identification of biomarkers for early detection in gastric cancer and its clinical biological significance.. 1238 mRNA diagnostic biomarker EGFR human uncertain melanoma H original research 19708533 Epidermal growth factor receptor aberrations in malignant mesotheliomas. 1239 mRNA diagnostic biomarker HSP27 human tissue prostate cancer H original research 19707199 Hsp-27 expression at diagnosis predicts poor clinical outcome in prostate cancer independent of ETS-gene rearrangement. 1240 mRNA diagnostic biomarker "KLK6,KLK13" human tissue ovarian cancer epithelial ovarian carcinoma H original research 19707197 KLK6 and KLK13 predict tumor recurrence in epithelial ovarian carcinoma. 1241 mRNA diagnostic biomarker RCTs human uncertain renal cancer L original research 19680475 Gene expression profiling of chromophobe renal cell carcinomas and renal oncocytomas by Affymetrix GeneChip using pooled and individual tumours. 1242 mRNA diagnostic biomarker EGFR human uncertain lung cancer non-small cell lung cancer H review 19680292 "Overview of molecular testing in non-small-cell lung cancer: mutational analysis, gene copy number, protein expression and other biomarkers of EGFR for the prediction of response to tyrosine kinase inhibitors." 1243 mRNA diagnostic biomarker "TCIRG1,ATP6V0A4" human tissue lung cancer uncertain original research 19674850 Expression profiling of integrins in lung cancer cells. 1244 mRNA diagnostic biomarker GFAP human tissue mesenchymal cancer L original research 19668151 Glial fibrillary acidic protein in tumor types with cartilaginous differentiation. 1245 mRNA diagnostic biomarker HIF2 mice uncertain lung cancer non-small cell lung cancer H original research 19662677 HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice. 1246 mRNA diagnostic biomarker AMACR human uncertain prostate cancer uncertain review 19661347 New molecular biomarkers for the prognosis and management of prostate cancer--the post PSA era. 1247 mRNA diagnostic biomarker "PTEN,MMP9" human tissue glioma L(PTEN) original research 19657395 Gene expression analysis of an EGFR indirectly related pathway identified PTEN and MMP9 as reliable diagnostic markers for human glial tumor specimens. 1248 mRNA diagnostic biomarker "UBE2C,TPX2,MCM2,MCM6,FEN,SFN" human tissue lung cancer non-small cell lung cancer H(TPX2) original research 19638491 Identification of gene signatures and molecular markers for human lung cancer prognosis using an in vitro lung carcinogenesis system. 1249 mRNA diagnostic biomarker APC human plasma lung cancer uncertain original research 19622298 Methylation quantification of adenomatous polyposis coli (APC) gene promoter in plasma of lung cancer patients 1250 mRNA diagnostic biomarker HBME human tissue thyroid cancer H original research 19589279 Comparative analysis of protein expression in differentiated thyroid tumours: a multicentre study. 1251 mRNA diagnostic biomarker FABP7 human tissue melanoma cutaneous malignant melanoma L original research 19587692 Aberrant fatty acid-binding protein-7 gene expression in cutaneous malignant melanoma. 1252 mRNA diagnostic biomarker CLEC4D human plasma myeloma H original research 19580342 Nucleartopographyofthe1q21genomicregionandMcl-1proteinlevelsassociatedwithpathophysiologyofmultiplemyeloma. 1253 mRNA diagnostic biomarker WT1 human tissue astrocytoma H original research 19578047 High-grade astrocytomas show increased Nestin and Wilms's tumor gene (WT1) protein expression. 1254 mRNA diagnostic biomarker PRMT1 human plasma lung cancer non-small cell lung cancer H original research 19571624 Comparative quantification of plasma hnRNP B1 mRNA in non-small cell lung cancer patients by real-time PCR. 1255 mRNA diagnostic biomarker GPC3 human tissue hepatocellular cancer H review 19550373 Glypican-3: a novel diagnostic marker for hepatocellular carcinoma and more. 1256 mRNA diagnostic biomarker ECRG4 human tissue esophageal cancer L original research 19521989 "Expression of esophageal cancer related gene 4 (ECRG4), a novel tumor suppressor gene, in esophageal cancer and its inhibitory effect on the tumor growth in vitro and in vivo." 1257 mRNA diagnostic biomarker PLAUR human tissue thyroid cancer H original research 19480010 "Urokinase receptor, MMP-1 and MMP-9 are markers to differentiate prognosis, adenoma and carcinoma in thyroid malignancies." 1258 mRNA diagnostic biomarker BIRC5 human tissue bladder cancer L original research 19472128 Expression of survivin and its spliced variants in bladder tumors as a potential prognostic marker. 1259 mRNA diagnostic biomarker "EREG,PGR,ERBB2" human uncertain breast cancer H review 19472036 Gene and chromosomal alterations in sporadic breast cancer: correlation with histopathological features and implications for genesis and progression. 1260 mRNA diagnostic biomarker CD74 human tissue colorectal cancer uncertain original research 19462453 HLA-DR expression is associated with better prognosis in sporadic Australian clinicopathological Stage C colorectal cancers. 1261 mRNA diagnostic biomarker "ERBB2,NEU" human uncertain bladder cancer transitional cell bladder cancer H original research 19443884 Role of polysomy 17 in transitional cell carcinoma of the bladder: immunohistochemical study of HER2/neu expression and fish analysis of c-erbB-2 gene and chromosome 17. 1262 mRNA diagnostic biomarker TSPAN1 human tissue colorectal cancer H original research 19437569 TSPAN1 protein expression: a significant prognostic indicator for patients with colorectal adenocarcinoma. 1263 mRNA diagnostic biomarker THBS1 human "tissue,serum" melanoma pleural mesothelioma H original research 19432887 Malignant mesothelioma-associated antigens recognized by tumor-infiltrating B cells and the clinical significance of the antibody titers. 1264 mRNA diagnostic biomarker EGFR human uncertain lung cancer non-small cell lung cancer H original research 19430813 Epidermal growth factor receptor genomic variation in NSCLC patients receiving tyrosine kinase inhibitor therapy: a systematic review and meta-analysis. 1265 mRNA diagnostic biomarker PCA3 human serum prostate cancer H review 19424173 The use of PCA3 in the diagnosis of prostate cancer. 1266 mRNA diagnostic biomarker LGL2 human tissue gastric cancer gastric adenocarcinoma H original research 19407852 Cell polarity protein Lgl2 is lost or aberrantly localized in gastric dysplasia and adenocarcinoma: an immunohistochemical study. 1267 mRNA diagnostic biomarker KLK8 human uncertain ovarian cancer L review 19384429 Ovarian cancer biomarkers: a focus on genomic and proteomic findings. 1268 mRNA diagnostic biomarker PPIH human uncertain uncertain uncertain review 19383362 Report on EU-USA workshop: how systems biology can advance cancer research (27 October 2008). 1269 mRNA diagnostic biomarker DSG3 human uncertain lung cancer squamous cell carcinoma of the lung H original research 19342368 The role of desmoglein-3 in the diagnosis of squamous cell carcinoma of the lung. 1270 mRNA diagnostic biomarker RCAS1 human tissue uncertain H review 19337974 Receptor-binding cancer antigen expressed on SiSo cells (RCAS1): a novel biomarker in the diagnosis and prognosis of human neoplasia. 1271 mRNA diagnostic biomarker CEP55 human tissue lung cancer non-small cell lung cancer H(FLJ10540) original research 19337377 VEGFA upregulates FLJ10540 and modulates migration and invasion of lung cancer via PI3K/AKT pathway. 1272 mRNA diagnostic biomarker MKI67 human uncertain epithelioid sarcoma L(INI1) original research 19318800 INI1 and GLUT-1 expression in epithelioid sarcoma and its cutaneous neoplastic and nonneoplastic mimics. 1273 mRNA diagnostic biomarker OBP2A human uncertain head and neck cancer uncertain original research 19318473 Telomerase-specific virotheranostics for human head and neck cancer. 1274 mRNA diagnostic biomarker EGFR human "tissue,plasma" colorectal cancer H original research 19309232 Genetic analysis of KRAS mutation status in metastatic colorectal cancer patients. 1275 mRNA diagnostic biomarker KAI1 human tissue renal cancer L original research 19303095 Differential expression of KAI1 metastasis suppressor protein in renal cell tumor histological subtypes. 1276 mRNA diagnostic biomarker KLK5 human tissue prostate cancer H original research 19299547 Quantitative analysis of human kallikrein 5 (KLK5) expression in prostate needle biopsies: an independent cancer biomarker. 1277 mRNA diagnostic biomarker TTF1 human tissue lung cancer "non-small cell lung cancer,small cell lung cancer" uncertain original research 19287461 Desmocollin-3: a new marker of squamous differentiation in undifferentiated large-cell carcinoma of the lung. 1278 mRNA diagnostic biomarker SAGE human serum gastric cancer uncertain original research 19261089 Transcriptome dissection of gastric cancer: identification of novel diagnostic and therapeutic targets from pathology specimens. 1279 mRNA diagnostic biomarker "combine(MAGEA1,MAGEA3)" human blood hepatocellular cancer H original research 19260505 "Detection of MAGE-1, MAGE-3 and AFP mRNA as multimarker by real-time quantitative PCR assay: a possible predictor of hematogenous micrometastasis of hepatocellular carcinoma." 1280 mRNA diagnostic biomarker IL10 human "tisue,plasma,serum" esophageal cancer gastroesophageal cancer H original research 19244371 Cancer cachexia is associated with the IL10 -1082 gene promoter polymorphism in patients with gastroesophageal malignancy. 1281 mRNA diagnostic biomarker CLDN4 human tissue lung cancer "non-small cell lung cancer,small cell lung cancer" H original research 19231096 Diagnostic utility of expression of claudins in non-small cell lung cancer: different expression profiles in squamous cell carcinomas and adenocarcinomas. 1282 mRNA diagnostic biomarker EGFR human uncertain lung cancer "non-small cell lung cancer,small cell lung cancer" H original research 19227598 Molecular diagnostics of epidermal growth factor receptor in non-small cell lung cancer. 1283 mRNA diagnostic biomarker CLDN6 human tissue teratoid/rhabdoid cancer "atypical teratoid,rhabdoid tumors" H original research 19220299 Claudin 6 is a positive marker for atypical teratoid/rhabdoid tumors. 1284 mRNA diagnostic biomarker NPEPPS human tissue prostate cancer uncertain review 19210674 Prostate-specific antigen kinetics in localized and advanced prostate cancer. 1285 mRNA diagnostic biomarker KLK human tissue prostate cancer H original research 19190824 "Treatment of PC3 prostate cancer cells with mitoxantrone, etoposide, doxorubicin and carboplatin induces distinct alterations in the expression of kallikreins 5 and 11." 1286 mRNA diagnostic biomarker BIRC5 human uncertain bladder cancer H original research 19186007 "Differential expression of survivin and its splice variants, survivin-DeltaEx3 and survivin-2B, in bladder cancer." 1287 mRNA diagnostic biomarker TSPAN13 human tissue prostate cancer H original research 19148481 Gene expression profiling reveals overexpression of TSPAN13 in prostate cancer. 1288 mRNA diagnostic biomarker HOXA13 human tissue esophageal cancer esophageal squamous cell cancer H original research 19145497 [Up-regulation of HOXA13 in esophageal squamous cell carcinoma of stage IIa and its effect on the prognosis]. 1289 mRNA diagnostic biomarker "RBSP3,CTDSPL,NPRL2,G21,HYAL1,HYAL2" human uncertain lung cancer "non-small cell lung cancer,small cell lung cancer" L original research 19140316 "Down-regulation of RBSP3/CTDSPL, NPRL2/G21, RASSF1A, ITGA9, HYAL1 and HYAL2 genes in non-small cell lung cancer." 1290 mRNA diagnostic biomarker ECT2 human tissue "lung cancer,esophageal cancer" H original research 19118053 Involvement of epithelial cell transforming sequence-2 oncoantigen in lung and esophageal cancer progression. 1291 mRNA diagnostic biomarker "UCHL1,TCTP,TIMP2,TPI" human serum lung cancer H original research 19116456 Identification of potential lung cancer biomarkers using an in vitro carcinogenesis model. 1292 mRNA diagnostic biomarker SETD2 human serum prostate cancer H original research 19096962 HIF-1alpha mRNA gene expression levels in improved diagnosis of early stages of prostate cancer. 1293 mRNA diagnostic biomarker "CD30,ALK" human uncertain lymphoma H original research 19091487 Lymphohistiocytic anaplastic large cell lymphoma involving skin: a diagnostic challenge. 1294 mRNA diagnostic biomarker UCP human tissue esophageal cancer esophageal squamous cell cancer H original research 19083192 The predictive role of E2-EPF ubiquitin carrier protein in esophageal squamous cell carcinoma. 1295 mRNA diagnostic biomarker CDC37 human tissue lung cancer H original research 19082487 Profiling of transcripts and proteins modulated by K-ras oncogene in the lung tissues of K-ras transgenic mice by omics approaches. 1296 mRNA diagnostic biomarker NDRG1 human uncertain glioma glioblastoma H original research 19082468 Oxygen-dependent regulation of NDRG1 in human glioblastoma cells in vitro and in vivo. 1297 mRNA diagnostic biomarker GABRA3 human tissue lung cancer H original research 19048400 Gammaaminobutyric acid A receptor alpha 3 subunit is overexpressed in lung cancer. 1298 mRNA diagnostic biomarker GLV-1H68 human uncertain melanoma uncertain original research 19035444 Real-time intraoperative detection of melanoma lymph node metastases using recombinant vaccinia virus GLV-1h68 in an immunocompetent animal model. 1299 mRNA diagnostic biomarker IFITM1 human tissue colorectal cancer H original research 19033100 Detection of interferon-induced transmembrane-1 gene expression for clinical diagnosis of colorectal cancer. 1300 mRNA diagnostic biomarker "BRST,GCDFP,TP53" human tissue ovarian cancer H original research 19031954 Breast metastasis 56 months before the diagnosis of primary ovarian cancer: a case study. 1301 mRNA diagnostic biomarker RUNX3 human tissue oral cancer oral squamous cell carcinoma L original research 19015875 Frequent inactivation of RUNX3 by promoter hypermethylation and protein mislocalization in oral squamous cell carcinomas. 1302 mRNA diagnostic biomarker PTPL1 human tissue breast cancer L original research 19004008 Expression of the putative tumor suppressor gene PTPN13/PTPL1 is an independent prognostic marker for overall survival in breast cancer. 1303 mRNA diagnostic biomarker MAL human tissue gastric cancer L original research 19002170 MAL promoter hypermethylation as a novel prognostic marker in gastric cancer. 1304 mRNA diagnostic biomarker CORGS human tissue uncertain uncertain original research 18989396 Inferring pathway activity toward precise disease classification. 1305 mRNA diagnostic biomarker INI1 human tissue rhabdomyosarcoma L original research 18985520 "Rhabdoid tumour: a malignancy of early childhood with variable primary site, histology and clinical behaviour." 1306 mRNA diagnostic biomarker LRRC4 human tissue glioma L original research 18976507 Promoter hypermethylation-mediated inactivation of LRRC4 in gliomas. 1307 mRNA diagnostic biomarker "CDK4,BAX,NOTCH4,ISGF3G,TNF,VISA" human uncertain hepatocellular cancer "H(CDK4,BAX,NOTCH4),L(ISGF3G,TNF,VISA)" original research 18959789 Genetic profile of Egyptian hepatocellular-carcinoma associated with hepatitis C virus Genotype 4 by 15 K cDNA microarray: preliminary study. 1308 mRNA diagnostic biomarker "PNMA2,SPOCK1,SERPINA10,GRIA2,GPR112,OR51E1" human tissue neuroblastoma uncertain original research 18953328 Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas. 1309 mRNA diagnostic biomarker PCYT2 human tissue bladder cancer L(ET-1) original research 18945538 Expression of the endothelin axis in noninvasive and superficially invasive bladder cancer: relation to clinicopathologic and molecular prognostic parameters. 1310 mRNA diagnostic biomarker TTF1 human tissue lung cancer non-small cell lung cancer L original research 18932182 TTF1 expression in non-small cell lung carcinoma: association with TTF1 gene amplification and improved survival. 1311 mRNA diagnostic biomarker "YBX1,ERBB2" human tissue breast cancer H original research 18925950 Redefining prognostic factors for breast cancer: YB-1 is a stronger predictor of relapse and disease-specific survival than estrogen receptor or HER-2 across all tumor subtypes. 1312 mRNA diagnostic biomarker DLC1 human uncertain myeloma multiple myeloma L original research 18923442 DLC1 tumor suppressor gene inhibits migration and invasion of multiple myeloma cells through RhoA GTPase pathway. 1313 mRNA diagnostic biomarker "MYCN,MYC" human uncertain neuroblastoma H(MYC) original research 18851746 Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas. 1314 mRNA diagnostic biomarker BCL2 human tissue colon cancer L original research 18844453 Quantitative expression analysis and prognostic significance of the novel apoptosis-related gene BCL2L12 in colon cancer. 1315 mRNA diagnostic biomarker CDKN2A human uncertain cervical cancer H review 18842994 Human papillomavirus mRNA and p16 detection as biomarkers for the improved diagnosis of cervical neoplasia. 1316 mRNA diagnostic biomarker MDM2 human tissue liposarcoma inflammatory liposarcoma H original research 18836421 Detection of MDM2 gene amplification or protein expression distinguishes sclerosing mesenteritis and retroperitoneal fibrosis from inflammatory well-differentiated liposarcoma. 1317 mRNA diagnostic biomarker CDH1 human tissue gastric cancer L original research 18835621 Comparative analysis of protein expressions in primary and metastatic gastric carcinomas. 1318 mRNA diagnostic biomarker ERBB2 human tissue breast cancer H original research 18833823 Application of liquid-based preparation to fine needle aspiration cytology in breast cancer. 1319 mRNA diagnostic biomarker "KRT7,LCN2,TSTA3" human uncertain bladder cancer uncertain original research 18828023 Immunoscreening of urinary bladder cancer cDNA library and identification of potential tumor antigen. 1320 mRNA diagnostic biomarker "TSPAN1,MKI67,CD34" human tissue gastric cancer H original research 18822690 "Clinicopathological significance of overexpression of TSPAN1, Ki67 and CD34 in gastric carcinoma." 1321 mRNA diagnostic biomarker S100P human uncertain pancreatic cancer H original research 18818507 Differential diagnosis of pancreatic tumors by molecular analysis of clinical specimens. 1322 mRNA diagnostic biomarker "RBL2,E2F2,CDK6,CCNE1,MYC,HSILs,E2F1,E2F3,E2F5,CCND1,CDK2,CDKN1B,PCNA,POLA,TP53,E2F4,CDKN1A,CDKN2A,DHFR" human tissue cervical cancer squamous cervical cancer "H(TP53,MYC,CDKN2A)" original research 18813814 Deregulation of the G1/S phase transition in cancer and squamous intraepithelial lesions of the uterine cervix: a case control study. 1323 mRNA diagnostic biomarker NK4a human tissue breast cancer L original research 18807517 Correlation of p16/INK4a gene damages and protein expression in the tumor tissue of sporadic breast cancer. 1324 mRNA diagnostic biomarker TERT human tissue uncertain H original research 18795940 Quantitative analysis of hTERT mRNA levels in cells microdissected from cytological specimens. 1325 mRNA diagnostic biomarker BRD7 human tissue nasopharyngeal cancer H original research 18778484 Promoter methylation inhibits BRD7 expression in human nasopharyngeal carcinoma cells. 1326 mRNA diagnostic biomarker "APC1,CCND2,HIN1,RASSF1A,TWIST1" human tissue breast cancer breast ductal carcinoma L original research 18769130 Quantitative promoter hypermethylation profiles of ductal carcinoma in situ in North American and Korean women: Potential applications for diagnosis. 1327 mRNA diagnostic biomarker MMP1 human tissue oral cancer oral squamous cell carcinoma H original research 18753061 Expression of MMP1 mRNA in oral squamous cell carcinoma and paired normal tissues 1328 mRNA diagnostic biomarker SOX11 human tissue lymphoma H original research 18729857 The subcellular Sox11 distribution pattern identifies subsets of mantle cell lymphoma: correlation to overall survival. 1329 mRNA diagnostic biomarker MME human tissue pancreatic cancer uncertain original research 18708424 Revision 2: an immunohistochemical approach and evaluation of solid pseudopapillary tumour of the pancreas. 1330 mRNA diagnostic biomarker S100 human uncertain oral cancer oral squamous cell carcinoma L original research 18705642 Expression profile of the S100 gene family members in oral squamous cell carcinomas. 1331 mRNA diagnostic biomarker UBE2C human tissue astrocytoma uncertain original research 18666437 Analysis of UbcH10 expression represents a useful tool for the diagnosis and therapy of astrocytic tumors. 1332 mRNA diagnostic biomarker "PCSK2,CCND2" human tissue thyroid cancer H original research 18661512 Does the 3-gene diagnostic assay accurately distinguish benign from malignant thyroid neoplasms? 1333 mRNA diagnostic biomarker AQP9 human tissue astrocytoma H original research 18652774 Expression of the water channel protein aquaporin-9 in human astrocytic tumours: correlation with pathological grade. 1334 mRNA diagnostic biomarker PCA3 human tissue prostate cancer H original research 18640109 Combined analysis of multiple mRNA markers by RT-PCR assay for prostate cancer diagnosis. 1335 mRNA diagnostic biomarker ISG15 human tissue breast cancer H original research 18627608 The ubiquitin-like molecule interferon-stimulated gene 15 (ISG15) is a potential prognostic marker in human breast cancer. 1336 mRNA diagnostic biomarker LHCGR human uncertain testicular cancer unilateral testicular tumour L original research 18620332 Unilateral testicular tumour associated to congenital adrenal hyperplasia: Failure of specific tumoral molecular markers to discriminate between adrenal rest and leydigioma. 1337 mRNA diagnostic biomarker HDMP1 human uncertain lung cancer L original research 18598225 Role of DMP1 and its future in lung cancer diagnostics. 1338 mRNA diagnostic biomarker "PDGFA,FGF,HIF1A" human tissue pancreatic cancer pancreatic ductal adenocarcinoma H(HIF1a) original research 18592007 "High expression of HIF1a is a predictor of clinical outcome in patients with pancreatic ductal adenocarcinomas and correlated to PDGFA, VEGF, and bFGF." 1339 mRNA diagnostic biomarker PRAME human tissue leukaemia H original research 18587578 Aberrant hypomethylation of the cancer-testis antigen PRAME correlates with PRAME expression in acute myeloid leukemia. 1340 mRNA diagnostic biomarker "REG4,CLDN18" human uncertain gastrointestinal cancer gastrointestinal signet ring cell carcinoma uncertain original research 18580680 Immunohistochemical staining of Reg IV and claudin-18 is useful in the diagnosis of gastrointestinal signet ring cell carcinoma. 1341 mRNA diagnostic biomarker RGS4 human tissue thyroid cancer H original research 18575725 Genome-wide gene expression profiles of thyroid carcinoma: Identification of molecular targets for treatment of thyroid carcinoma. 1342 mRNA diagnostic biomarker PRND human tissue uncertain H original research 18565727 Expression patterns of Doppel gene in golden hamster: quantification using real-time RT-PCR. 1343 mRNA diagnostic biomarker TH "mice,hamster" blood neuroblastoma uncertain original research 18520032 Useful markers for detecting minimal residual disease in cases of neuroblastoma. 1344 mRNA diagnostic biomarker "IGF2,MIB1" human uncertain adrenocortical cancer H review 18515740 Molecular markers and the pathogenesis of adrenocortical cancer. 1345 mRNA diagnostic biomarker BPIFA1 human uncertain lung cancer non-small cell lung cancer H(LunX) original research 18513434 Diagnostic utility of LunX mRNA in peripheral blood and pleural fluid in patients with primary non-small cell lung cancer. 1346 mRNA diagnostic biomarker ID4 human tissue breast cancer L original research 18513385 Promoter methylation-associated loss of ID4 expression is a marker of tumour recurrence in human breast cancer. 1347 mRNA diagnostic biomarker REG4 mice tissue gastric cancer H original research 18505053 Overexpression of RegIV in peritoneal dissemination of gastric cancer and its potential as A novel marker for the detection of peritoneal micrometastasis. 1348 mRNA diagnostic biomarker HSP10 human tissue ovarian cancer serous ovarian carcinoma L original research 18500265 Immunohistochemical analysis of possible chemoresistance markers identified by micro-arrays on serous ovarian carcinomas. 1349 mRNA diagnostic biomarker CLDN4 human tissue cholangio cancer H original research 18490072 Identification of novel candidate tumour marker genes for intrahepatic cholangiocarcinoma. 1350 mRNA diagnostic biomarker ODAM human tissue uncertain H original research 18472969 Expression of odontogenic ameloblast-associated protein (ODAM) in dental and other epithelial neoplasms. 1351 mRNA diagnostic biomarker TSP50 human uncertain breast cancer H original research 18462069 Identification and characterization of the human testes-specific protease 50 gene promoter. 1352 mRNA diagnostic biomarker PDCD4 human uncertain lung cancer L original research 18457901 Pdcd4 protein and mRNA level alterations do not correlate in human lung tumors. 1353 mRNA diagnostic biomarker TYMS human uncertain lung cancer non-small cell lung cancer L original research 18442042 Thymidylate synthase in situ protein expression and survival in stage I nonsmall-cell lung cancer. 1354 mRNA diagnostic biomarker CD109 human tissue breast cancer basal-like breast carcinoma H original research 18429827 CD109 expression in basal-like breast carcinoma. 1355 mRNA diagnostic biomarker H2AFZ human uncertain breast cancer H original research 18414489 Genomic analysis of estrogen cascade reveals histone variant H2A.Z associated with breast cancer progression. 1356 mRNA diagnostic biomarker HMAM human blood breast cancer uncertain original research 18409061 Detection of human mammaglobin mRNA in serial peripheral blood samples from patients with non-metastatic breast cancer is not predictive of disease recurrence. 1357 mRNA diagnostic biomarker MGMT human tissue glioma glioblastoma L original research 18400046 Anti-O6-methylguanine-methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: observer variability and lack of association with patient survival impede its use as clinical biomarker. 1358 mRNA diagnostic biomarker "TFE3,ASPL,TFE3" human tissue soft part sarcoma alveolar soft part sarcoma uncertain original research 18382356 Alveolar soft part sarcoma: a bimarker diagnostic strategy using TFE3 immunoassay and ASPL-TFE3 fusion transcripts in paraffin-embedded tumor tissues. 1359 mRNA diagnostic biomarker ECM1 human tissue thyroid cancer H original research 18374945 ECM1 expression in thyroid tumors--a comparison of real-time RT-PCR and IHC. 1360 mRNA diagnostic biomarker FHIT human "tissue,plasma" esophageal cancer esophageal squamous cell cancer L original research 18365557 DNA methylation and loss of protein expression in esophageal squamous cell carcinogenesis of high-risk area. 1361 mRNA diagnostic biomarker TYMS human uncertain breast cancer H original research 18357371 Expression of rTSbeta as a 5-fluorouracil resistance marker in patients with primary breast cancer. 1362 mRNA diagnostic biomarker SFRP5 human tissue breast cancer L original research 18356147 Epigenetic inactivation of the secreted frizzled-related protein-5 (SFRP5) gene in human breast cancer is associated with unfavorable prognosis. 1363 mRNA diagnostic biomarker MAL human tissue colorectal cancer L original research 18346269 Hypermethylated MAL gene - a silent marker of early colon tumorigenesis. 1364 mRNA diagnostic biomarker RAD9A human tissue prostate cancer H original research 18316588 Rad9 has a functional role in human prostate carcinogenesis. 1365 mRNA diagnostic biomarker WDR19 human tissue prostate cancer H original research 18316561 "WDR19 expression is increased in prostate cancer compared with normal cells, but low-intensity expression in cancers is associated with shorter time to biochemical failures and local recurrence." 1366 mRNA diagnostic biomarker UPII human tissue bladder cancer L original research 18313120 Loss expression of uroplakin III is associated with clinicopathologic features of aggressive bladder cancer. 1367 mRNA diagnostic biomarker "TMS1,FAS,RPRM,GLIPR1" human uncertain prostate cancer L review 18310272 The emergence of DNA methylation as a key modulator of aberrant cell death in prostate cancer. 1368 mRNA diagnostic biomarker KRT19 human tissue thyroid cancer thyroid papillary carcinoma H original research 18308654 Expression of cytokeratin 19 in the diagnosis of thyroid papillary carcinoma by quantitative polymerase chain reaction. 1369 mRNA diagnostic biomarker GRAMD4 human tissue lung cancer non-small cell lung cancer uncertain original research 18302964 Molecular profiling of genes in squamous cell lung carcinoma in Asian Indians. 1370 mRNA diagnostic biomarker FOLH1 human uncertain prostate cancer uncertain review 18297820 Updated application of prostate-specific membrane antigen to the diagnosis and treatment of prostate cancer 1371 mRNA diagnostic biomarker ATM human tissue oral cancer H original research 18288488 ATM in oral carcinogenesis: association with clinicopathological features. 1372 mRNA diagnostic biomarker SBEM human tissue breast cancer H original research 18269587 Expression of small breast epithelial mucin (SBEM) protein in tissue microarrays (TMAs) of primary invasive breast cancers. 1373 mRNA diagnostic biomarker BMP7 human tissue colorectal cancer H original research 18259822 Clinical significance of BMP7 in human colorectal cancer. 1374 mRNA diagnostic biomarker EGFR human tissue lung cancer non-small cell lung cancer H original research 18258923 Epidermal growth factor receptor (EGFR) high gene copy number and activating mutations in lung adenocarcinomas are not consistently accompanied by positivity for EGFR protein by standard immunohistochemistry. 1375 mRNA diagnostic biomarker TERT human tissue renal cancer H original research 18250061 Expression of human telomerase reverse transcriptase in renal cell carcinoma and its clinical significance. 1376 mRNA diagnostic biomarker KLK6 "monkey,cattle,mouse,rat " serum ovarian cancer H original research 18243805 Identification and analysis of mammalian KLK6 orthologue genes for prediction of physiological substrates. 1377 mRNA diagnostic biomarker ERBB2 human tissue breast cancer H original research 18237248 The influence of serum HER-2 levels and HER-2 codon 655 polymorphism on breast cancer outcome. 1378 mRNA diagnostic biomarker WT1 human blood leukaemia H original research 18231915 "Cross-sectional monitoring of Wilms' tumor gene 1 (WT1) expression in Iranian patients with acute lymphoblastic leukemia at diagnosis, relapse and remission." 1379 mRNA diagnostic biomarker "PRRT2,CAP43,YBX1" human uncertain breast cancer L original research 18224398 Preclinical studies of molecular-targeting diagnostic and therapeutic strategies against breast cancer. 1380 mRNA diagnostic biomarker "CLDN18,ANXA8" human tissue pancreatic cancer pancreatic ductal adenocarcinoma H original research 18223320 New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8. 1381 mRNA diagnostic biomarker BPIFA1 human uncertain gastric cancer gastric hepatoid adenocarcinomaeven H original research 18204429 Gene expression profiling with microarray and SAGE identifies PLUNC as a marker for hepatoid adenocarcinoma of the stomach. 1382 mRNA diagnostic biomarker "TFF3,PLAB,TG,ADM3,HGD1,LGALS3" human tissue thyroid cancer uncertain original research 18198227 TFF3-based candidate gene discrimination of benign and malignant thyroid tumors in a region with borderline iodine deficiency. 1383 mRNA diagnostic biomarker TP63 human tissue giant cell cancer H original research 18192965 Gene expression profiling identifies p63 as a diagnostic marker for giant cell tumor of the bone. 1384 mRNA diagnostic biomarker FAM72A human uncertain nasopharyngeal cancer H original research 18180201 Association between EBNA2 and LMP1 subtypes of Epstein-Barr virus and nasopharyngeal carcinoma in Thais. 1385 mRNA diagnostic biomarker MMP11 human "tissue,serum" gastric cancer H original research 18172255 Identification of matrix metalloproteinase 11 as a predictive tumor marker in serum based on gene expression profiling. 1386 mRNA diagnostic biomarker EEF1A2 human tissue ovarian cancer H original research 18164751 The prognostic significance of elongation factor eEF1A2 in ovarian cancer. 1387 mRNA diagnostic biomarker CD44 human tissue adenocarcinoma uncertain original research 18091389 "Diagnostic utility of CD44 standard, CD44v6, and CD44v3-10 expression in adenocarcinomas presenting in serous fluids." 1388 mRNA diagnostic biomarker HSP90B1 rat tissue hepatocellular cancer H original research 18086628 Dynamic expression of rat heat shock protein gp96 and its gene during development of hepatocellular carcinoma. 1389 mRNA diagnostic biomarker LAMA4 human tissue hepatocellular cancer H original research 18084776 "LAMA4, highly expressed in human hepatocellular carcinoma from Chinese patients, is a novel marker of tumor invasion and metastasis." 1390 mRNA diagnostic biomarker KCNH1 human tissue esophageal cancer esophageal squamous cell cancer H original research 18080766 Expression and prognostic roles of Eag1 in resected esophageal squamous cell carcinomas. 1391 mRNA diagnostic biomarker EEA1 human tissue prostate cancer H original research 18077911 Expression of prostate cancer antigen-1 in prostate cancer and its clinical significance. 1392 mRNA diagnostic biomarker "KIT,PDGFR" human tissue uncertain H(KIT) original research 18064489 "Targeting c-KIT, PDGFR in cancer of unknown primary: a screening study for molecular markers of benefit." 1393 mRNA diagnostic biomarker PCA3 human uncertain prostate cancer H original research 18061575 "A multicenter evaluation of the PCA3 molecular urine test: pre-analytical effects, analytical performance, and diagnostic accuracy." 1394 mRNA diagnostic biomarker AMACR human uncertain prostate cancer uncertain original research 18059348 Mechanisms of Disease: biomarkers and molecular targets from microarray gene expression studies in prostate cancer. 1395 mRNA diagnostic biomarker "CXCL8,IL6" human uncertain melanoma H original research 18056965 GRO-alpha: a potential marker for cancer and aging silenced by RNA interference. 1396 mRNA diagnostic biomarker "STEAP1,CCND1,NKX2" human blood Ewing sarcoma uncertain original research 18056173 Novel markers of subclinical disease for Ewing family tumors from gene expression profiling. 1397 mRNA diagnostic biomarker TFF3 human serum thyroid cancer L review 18018560 Role of blood and nucleic acid testing in diagnosis of thyroid carcinoma. 1398 mRNA diagnostic biomarker ATM human tissue melanoma metastatic vertical growth phase melanoma H original research 18006941 Ataxia telangiectasia-mutated gene is a possible biomarker for discrimination of infiltrative deep penetrating nevi and metastatic vertical growth phase melanoma. 1399 mRNA diagnostic biomarker "CEACAM5,MMP,TIMP" human tissue colorectal cancer H original research 17992052 "Clinical relevance of the expression of mRNA of MMP-7, MMP-9, TIMP-1, TIMP-2 and CEA tissue samples from colorectal liver metastases." 1400 mRNA diagnostic biomarker JAG1 human uncertain breast cancer lymph node-negative breast cancer H original research 17990101 JAG1 expression is associated with a basal phenotype and recurrence in lymph node-negative breast cancer. 1401 mRNA diagnostic biomarker TAC1 human "tissue,plasma" esophageal cancer esophageal squamous cell cancer L original research 17975140 Hypermethylation of tachykinin-1 is a potential biomarker in human esophageal cancer. 1402 mRNA diagnostic biomarker HOXC10 human tissue cervical cancer cervical squamous cell carcinoma H original research 17974957 Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion. 1403 mRNA diagnostic biomarker MECP2 human uncertain cervical cancer uncertain review 17963416 Gene discovery in cervical cancer : towards diagnostic and therapeutic biomarkers. 1404 mRNA diagnostic biomarker HOXA7 human uncertain ovarian cancer epithelial ovarian cancer H original research 17959889 HOXA7 in epithelial ovarian cancer: interrelationships between differentiation and clinical features. 1405 mRNA diagnostic biomarker "PLAUR,RAB31" human tissue breast cancer H original research 17952591 Urokinase receptor splice variant uPAR-del4/5-associated gene expression in breast cancer: identification of rab31 as an independent prognostic factor. 1406 mRNA diagnostic biomarker HMGA2 human tissue thyroid cancer H original research 17943974 Upregulation of HMGA2 in thyroid carcinomas: a novel molecular marker to distinguish between benign and malignant follicular neoplasias. 1407 mRNA diagnostic biomarker HSPA9 human tissue hepatocellular cancer H original research 17934217 Association of mortalin (HSPA9) with liver cancer metastasis and prediction for early tumor recurrence. 1408 mRNA diagnostic biomarker UBE2C human tissue breast cancer H original research 17933517 UbcH10 is overexpressed in malignant breast carcinomas. 1409 mRNA diagnostic biomarker MALT human tissue lymphoma B-cell lymphoma uncertain original research 17922687 Amyloid deposition in primary pulmonary marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue. 1410 mRNA diagnostic biomarker "TSGA10,SYCP3" human tissue uncertain H(TSGA10) original research 17920210 "Expression of two testis-specific genes, TSGA10 and SYCP3, in different cancers regarding to their pathological features." 1411 mRNA diagnostic biomarker "HRPAP20,TIMELESS" human uncertain breast cancer L original research 17909269 Oligonucleotide microarray analysis of estrogen receptor alpha-positive postmenopausal breast carcinomas: identification of HRPAP20 and TIMELESS as outstanding candidate markers to predict the response to tamoxifen. 1412 mRNA diagnostic biomarker "ARNT2,GST" human tissue breast cancer L(ARNT2) original research 17899366 Drug metabolism-related genes as potential biomarkers: analysis of expression in normal and tumour breast tissue. 1413 mRNA diagnostic biomarker SERPINA9 human tissue lymphoma H(Gcet1) original research 17898315 "Gcet1 (centerin), a highly restricted marker for a subset of germinal center-derived lymphomas." 1414 mRNA diagnostic biomarker "SLC22A3,POU5F1" human tissue "seminoma,embryonal cancer" uncertain original research 17875493 Tumor risk in disorders of sex development (DSD). 1415 mRNA diagnostic biomarker HERG1 human tissue esophageal cancer esophageal squamous cell carcinomas H original research 17786970 Overexpression of hERG1 in resected esophageal squamous cell carcinomas: a marker for poor prognosis. 1416 mRNA diagnostic biomarker CEACAM5 human uncertain colorectal cancer H original research 17786336 Rapid genetic diagnosis with transcription-reverse transcription concerted reaction system for peritoneal recurrence and survival in colorectal cancer patients. 1417 mRNA diagnostic biomarker "MET,TWIST,APC" human uncertain osteosarcoma L original research 17786187 Involvement of MET/TWIST/APC combination or the potential role of ossification factors in pediatric high-grade osteosarcoma oncogenesis. 1418 mRNA diagnostic biomarker HSP90B1 human tissue oral cancer oral squamous cell carcinoma H(Grp94) original research 17726464 Network-based analysis of calcium-binding protein genes identifies Grp94 as a target in human oral carcinogenesis. 1419 mRNA diagnostic biomarker ANXA7 human tissue uncertain L original research 17708571 ANXA7 expression represents hormone-relevant tumor suppression in different cancers. 1420 mRNA diagnostic biomarker ERBB human tissue cholangio cancer extrahepatic cholangiocarcinoma H original research 17690040 Expression of c-erbB-2 proto-oncogene in extrahepatic cholangiocarcinoma and its clinical significance. 1421 mRNA diagnostic biomarker PLXNA2 human tissue "seminoma,embryonal cancer" H original research 17682839 Aberrant expression and distribution of the OCT-4 transcription factor in seminomas. 1422 mRNA diagnostic biomarker "IGFBP4,IGFBP5" human tissue breast cancer "H(IGFBP4),L(IGFBP5)" original research 17675285 Prognostic significance of insulin-like growth factor binding protein (IGFBP)-4 and IGFBP-5 expression in breast cancer. 1423 mRNA diagnostic biomarker TGFBI rat tissue hepatocellular cancer H original research 17669238 An evaluation of transforming growth factor-beta 1 in diagnosing hepatocellular carcinoma and metastasis. 1424 mRNA diagnostic biomarker WISP1 human tissue rectal cancer H original research 17657846 Overexpression of connective tissue growth factor WISP-1 in Chinese primary rectal cancer patients. 1425 mRNA diagnostic biomarker ITIH5 human tissue breast cancer L original research 17653090 The extracellular matrix protein ITIH5 is a novel prognostic marker in invasive node-negative breast cancer and its aberrant expression is caused by promoter hypermethylation. 1426 mRNA diagnostic biomarker EGFR human tissue lung cancer H original research 17643093 EGFR expression as an ancillary tool for diagnosing lung cancer in cytology specimens. 1427 mRNA diagnostic biomarker "EML4,ALK" human uncertain lung cancer non-small cell lung cancer uncertain original research 17625570 Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. 1428 mRNA diagnostic biomarker MROS human uncertain brain tumor H original research 17611638 Combination of high-resolution magic angle spinning proton magnetic resonance spectroscopy and microscale genomics to type brain tumor biopsies. 1429 mRNA diagnostic biomarker EFNB2 human tissue esophageal cancer esophageal squamous cell carcinoma H original research 17611172 Expression and prognostic significance of EFNB2 and EphB4 genes in patients with oesophageal squamous cell carcinoma. 1430 mRNA diagnostic biomarker GADD45 human uncertain upper gastrointestinal cancer H original research 17607914 Prediction of response to neoadjuvant chemotherapy in carcinomas of the upper gastrointestinal tract. 1431 mRNA diagnostic biomarker TSG101 human tissue ovarian cancer H original research 17606716 Up-regulation of tumor susceptibility gene 101 conveys poor prognosis through suppression of p21 expression in ovarian cancer. 1432 mRNA diagnostic biomarker "NBR1,WFDC2" human uncertain ovarian cancer epithelial ovarian cancer uncertain review 17583933 "Epithelial ovarian cancer: disease etiology, treatment, detection, and investigational gene, metabolite, and protein biomarkers." 1433 mRNA diagnostic biomarker PTGS2 human tissue cervical cancer uncertain original research 17578348 Hypermethylation of the COX-2 gene is a potential prognostic marker for cervical cancer. 1434 mRNA diagnostic biomarker NMPs human tissue renal cancer uncertain original research 17572229 Characterization of nuclear matrix protein alterations associated with renal cell carcinoma. 1435 mRNA diagnostic biomarker TMSB15A human uncertain prostate cancer H original research 17567946 Thymosin beta-NB is the human isoform of rat thymosin beta15. 1436 mRNA diagnostic biomarker SPA1 human tissue prostate cancer H original research 17549420 DNA methylation markers of surfactant proteins in lung cancer. 1437 mRNA diagnostic biomarker SNCG human tissue breast cancer H original research 17534899 Neuronal protein synuclein gamma predicts poor clinical outcome in breast cancer. 1438 mRNA diagnostic biomarker TSPY human tissue testicular cancer H original research 17521702 The Y-encoded TSPY protein: a significant marker potentially plays a role in the pathogenesis of testicular germ cell tumors. 1439 mRNA diagnostic biomarker OSMR human tissue cervical cancer cervical squamous cell carcinoma H original research 17516585 Gain and overexpression of the oncostatin M receptor occur frequently in cervical squamous cell carcinoma and are associated with adverse clinical outcome. 1440 mRNA diagnostic biomarker TUBB6 human uncertain cervical cancer cervical squamous cell carcinoma H original research 17503414 Overexpression of the alpha v beta 6 integrin in cervical squamous cell carcinoma is a prognostic factor for decreased survival. 1441 mRNA diagnostic biomarker CD109 human tissue "breast cancer,prostate cancer" H original research 17493171 "CD109, a new marker for myoepithelial cells of mammary, salivary, and lacrimal glands and prostate basal cells." 1442 mRNA diagnostic biomarker "NPM1,NCL" human uncertain uncertain H review 17484127 Functions of the histone chaperone nucleolin in diseases. 1443 mRNA diagnostic biomarker "GATA3,S100P" human "tissue,serum" urothelial cancer H original research 17460449 Placental S100 (S100P) and GATA3: markers for transitional epithelium and urothelial carcinoma discovered by complementary DNA microarray. 1444 mRNA diagnostic biomarker "ERBB2,NEU" human tissue uterine cancer uterine serous papillary carcinoma H original research 17451461 "HER-2/neu overexpression and amplification in uterine serous papillary carcinoma: comparative analysis of immunohistochemistry, real-time reverse transcription-polymerase chain reaction, and fluorescence in situ hybridization." 1445 mRNA diagnostic biomarker APC human uncertain colorectal cancer uncertain original research 17411426 Novel APC mutations in Czech and Slovak FAP families: clinical and genetic aspects. 1446 mRNA diagnostic biomarker PRIM1 human tissue hepatocellular cancer H original research 17393520 Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma. 1447 mRNA diagnostic biomarker "INT6,TID1" human tissue uncertain H original research 17385060 "Expression of EIF3-p48/INT6, TID1 and Patched in cancer, a profiling of multiple tumor types and correlation of expression." 1448 mRNA diagnostic biomarker "MST1,RANBP2,EIF4G1" "human,mice" tissue prostate cancer H original research 17372272 "Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate." 1449 mRNA diagnostic biomarker "VEGF,ENG" human "tissue,blood" gastric cancer H original research 17334712 Vascular endothelial growth factor and endoglin (CD-105) in gastric cancer. 1450 mRNA diagnostic biomarker FABP7 human "tissue,urine" renal cancer uncertain original research 17320655 Detection of transcript for brain-type fatty Acid-binding protein in tumor and urine of patients with renal cell carcinoma. 1451 mRNA diagnostic biomarker S100 human uncertain uncertain H original research 17300669 Nestin expression as a new marker in malignant peripheral nerve sheath tumors. 1452 mRNA diagnostic biomarker OLFM4 human tissue "colon,cancer,breast cancer,lung cancer" H original research 17270020 "Specific overexpression of OLFM4(GW112/HGC-1) mRNA in colon, breast and lung cancer tissues detected using quantitative analysis." 1453 mRNA diagnostic biomarker BRCA1 human uncertain breast cancer L original research 17244477 Alternative splicing of breast cancer associated gene BRCA1 from breast cancer cell line. 1454 mRNA diagnostic biomarker "PTTG1,BIRC5,UBE2C,TK1" human blood breast cancer H(PTTG1) original research 17220641 "Combination of multiple mRNA markers (PTTG1, Survivin, UbcH10 and TK1) in the diagnosis of Taiwanese patients with breast cancer by membrane array." 1455 mRNA diagnostic biomarker BCL2 human uncertain colorectal cancer L original research 17219742 "Immunohistochemical expression of bcl-2 in UICC stage I and III colorectal carcinoma patients: correlation with c-erbB-2, p53, ki-67, CD44, laminin and collagen IV in evaluating prognostic significance." 1456 mRNA diagnostic biomarker "combine(CD44,BMI1)" mice uncertain head and neck cancer head and neck squamous cell carcinoma H original research 17210912 Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. 1457 mRNA diagnostic biomarker PLIN2 human tissue renal cancer clear cell renal cell carcinoma H(ADFP) original research 17200350 Expression of adipose differentiation-related protein: a predictor of cancer-specific survival in clear cell renal carcinoma. 1458 mRNA diagnostic biomarker FXYD6 human tissue synovial sarcoma H original research 17197923 Dysadherin expression as a significant prognostic factor and as a determinant of histologic features in synovial sarcoma: special reference to its inverse relationship with E-cadherin expression. 1459 mRNA diagnostic biomarker UCHL1 dog tissue lymphoma canine epitheliotropic T-cell lymphoma uncertain original research 17197626 Immunohistochemical detection of protein gene product 9.5 (PGP 9.5) in canine epitheliotropic T-cell lymphoma (mycosis fungoides). 1460 mRNA diagnostic biomarker MGB1 human tissue breast cancer H original research 17192791 Breast-specific expression of MGB1/mammaglobin: an examination of 480 tumors from various organs and clinicopathological analysis of MGB1-positive breast cancers. 1461 mRNA diagnostic biomarker GKN1 human tissue gastric cancer gastic adenocarcinoma L original research 17187689 Proteomic alteration in gastic adenocarcinomas from Japanese patients. 1462 mRNA diagnostic biomarker "TYMS,DPYD" human tissue colorectal cancer H(TYMS) original research 17179731 "Predictive role of thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer patients receiving adjuvant 5-fluorouracil." 1463 mRNA diagnostic biomarker "PSGR,PMEPA1" human blood prostate cancer H original research 17166409 Prostate--specific G protein couple receptor genes and STAG1/PMEPA1 in peripheral blood from patients with prostatic cancer. 1464 mRNA diagnostic biomarker FHIT human tissue cervical cancer H original research 17152494 Expression of FHIT genes in CIN and cervical carcinoma and the relationship between FHIT gene and p53 and HPV16/18. 1465 mRNA diagnostic biomarker SPP1 human "tissue,plasma" gastric cancer H original research 17148500 "Elevated plasma osteopontin associated with gastric cancer development, invasion and survival." 1466 mRNA diagnostic biomarker SLIT2 dog tissue melanoma canine malignant mammary tumor H original research 17146174 Expression patterns of the slit subfamily mRNA in canine malignant mammary tumors. 1467 mRNA diagnostic biomarker MRTFA human tissue renal cancer uncertain original research 17145811 Gene expression profiling separates chromophobe renal cell carcinoma from oncocytoma and identifies vesicular transport and cell junction proteins as differentially expressed genes. 1468 mRNA diagnostic biomarker "VCA,EBNA1" human serum nasopharyngeal cancer uncertain original research 17129209 Expression of VCA (viral capsid antigen) and EBNA1 (Epstein-Barr-virus-encoded nuclear antigen 1) genes of Epstein-Barr virus in Pichia pastoris and application of the products in a screening test for patients with nasopharyngeal carcinoma. 1469 mRNA diagnostic biomarker GPC3 human tissue testicular cancer H original research 17122513 Glypican 3: a novel marker in testicular germ cell tumors. 1470 mRNA diagnostic biomarker TERT human "tissue,plasma" prostate cancer H original research 17108213 Real-time quantification of human telomerase reverse transcriptase mRNA in the plasma of patients with prostate cancer. 1471 mRNA diagnostic biomarker ADAM8 human tissue prostate cancer L original research 17106710 ADAM8 expression in prostate cancer is associated with parameters of unfavorable prognosis. 1472 mRNA diagnostic biomarker LY6K human tissue breast cancer H original research 17089039 LY-6K gene: a novel molecular marker for human breast cancer. 1473 mRNA diagnostic biomarker "MAP3K14,AFP" human "tissue,blood" hepatocellular cancer L(AFP) original research 17085339 Combined serum hepatoma-specific alpha-fetoprotein and circulating alpha-fetoprotein-mRNA in diagnosis of hepatocellular carcinoma. 1474 mRNA diagnostic biomarker "PCSK2,PLAB" human uncertain thyroid cancer follicular thyroid cancer L(TGmRNA) original research 17075775 Cytology and mRNA expression analysis of fine needle aspirates of thyroid nodules in an East German region with borderline iodine deficiency. 1475 mRNA diagnostic biomarker SLN human uncertain breast cancer uncertain original research 17071045 Correlation between molecular metastases in sentinel lymph nodes of breast cancer patients and St Gallen risk category. 1476 mRNA diagnostic biomarker "IGFBP3,CCNE1,FOLR1P1,RAB25,MUC4,EDN1,CD24,kallikreins,claudins,NOTCH3,MMP" human uncertain "melanoma,ovarian cancer" uncertain original research 17062665 Gene expression signatures differentiate ovarian/peritoneal serous carcinoma from diffuse malignant peritoneal mesothelioma 1477 mRNA diagnostic biomarker NAF1 human tissue leukaemia H original research 17016622 Multiple splicing variants of Naf1/ABIN-1 transcripts and their alterations in hematopoietic tumors. 1478 mRNA diagnostic biomarker UBE2C human uncertain ovarian cancer H original research 17016443 UbcH10 expression may be a useful tool in the prognosis of ovarian carcinomas. 1479 mRNA diagnostic biomarker "CASP9,FGR,TP73,HSPG2,ERCC1,FRAP1,EPHA2,IL12A,E2F5,TNFRSF10B,TNFRSF10A,EFNB3,BCL2" human tissue breast cancer sporadic breast cancer L(BCL2) original research 17011986 Genetic expression profiles and chromosomal alterations in sporadic breast cancer in Mexican women. 1480 mRNA diagnostic biomarker ECA39 human tissue colorectal cancer H original research 17007058 ECA39 is a novel distant metastasis-related biomarker in colorectal cancer. 1481 mRNA diagnostic biomarker YY1 human tissue osteosarcoma H original research 16962318 Expression of transcription factor Yin Yang 1 in human osteosarcomas. 1482 mRNA diagnostic biomarker "ST2,RPL21" human uncertain osteosarcoma H original research 16944589 [Changes of nuclear matrix proteins during differentiation of human osteosarcoma MG-63 cells induced by HMBA]. 1483 mRNA diagnostic biomarker KLK10 human tissue "colorectal cancer,gastric cancer" H original research 16928223 Clinical significance of human kallikrein 10 gene expression in colorectal cancer and gastric cancer. 1484 mRNA diagnostic biomarker DUSP26 human uncertain thyroid cancer H original research 16924234 "A novel amplification target, DUSP26, promotes anaplastic thyroid cancer cell growth by inhibiting p38 MAPK activity." 1485 mRNA diagnostic biomarker "PCA3,EZH2,TRPM8" human uncertain prostate cancer H(PCA3) original research 16921506 Quantitative multi-gene expression profiling of primary prostate cancer. 1486 mRNA diagnostic biomarker SERPINB5 human tissue renal cancer uncertain original research 16918974 Nuclear maspin detection in renal cell tumours: possible diagnostic role and correlation with p53 status. 1487 mRNA diagnostic biomarker KIT human tissue stromal tumor H original research 16892012 PKCtheta expression in gastrointestinal stromal tumor. 1488 mRNA diagnostic biomarker "TSC1,TSC2" human uncertain cardiac rhabdomyoma uncertain original research 16877242 Novel mutation in the TSC2 gene associated with prenatally diagnosed cardiac rhabdomyomas and cerebral tuberous sclerosis. 1489 mRNA diagnostic biomarker "NRG1,ERBB3" human tissue sarcoma H original research 16867224 Constitutive activation of neuregulin/ERBB3 signaling pathway in clear cell sarcoma of soft tissue. 1490 mRNA diagnostic biomarker MT3 human tissue urothelial cancer H original research 16854967 Enhanced expression of metallothionein isoform 3 protein in tumor heterotransplants derived from As+3- and Cd+2-transformed human urothelial cells. 1491 mRNA diagnostic biomarker "TMS1,PYCARD" human tissue prostate cancer L original research 16848908 Methylation mediated silencing of TMS1/ASC gene in prostate cancer. 1492 mRNA diagnostic biomarker SNCG human tissue breast cancer H original research 16821081 Expression of neuronal protein synuclein gamma gene as a novel marker for breast cancer prognosis. 1493 mRNA diagnostic biomarker KLK10 human uncertain ovarian cancer L original research 16800732 "Human kallikrein 10, a predictive marker for breast cancer." 1494 mRNA diagnostic biomarker MYCN human uncertain neuroblastoma H original research 16778177 Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number. 1495 mRNA diagnostic biomarker LYPD4 human uncertain adenocarcinoma uncertain original research 16776998 Expression and diagnostic application of C4.4A protein in squamous cell carcinoma and adenocarcinoma. 1496 mRNA diagnostic biomarker IL6 human serum breast cancer H original research 16773437 "Interleukin-6, multidrug resistance protein-1 expression and response to paclitaxel in women with metastatic breast cancer: results of cancer and leukemia group B trial 159806." 1497 mRNA diagnostic biomarker GPC3 human "tissue,serum" hepatocellular cancer H original research 16772080 Significance of glypican-3 mRNA expression in hepatocellular carcinoma tissues and peripheral blood cells. 1498 mRNA diagnostic biomarker TPO human "tissue,serum" thyroid cancer thyroid papillary carcinoma H original research 16756464 Quantitation of thyroid peroxidase mRNA in peripheral blood for early detection of thyroid papillary carcinoma. 1499 mRNA diagnostic biomarker HMGA1 human uncertain prostate cancer uncertain original research 16752910 Acetylation and phosphorylation of high-mobility group A1 proteins in PC-3 human tumor cells. 1500 mRNA diagnostic biomarker XLSTAT human blood bladder cancer uncertain original research 16740760 Novel blood biomarkers of human urinary bladder cancer. 1501 mRNA diagnostic biomarker "HMLH1,CDKN2A,MGMT" human tissue "ovarian cancer,uterine cancer" endometrial cancer "H(HMLH1,CDKN2A),L(MGMT)" original research 16740754 The high frequency of de novo promoter methylation in synchronous primary endometrial and ovarian carcinomas. 1502 mRNA diagnostic biomarker "LRMP,LRMP" human tissue lymphoma H original research 16739114 "Jaw1/LRMP, a germinal centre-associated marker for the immunohistological study of B-cell lymphomas." 1503 mRNA diagnostic biomarker "LCN2,PLAT" human tissue pancreatic cancer H original research 16733850 Identification of biomarkers of human pancreatic adenocarcinomas by expression profiling and validation with gene expression analysis in endoscopic ultrasound-guided fine needle aspiration samples. 1504 mRNA diagnostic biomarker TP63 human tissue nasopharyngeal cancer H original research 16729897 The expression of p63 is associated with the differential stage in nasopharyngeal carcinoma and EBV infection. 1505 mRNA diagnostic biomarker BIN1 human tissue pancreatic cancer pancreatic endocrine tumour H original research 16728581 Gene expression profiles of progressive pancreatic endocrine tumours and their liver metastases reveal potential novel markers and therapeutic targets. 1506 mRNA diagnostic biomarker PIN1 human tissue cervical cancer H original research 16711024 Expression of Pin1 and Ki67 in cervical cancer and their significance. 1507 mRNA diagnostic biomarker UPII human tissue urothelial cancer uncertain original research 16691580 Prospective evaluation of the prognostic relevance of molecular staging for urothelial carcinoma. 1508 mRNA diagnostic biomarker SERPINB3 human serum squamous cell cancer H original research 16681421 Molecular detection of squamous cell carcinoma antigen transcripts in peripheral blood of cancer patients. 1509 mRNA diagnostic biomarker "HSPD1,JUN,TOPORSLP" human uncertain adrenocortical cancer "H(HSPD1,TOPORSLP),L(JUN)" original research 16677799 Gene expression profiling of adrenal cortical tumors by cDNA macroarray analysis. Results of a preliminary study. 1510 mRNA diagnostic biomarker "HOXB7,ASPH" human tissue cholangio cancer uncertain original research 16673309 Detection of human aspartyl (asparaginyl) beta-hydroxylase and homeobox B7 mRNA in brush cytology specimens from patients with bile duct cancer. 1511 mRNA diagnostic biomarker SARP2 human tissue pancreatic cancer uncertain original research 16670620 Aberrant methylation of secreted apoptosis-related protein 2 (SARP2) in pure pancreatic juice in diagnosis of pancreatic neoplasms. 1512 mRNA diagnostic biomarker TRIM21 human serum esophageal cancer esophageal squamous cell carcinoma H original research 16630135 Presence of serum tripartite motif-containing 21 antibodies in patients with esophageal squamous cell carcinoma. 1513 mRNA diagnostic biomarker KLK7 human tissue breast cancer H original research 16627559 Quantitative reverse transcription-PCR assay for detection of mRNA encoding full-length human tissue kallikrein 7: prognostic relevance of KLK7 mRNA expression in breast cancer. 1514 mRNA diagnostic biomarker MAGEA1 human uncertain head and neck cancer H original research 16619566 Expression of MAGE A 1-6 mRNA in sputa of head and neck cancer patients--a preliminary report. 1515 mRNA diagnostic biomarker WNT human tissue bladder cancer H original research 16609023 Combination analysis of hypermethylated Wnt-antagonist family genes as a novel epigenetic biomarker panel for bladder cancer detection. 1516 mRNA diagnostic biomarker RPL19 human tissue prostate cancer H original research 16609016 Ribosomal protein l19 is a prognostic marker for human prostate cancer. 1517 mRNA diagnostic biomarker WFDC2 human tissue uncertain H(HE4) original research 16607372 Comprehensive analysis of HE4 expression in normal and malignant human tissues. 1518 mRNA diagnostic biomarker GALNT6 human uncertain breast cancer uncertain original research 16596643 UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (ppGalNAc-T6) mRNA as a potential new marker for detection of bone marrow-disseminated breast cancer cells. 1519 mRNA diagnostic biomarker WT1 human uncertain leukaemia H original research 16575000 High WT1 expression after induction therapy predicts high risk of relapse and death in pediatric acute myeloid leukemia. 1520 mRNA diagnostic biomarker PAGE1 human tissue uncertain H(CT) review 16548764 Cancer testis antigens--their importance in immunotherapy and in the early detection of cancer. 1521 mRNA diagnostic biomarker KLK8 human tissue ovarian cancer L original research 16533772 Human kallikrein 8 protein is a favorable prognostic marker in ovarian cancer. 1522 mRNA diagnostic biomarker BUB1 human tissue salivary cancer salivary gland cancer H original research 16525682 Correlation of human Bub1 expression with tumor-proliferating activity in salivary gland tumors. 1523 mRNA diagnostic biomarker TP53 human "tissue,serum" breast cancer H original research 16525651 Mutant p53 protein in serum could be used as a molecular marker in human breast cancer. 1524 mRNA diagnostic biomarker P504S human uncertain ovarian cancer uncertain original research 16512597 Immunohistochemistry as a diagnostic aid in the evaluation of ovarian tumors. 1525 mRNA diagnostic biomarker "KRT7,KRT20,GCDFP15,BRST2,S100,CLTA,MOC31,MART1" human uncertain hepatocellular cancer uncertain original research 16508622 Pathology of liver metastases. 1526 mRNA diagnostic biomarker PDLIM4 human tissue prostate cancer L original research 16489065 PDLIM4 repression by hypermethylation as a potential biomarker for prostate cancer. 1527 mRNA diagnostic biomarker CD24 human tissue bladder cancer H original research 16488989 The metastasis-associated gene CD24 is regulated by Ral GTPase and is a mediator of cell proliferation and survival in human cancer. 1528 mRNA diagnostic biomarker FHL1 human uncertain uncertain L original research 16452211 SRC uses Cas to suppress Fhl1 in order to promote nonanchored growth and migration of tumor cells 1529 mRNA diagnostic biomarker BRAF human uncertain thyroid cancer uncertain review 16444351 Pathogenesis of differentiated thyroid cancer (papillary and follicular). 1530 mRNA diagnostic biomarker CK18 human "tissue,blood" gastric cancer H original research 16425429 Correlation between CK18 gene and gastric carcinoma micrometastasis. 1531 mRNA diagnostic biomarker CA9 human tissue cervical cancer H original research 16416108 Tumor-associated carbonic anhydrases are linked to metastases in primary cervical cancer. 1532 mRNA diagnostic biomarker "P21WAF1,MKI67" human tissue cervical cancer squamous cervical cancer H original research 16415998 "Relationship among HPV16 infection and Expression of hTERT, p21waf1, Ki67 in cervical intraepithelial neoplasias and squamous cell carcinomas of cervix uteri" 1533 mRNA diagnostic biomarker TWIST1 human tissue nasopharyngeal cancer H original research 16412561 The clinical significance of twist expression in nasopharyngeal carcinoma. 1534 mRNA diagnostic biomarker PRMT1 human tissue colorectal cancer H original research 16404425 Editing of hnRNP K protein mRNA in colorectal adenocarcinoma and surrounding mucosa. 1535 mRNA diagnostic biomarker "CEACAM5,KRT20" human blood colorectal cancer H original research 16391782 Usefulness and clinical significance of quantitative real-time RT-PCR to detect isolated tumor cells in the peripheral blood and tumor drainage blood of patients with colorectal cancer. 1536 mRNA diagnostic biomarker DRFS human tissue breast cancer H original research 16361546 Tumor gene expression and prognosis in breast cancer patients with 10 or more positive lymph nodes. 1537 mRNA diagnostic biomarker TXAS human tissue bladder cancer H original research 16357168 Prognostic and functional significance of thromboxane synthase gene overexpression in invasive bladder cancer. 1538 mRNA diagnostic biomarker FAM83A human tissue lung cancer H original research 16354590 "BJ-TSA-9, a novel human tumor-specific gene, has potential as a biomarker of lung cancer." 1539 mRNA diagnostic biomarker KCNJ13 human tissue cholangio cancer H original research 16330944 Identification of novel diagnostic markers for choroid plexus tumors: a microarray-based approach. 1540 mRNA diagnostic biomarker TP63 human uncertain prostate cancer H original research 16323473 Achievements in morphological diagnosis of prostatic cancer: alpha-methylacyl-coenzyme-A-racemase--a new marker of malignant cell transformation. 1541 mRNA diagnostic biomarker PIQ human tissue gastrointestinal cancer L original research 16322217 Cloning and characterization of a p53 and DNA damage down-regulated gene PIQ that codes for a novel calmodulin-binding IQ motif protein and is up-regulated in gastrointestinal cancers. 1542 mRNA diagnostic biomarker HMGI human tissue chorio cancer H original research 16306787 Expression of the high-mobility group protein HMGI(Y) in gestational trophoblastic diseases. 1543 mRNA diagnostic biomarker PIM1 human tissue prostate cancer H original research 16299799 Overexpression of PIM-1 is a potential biomarker in prostate carcinoma. 1544 mRNA diagnostic biomarker KIT human uncertain renal cancer H original research 16299227 Clear cell sarcoma of the kidney: up-regulation of neural markers with activation of the sonic hedgehog and Akt pathways. 1545 mRNA diagnostic biomarker EPCAM human tissue renal cancer clear cell renal cell cancer L original research 16298915 The tissue micro-array as a translational research tool for biomarker profiling and validation. 1546 mRNA diagnostic biomarker DICER1 human uncertain brain tumor uncertain review 16245217 The diagnosis and therapy of brain tumours 1547 mRNA diagnostic biomarker RKIP human tissue breast cancer H original research 16243812 Reduction of Raf-1 kinase inhibitor protein expression correlates with breast cancer metastasis. 1548 mRNA diagnostic biomarker GCLC human uncertain leukaemia H original research 16239001 Role of gamma-glutamyl cysteine synthetase (gamma-GCS) gene expression as marker of drug sensitivity in acute myeloid leukemias. 1549 mRNA diagnostic biomarker CDKN2A human "tissue,serum" esophageal cancer esophageal squamous cell cancer H original research 16227635 "Aberrant p16 methylation, a possible epigenetic risk factor in familial esophageal squamous cell carcinoma." 1550 mRNA diagnostic biomarker CRABP2 human tissue prostate cancer L original research 16211222 Cellular retinoic acid-binding protein 2 is down-regulated in prostate cancer. 1551 mRNA diagnostic biomarker TERT human tissue breast cancer H original research 16211220 "Expression of human telomerase reverse transcriptase gene and protein, and of estrogen and progesterone receptors, in breast tumors: preliminary data from neo-adjuvant chemotherapy." 1552 mRNA diagnostic biomarker FOXP3 human tissue leukaemia H original research 16193085 "FOXP3, a selective marker for a subset of adult T-cell leukaemia/lymphoma." 1553 mRNA diagnostic biomarker TYMS human uncertain colorectal cancer H original research 16182121 Relationships between promoter polymorphisms in the thymidylate synthase gene and mRNA levels in colorectal cancers. 1554 mRNA diagnostic biomarker "APE1,XRCC1" human uncertain bladder cancer H original research 16144922 APE1 and XRCC1 protein expression levels predict cancer-specific survival following radical radiotherapy in bladder cancer. 1555 mRNA diagnostic biomarker "ECM1,TMPRSS4" human uncertain thyroid cancer H original research 16135921 ECM1 and TMPRSS4 are diagnostic markers of malignant thyroid neoplasms and improve the accuracy of fine needle aspiration biopsy. 1556 mRNA diagnostic biomarker "TSLC1,IGSF4" human tissue uncertain L original research 16128739 "Involvement of a cell adhesion molecule, TSLC1/IGSF4, in human oncogenesis." 1557 mRNA diagnostic biomarker PKP3 human uncertain lung cancer non-small cell lung carcinoma H original research 16103059 Plakophilin 3 oncogene as prognostic marker and therapeutic target for lung cancer. 1558 mRNA diagnostic biomarker CD99 human uncertain Ewing sarcoma H original research 16096383 Ewing sarcoma family of tumors. 1559 mRNA diagnostic biomarker TP63 human tissue salivary cancer salivary gland cancer H original research 16084953 Differential expression of p63 isotypes (DeltaN and TA) in salivary gland neoplasms: biological and diagnostic implications. 1560 mRNA diagnostic biomarker CAV3 human tissue rhabdomyosarcoma uncertain original research 16082247 Caveolin-3 is a sensitive and specific marker for rhabdomyosarcoma. 1561 mRNA diagnostic biomarker "IFI27,CDKN1B" human uncertain head and neck cancer L(p27Kip1) original research 16077910 Basic investigation on the development of molecular targeting therapy against cyclin-dependent kinase inhibitor p27Kip1 in head and neck cancer cells. 1562 mRNA diagnostic biomarker "UC1,MUC5AC" human tissue pancreatic cancer H original research 16052519 Quantitative analysis of MUC1 and MUC5AC mRNA in pancreatic juice for preoperative diagnosis of pancreatic cancer. 1563 mRNA diagnostic biomarker "HIF1A,VEGF" human tissue rectal cancer H(HIF1A) original research 16052307 "Hypoxia, angiogenesis and apoptosis markers in locally advanced rectal cancer." 1564 mRNA diagnostic biomarker PCA1 human tissue prostate cancer H original research 16033822 High expression of a new marker PCA-1 in human prostate carcinoma. 1565 mRNA diagnostic biomarker "MEMD,ALCAM" human tissue esophageal cancer esophageal squamous cell cancer H original research 16024937 MEMD/ALCAM: a potential marker for tumor invasion and nodal metastasis in esophageal squamous cell carcinoma. 1566 mRNA diagnostic biomarker "HSP27,HSP86" rat uncertain breast cancer H(HSP27) original research 16003757 "Gene expression profiling in the mammary gland of rats treated with 7,12-dimethylbenzaanthracene." 1567 mRNA diagnostic biomarker SEREX human serum lymphoma uncertain original research 15998965 Identification of lymphoma-associated antigens using SEREX. 1568 mRNA diagnostic biomarker "GAL,POU5F1" human tissue embryonal cancer H(GAL) original research 15994931 Differentiation of human embryonal carcinomas in vitro and in vivo reveals expression profiles relevant to normal development. 1569 mRNA diagnostic biomarker GPBAR1 human tissue prostate cancer H original research 15979782 Transcript quantification of Dresden G protein-coupled receptor (D-GPCR) in primary prostate cancer tissue pairs. 1570 mRNA diagnostic biomarker UNG human tissue esophageal cancer esophageal squamous cell cancer H original research 15969084 Cloning of human uracil N-glycosylase and its detection in cancer tissues by quantitative RT-PCR. 1571 mRNA diagnostic biomarker "PLAP,KIT,POU5F1" human uncertain stromal tumor gonadal stromal cancer H(KIT) original research 15948118 Identification of germ cells at risk for neoplastic transformation in gonadoblastoma: an immunohistochemical study for OCT3/4 and TSPY. 1572 mRNA diagnostic biomarker BRAF human uncertain thyroid cancer uncertain review 15947100 BRAF mutation in thyroid cancer. 1573 mRNA diagnostic biomarker STMN1 human serum breast cancer H original research 15946792 A soluble lymphocyte activation gene-3 (sLAG-3) protein as a prognostic factor in human breast cancer expressing estrogen or progesterone receptors. 1574 mRNA diagnostic biomarker SLC16A10 human tissue bladder cancer H original research 15946493 [Correlation of clusterin expression to prognosis of bladder carcinoma]. 1575 mRNA diagnostic biomarker HIG2 human plasma renal cancer L original research 15930302 "Hypoxia-inducible protein 2 (HIG2), a novel diagnostic marker for renal cell carcinoma and potential target for molecular therapy." 1576 mRNA diagnostic biomarker NMB human tissue chondrosarcoma extraskeletal myxoid chondrosarcoma H original research 15920699 The gene expression profile of extraskeletal myxoid chondrosarcoma. 1577 mRNA diagnostic biomarker WT1 human uncertain Wilms' tumor H review 15920488 Wilms' tumour gene 1 (WT1) in human neoplasia. 1578 mRNA diagnostic biomarker "NPEPPS,HK3" human tissue prostate cancer uncertain review 15911097 Human tissue kallikrein gene family: applications in cancer. 1579 mRNA diagnostic biomarker "PCDHB15,WBSCR17,IGF1,GYPC,CYGB,ACTG2,PRRT1,ZBTB32,OR51B4,CCL8,TMEFF2,SALL3,GPSM1,MAGEA8,SALL1" human uncertain prostate cancer uncertain original research 15899813 Functional epigenomics identifies genes frequently silenced in prostate cancer. 1580 mRNA diagnostic biomarker INI1 human uncertain "teratoid/rhabdoid tumor,choroid plexus carcinoma" atypical teratoid/rhabdoid tumor L original research 15892296 INI1 protein expression distinguishes atypical teratoid/rhabdoid tumor from choroid plexus carcinoma. 1581 mRNA diagnostic biomarker ILK human tissue prostate cancer H original research 15870868 ILK as a potential marker gene to ascertain specific adenocarcinoma cell mRNA isolation from frozen prostate biopsy tissue sections. 1582 mRNA diagnostic biomarker CDKN2A human tissue squamous cell cancer H original research 15870532 Human papillomavirus infection and p16(INK4a) protein expression in vulvar intraepithelial neoplasia and invasive squamous cell carcinoma. 1583 mRNA diagnostic biomarker EBAG9 mice tissue renal cancer H original research 15867365 Estrogen receptor-binding fragment-associated antigen 9 is a tumor-promoting and prognostic factor for renal cell carcinoma. 1584 mRNA diagnostic biomarker HPSE human uncertain gastric cancer H original research 15844185 Detection of peritoneal micrometastasis by reverse transcriptase-polymerase chain reaction for heparanase mRNA and cytology in peritoneal wash samples. 1585 mRNA diagnostic biomarker CDKN2A human tissue oral cancer oral squamous cell carcinoma H original research 15842853 The p16 methylation in oral leukoplakia and oral squamous cell carcinoma. 1586 mRNA diagnostic biomarker PPJ human tissue pancreatic cancer H original research 15841046 "Expression of mesothelin mRNA in pure pancreatic juice from patients with pancreatic carcinoma, intraductal papillary mucinous neoplasm of the pancreas, and chronic pancreatitis." 1587 mRNA diagnostic biomarker ODC1 human tissue colorectal cancer H original research 15818733 Ornithine decarboxylase gene is overexpressed in colorectal carcinoma. 1588 mRNA diagnostic biomarker HIF1A human uncertain upper urinary tract transitional cell cancer H original research 15814637 Expression of hypoxia-inducible factor-1alpha protein predicts survival in patients with transitional cell carcinoma of the upper urinary tract. 1589 mRNA diagnostic biomarker GSTP1 human uncertain prostate cancer L original research 15800905 "Ethnic group-related differences in CpG hypermethylation of the GSTP1 gene promoter among African-American, Caucasian and Asian patients with prostate cancer." 1590 mRNA diagnostic biomarker NPEPPS human "tissue,plasma" prostate cancer L original research 15799824 Prostate-specific antigen modulates the expression of genes involved in prostate tumor growth. 1591 mRNA diagnostic biomarker "VEGF,AP1S2" human "tissue,blood" cervical cancer H original research 15790444 "The expression of cyclooxygenase-2, VEGF and PGs in CIN and cervical carcinoma." 1592 mRNA diagnostic biomarker CHI3L1 human uncertain glioma H original research 15788675 YKL-40 is a differential diagnostic marker for histologic subtypes of high-grade gliomas. 1593 mRNA diagnostic biomarker REG4 human tissue prostate cancer H original research 15788672 Reg IV: a promising marker of hormone refractory metastatic prostate cancer. 1594 mRNA diagnostic biomarker RAI3 human tissue breast cancer H original research 15788639 Identification of RAI3 as a therapeutic target for breast cancer. 1595 mRNA diagnostic biomarker "BRCA1,NDRG1" human tissue gastric cancer L(TP53) original research 15761963 A microarray-based gastric carcinoma prewarning system. 1596 mRNA diagnostic biomarker FXYD5 human tissue melanoma H original research 15751018 Clinicopathologic significance of dysadherin expression in cutaneous malignant melanoma: immunohistochemical analysis of 115 patients. 1597 mRNA diagnostic biomarker "CDC2,CDK1" human tissue esophageal cancer esophageal adenocarcinoma H original research 15725809 CDC2/CDK1 expression in esophageal adenocarcinoma and precursor lesions serves as a diagnostic and cancer progression marker and potential novel drug target. 1598 mRNA diagnostic biomarker "SP1,SP3" human serum prostate cancer H original research 15708372 Sp1 and Sp3 transcription factors upregulate the proximal promoter of the human prostate-specific antigen gene in prostate cancer cells. 1599 mRNA diagnostic biomarker "CDC20,MT2A" human tissue gastric cancer H original research 15701830 Identification of gastric cancer-related genes using a cDNA microarray containing novel expressed sequence tags expressed in gastric cancer cells. 1600 mRNA diagnostic biomarker ASCL1 human tissue gastrointestinal cancer gastrointestinal neuroendocrine carcinoma H original research 15701827 Aberrant expression of human achaete-scute homologue gene 1 in the gastrointestinal neuroendocrine carcinomas. 1601 mRNA diagnostic biomarker TFF3 human uncertain thyroid cancer L original research 15694668 Decreased relative expression level of trefoil factor 3 mRNA to galectin-3 mRNA distinguishes thyroid follicular carcinoma from adenoma. 1602 mRNA diagnostic biomarker TCFL5 human uncertain cervical cancer uncertain original research 15684709 Genomic and proteomic expression patterns in HPV-16 E6 gene transfected stable human carcinoma cell lines. 1603 mRNA diagnostic biomarker NMP22 human uncertain bladder cancer uncertain review 15684659 The clinical significance of molecular markers to bladder cancer. 1604 mRNA diagnostic biomarker "MLH1,MSH2,MSH6" human uncertain colorectal cancer L original research 15680406 Presymptomatic diagnosis using a deletion of a single codon in families with hereditary non-polyposis colorectal cancer. 1605 mRNA diagnostic biomarker TFEB human tissue renal cancer uncertain original research 15644781 "Renal carcinomas with the t(6;11)(p21;q12): clinicopathologic features and demonstration of the specific alpha-TFEB gene fusion by immunohistochemistry, RT-PCR, and DNA PCR." 1606 mRNA diagnostic biomarker "ASPL,TFE3" human tissue soft part sarcoma alveolar soft part sarcoma uncertain original research 15634444 Detection of ASPL-TFE3 fusion gene by reverse transcriptase polymerase chain reaction in paraffin-embedded tumor tissues of alveolar soft part sarcoma. 1607 mRNA diagnostic biomarker L1TD1P1 human uncertain cutaneous cancer H original research 15634221 Ultraviolet-induced transformation of keratinocytes: possible involvement of long interspersed element-1 reverse transcriptase. 1608 mRNA diagnostic biomarker GPC3 mice tissue hepatocellular cancer H original research 15623647 "Mouse homologue of a novel human oncofetal antigen, glypican-3, evokes T-cell-mediated tumor rejection without autoimmune reactions in mice." 1609 mRNA diagnostic biomarker MCM3 human tissue uncertain H original research 15623617 Cancer-associated expression of minichromosome maintenance 3 gene in several human cancers and its involvement in tumorigenesis. 1610 mRNA diagnostic biomarker ADAM8 human "tissue,serum" lung cancer non-small-cell lung cancer H original research 15623614 ADAM8 as a novel serological and histochemical marker for lung cancer. 1611 mRNA diagnostic biomarker FHIT human uncertain gastric cancer L original research 15609389 Loss of FHIT expression in gastric mucosa of patients with family histories of gastric cancer and Helicobacter pylori infection. 1612 mRNA diagnostic biomarker "PSMA,HPN,DD3,PCA3" human tissue prostate cancer H(PCA3) original research 15609297 Use of multiple biomarkers for a molecular diagnosis of prostate cancer. 1613 mRNA diagnostic biomarker "ANXA4,PPIF,CTSD,LGALS1,ENO1,PRDX1,TM2D1,S100A8" human tissue pancreatic cancer H original research 15604267 Protein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry. 1614 mRNA diagnostic biomarker SELDI human tissue prostate cancer L(inhibitor-1) original research 15592032 Analysis of prostate cancer by proteomics using tissue specimens. 1615 mRNA diagnostic biomarker FATE human tissue hepatocellular cancer H original research 15580283 Immunohistochemical analysis of the expression of FATE/BJ-HCC-2 antigen in normal and malignant tissues. 1616 mRNA diagnostic biomarker TP53 human uncertain esophageal cancer H original research 15555357 Significance of p53 gene mutation and P53 protein expression abnormality on the prognosis of esophageal cancer: a meta-analysis study. 1617 mRNA diagnostic biomarker "MEMD,CD24" human uncertain prostate cancer H original research 15532095 Expression profiling of microdissected matched prostate cancer samples reveals CD166/MEMD and CD24 as new prognostic markers for patient survival 1618 mRNA diagnostic biomarker APC human tissue breast cancer H(CEA) original research 15508191 "Detection of tumor markers including carcinoembryonic antigen, APC, and cyclin D2 in fine-needle aspiration fluid of breast." 1619 mRNA diagnostic biomarker APC human tissue breast cancer H(CEA) original research 15506825 "Detection of Tumor Markers Including Carcinoembryonic Antigen, APC, and Cyclin D2 in Fine-Needle Aspiration Fluid of Breast." 1620 mRNA diagnostic biomarker HMSH2 human tissue hepatocellular cancer L original research 15498213 Methylation of mismatch repair gene (MMR) in primary hepatocellular carcinoma. 1621 mRNA diagnostic biomarker ERBB human tissue breast cancer H original research 15494857 Real-time PCR quantification of c-erbB-2 gene is an alternative for FISH in the clinical management of breast carcinoma patients. 1622 mRNA diagnostic biomarker RNF43 human tissue colorectal cancer H original research 15492824 A novel oncoprotein RNF43 functions in an autocrine manner in colorectal cancer. 1623 mRNA diagnostic biomarker HRPT2 human uncertain thyroid cancer uncertain original research 15492263 Gene expression of parathyroid tumors: molecular subclassification and identification of the potential malignant phenotype. 1624 mRNA diagnostic biomarker TP63 human uncertain breast cancer H original research 15489655 p63 expression in breast cancer: a highly sensitive and specific marker of metaplastic carcinoma. 1625 mRNA diagnostic biomarker PLAUR human "tissue,blood" nephroblastoma H original research 15486896 Role of urokinase plasminogen activator and its receptor in metastasis and invasion of neuroblastoma. 1626 mRNA diagnostic biomarker CLUAP1 human uncertain colon cancer H original research 15480429 Isolation and characterization of a novel gene CLUAP1 whose expression is frequently upregulated in colon cancer. 1627 mRNA diagnostic biomarker TP53 human "tissue,serum" colorectal cancer H original research 15472522 Serum p53 antibodies in patients affected with ulcerative colitis. 1628 mRNA diagnostic biomarker MUC4 human uncertain pancreatic cancer H original research 15461591 The antagonistic regulation of human MUC4 and ErbB-2 genes by the Ets protein PEA3 in pancreatic cancer cells: implications for the proliferation/differentiation balance in the cells. 1629 mRNA diagnostic biomarker "CDX2,P504S" human uncertain colorectal cancer L(CDX2) original research 15389251 Use of novel immunohistochemical markers expressed in colonic adenocarcinoma to distinguish primary ovarian tumors from metastatic colorectal carcinoma. 1630 mRNA diagnostic biomarker CA15P3 human blood breast cancer H original research 15375015 Mammaglobin as a novel breast cancer biomarker: multigene reverse transcription-PCR assay and sandwich ELISA. 1631 mRNA diagnostic biomarker LRRC15 human tissue breast cancer H original research 15368894 High lib mRNA expression in breast carcinomas. 1632 mRNA diagnostic biomarker TERT human blood leukemia H original research 15367406 hTERT expression and prognosis in B-chronic lymphocytic leukemia. 1633 mRNA diagnostic biomarker TADG human tissue ovarian cancer H original research 15361711 The transmembrane protease serine (TMPRSS3/TADG-12) D variant: a potential candidate for diagnosis and therapeutic intervention in ovarian cancer. 1634 mRNA diagnostic biomarker BIRC5 human uncertain gastric cancer H(survivin) original research 15361297 Expression of survivin mRNA in peritoneal lavage fluid from patients with gastric carcinoma. 1635 mRNA diagnostic biomarker PTGS2 human tissue colorectal cancer H(COX-2) original research 15361286 Relationship between COX-2 expression and clinicopathological features of colorectal cancers. 1636 mRNA diagnostic biomarker TERT human uncertain thyroid cancer H original research 15355904 Human telomerase reverse transcriptase gene expression and the surgical management of suspicious thyroid tumors. 1637 mRNA diagnostic biomarker CDKN2A human tissue cervical cancer H original research 15339339 Protein p16 as a marker of dysplastic and neoplastic alterations in cervical epithelial cells. 1638 mRNA diagnostic biomarker CDX2 human tissue neuroblastoma L original research 15316316 CDX-2 homeobox gene product expression in neuroendocrine tumors: its role as a marker of intestinal neuroendocrine tumors. 1639 mRNA diagnostic biomarker VEGFA human uncertain lymphoma H original research 15311211 Vascular endothelial growth factor-A is expressed both on lymphoma cells and endothelial cells in angioimmunoblastic T-cell lymphoma and related to lymphoma progression. 1640 mRNA diagnostic biomarker "ANXA8L1,FHA" human serum breast cancer uncertain original research 15289310 Autoantibodies to Annexin XI-A and Other Autoantigens in the Diagnosis of Breast Cancer. 1641 mRNA diagnostic biomarker "CLDN4,S100A1" human tissue ovarian cancer H original research 15277215 Differential gene expression in ovarian carcinoma: identification of potential biomarkers. 1642 mRNA diagnostic biomarker ASCL1 human uncertain neuroblastoma H original research 15272537 Human achaete-scute homologue (hASH1) mRNA level as a diagnostic marker to distinguish esthesioneuroblastoma from poorly differentiated tumors arising in the sinonasal tract. 1643 mRNA diagnostic biomarker BCL2 human uncertain colon cancer L original research 15237588 Bcl2 expression and its correlation with neuroendocrine differentiation in colon carcinomas. 1644 mRNA diagnostic biomarker ERBB2 human uncertain "breast cancer,ovarian cancer" H original research 15235125 Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells. 1645 mRNA diagnostic biomarker DNALI1 human tissue hepatocellular cancer uncertain original research 15221469 "A novel diagnostic marker, p28GANK distinguishes hepatocellular carcinoma from potential mimics." 1646 mRNA diagnostic biomarker HIFs human uncertain renal cancer H original research 15217953 Effect of radiation and ibuprofen on normoxic renal carcinoma cells overexpressing hypoxia-inducible factors by loss of von Hippel-Lindau tumor suppressor gene function. 1647 mRNA diagnostic biomarker "HMLH1,HMSH2" human tissue colorectal cancer L original research 15216397 Microsatellite instability and hMLH1 and hMSH2 gene expression in Taiwanese hereditary nonpolyposis colorectal cancer. 1648 mRNA diagnostic biomarker ANO1 human "tissue,serum" gastrointestinal cancer gastrointestinal stromal cancer H(DOG1) original research 15215166 "The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status." 1649 mRNA diagnostic biomarker KLK6 human tissue ovarian cancer H original research 15207701 Cloning and characterization of novel isoforms of the human kallikrein 6 gene. 1650 mRNA diagnostic biomarker WT1 human blood leukaemia H original research 15206129 Development of a new inspection diagnostic method: genetic screening of cancer. 1651 mRNA diagnostic biomarker EFHC1 human tissue esophageal cancer H original research 15199388 Clinical significance of elongation factor-1 delta mRNA expression in oesophageal carcinoma. 1652 mRNA diagnostic biomarker ERBB2 human blood breast cancer H original research 15194824 HER-2 gene amplification can be acquired as breast cancer progresses. 1653 mRNA diagnostic biomarker BIRC5 human tissue lymphoma diffuse large B-cell lymphoma H original research 15191665 Analysis of survivin expression in subtypes of lymphoma. 1654 mRNA diagnostic biomarker ALK human tissue lymphoma H original research 15188137 Expression of anaplastic lymphoma kinase in soft tissue tumors: an immunohistochemical and molecular study of 249 cases. 1655 mRNA diagnostic biomarker ANXA1 human uncertain leukaemia H original research 15183626 Simple diagnostic assay for hairy cell leukaemia by immunocytochemical detection of annexin A1 (ANXA1). 1656 mRNA diagnostic biomarker AKR1B1 human uncertain adrenocortical cancer sporadic adrenocortical tumor L original research 15181092 Decreased expression of cyclic adenosine monophosphate-regulated aldose reductase (AKR1B1) is associated with malignancy in human sporadic adrenocortical tumors. 1657 mRNA diagnostic biomarker POTEM human tissue prostate cancer uncertain original research 15176051 "P704P, P712P, and P775P: A genomic cluster of prostate-specific genes." 1658 mRNA diagnostic biomarker "CEACAM5,PPA1,RPL3" human uncertain gastric cancer H(RPL3) original research 15154633 Combination of L-3-phosphoserine phosphatase and CEA using real-time RT-PCR improves accuracy in detection of peritoneal micrometastasis of gastric cancer. 1659 mRNA diagnostic biomarker ERBB3 human tissue melanoma H original research 15150091 Expression profiling of t(12;22) positive clear cell sarcoma of soft tissue cell lines reveals characteristic up-regulation of potential new marker genes including ERBB3. 1660 mRNA diagnostic biomarker "EWSFLI1,EWS,ERG,PAX3,FKHR,PAX7,FKHR" human uncertain Ewing sarcoma H original research 15146558 Profiling and functional annotation of mRNA gene expression in pediatric rhabdomyosarcoma and Ewing's sarcoma. 1661 mRNA diagnostic biomarker KLK8 human tissue ovarian cancer epithelial ovarian cancer L original research 15138549 Human kallikrein 8 (hK8/TADG-14) expression is associated with an early clinical stage and favorable prognosis in ovarian cancer. 1662 mRNA diagnostic biomarker FKBP51 human tissue prostate cancer H original research 15131019 Identification and validation of novel androgen-regulated genes in prostate cancer. 1663 mRNA diagnostic biomarker WT1 human uncertain adenoid cystic cancer H original research 15084840 Adenomatoid tumors of the female and male genital tracts express WT1. 1664 mRNA diagnostic biomarker PCADM-1 human tissue prostate cancer uncertain original research 15073124 Evidence for prostate cancer-associated diagnostic marker-1: immunohistochemistry and in situ hybridization studies. 1665 mRNA diagnostic biomarker CITED1 human tissue thyroid cancer papillary thyroid carcinoma H original research 15072698 CITED1 protein expression suggests Papillary Thyroid Carcinoma in high throughput tissue microarray-based study. 1666 mRNA diagnostic biomarker KLK3 human tissue prostate cancer H original research 15059887 Kallikrein 4 is a predominantly nuclear protein and is overexpressed in prostate cancer. 1667 mRNA diagnostic biomarker TP53 human uncertain breast cancer H original research 15028887 Mutation and overexpression of p53 as a prognostic factor in canine mammary tumors. 1668 mRNA diagnostic biomarker EZR human uncertain prostate cancer H original research 15028477 Expression of ezrin in prostatic intraepithelial neoplasia. 1669 mRNA diagnostic biomarker HMGN2P46 human tissue prostate cancer H original research 15027122 D-PCa-2: a novel transcript highly overexpressed in human prostate and prostate cancer. 1670 mRNA diagnostic biomarker BAAT human uncertain gastric cancer uncertain original research 15017590 Standardized approach for microsatellite instability detection in gastric carcinomas. 1671 mRNA diagnostic biomarker SPP1 human serum pancreatic cancer H(OPN) original research 15006928 Evaluation of osteopontin as biomarker for pancreatic adenocarcinoma. 1672 mRNA diagnostic biomarker KLK2 human tissue ovarian cancer H original research 15004490 Immunofluorometric quantification of human kallikrein 5 expression in ovarian cancer cytosols and its association with unfavorable patient prognosis. 1673 mRNA diagnostic biomarker "CEACAM5,UCHL1" human tissue thyroid cancer medullary thyroid carcinoma H original research 14962731 PGP9.5 mRNA could contribute to the molecular-based diagnosis of medullary thyroid carcinoma. 1674 mRNA diagnostic biomarker HARLP rat uncertain hepatocellular cancer uncertain original research 14768008 Detection and identification of tumor-associated protein variants in human hepatocellular carcinomas. 1675 mRNA diagnostic biomarker TP53 human serum uncertain H review 14743744 Histopathology and tumor markers. 1676 mRNA diagnostic biomarker GPBP1L1 human tissue breast cancer uncertain original research 14734448 DetectionofbreastcancerinnippleaspiratefluidbyCpGislandhypermethylation. 1677 mRNA diagnostic biomarker "OLIG1,OLIG2" human tissue glioma H original research 14730454 Expression of oligodendrocyte lineage genes in oligodendroglial and astrocytic gliomas. 1678 mRNA diagnostic biomarker CMD1B human plasma inflammatory pseudotumor uncertain original research 14720144 Inflammatory pseudotumor-like follicular dendritic cell tumor of the spleen. 1679 mRNA diagnostic biomarker HMGA1 human tissue hepatocellular cancer H original research 14714251 "High mobility group A1 is expressed in metastatic adenocarcinoma to the liver and intrahepatic cholangiocarcinoma, but not in hepatocellular carcinoma: its potential use in the diagnosis of liver neoplasms." 1680 mRNA diagnostic biomarker "MUC1,CDH6" human "tissue,blood" renal cancer uncertain original research 14695146 Rapid and sensitive detection of messenger RNA expression for molecular differential diagnosis of renal cell carcinoma. 1681 mRNA diagnostic biomarker PTPN6 human plasma leukaemia L(SHP1) original research 14691303 Activated proliferation of B-cell lymphomas/leukemias with the SHP1 gene silencing by aberrant CpG methylation. 1682 mRNA diagnostic biomarker "EBER,CD3D" human uncertain lymphoma uncertain original research 14690577 "Study of the pathology, immunophenotype, etiology and genetic marker of NK/T-cell lymphoma." 1683 mRNA diagnostic biomarker CA9 human tissue renal cancer H original research 14660102 Quantification of G250 mRNA expression in renal epithelial neoplasms by real-time reverse transcription-PCR of dissected tissue from paraffin sections. 1684 mRNA diagnostic biomarker MUC4 human tissue "mesothelioma,lung cancer" "epithelial mesothelioma,lung adenocarcinoma" uncertain original research 14657954 Diagnostic value of MUC4 immunostaining in distinguishing epithelial mesothelioma and lung adenocarcinoma. 1685 mRNA diagnostic biomarker SCCA human tissue oral cancer H original research 14654899 Basic and clinical studies on quantitative analysis of lymph node micrometastasis in oral cancer. 1686 mRNA diagnostic biomarker HMGA2 human tissue pancreatic cancer H original research 14647145 An increased high-mobility group A2 expression level is associated with malignant phenotype in pancreatic exocrine tissue. 1687 mRNA diagnostic biomarker STAG1 human uncertain "breast cancer,ovarian cancer" H original research 14639658 EGF- and cell-cycle-regulated STAG1/PMEPA1/ERG1.2 belongs to a conserved gene family and is overexpressed and amplified in breast and ovarian cancer. 1688 mRNA diagnostic biomarker TALLA human uncertain leukemia uncertain original research 14633590 "A tetraspanin-family protein, T-cell acute lymphoblastic leukemia-associated antigen 1, is induced by the Ewing's sarcoma-Wilms' tumor 1 fusion protein of desmoplastic small round-cell tumor." 1689 mRNA diagnostic biomarker "SAGE,HAGE" human tissue lung cancer H original research 14624785 SAGE mRNA expression in advanced-stage lung cancers. 1690 mRNA diagnostic biomarker GSTP1 human uncertain uncertain L original research 14619983 Does glutathione S-transferase Pi (GST-Pi) a marker protein for cancer? 1691 mRNA diagnostic biomarker LGALS5 human tissue thyroid cancer H original research 14614051 Expression of galectin-3 in normal and malignant thyroid tissue by quantitative PCR and immunohistochemistry. 1692 mRNA diagnostic biomarker COX17 human tissue lung cancer non-small cell lung cancer H original research 14612491 Identification of COX17 as a therapeutic target for non-small cell lung cancer. 1693 mRNA diagnostic biomarker KIT human tissue gastrointestinal cancer gastrointestinal stromal cancer H original research 14606094 Expression and mutation of c-kit gene in gastrointestinal stromal tumors. 1694 mRNA diagnostic biomarker RAD51 human uncertain uncertain L review 14599770 Homologous recombination and cell cycle checkpoints: Rad51 in tumour progression and therapy resistance. 1695 mRNA diagnostic biomarker "APE1,APEX1" human tissue uncertain H original research 14599768 APE/Ref-1 and the mammalian response to genotoxic stress. 1696 mRNA diagnostic biomarker TADG human tissue cervical cancer H original research 14584072 The novel serine protease tumor-associated differentially expressed gene-15 (matriptase/MT-SP1) is highly overexpressed in cervical carcinoma. 1697 mRNA diagnostic biomarker FSGS human tissue renal cancer uncertain original research 14569107 Gene expression profiles of podocyte-associated molecules as diagnostic markers in acquired proteinuric diseases. 1698 mRNA diagnostic biomarker HOSTS human tissue ovarian cancer H original research 14562052 Characterization of novel human ovarian cancer-specific transcripts (HOSTs) identified by serial analysis of gene expression. 1699 mRNA diagnostic biomarker UCHL1 human tissue mesenchymal cancer H original research 14559978 Protein gene product 9.5 (PGP 9.5) is not a specific marker of neural and nerve sheath tumors: an immunohistochemical study of 95 mesenchymal neoplasms. 1700 mRNA diagnostic biomarker REG4 human tissue colorectal cancer colorectal adenoma H original research 14550954 Overexpression of Reg IV in colorectal adenoma. 1701 mRNA diagnostic biomarker "PTEN,MMAC1,TEP1,RET,PTC,PAX8,PPAR,TSHR" human tissue thyroid cancer "H(RET,TSHR),L(PTEN)" original research 12975039 Thyroid carcinomas of the follicular epithelium: tumor markers and oncogenes. 1702 mRNA diagnostic biomarker SIRT2 human tissue glioma L original research 12963026 Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene. 1703 mRNA diagnostic biomarker PTEN human tissue uterine cancer endometrial carcinoma L original research 12948417 PTEN coding product: a marker for tumorigenesis and progression of endometrial carcinoma. 1704 mRNA diagnostic biomarker TSLC1 human tissue lung cancer non-small cell lung cancer L original research 12942568 Clinical implication and prognostic significance of the tumor suppressor TSLC1 gene detected in adenocarcinoma of the lung. 1705 mRNA diagnostic biomarker OIT3 human tissue hepatocellular cancer L original research 12939600 A novel liver-specific zona pellucida domain containing protein that is expressed rarely in hepatocellular carcinoma. 1706 mRNA diagnostic biomarker VHL human tissue renal cancer H original research 12923786 Proteomic changes in renal cancer and co-ordinate demonstration of both the glycolytic and mitochondrial aspects of the Warburg effect. 1707 mRNA diagnostic biomarker RAB5 human tissue lung cancer non-small cell lung cancer H original research 12901617 Over-expression of the RAB5 gene in human lung adenocarcinoma cells with high metastatic potential. 1708 mRNA diagnostic biomarker FHIT human uncertain cervical cancer L original research 12893195 Reduced Fhit expression in cervical carcinoma: correlation with tumor progression and poor prognosis. 1709 mRNA diagnostic biomarker "KLK6,KLK10,KLK11" human tissue ovarian cancer H original research 12876620 Tissue kallikreins: new players in normal and abnormal cell growth? 1710 mRNA diagnostic biomarker KLK14 human tissue prostate cancer H original research 12858357 Differential expression of the human kallikrein gene 14 (KLK14) in normal and cancerous prostatic tissues. 1711 mRNA diagnostic biomarker "EREG,ERBB2" human tissue breast cancer H(ERBB2) original research 12855612 Gene expression profiles obtained from fine-needle aspirations of breast cancer reliably identify routine prognostic markers and reveal large-scale molecular differences between estrogen-negative and estrogen-positive tumors. 1712 mRNA diagnostic biomarker KLK11 human tissue ovarian cancer H original research 12845660 Favorable prognostic value of tissue human kallikrein 11 (hK11) in patients with ovarian carcinoma. 1713 mRNA diagnostic biomarker ERVE4 human tissue prostate cancer H original research 12833471 Detecting the expression of human endogenous retrovirus E envelope transcripts in human prostate adenocarcinoma. 1714 mRNA diagnostic biomarker "GAST,ICHA1,LYZ,MUC5,PSEN2" human uncertain gastric cancer uncertain original research 12833151 "Profiling, comparison and validation of gene expression in gastric carcinoma and normal stomach." 1715 mRNA diagnostic biomarker HGF human tissue cholangio cancer H original research 12819026 Identification of novel cellular targets in biliary tract cancers using global gene expression technology. 1716 mRNA diagnostic biomarker BMPS human uncertain leukaemia H original research 12801531 Expression of bone morphogenetic proteins in acute promyelocytic leukemia before and after combined all trans-retinoic acid and cytotoxic treatment. 1717 mRNA diagnostic biomarker WT1 human uncertain Wilms' tumor H original research 12796362 Two molecular subgroups of Wilms' tumors with or without WT1 mutations. 1718 mRNA diagnostic biomarker TYRP1 human tissue prostate cancer H original research 12792797 "Multiple tumor marker analyses (PSA, hK2, PSCA, trp-p8) in primary prostate cancers using quantitative RT-PCR." 1719 mRNA diagnostic biomarker NES1 human tissue breast cancer breast ductal cancer L original research 12788170 Loss of expression of the putative tumor suppressor NES1 gene in biopsy-proven ductal carcinoma in situ predicts for invasive carcinoma at definitive surgery. 1720 mRNA diagnostic biomarker GPC3 human serum hepatocellular cancer H original research 12788060 "Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker." 1721 mRNA diagnostic biomarker RECK human tissue breast cancer L original research 12767082 Matrix metalloproteinase inhibitor reversion-inducing cysteine-rich protein with Kazal motifs: a prognostic marker for good clinical outcome in human breast carcinoma. 1722 mRNA diagnostic biomarker TERT human tissue bladder cancer H original research 12765058 Detection of telomerase activity by semi-quantitative and in situ assays and quantification of hTERT expression in bladder carcinomas. 1723 mRNA diagnostic biomarker TSHR human tissue thyroid cancer epithelial thyroid cancers H original research 12727856 Methylation of the thyroid-stimulating hormone receptor gene in epithelial thyroid tumors: a marker of malignancy and a cause of gene silencing. 1724 mRNA diagnostic biomarker KLK human tissue ovarian cancer H original research 12727843 Parallel overexpression of seven kallikrein genes in ovarian cancer. 1725 mRNA diagnostic biomarker kallikreins human uncertain uncertain uncertain original research 12725528 Emerging interest in the kallikrein gene family for understanding and diagnosing cancer. 1726 mRNA diagnostic biomarker "MKI67,MKI67,PCNA" human uncertain urothelial cancer uncertain original research 12715166 Molecular pathology of non-invasive urothelial carcinomas (part I). 1727 mRNA diagnostic biomarker ANGPTL4 human tissue renal cancer H original research 12707035 Angiopoietin-like 4 is a proangiogenic factor produced during ischemia and in conventional renal cell carcinoma. 1728 mRNA diagnostic biomarker "TP53,MDM2" human plasma hematological tumor H(TP53) original research 12687276 Altered expression of p53 and MDM2 proteins in hematological malignancies. 1729 mRNA diagnostic biomarker S100 human uncertain melanoma H original research 12675527 A bioinformatic approach to the identification of candidate genes for the development of new cancer diagnostics. 1730 mRNA diagnostic biomarker MIC1 human tissue prostate cancer H original research 12671711 Quantitative analysis of macrophage inhibitory cytokine-1 (MIC-1) gene expression in human prostatic tissues. 1731 mRNA diagnostic biomarker TERT human tissue bladder cancer H original research 12656916 "Detection of telomerase status by semiquantitative and in situ assays, and by real-time reverse transcription-polymerase chain reaction (telomerase reverse transcriptase) assay in bladder carcinomas." 1732 mRNA diagnostic biomarker "MKI67,HTERT" human uncertain glioma H original research 12640105 KI-67 AND hTERT expression can aid in the distinction between malignant and benign pheochromocytoma and paraganglioma. 1733 mRNA diagnostic biomarker "HMLH1,HMSH2" human sputum lung cancer non-small cell lung cancer L original research 12639995 Inactivation of hMLH1 and hMSH2 by promoter methylation in primary non-small cell lung tumors and matched sputum samples. 1734 mRNA diagnostic biomarker "SDC2,SDC1" human tissue mesothelioma H original research 12635139 "Proteoglycans and WT1 as markers for distinguishing adenocarcinoma, epithelioid mesothelioma, and benign mesothelium." 1735 mRNA diagnostic biomarker "NPEPPS,PSM,EGFR,HER2,HER3,TOP2,KRT8,KRT18,VEGF,CD44,VIM,CAV1,CAV2" human tissue prostate cancer H(EGFR) original research 12624952 Gene expression profiles of protein kinases and phosphatases obtained by hybridization with cDNA arrays: molecular portrait of human prostate carcinoma. 1736 mRNA diagnostic biomarker KOC human uncertain uncertain H original research 12618877 KOC is a novel molecular indicator of malignancy. 1737 mRNA diagnostic biomarker TERT human tissue thyroid cancer H original research 12618337 Human telomerase reverse transcriptase (hTERT) gene expression in FNA samples from thyroid neoplasms. 1738 mRNA diagnostic biomarker "MKI67,IFI27" human tissue thyroid cancer H original research 12605367 "Parathyroid neoplasms: clinical, histopathological, and tissue microarray-based molecular analysis." 1739 mRNA diagnostic biomarker TERT human tissue glioma H original research 12592364 Clinical implications of quantitative real-time RT-PCR analysis of hTERT gene expression in human gliomas. 1740 mRNA diagnostic biomarker "GSTP1,AFP" rat tissue hepatocellular cancer L(GSTP1) original research 12561433 Quantitative analysis of p53 and related genes mRNA in rat hepatocarcinogenesis induced by 3'-Me-DAB. 1741 mRNA diagnostic biomarker UROC28 human tissue breast cancer H original research 12553037 Enhanced expression of the UROC28 gene in human breast cancer: relationship to ERBB2 gene expression. 1742 mRNA diagnostic biomarker BASE human tissue breast cancer H original research 12538848 Discovery of the breast cancer gene BASE using a molecular approach to enrich for genes encoding membrane and secreted proteins. 1743 mRNA diagnostic biomarker SIM2 human tissue prostate cancer L original research 12530058 Down's syndrome-associated single minded gene as a novel tumor marker. 1744 mRNA diagnostic biomarker TBPL1 human uncertain uncertain uncertain original research 12529983 Characterization of a fragment containing a putative TLP cDNA sequence. 1745 mRNA diagnostic biomarker TAF1 human uncertain colon cancer H original research 12519636 Quantification of human intestinal gene expression profiles using exfoliated colonocytes: a pilot study. 1746 mRNA diagnostic biomarker PTGS2 human tissue oral cancer H original research 12516959 Deregulated cyclooxygenase-2 expression in oral premalignant tissues. 1747 mRNA diagnostic biomarker ST13 human tissue hepatocellular cancer H(HSP70) original research 12500205 Expression profiling in multistage hepatocarcinogenesis: identification of HSP70 as a molecular marker of early hepatocellular carcinoma. 1748 mRNA diagnostic biomarker MUC5B human blood breast cancer H original research 12478674 Detection of bone marrow-disseminated breast cancer cells using an RT-PCR assay of MUC5B mRNA. 1749 mRNA diagnostic biomarker "EREG,PGR,PSEN2,BCl2,CTSD" human tissue breast cancer L(BCL2) original research 12462383 Age-dependent changes in breast cancer hormone receptors and oxidant stress markers. 1750 mRNA diagnostic biomarker "LGALS3,LGALS6,LGALS8" human plasma thyroid cancer medullary thyroid carcinoma H original research 12460332 Differential expression of galectin-3 in medullary thyroid carcinoma and C-cell hyperplasia. 1751 mRNA diagnostic biomarker JUND human uncertain lung cancer uncertain original research 12424143 Role and regulation of activator protein-1 in toxicant-induced responses of the lung. 1752 mRNA diagnostic biomarker "PTGS2,TP53" human tissue colorectal cancer H original research 12397273 "Molecular analysis of diminutive, flat, depressed colorectal lesions: are they precursors of polypoid adenoma or early stage carcinoma?" 1753 mRNA diagnostic biomarker GLI1 human uncertain cutaneous cancer H original research 12384550 Comparative gene expression profile analysis of GLI and c-MYC in an epithelial model of malignant transformation. 1754 mRNA diagnostic biomarker TP53 human tissue breast cancer H original research 12365217 p53 mutations as tumor markers in fine needle aspirates of palpable breast masses. 1755 mRNA diagnostic biomarker TERT human urine bladder cancer H original research 12352460 Detection of the presence of catalytic subunit mRNA associated with telomerase gene in exfoliated urothelial cells from patients with bladder cancer. 1756 mRNA diagnostic biomarker KRT20 human tissue colorectal cancer H original research 12237879 Quantification of CK20 gene and protein expression in colorectal cancer by RT-PCR and immunohistochemistry reveals inter- and intratumour heterogeneity. 1757 mRNA diagnostic biomarker "KLK6,KLK10,KLK11,NPEPPS,HK3" human "tissue,serum" prostate cancer "H(KLK6,KLK10,KLK11),L(NPEPPS)" review 12218299 Expanded human tissue kallikrein family--a novel panel of cancer biomarkers. 1758 mRNA diagnostic biomarker FCGR1A human tissue thyroid cancer H original research 12208673 "Differential expression of IgG Fc binding protein (FcgammaBP) in human normal thyroid tissue, thyroid adenomas and thyroid carcinomas." 1759 mRNA diagnostic biomarker RB1 human tissue eccrine porocarcinoma L original research 12207741 Aberrant expression of p16 and RB protein in eccrine porocarcinoma. 1760 mRNA diagnostic biomarker DNALI1 human tissue hepatocellular cancer H original research 12174370 Overexpression of p28/gankyrin in human hepatocellular carcinoma and its clinical significance. 1761 mRNA diagnostic biomarker "TERT,TERC" human tissue testicular cancer H(TERT) original research 12168080 Quantification of human telomerase reverse transcriptase mRNA in testicular germ cell tumors by quantitative fluorescence real-time RT-PCR. 1762 mRNA diagnostic biomarker procathepsin A human tissue lung cancer uncertain original research 12151090 Pronapsin A and B gene expression in normal and malignant human lung and mononuclear blood cells. 1763 mRNA diagnostic biomarker HMGI human uncertain mucinous cancer intraductal papillary mucinous tumor H original research 12142746 Diagnostic significance of high mobility group I(Y) protein expression in intraductal papillary mucinous tumors of the pancreas. 1764 mRNA diagnostic biomarker "KLK6,KLK10,KLK11" human tissue uncertain H original research 12142373 Human tissue kallikreins: a family of new cancer biomarkers. 1765 mRNA diagnostic biomarker TP53 human tissue head and neck cancer H original research 12127695 "The expression of p53, c-erbB-1 and c-erbB-2 molecules and their correlation with prognostic markers in patients with head and neck tumors." 1766 mRNA diagnostic biomarker MAGE human tissue ovarian cancer H original research 12115308 "mRNA detection of tumor-rejection genes BAGE, GAGE, and MAGE in peritoneal fluid from patients with ovarian carcinoma as a potential diagnostic tool." 1767 mRNA diagnostic biomarker FHIT human uncertain ovarian cancer epithelial ovarian cancer H original research 12112314 "Comparative analysis of loss of heterozygosity of specific chromosome 3, 13, 17, and X loci and TP53 mutations in human epithelial ovarian cancer." 1768 mRNA diagnostic biomarker PTEN human uncertain glioma L review 12084351 Pten signaling in gliomas. 1769 mRNA diagnostic biomarker "MET,DUSP9,PCNA,TOP2A,VIM" human tissue renal cancer H(MET) original research 12068634 Molecular portrait of human kidney carcinomas: the gene expression profiling of protein-tyrosine kinases and tyrosine phosphatases which controlled regulatory signals in the cells. 1770 mRNA diagnostic biomarker NDRG1 human tissue uncertain H original research 12046693 Enhanced expression of a novel protein in human cancer cells: a potential aid to cancer diagnosis. 1771 mRNA diagnostic biomarker MAGE human "tissue,serum" lung cancer H original research 12006991 Screening and identification of human lung cancer-related antigens. 1772 mRNA diagnostic biomarker TP53 human tissue laryngeal cancer H original research 11978553 P53 tumor suppressor gene mutations in laryngeal cancer and in recurrent disease following radiation therapy. 1773 mRNA diagnostic biomarker TP63 human tissue prostate cancer H original research 11956072 Alpha-methylacyl-CoA racemase: a new molecular marker for prostate cancer. 1774 mRNA diagnostic biomarker "WT1,WT2" human tissue mesothelioma H original research 11954027 The value of Wilms tumor susceptibility gene 1 in cytologic preparations as a marker for malignant mesothelioma. 1775 mRNA diagnostic biomarker ASCL1 human tissue lung cancer small cell lung cancer H original research 11948117 "Quantitative reverse transcription-polymerase chain reaction measurement of HASH1 (ASCL1), a marker for small cell lung carcinomas with neuroendocrine features." 1776 mRNA diagnostic biomarker AMACR human tissue prostate cancer H original research 11926890 alpha-Methylacyl coenzyme A racemase as a tissue biomarker for prostate cancer. 1777 mRNA diagnostic biomarker RPS12 human tissue cervical cancer squamous cell cervical carcinoma H original research 11920594 Identification and characterization of genes involved in the carcinogenesis of human squamous cell cervical carcinoma. 1778 mRNA diagnostic biomarker TP53 human tissue head and neck cancer head and neck squamous cell cancer H original research 11887018 Clinical applications of the diagnosis of p53 alterations in squamous cell carcinoma of the head and neck. 1779 mRNA diagnostic biomarker CA9 human tissue renal cancer H original research 11880110 Real-time quantitative reverse transcription-PCR assay for renal cell carcinoma-associated antigen G250. 1780 mRNA diagnostic biomarker RPS12 human tissue cervical cancer squamous cell cervical carcinoma H original research 11870519 Identification of molecular markers for the early detection of human squamous cell carcinoma of the uterine cervix. 1781 mRNA diagnostic biomarker TP53 human uncertain esophageal cancer esophageal squamous cell cancer H original research 11869317 p53 protein in esophageal mucosa of individuals at high risk of squamous cell carcinoma of the esophagus. 1782 mRNA diagnostic biomarker DEL human tissue neuroblastoma uncertain original research 11859407 Expression of DeltaNp73 is a molecular marker for adverse outcome in neuroblastoma patients. 1783 mRNA diagnostic biomarker HTSH human uncertain thyroid cancer H original research 11834126 High-level expression of human thyroid-stimulating hormone in Chinese hamster ovary cells by co-transfection of dicistronic expression vectors followed by a dual-marker amplification strategy. 1784 mRNA diagnostic biomarker "MMP1,TP53,CDH1" human tissue adenoid cystic cancer "H(TP53),L(CDH1)" original research 11812942 "Utility of MMP-1, p53, E-cadherin, and collagen IV immunohistochemical stains in the differential diagnosis of adenomas with misplaced epithelium versus adenomas with invasive adenocarcinoma." 1785 mRNA diagnostic biomarker UPP1 human tissue breast cancer H original research 11807789 Expression of uridine and thymidine phosphorylase genes in human breast carcinoma. 1786 mRNA diagnostic biomarker CD99 human uncertain fibromatose uncertain original research 11789717 CD99 immunoreactivity in atypical fibroxanthoma: a common feature of diagnostic value. 1787 mRNA diagnostic biomarker KLK11 human "tissue,plasma,serum" "ovarian cancer,prostate cancer" H original research 11782391 Human kallikrein 11: a new biomarker of prostate and ovarian carcinoma. 1788 mRNA diagnostic biomarker PAX5 human "tissue,plasma" "lymphoma,leukemia" B-lymphoblastic neoplasms uncertain review 11781220 Proteins encoded by genes involved in chromosomal alterations in lymphoma and leukemia: clinical value of their detection by immunocytochemistry. 1789 mRNA diagnostic biomarker RIE-1 human tissue "breast cancer,colon cancer" L original research 11773051 Loss of transgelin in breast and colon tumors and in RIE-1 cells by Ras deregulation of gene expression through Raf-independent pathways. 1790 mRNA diagnostic biomarker TERT human tissue urine bladder cancer H original research 11771177 Prospects for molecular research in urological oncology: bladder cancer. 1791 mRNA diagnostic biomarker SMAD4 human tissue adenocarcinoma L original research 11764071 Immunohistochemical labeling for the Dpc4 gene product is a specific marker for adenocarcinoma in biopsy specimens of the pancreas and bile duct. 1792 mRNA diagnostic biomarker NPEPPS human serum prostate cancer L original research 11757074 Involvement of the C-terminal end of the prostrate-specific antigen in a conformational epitope: characterization by proteolytic degradation of monoclonal antibody-bound antigen and mass spectrometry. 1793 mRNA diagnostic biomarker HK2 human tissue prostate cancer H original research 11753974 Comparison of human prostate specific glandular kallikrein 2 and prostate specific antigen gene expression in prostate with gene amplification and overexpression of prostate specific glandular kallikrein 2 in tumor tissue. 1794 mRNA diagnostic biomarker MUC4 human tissue pancreatic cancer H original research 11751498 Mucin (MUC) gene expression in human pancreatic adenocarcinoma and chronic pancreatitis: a potential role of MUC4 as a tumor marker of diagnostic significance. 1795 mRNA diagnostic biomarker MSLN human tissue pancreatic cancer H original research 11751476 Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE). 1796 mRNA diagnostic biomarker GPR183 human serum nasopharyngeal cancer uncertain original research 11745260 Antibody response to Epstein-Barr virus Rta protein in patients with nasopharyngeal carcinoma: a new serologic parameter for diagnosis. 1797 mRNA diagnostic biomarker NES1 human tissue breast cancer H original research 11705853 "Analysis of normal epithelial cell specific-1 (NES1)/kallikrein 10 mRNA expression by in situ hybridization, a novel marker for breast cancer." 1798 mRNA diagnostic biomarker GLEA2 human "tissue,serum" glioma glioblastoma uncertain original research 11703362 Glioma-expressed antigen 2 (GLEA2): a novel protein that can elicit immune responses in glioblastoma patients and some controls. 1799 mRNA diagnostic biomarker UCHL1 human "tissue,serum" lung cancer H original research 11691811 Proteomics-based identification of protein gene product 9.5 as a tumor antigen that induces a humoral immune response in lung cancer. 1800 mRNA diagnostic biomarker "EWSR1,TAF2N,CHN1" human tissue chondrosarcoma extraskeletal myxoid chondrosarcoma uncertain original research 11679947 "Extraskeletal myxoid chondrosarcoma: a clinicopathologic, immunohistochemical, and molecular analysis of 18 cases." 1801 mRNA diagnostic biomarker TERT human tissue lung cancer non-small cell lung cancer H original research 11679180 Clinicopathologic significance of telomerase activity and hTERT mRNA expression in non-small cell lung cancer. 1802 mRNA diagnostic biomarker PAPPA2 human plasma breast cancer uncertain original research 11597188 The characterization of pregnancy associated plasma protein-E and the identification of an alternative splice variant. 1803 mRNA diagnostic biomarker YBX1 human uncertain lung cancer non-small cell lung cancer uncertain original research 11595709 "Nuclear expression of the Y-box binding protein, YB-1, as a novel marker of disease progression in non-small cell lung cancer." 1804 mRNA diagnostic biomarker PNET human tissue primitive neuroectodermal tumor of the uteru uncertain original research 11584489 Primitive neuroectodermal tumor of the uterus. A case report. 1805 mRNA diagnostic biomarker MME human tissue hepatocellular cancer H original research 11583969 cDNA arrays and immunohistochemistry identification of CD10/CALLA expression in hepatocellular carcinoma. 1806 mRNA diagnostic biomarker UCHL1 human uncertain spindle cell sarcoma H original research 11570907 Expression of protein gene product 9.5 in epithelioid and conventional malignant peripheral nerve sheath tumors. 1807 mRNA diagnostic biomarker IGF2 human uncertain adrenocortical cancer H original research 11559548 Molecular markers and long-term recurrences in a large cohort of patients with sporadic adrenocortical tumors. 1808 mRNA diagnostic biomarker EIF4G human "tissue,serum" lung cancer squamous cell lung carcinoma H original research 11550153 "Translation initiation factor eIF-4G is immunogenic, overexpressed, and amplified in patients with squamous cell lung carcinoma." 1809 mRNA diagnostic biomarker AFP human uncertain hepatocellular cancer H original research 11522637 "A hepatocellular carcinoma-specific adenovirus variant, CV890, eliminates distant human liver tumors in combination with doxorubicin." 1810 mRNA diagnostic biomarker TP73 human uncertain breast cancer H original research 11510689 Wild type p73 overexpression and high-grade malignancy in breast cancer. 1811 mRNA diagnostic biomarker KLK10 human tissue ovarian cancer epithelial ovarian carcinoma H original research 11489815 Prognostic value of human kallikrein 10 expression in epithelial ovarian carcinoma. 1812 mRNA diagnostic biomarker GCK human tissue ovarian cancer serous ovarian carcinoma H original research 11489814 Human kallikrein 4 (KLK4) is highly expressed in serous ovarian carcinomas. 1813 mRNA diagnostic biomarker TP63 human tissue breast cancer H original research 11474290 "p63, a p53 homologue, is a selective nuclear marker of myoepithelial cells of the human breast." 1814 mRNA diagnostic biomarker PTEN human tissue breast cancer L original research 11454999 Loss of expression of the PTEN gene protein product is associated with poor outcome in breast cancer. 1815 mRNA diagnostic biomarker PLK1 human tissue uterine cancer endometrial cancer H original research 11410324 Polo-like kinase (PLK) expression in endometrial carcinoma. 1816 mRNA diagnostic biomarker UCHL1 human uncertain nerve sheath tumor H original research 11401673 Expression of PGP 9.5 in granular cell nerve sheath tumors: an immunohistochemical study of six cases. 1817 mRNA diagnostic biomarker PSCA human tissue pancreatic cancer H original research 11389052 Discovery of new markers of cancer through serial analysis of gene expression: prostate stem cell antigen is overexpressed in pancreatic adenocarcinoma. 1818 mRNA diagnostic biomarker LMP-1 human uncertain nasopharyngeal cancer uncertain original research 11359135 Differentiation of recurrent nasopharyngeal carcinoma and skull base osteoradionecrosis by Epstein-Barr virus-derived latent membrane protein-1 gene. 1819 mRNA diagnostic biomarker GPX3 human tissue ovarian cancer H original research 11358798 Coordinately up-regulated genes in ovarian cancer. 1820 mRNA diagnostic biomarker RET human uncertain uncertain H review 11338505 Molecular diagnosis of multiple type 2 endocrine neoplasia. 1821 mRNA diagnostic biomarker "MKI67,TP53,NME1" human tissue bladder cancer H(TP53) original research 11326661 "Immunohistochemical examinations (Ki67, p53, nm23) and DNA cytophotometry in bladder cancer." 1822 mRNA diagnostic biomarker MIB1 human tissue breast cancer breast phyllodes cancer H original research 11314782 p53 protein expression and gene mutation in phyllodes tumors of the breast. 1823 mRNA diagnostic biomarker KLK8 human "tissue,serum" ovarian cancer L original research 11309326 The human KLK8 (neuropsin/ovasin) gene: identification of two novel splice variants and its prognostic value in ovarian cancer. 1824 mRNA diagnostic biomarker TP53 human uncertain tonsillar cancer H original research 11299799 Human papilloma virus (HPV) and p53 immunostaining in advanced tonsillar carcinoma--relation to radiotherapy response and survival. 1825 mRNA diagnostic biomarker MSI1 human tissue glioma H original research 11284014 Expression of the neural RNA-binding protein Musashi1 in human gliomas. 1826 mRNA diagnostic biomarker MMP12 human tissue colorectal cancer L original research 11283927 Human macrophage metalloelastase gene expression in colorectal carcinoma and its clinicopathologic significance. 1827 mRNA diagnostic biomarker KLK10 human serum ovarian cancer H original research 11282101 Human kallikrein 10: a novel tumor marker for ovarian carcinoma? 1828 mRNA diagnostic biomarker "APE1,APEX2" human uncertain germ cell cancer H original research 11280790 Altered expression of Ape1/ref-1 in germ cell tumors and overexpression in NT2 cells confers resistance to bleomycin and radiation. 1829 mRNA diagnostic biomarker BPIFA1 human tissue lung cancer non-small-cell lung cancer H(LUNX) original research 11251963 "Isolation of a novel human lung-specific gene, LUNX, a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer." 1830 mRNA diagnostic biomarker CA15P3 human serum breast cancer H original research 11251942 G-CSF induces elevation of circulating CA 15-3 in breast carcinoma patients treated in an adjuvant setting. 1831 mRNA diagnostic biomarker C1orf137 human "tissue,plasma" prostate cancer H original research 11245466 "Identification and characterization of prostein, a novel prostate-specific protein." 1832 mRNA diagnostic biomarker HSP105 human "tissue,serum" pancreatic cancer H original research 11237751 Gene cloning of immunogenic antigens overexpressed in pancreatic cancer. 1833 mRNA diagnostic biomarker TP53 human tissue bladder cancer bladder transitional cell carcinoma H original research 11223675 Relevance of p53 gene alterations for tumor recurrence in patients with superficial transitional cell carcinoma of the bladder. 1834 mRNA diagnostic biomarker "GYPA,CAIX" human tissue renal cancer H original research 11215204 MN/CA IX antigen as a potential target for renal cell carcinoma. 1835 mRNA diagnostic biomarker SERPINB5 human uncertain breast cancer L original research 11206999 Maspin--a novel protease inhibitor with tumor-suppressing activity in breast cancer. 1836 mRNA diagnostic biomarker PLK1 human tissue ovarian cancer H original research 11166914 Expression of polo-like kinase in ovarian cancer is associated with histological grade and clinical stage. 1837 mRNA diagnostic biomarker TP53 human serum melanoma H original research 11139313 p53 autoantibodies in patients with malignant mesothelioma: stability through disease progression. 1838 mRNA diagnostic biomarker KLK6 human serum ovarian cancer H original research 11124344 Human kallikrein 6 (zyme/protease M/neurosin): a new serum biomarker of ovarian carcinoma. 1839 mRNA diagnostic biomarker KRT19 human tissue oral cancer uncertain original research 11098092 Keratin mRNA for detecting micrometastasis in cervical lymph nodes of oral cancer. 1840 mRNA diagnostic biomarker HMGI human tissue neuroblastoma H original research 11076660 Expression of the HMGI(Y) gene products in human neuroblastic tumours correlates with differentiation status. 1841 mRNA diagnostic biomarker TADG human tissue ovarian cancer H original research 11068177 Ovarian tumor cells express a novel multi-domain cell surface serine protease. 1842 mRNA diagnostic biomarker RBM human tissue germ cell cancer L original research 11014580 Absence of RBM expression as a marker of intratubular (in situ) germ cell neoplasia of the testis. 1843 mRNA diagnostic biomarker KLK15 human tissue prostate cancer H original research 11010966 Molecular cloning of the human kallikrein 15 gene (KLK15). Up-regulation in prostate cancer. 1844 mRNA diagnostic biomarker "CD56,CD57,CD99" human uncertain neuroblastoma uncertain review 10968705 Immunohistology of neuroendocrine and neuroectodermal tumors. 1845 mRNA diagnostic biomarker EGFR human uncertain uncertain H original research 10963135 "Modulation of EGFR gene transcription by secondary structures, a polymorphic repetitive sequence and mutations--a link between genetics and epigenetics." 1846 mRNA diagnostic biomarker TP53 human uncertain nasopharyngeal cancer H original research 10918601 High level expression of deltaN-p63: a mechanism for the inactivation of p53 in undifferentiated nasopharyngeal carcinoma (NPC)? 1847 mRNA diagnostic biomarker CEACAM5 human uncertain lung cancer uncertain review 10897844 Biological markers and exposure to asbestos. 1848 mRNA diagnostic biomarker MIB1 human tissue adenoid cystic cancer H original research 10897109 "Adenoid cystic carcinoma: use of cell proliferation, BCL-2 expression, histologic grade, and clinical stage as predictors of clinical outcome." 1849 mRNA diagnostic biomarker SERPINB4 human tissue cervical cancer cervical squamous cell carcinoma H original research 10873412 Immunoreactivity of recombinant squamous cell carcinoma antigen and leupin/SCCA-2: implications for tumor marker detection. 1850 mRNA diagnostic biomarker HMGI human tissue pancreatic cancer pancreatic ductal adenocarcinoma H original research 10866296 Pancreatic duct cell carcinomas express high levels of high mobility group I(Y) proteins. 1851 mRNA diagnostic biomarker GOLGA4 human "tissue,serum" hepatocellular cancer H original research 10860485 Functional arrangement of genomic DNA and structure of nuclear matrix. 1852 mRNA diagnostic biomarker SCCA human uncertain head and neck cancer uncertain original research 10845558 Genetic diagnosis of micrometastasis based on SCC antigen mRNA in cervical lymph nodes of head and neck cancer. 1853 mRNA diagnostic biomarker MT3 human uncertain bladder cancer H original research 10811567 Metallothionein isoform 3 as a potential biomarker for human bladder cancer. 1854 mRNA diagnostic biomarker WT1 human blood leukaemia H original research 10804819 "Genetic diagnosis of leukemia: diagnosis of relapse and complete remission, and prediction of leukemia onset." 1855 mRNA diagnostic biomarker "E2F1,CDKN2AINK4A" human uncertain lymphoma diffuse large B cell lymphoma H(CDKN2A) original research 10803523 Frequent disruption of the RB1 pathway in diffuse large B cell lymphoma: prognostic significance of E2F-1 and p16INK4A. 1856 mRNA diagnostic biomarker "MDM2,CDK4" human uncertain lipoblastoma H original research 10727978 "Coordinated expression and amplification of the MDM2, CDK4, and HMGI-C genes in atypical lipomatous tumours." 1857 mRNA diagnostic biomarker TP53 human serum colorectal cancer H original research 10703073 Serum p53 antibody assay: evaluation in colorectal cancer. 1858 mRNA diagnostic biomarker TP53 human uncertain bladder cancer H review 10696247 A critical analysis of the use of p53 as a marker for management of bladder cancer. 1859 mRNA diagnostic biomarker CD44 human tissue uncertain H review 10694938 CD44 cell adhesion molecules. 1860 mRNA diagnostic biomarker "WT1,MDR" human tissue Wilms' tumor H(WT1) original research 10687307 The role of Wilms' tumor genes. 1861 mRNA diagnostic biomarker MEN1 human uncertain endocrine cancer uncertain original research 10664520 MEN1 gene mutation analysis in Italian patients with multiple endocrine neoplasia type 1. 1862 mRNA diagnostic biomarker TP53 human blood head and neck cancer head and neck squamous cell carcinoma H original research 10645403 p53 tumor suppressor gene as a clonal marker in head and neck squamous cell carcinoma: p53 mutations in primary tumor and matched lymph node metastases. 1863 mRNA diagnostic biomarker ACBD3 human serum breast cancer H original research 10639166 Extracellular protein kinase A as a cancer biomarker: its expression by tumor cells and reversal by a myristate-lacking Calpha and RIIbeta subunit overexpression. 1864 mRNA diagnostic biomarker MDK human tissue hepatocellular cancer H original research 10626184 Expression of the midkine gene in human hepatocellular carcinomas. 1865 mRNA diagnostic biomarker FHIT human tissue gastric cancer gastric adenocarcinoma L original research 10618602 Fhit expression in gastric adenocarcinoma: correlation with disease stage and survival. 1866 mRNA diagnostic biomarker TP63 human uncertain squamous cell cancer H original research 10594758 Association of p63 with proliferative potential in normal and neoplastic human keratinocytes. 1867 mRNA diagnostic biomarker BMP6 human tissue cell cancer uncertain original research 10582704 Bone morphogenetic protein-6 is a marker of serous acinar cell differentiation in normal and neoplastic human salivary gland. 1868 mRNA diagnostic biomarker "GYPA,CA9" human tissue renal cancer H original research 10574265 MN/CA IX/G250 as a potential target for immunotherapy of renal cell carcinomas. 1869 mRNA diagnostic biomarker KAI1 human tissue colorectal cancer "H(earlier),L(advanced)" original research 10568187 Reduced expression of the metastasis suppressor gene KAI1 in advanced colon cancer and its metastases. 1870 mRNA diagnostic biomarker GYPA human blood renal cancer H original research 10500965 Molecular detection of circulating cancer cells in patients with renal cell carcinoma. 1871 mRNA diagnostic biomarker TADG14 human uncertain ovarian cancer H original research 10485494 "Cloning of tumor-associated differentially expressed gene-14, a novel serine protease overexpressed by ovarian carcinoma." 1872 mRNA diagnostic biomarker "EGFR,TP53" human serum lung cancer H original research 10471051 "p53 protein, EGF receptor, and anti-p53 antibodies in serum from patients with occupationally derived lung cancer." 1873 mRNA diagnostic biomarker GATA4 "mice,human" tissue adrenocortical cancer L original research 10449810 Reciprocal changes in the expression of transcription factors GATA-4 and GATA-6 accompany adrenocortical tumorigenesis in mice and humans. 1874 mRNA diagnostic biomarker BTK human tissue gastric cancer H original research 10430078 tie-1 protein tyrosine kinase: a novel independent prognostic marker for gastric cancer. 1875 mRNA diagnostic biomarker S100 human serum melanoma uncertain original research 10354916 "S-100 beta protein in serum, a tumor marker in malignant melanoma-- current state of knowledge and clinical experience." 1876 mRNA diagnostic biomarker TP53 human "tissue,serum" gastric cancer H original research 10337171 Protein p53 in gastric carcinoma: clinical use of cancer research on neoplasms. 1877 mRNA diagnostic biomarker PLAG1 human tissue adenocarcinoma H original research 10334569 Pleomorphic adenoma gene 1 is expressed in cultured benign and malignant salivary gland tumor cells. 1878 mRNA diagnostic biomarker TCFL5 human uncertain cervical cancer H original research 10334523 Detection of human papillomavirus types 16 and 18 mRNA in peripheral blood of advanced cervical cancer patients and its association with prognosis. 1879 mRNA diagnostic biomarker LSP1 human "tissue,plasma" lymphoma uncertain original research 10233704 Lymphocyte-specific protein 1: a specific marker of human leucocytes. 1880 mRNA diagnostic biomarker ERBB2 human tissue cervical cancer H original research 10190316 Prognostic significance of c-erbB-2 protein expression in carcinoma of the cervix treated with radiotherapy. 1881 mRNA diagnostic biomarker PSP94 mice tissue prostate cancer uncertain original research 10025505 "cDNA, genomic cloning, and gene expression analysis of mouse PSP94 (prostate secretory protein of 94 amino acids)." 1882 mRNA diagnostic biomarker ECT2L human uncertain neuroblastoma L original research 9952112 "The basic helix-loop-helix transcription factor dHAND, a marker gene for the developing human sympathetic nervous system, is expressed in both high- and low-stage neuroblastomas." 1883 mRNA diagnostic biomarker HMGI human tissue lung cancer non-small lung cancer H original research 9858904 HMGIC expression patterns in non-small lung cancer and surrounding tissue. 1884 mRNA diagnostic biomarker TP53 human serum hepatocellular cancer H original research 9849479 Clinical evaluation of autoantibodies to p53 protein in patients with chronic liver disease and hepatocellular carcinoma. 1885 mRNA diagnostic biomarker WT1 human uncertain Wilms' tumor H original research 9820865 Desmoplastic small round cell tumor: RT-PCR analysis and immunohistochemical detection of the Wilm's tumor gene WT1. 1886 mRNA diagnostic biomarker SSTR2 human uncertain neuroblastoma H original research 9816127 Quantitation of somatostatin receptor type 2 gene expression in neuroblastoma cell lines and primary tumors using competitive reverse transcription-polymerase chain reaction. 1887 mRNA diagnostic biomarker TP53 human uncertain bladder cancer H original research 9815851 Relationship of tumor angiogenesis and nuclear p53 accumulation in invasive bladder cancer. 1888 mRNA diagnostic biomarker CDKN1A human tissue lung cancer lung squamous cell cancer H(p21) original research 9815570 p21 expression as a predictor for favorable prognosis in squamous cell carcinoma of the lung. 1889 mRNA diagnostic biomarker TP53 human serum lung cancer non-small-cell lung cancer H original research 9790550 Clinical implications of p53 autoantibodies in the sera of patients with non-small-cell lung cancer. 1890 mRNA diagnostic biomarker "TLS,FUS,DDIT3" human tissue sarcoma uncertain original research 9785008 Detection of TLS/FUS-CHOP fusion transcripts in myxoid and round cell liposarcomas by nested reverse transcription-polymerase chain reaction using archival paraffin-embedded tissues. 1891 mRNA diagnostic biomarker MMP12 human tissue hepatocellular cancer H original research 9755235 Expression of human macrophage metalloelastase gene in hepatocellular carcinoma: correlation with angiostatin generation and its clinical significance. 1892 mRNA diagnostic biomarker TP53 human tissue leukaemia H original research 9719458 p53 may mediate the mdr-1 expression via the WT1 gene in human vincristine-resistant leukemia/lymphoma cell lines. 1893 mRNA diagnostic biomarker MDK human uncertain gastrointestinal cancer H original research 9716029 Truncated midkine as a marker of diagnosis and detection of nodal metastases in gastrointestinal carcinomas. 1894 mRNA diagnostic biomarker S100A7 human uncertain breast cancer H review 9693957 Psoriasin (S100A7). 1895 mRNA diagnostic biomarker GRNA human "tissue,serum" prostate cancer H original research 9690660 "Granin-A, parathyroid hormone-related protein, and calcitonin gene products in neuroendocrine prostate cancer." 1896 mRNA diagnostic biomarker "ERBB2,NEU,MKI67,TP53" human uncertain breast cancer "H(ERBB2,TP53)" original research 9676832 Analysis of p53 gene mutation by polymerase chain reaction-single strand conformation polymorphism provides independent prognostic information in node-negative breast cancer. 1897 mRNA diagnostic biomarker MIBI human uncertain uncertain L original research 9669397 Involvement of glutathione in loss of technetium-99m-MIBI accumulation related to membrane MDR protein expression in tumor cells. 1898 mRNA diagnostic biomarker CD44 human tissue uncertain H review 9634541 Clinical implications of anomalous CD44 gene expression in neoplasia. 1899 mRNA diagnostic biomarker TP53 human "tissue,serum" dermoid cyst H original research 9631595 Immunohistochemical and molecular studies on malignant transformation in mature cystic teratoma of the ovary. 1900 mRNA diagnostic biomarker TP53 human tissue germ cell cancer H original research 9562446 Ageneticperspectiveofmalegermcelltumors. 1901 mRNA diagnostic biomarker TWSG1 human uncertain head and neck cancer head and neck squamous cell carcinoma L original research 9484941 9p21 deletion correlates with recurrence in head and neck cancer. 1902 mRNA diagnostic biomarker PSCA human tissue prostate cancer H original research 9465086 Prostate stem cell antigen: a cell surface marker overexpressed in prostate cancer. 1903 mRNA diagnostic biomarker "ETV6,NTRK3" human uncertain fibromatose uncertain original research 9462753 A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma. 1904 mRNA diagnostic biomarker TP53 human "tissue,serum" "lung cancer,mesothelioma" H original research 9329647 "Mutations, tissue accumulations, and serum levels of p53 in patients with occupational cancers from asbestos and silica exposure." 1905 mRNA diagnostic biomarker CDH1 human tissue esophageal cancer L original research 9301546 Expression of E-cadherin in oesophageal carcinomas from the UK and China: disparities in prognostic significance. 1906 mRNA diagnostic biomarker CD44 human tissue colon cancer H original research 9242440 Rapid analysis of distinctive CD44 RNA splicing preferences that characterize colonic tumors. 1907 mRNA diagnostic biomarker "PLAU,SERBP1P2" human tissue uncertain H original research 9198168 Clinical impact of the plasminogen activation system in tumor invasion and metastasis: prognostic relevance and target for therapy. 1908 mRNA diagnostic biomarker PSP94 human tissue prostate cancer H original research 9174167 Molecular cloning and gene expression analysis of PSP94 (prostate secretory protein of 94 amino acids) in primates. 1909 mRNA diagnostic biomarker "PAX3,FOXO1,PAX7" olive baboon tissue rhabdomyosarcoma uncertain original research 9098647 Detection of gene fusions in rhabdomyosarcoma by reverse transcriptase-polymerase chain reaction assay of archival samples. 1910 mRNA diagnostic biomarker "MDM2,TP53" human uncertain lipoblastoma H original research 9071998 Distinct mdm2/p53 expression patterns in liposarcoma subgroups: implications for different pathogenetic mechanisms. 1911 mRNA diagnostic biomarker TP53 human sputum squamous cell cancer H original research 9027617 Examination of p53 alterations and cytokeratin expression in sputa collected from patients prior to histological diagnosis of squamous cell carcinoma. 1912 mRNA diagnostic biomarker SFTPB human tissue lung cancer non-small-cell lung cancer uncertain original research 9021728 Expression of surfactant protein B precursor and surfactant protein B mRNA in adenocarcinoma of the lung. 1913 mRNA diagnostic biomarker PSMA human uncertain prostate cancer H review 8999630 Significance of prostate-specific membrane antigen (PSMA). A neurocarboxypeptidase and membrane folate hydrolase. 1914 mRNA diagnostic biomarker RB1 human tissue oral cancer L original research 8944840 Absence of retinoblastoma gene product in human primary oral cavity carcinomas. 1915 mRNA diagnostic biomarker CD44 human tissue "breast cancer,bladder cancer,colon cancer" H original research 8909242 "Analysis of anomalous CD44 gene expression in human breast, bladder, and colon cancer and correlation of observed mRNA and protein isoforms." 1916 mRNA diagnostic biomarker TMPRSS4 human tissue "prostate cancer,ovarian cancer,breast cancer" H original research 8898378 A novel protease homolog differentially expressed in breast and ovarian cancer. 1917 mRNA diagnostic biomarker NME1 human uncertain ovarian cancer L original research 8868173 Diagnostic and biological determinants in undifferentiated and poorly differentiated ovarian carcinomas. 1918 mRNA diagnostic biomarker ABCC1 human uncertain leukaemia L original research 8833390 The biological significance of the multidrug resistance gene MRP in inversion 16 leukemias. 1919 mRNA diagnostic biomarker "ERBB2,NEU" human serum "ovarian cancer,breast cancer" H review 8796816 The role of the HER-2/neu oncogene in gynecologic cancers. 1920 mRNA diagnostic biomarker "ACPP,PSAT1" human tissue prostate cancer H review 8774111 "Human prostatic acid phosphatase and prostate specific antigen: protein structure, gene organization, and expression in neoplastic and benign tissues." 1921 mRNA diagnostic biomarker TP53 human uncertain esophageal cancer H original research 8732116 Expression of p53 in human esophageal carcinoma and pre-malignant lesions in the esophagus. 1922 mRNA diagnostic biomarker COSVIC human tissue prostate cancer H original research 8705997 Two differentially expressed genes in normal human prostate tissue and in carcinoma. 1923 mRNA diagnostic biomarker TPO rat tissue thyroid cancer papillary thyroid carcinoma L original research 8691351 Immunohistochemical loss of thyroid peroxidase in papillary thyroid carcinoma: strong suppression of peroxidase gene expression. 1924 mRNA diagnostic biomarker YES1 human tissue colon cancer H original research 8674385 Expression of protooncogene-encoded mRNA by colonic epithelial cells in inflammatory bowel disease. 1925 mRNA diagnostic biomarker "HRAS,TFG" human uncertain nephroblastoma H(TFG) original research 8658015 Genetic clinical markers of human neuroblastoma with special reference to N-myc oncogene: amplified or not amplified?--An overview. 1926 mRNA diagnostic biomarker CD44 human tissue colon cancer H original research 8655705 Detection of exfoliated carcinoma cells in colonic luminal washings by identification of deranged patterns of expression of the CD44 gene. 1927 mRNA diagnostic biomarker TP53 human "tissue,serum" hepatocellular cancer H original research 8655704 Use of specific ELISA for the detection of antibodies directed against p53 protein in patients with hepatocellular carcinoma. 1928 mRNA diagnostic biomarker TP53 human tissue bladder cancer H original research 8652250 p53 overexpression as a prognostic factor for advanced stage bladder cancer. 1929 mRNA diagnostic biomarker "MRP1,CD9" human uncertain breast cancer L original research 8640807 Motility-related protein-1 (MRP-1/CD9) reduction as a factor of poor prognosis in breast cancer. 1930 mRNA diagnostic biomarker NPEPPS human tissue prostate cancer L original research 8636136 Prostate-specific antigen expression is regulated by an upstream enhancer. 1931 mRNA diagnostic biomarker SRRM1 human uncertain bladder cancer uncertain original research 8603421 Bladder cancer-associated nuclear matrix proteins. 1932 mRNA diagnostic biomarker TP53 human tissue melanoma H original research 8436341 p53 protein expression in non-neoplastic lesions and benign and malignant neoplasms of soft tissue. 1933 mRNA diagnostic biomarker TP53 human tissue bronchial neoplasia H original research 8402667 p53 protein accumulates frequently in early bronchial neoplasia. 1934 mRNA diagnostic biomarker MDK human tissue Wilms' tumor H original research 8383007 A new family of heparin-binding growth/differentiation factors: increased midkine expression in Wilms' tumor and other human carcinomas. 1935 mRNA diagnostic biomarker TP53 human tissue lung cancer H original research 8287223 Application of the p53 gene mutation pattern for differential diagnosis of primary versus metastatic lung carcinomas. 1936 mRNA diagnostic biomarker TP53 human tissue cutaneous cancer non-melanoma skin cancer H original research 8286219 The relation between p53 mutation and p53 immunostaining in non-melanoma skin cancer. 1937 mRNA diagnostic biomarker HMGI human uncertain prostate cancer H original research 8221692 Increased expression of high mobility group protein I(Y) in high grade prostatic cancer determined by in situ hybridization. 1938 mRNA diagnostic biomarker "KRAS,TP53" human tissue pancreatic cancer H original research 8178941 Detection of K-ras mutations in mucinous pancreatic duct hyperplasia from a patient with a family history of pancreatic carcinoma. 1939 mRNA diagnostic biomarker TP53 human tissue gastric cancer H original research 8130938 p53 overexpression as a marker of malignancy in gastric biopsies. 1940 mRNA diagnostic biomarker "ERBB2,NEU" human "tissue,serum" breast cancer H original research 8101229 Stability of HER-2/neu expression over time and at multiple metastatic sites. 1941 mRNA diagnostic biomarker "MDM2,TP53" human uncertain bladder cancer H original research 8064890 Altered patterns of MDM2 and TP53 expression in human bladder cancer. 1942 mRNA diagnostic biomarker WT1 human uncertain leukaemia H original research 7949179 WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia. 1943 mRNA diagnostic biomarker TP53 human uncertain oral cancer H original research 7932243 Association of overexpression of p53 oncoprotein with the state of cell proliferation in oral carcinoma. 1944 mRNA diagnostic biomarker "ERBB2,RAS" human tissue breast cancer H original research 7915096 Prognostic and predictive relevance of c-erbB-2 and ras expression in node positive and negative breast cancer. 1945 mRNA diagnostic biomarker ERBB human "tissue,serum" ovarian cancer H original research 7908021 Elevated serum levels of a c-erbB-2 oncogene product in ovarian cancer patients and in pregnancy. 1946 mRNA diagnostic biomarker TP53 human uncertain lymphoma H original research 7773162 p53 expression in non-Hodgkin's lymphomas: a marker of p53 inactivation? 1947 mRNA diagnostic biomarker ERBB human uncertain bladder cancer H original research 7757996 C-erbB-2 gene amplification: a molecular marker in recurrent bladder tumors? 1948 mRNA diagnostic biomarker "KRAS,TP53" human uncertain pancreatic cancer H(TP53) original research 7730480 Molecular markers for diagnostic cytology of neoplasms in the head region of the pancreas: mutation of K-ras and overexpression of the p53 protein product. 1949 mRNA diagnostic biomarker TP53 human serum pancreatic cancer H original research 7698709 Antibodies against p53 protein in serum of patients with benign or malignant pancreatic and biliary diseases. 1950 mRNA diagnostic biomarker TP53 mice tissue bladder cancer transitional cell bladder carcinoma H original research 7677935 Nuclear overexpression of p53 protein in transitional cell bladder carcinoma: a marker for disease progression. 1951 mRNA diagnostic biomarker UCHL1 human "tissue,serum" adenoid cystic cancer H original research 7671453 Protein gene product (PGP) 9.5 in diagnostic (neuro-) oncology. An immunomorphological study. 1952 mRNA diagnostic biomarker TP53 human tissue bladder cancer transitional cell bladder carcinoma H original research 7660508 Evaluation of overexpression of p53 tumor suppressor protein in superficial and invasive transitional cell bladder cancer: comparison with DNA ploidy. 1953 mRNA diagnostic biomarker NF1 human tissue brain tumor L original research 7657385 Analysis of the GAP-related domain of the neurofibromatosis type 1 (NF1) gene in childhood brain tumors. 1954 mRNA diagnostic biomarker PRAM1 human uncertain leukaemia uncertain original research 7628753 The PML/RAR alpha fusion gene in the diagnosis and monitoring of acute promyelocytic leukemia. 1955 mRNA diagnostic biomarker ERBB human serum breast cancer H original research 7605658 Detection of c-erbB-2 related protein in sera from breast cancer patients. Relationship to ERBB2 gene amplification and c-erbB-2 protein overexpression in tumour. 1956 mRNA diagnostic biomarker CD44 human tissue breast cancer H original research 7585612 CD44 isoforms correlate with cellular differentiation but not with prognosis in human breast cancer. 1957 mRNA diagnostic biomarker TCF1 human tissue T-lineage cancer L original research 7579399 The human TCF-1 gene encodes a nuclear DNA-binding protein uniquely expressed in normal and neoplastic T-lineage lymphocytes. 1958 mRNA diagnostic biomarker RET human tissue neuroblastoma H original research 7567689 Ret-oncogene expression correlates with neuronal differentiation of neuroblastic tumors. 1959 mRNA diagnostic biomarker SCG5 human uncertain lung cancer H original research 2545336 Differential expression of the gene encoding the novel pituitary polypeptide 7B2 in human lung cancer cells. 1960 mRNA diagnostic biomarker CGRP human serum thyroid cancer medullary carcinoma of the thyroi H original research 2412687 Medullary carcinoma of the thyroid. An immunocytochemical and histochemical study of 25 cases using eight separate markers. 1961 mRNA diagnostic biomarker CGRP human plasma "lung cancer,thyroid cancer" H original research 2408883 Expression of the human calcitonin/CGRP gene in lung and thyroid carcinoma. 1962 mRNA diagnostic biomarker PSEN2 human tissue breast cancer uncertain original research 2223388 "The pS2 gene, mRNA, and protein: a potential marker for human breast cancer." 1963 mRNA diagnostic biomarker TP53 human uncertain breast cancer H original research 1961733 Mutations in p53 as potential molecular markers for human breast cancer. 1964 mRNA diagnostic biomarker "BCR,ABL1" human uncertain leukaemia uncertain original research 1931706 The molecular pathology of chronic myelogenous leukaemia. 1965 mRNA diagnostic biomarker LITAF human tissue "hepatocellular cancer,colorectal cancer" L original research 1699834 Liver fatty acid-binding protein: a marker for studying cellular differentiation in gut epithelial neoplasms. 1966 mRNA diagnostic biomarker RB1 human blood retinoblastoma L original research 1670986 Diagnosis of a predisposition of retinoblastoma at the DNA level. 1967 mRNA diagnostic biomarker RB1 human tissue bladder cancer L original research 1640485 Altered expression of retinoblastoma protein and known prognostic variables in locally advanced bladder cancer. 1968 mRNA diagnostic biomarker RPS2 "rat,mice" tissue uncertain H original research 1586449 Elevated expression of the ribosomal protein S2 gene in human tumors. 1969 mRNA diagnostic biomarker TP53 human tissue neuroblastoma H original research 1364172 Abnormal p53 expression in lung neuroendocrine tumors. Diagnostic and prognostic implications. 1970 mRNA diagnostic biomarker TP53 human uncertain breast cancer H original research 1357956 "p53 and c-erbB-2 protein expression in breast carcinomas. An immunohistochemical study including correlations with receptor status, proliferation markers, and clinical stage in human breast cancer." 1971 mRNA diagnostic biomarker ERBB2 human tissue salivary cancer salivary gland cancer H original research 1353853 Immunohistochemical study of c-erbB-2 oncoprotein overexpression in human major salivary gland carcinoma: an indicator of aggressiveness. 1972 mRNA diagnostic biomarker ERBB2 human tissue gastric cancer gastric adenocarcinoma H original research 1348293 Clinicopathological significance of c-erbB-2 protein expression in human gastric carcinoma. 1973 mRNA diagnostic biomarker SCG2 human uncertain Ewing sarcoma H original research 1342962 Secretogranin II expression in Ewing's sarcomas and primitive neuroectodermal tumors. 1974 mRNA diagnostic biomarker GYPA human serum ovarian cancer uncertain original research 1306294 Expression of Mn-superoxide dismutase in carcinogenesis.